Ciliary neurotrophic factor corrects obesity and diabetes associated with leptin deficiency and resistance

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 12, 1997, Pages 6456-6461

  Gloaguen, Isabelle ^a   Costa, Patrizia ^a   Demartis, Anna ^a   Lazzaro, Domenico ^a   Di Marco, Annalise ^a   Graziani, Rita ^a   Paonessa, Giacomo ^a   Chen, Fang ^b   Rosenblum, Charles I ^b   Van Der Ploeg, Lex H T ^b   Cortese, Riccardo ^a   Ciliberto, Gennaro ^a   Laufer, Ralph ^a  

^a IRBM   (Italy)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANOREXIA; ARTICLE; BODY COMPOSITION; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE RESISTANCE; FOOD INTAKE; HOMEOSTASIS; HYPERPHAGIA; HYPOTHALAMUS; IN SITU HYBRIDIZATION; NEUROBLASTOMA; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ANIMALS; ARCUATE NUCLEUS; BLOOD GLUCOSE; BODY WEIGHT; BRAIN; CARRIER PROTEINS; CELL LINE; CILIARY NEUROTROPHIC FACTOR; DIABETES MELLITUS, TYPE 2; DIETARY FATS; DNA-BINDING PROTEINS; GROOMING; HUMANS; HYBRID CELLS; INSULIN; LEPTIN; MALE; MICE; MICE, INBRED AKR; MICE, INBRED C57BL; MICE, OBESE; MOTOR ACTIVITY; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEUROBLASTOMA; NEURONS; OBESITY; POINT MUTATION; PROTEINS; RECEPTOR, CILIARY NEUROTROPHIC FACTOR; RECEPTORS, CELL SURFACE; RECEPTORS, NERVE GROWTH FACTOR; RECOMBINANT PROTEINS;

ANIMALIA;

EID: 0345121142     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.12.6456     Document Type: Article

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