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Volumn 284, Issue 3 47-3, 2003, Pages

The melanocortin system

Author keywords

Inflammation; Obesity; Pigmentation; Receptor; Sexual function

Indexed keywords

MELANOCORTIN; MELANOCORTIN RECEPTOR;

EID: 0037372451     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00434.2002     Document Type: Short Survey
Times cited : (404)

References (54)
  • 1
    • 0032694319 scopus 로고    scopus 로고
    • Neuropeptides and sexual behavior
    • Argiolas A. Neuropeptides and sexual behavior. Neurosci Biobehav Rev 8: 1127-1142, 1999.
    • (1999) Neurosci Biobehav Rev , vol.8 , pp. 1127-1142
    • Argiolas, A.1
  • 2
    • 0034014197 scopus 로고    scopus 로고
    • ACTH-and α-MSH-induced grooming, stretching, yawning and penile erection in male rats: Site of action in the brain and role of melanocortin receptors
    • Argiolas A, Melis MR, Murgia S, and Schiöth HB. ACTH-and α-MSH-induced grooming, stretching, yawning and penile erection in male rats: site of action in the brain and role of melanocortin receptors. Brain Res Bull 51: 425-434, 2000.
    • (2000) Brain Res Bull , vol.51 , pp. 425-434
    • Argiolas, A.1    Melis, M.R.2    Murgia, S.3    Schiöth, H.B.4
  • 3
    • 0025038674 scopus 로고
    • Altered expression of hypothalamic neuropeptide mRNAs in food-restricted and food-deprived rats
    • Brady LS, Smith MA, Gold PW, and Herkenham H. Altered expression of hypothalamic neuropeptide mRNAs in food-restricted and food-deprived rats. Neuroendocrinology 52: 441-447, 1990.
    • (1990) Neuroendocrinology , vol.52 , pp. 441-447
    • Brady, L.S.1    Smith, M.A.2    Gold, P.W.3    Herkenham, H.4
  • 5
    • 0033567075 scopus 로고    scopus 로고
    • Changes in neuropeptide Y receptors and pro-opiomelanocortin in the anorexia (anx/anx) mouse hypothalamus
    • Broberger C, Johansen J, Brismar H, Johansson C, Schalling M, and Hökfelt T. Changes in neuropeptide Y receptors and pro-opiomelanocortin in the anorexia (anx/anx) mouse hypothalamus. J Neurosci 19: 7130-7139, 1999.
    • (1999) J Neurosci , vol.19 , pp. 7130-7139
    • Broberger, C.1    Johansen, J.2    Brismar, H.3    Johansson, C.4    Schalling, M.5    Hökfelt, T.6
  • 6
    • 0027049534 scopus 로고
    • Molecular characterization of the mouse agouti locus
    • Bultman SJ, Michaud EJ, and Woychik RP. Molecular characterization of the mouse agouti locus. Cell 71: 1195-1204, 1992.
    • (1992) Cell , vol.71 , pp. 1195-1204
    • Bultman, S.J.1    Michaud, E.J.2    Woychik, R.P.3
  • 7
    • 0032055121 scopus 로고    scopus 로고
    • Binding of α-melanocyte-stimulating hormone to its G-protein-coupled receptor on B-lymphocytes activates the Jak/Stat pathway
    • Buggy JJ. Binding of α-melanocyte-stimulating hormone to its G-protein-coupled receptor on B-lymphocytes activates the Jak/Stat pathway. Biochern J 331: 211-216, 1998.
    • (1998) Biochern J , vol.331 , pp. 211-216
    • Buggy, J.J.1
  • 8
    • 0033803235 scopus 로고    scopus 로고
    • α-Melanocyte-stimulating hormone in normal human physiology and disease states
    • Catania A, Airaghi L, Colombo G, and Lipton JM. α-Melanocyte-stimulating hormone in normal human physiology and disease states. Trends Endocrinol Metab 11: 304-308, 2000.
    • (2000) Trends Endocrinol Metab , vol.11 , pp. 304-308
    • Catania, A.1    Airaghi, L.2    Colombo, G.3    Lipton, J.M.4
  • 9
    • 0029848043 scopus 로고    scopus 로고
    • Distribution of cDNA for melanocortin receptor subtypes in human tissues
    • Chhajlani V. Distribution of cDNA for melanocortin receptor subtypes in human tissues. Biochem Mol Biol Int 38: 73-80, 1996.
    • (1996) Biochem Mol Biol Int , vol.38 , pp. 73-80
    • Chhajlani, V.1
  • 11
    • 0031442053 scopus 로고    scopus 로고
    • Exocrine gland dysfunction in MC5-R-deficient mice: Evidence for coordinated regulation of exocrine gland function by melanocortin peptides
    • Chen W, Kelly MA, Opitz-Araya X, Thomas RE, Low MJ, and Cone RD. Exocrine gland dysfunction in MC5-R-deficient mice: evidence for coordinated regulation of exocrine gland function by melanocortin peptides. Cell 91: 789-798, 1997.
    • (1997) Cell , vol.91 , pp. 789-798
    • Chen, W.1    Kelly, M.A.2    Opitz-Araya, X.3    Thomas, R.E.4    Low, M.J.5    Cone, R.D.6
  • 13
    • 0034629465 scopus 로고    scopus 로고
    • Agouti and agouti-related protein: Analogies and contrasts
    • Dinulescu DM and Cone RD. Agouti and agouti-related protein: analogies and contrasts. J Biol Chem 275: 6695-6698, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 6695-6698
    • Dinulescu, D.M.1    Cone, R.D.2
  • 15
    • 0028846891 scopus 로고
    • Mitogen-activated protein kinase pathway and AP-1 are activated during cAMP induced melanogenesis in B-16 melanoma cells
    • Englaro W, Rezzonico R, Durand-Clément M, Lallemand D, Ortonne J-P, and Ballotti R. Mitogen-activated protein kinase pathway and AP-1 are activated during cAMP induced melanogenesis in B-16 melanoma cells. J Biol Chem 270: 24315-24320, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 24315-24320
    • Englaro, W.1    Rezzonico, R.2    Durand-Clément, M.3    Lallemand, D.4    Ortonne, J.-P.5    Ballotti, R.6
  • 16
    • 0030614331 scopus 로고    scopus 로고
    • Role of melanocortinergic neurons in feeding and the agouti obesity syndrome
    • Fan W, Boston BA, Kesterson RA, Hruby VJ, and Cone RD. Role of melanocortinergic neurons in feeding and the agouti obesity syndrome. Nature 385: 165-168, 1997.
    • (1997) Nature , vol.385 , pp. 165-168
    • Fan, W.1    Boston, B.A.2    Kesterson, R.A.3    Hruby, V.J.4    Cone, R.D.5
  • 23
    • 0028795063 scopus 로고
    • Role of tyrosine kinase and protein kinase C in the steroidogenic actions of angiotensin II, alpha-melanocyte-stimulating hormone and corticotropin in the rat adrenal cortex
    • Kapas S, Purbrick A, and Hinson JP. Role of tyrosine kinase and protein kinase C in the steroidogenic actions of angiotensin II, alpha-melanocyte-stimulating hormone and corticotropin in the rat adrenal cortex. Biochem J 305: 433-438, 1995.
    • (1995) Biochem J , vol.305 , pp. 433-438
    • Kapas, S.1    Purbrick, A.2    Hinson, J.P.3
  • 24
    • 0021917536 scopus 로고
    • Role of calcium and cAMP in the action of adrenocorticotropin on aldosterone secretion
    • Kojima I, Kojima K, and Rasmussen H. Role of calcium and cAMP in the action of adrenocorticotropin on aldosterone secretion. J Biol Chem 260: 4248-4256, 1985.
    • (1985) J Biol Chem , vol.260 , pp. 4248-4256
    • Kojima, I.1    Kojima, K.2    Rasmussen, H.3
  • 25
    • 0028233234 scopus 로고
    • Interaction of dual intracellular signaling pathways activated by the melanocortin-3 receptor
    • Konda Y, Gantz I, DelValle J, Shimoto Y, Miwa H, and Yamada T. Interaction of dual intracellular signaling pathways activated by the melanocortin-3 receptor. J Biol Chem 269: 13162-13166, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 13162-13166
    • Konda, Y.1    Gantz, I.2    DelValle, J.3    Shimoto, Y.4    Miwa, H.5    Yamada, T.6
  • 26
    • 0031838353 scopus 로고    scopus 로고
    • Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans
    • Krude H, Biebermann H, Werner L, Horn R, Brabant G, and Grüters A. Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans. Nat Genet 19: 155-157, 1998.
    • (1998) Nat Genet , vol.19 , pp. 155-157
    • Krude, H.1    Biebermann, H.2    Werner, L.3    Horn, R.4    Brabant, G.5    Grüters, A.6
  • 27
    • 85047684373 scopus 로고    scopus 로고
    • Hypothalamic melanocortin signaling in cachexia
    • Lechan RM and Tatro JB. Hypothalamic melanocortin signaling in cachexia. Endocrinology 142: 3288-3291, 2001.
    • (2001) Endocrinology , vol.142 , pp. 3288-3291
    • Lechan, R.M.1    Tatro, J.B.2
  • 28
    • 0036443705 scopus 로고    scopus 로고
    • Chronic infusion of a melanocortin receptor agonist modulates dopamine receptor binding in the rat brain
    • Lindblom J, Kask A, Hagg E, Harmark L, Bergstrom L, and Wikberg J. Chronic infusion of a melanocortin receptor agonist modulates dopamine receptor binding in the rat brain. Pharmacol Res 45: 119-124, 2002.
    • (2002) Pharmacol Res , vol.45 , pp. 119-124
    • Lindblom, J.1    Kask, A.2    Hagg, E.3    Harmark, L.4    Bergstrom, L.5    Wikberg, J.6
  • 31
    • 0032787656 scopus 로고    scopus 로고
    • Role of epidermal cell-derived α-melanocyte stimulating hormone in ultraviolet light mediated local immunosuppresssion
    • Luger TA, Schwarz H, Scholzen KT, Schwarz A, and Brzoska T. Role of epidermal cell-derived α-melanocyte stimulating hormone in ultraviolet light mediated local immunosuppresssion. Ann NY Acad Sci 885: 209-216, 1999.
    • (1999) Ann NY Acad Sci , vol.885 , pp. 209-216
    • Luger, T.A.1    Schwarz, H.2    Scholzen, K.T.3    Schwarz, A.4    Brzoska, T.5
  • 32
    • 0035951058 scopus 로고    scopus 로고
    • High-resolution NMR structure of the chemically-synthesized melanocortin receptor binding domain AGRP(87-132) of the agouti-related protein
    • McNulty JC, Thompson DA, Bolin KA, Wilken J, Barsh GS, and Millhauser GL. High-resolution NMR structure of the chemically-synthesized melanocortin receptor binding domain AGRP(87-132) of the agouti-related protein. Biochemistry 40: 15520-15527, 2001.
    • (2001) Biochemistry , vol.40 , pp. 15520-15527
    • McNulty, J.C.1    Thompson, D.A.2    Bolin, K.A.3    Wilken, J.4    Barsh, G.S.5    Millhauser, G.L.6
  • 33
    • 0035130843 scopus 로고    scopus 로고
    • AGRP(87-132) acts as an inverse agonist on the human-melanocortin-4 receptor
    • Nijenhuis WA, Oosterom J, and Adan RAH. AGRP(87-132) acts as an inverse agonist on the human-melanocortin-4 receptor. Mol Endocrinol 15: 164-171, 2001.
    • (2001) Mol Endocrinol , vol.15 , pp. 164-171
    • Nijenhuis, W.A.1    Oosterom, J.2    Adan, R.A.H.3
  • 34
    • 0030764741 scopus 로고    scopus 로고
    • Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
    • Ollmann MM, Wilson BD, Yang Y-K, Kerns JA, Chen Y, Gantz I, and Barsh GS. Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein. Science 278: 135-138, 1997.
    • (1997) Science , vol.278 , pp. 135-138
    • Ollmann, M.M.1    Wilson, B.D.2    Yang, Y.-K.3    Kerns, J.A.4    Chen, Y.5    Gantz, I.6    Barsh, G.S.7
  • 35
    • 0036125112 scopus 로고    scopus 로고
    • Pro-opiomelanocortin processing in the hypothalamus: Impact on melanocortin signaling and obesity
    • Pritchard LE, Turnbull AV, and White A. Pro-opiomelanocortin processing in the hypothalamus: impact on melanocortin signaling and obesity. J Endocrinol 172: 411-421, 2002.
    • (2002) J Endocrinol , vol.172 , pp. 411-421
    • Pritchard, L.E.1    Turnbull, A.V.2    White, A.3
  • 39
    • 0035160974 scopus 로고    scopus 로고
    • The melanocortin-1 receptor: Red hair and beyond
    • Schaffer JV and Bolognia JL. The melanocortin-1 receptor: red hair and beyond. Arch Dermatol 137: 1477-1485, 2001.
    • (2001) Arch Dermatol , vol.137 , pp. 1477-1485
    • Schaffer, J.V.1    Bolognia, J.L.2
  • 41
    • 0032796447 scopus 로고    scopus 로고
    • α-MSH the regulation of melanocyte function
    • Thody AJ. α-MSH and the regulation of melanocyte function. Ann NY Acad Sci 885: 217-229, 1999.
    • (1999) Ann NY Acad Sci , vol.885 , pp. 217-229
    • Thody, A.J.1
  • 42
    • 0017084808 scopus 로고
    • Effect of α-melanocyte-stimulating hormone and testosterone on cutaneous and modified sebaceous glands in the rat
    • Thody AJ, Cooper MF, Bowden PE, Meddis D, and Shuster S. Effect of α-melanocyte-stimulating hormone and testosterone on cutaneous and modified sebaceous glands in the rat. J Endocrinol 71: 279-288, 1976.
    • (1976) J Endocrinol , vol.71 , pp. 279-288
    • Thody, A.J.1    Cooper, M.F.2    Bowden, P.E.3    Meddis, D.4    Shuster, S.5
  • 43
    • 0018366476 scopus 로고
    • Facilitation and inhibition of sexual receptivity in the female rat by α-MSH
    • Thody AJ, Wilson CA, and Everard D. Facilitation and inhibition of sexual receptivity in the female rat by α-MSH. Physiol Behav 22: 447-450, 1979.
    • (1979) Physiol Behav , vol.22 , pp. 447-450
    • Thody, A.J.1    Wilson, C.A.2    Everard, D.3
  • 44
    • 0027423948 scopus 로고
    • Hereditary isolated glucocorticoid deficiency is associated with abnormalities of the adrenocorticotropin receptor gene
    • Tsigo C, Arai K, Hung W, and Chrousos GP. Hereditary isolated glucocorticoid deficiency is associated with abnormalities of the adrenocorticotropin receptor gene. J Clin Invest 92: 2458-2461, 1993.
    • (1993) J Clin Invest , vol.92 , pp. 2458-2461
    • Tsigo, C.1    Arai, K.2    Hung, W.3    Chrousos, G.P.4
  • 45
    • 0033927916 scopus 로고    scopus 로고
    • Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity
    • Vaisse C, Clement K, Durand E, Hercberg S, Guy-Grand B, and Froguel P. Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity. J Clin Invest 106: 253-62, 2000.
    • (2000) J Clin Invest , vol.106 , pp. 253-262
    • Vaisse, C.1    Clement, K.2    Durand, E.3    Hercberg, S.4    Guy-Grand, B.5    Froguel, P.6
  • 46
    • 0028786945 scopus 로고
    • Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans
    • Valverde P, Healy E, Jackson I, Rees JL, and Thody AJ. Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans. Nat Genet 11: 328-330, 1995.
    • (1995) Nat Genet , vol.11 , pp. 328-330
    • Valverde, P.1    Healy, E.2    Jackson, I.3    Rees, J.L.4    Thody, A.J.5
  • 49
    • 0028291263 scopus 로고
    • Differences in dorsal and ventral pigmentation result from regional expression of the mouse agouti gene
    • Vrieling H, Duhl DM, Millar SE, Miller KA, and Barsh GS. Differences in dorsal and ventral pigmentation result from regional expression of the mouse agouti gene. Proc Natl Acad Sci USA 91: 5667-5671, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 5667-5671
    • Vrieling, H.1    Duhl, D.M.2    Millar, S.E.3    Miller, K.A.4    Barsh, G.S.5
  • 50
    • 0032323804 scopus 로고    scopus 로고
    • Synthetic melanotropic peptide initiates erections in men with psychogenic erectile dysfunction: Double-blind placebo controlled crossover study
    • Wessells H, Fuciarelli K, Hansen J, Hadley ME, Hruby VJ, Dorr R, and Levine N. Synthetic melanotropic peptide initiates erections in men with psychogenic erectile dysfunction: double-blind placebo controlled crossover study. J Urol 160: 389-393, 1998.
    • (1998) J Urol , vol.160 , pp. 389-393
    • Wessells, H.1    Fuciarelli, K.2    Hansen, J.3    Hadley, M.E.4    Hruby, V.J.5    Dorr, R.6    Levine, N.7
  • 51
    • 0033829159 scopus 로고    scopus 로고
    • Effect of an alpha-melanocyte stimulating hormone analog on penile erection and sexual desire in men with organic erectile dysfunction
    • Wessells H, Gralnek D, Dorr R, Hruby VJ, Hadley ME, and Levin N. Effect of an alpha-melanocyte stimulating hormone analog on penile erection and sexual desire in men with organic erectile dysfunction. Urology 56: 641-646, 2002.
    • (2002) Urology , vol.56 , pp. 641-646
    • Wessells, H.1    Gralnek, D.2    Dorr, R.3    Hruby, V.J.4    Hadley, M.E.5    Levin, N.6
  • 52
    • 0033011926 scopus 로고    scopus 로고
    • Melanocortin receptors: Perspectives for novel drugs
    • Wikberg JES. Melanocortin receptors: perspectives for novel drugs. Eur J Pharmacol 375: 295-310, 1999.
    • (1999) Eur J Pharmacol , vol.375 , pp. 295-310
    • Wikberg, J.E.S.1
  • 53
    • 0034456725 scopus 로고    scopus 로고
    • The role of the dorsal vagal complex and the vagus nerve in feeding effects of melanocortin-3/4 receptor stimulation
    • Williams DL, Kaplan JM, and Grill HJ. The role of the dorsal vagal complex and the vagus nerve in feeding effects of melanocortin-3/4 receptor stimulation. Endocrinology 141: 1332-1337, 2000.
    • (2000) Endocrinology , vol.141 , pp. 1332-1337
    • Williams, D.L.1    Kaplan, J.M.2    Grill, H.J.3


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