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Volumn 7, Issue 2, 2005, Pages 125-131

Transcriptional gene silencing by short interfering RNAs

Author keywords

DNA methylation; Double stranded RNA; Post transcriptional gene silencing; RNA interference; Short interfering RNA; Transcriptional gene silencing

Indexed keywords

DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3B; DOUBLE STRANDED RNA; HISTONE DEACETYLASE; HISTONE H3; RNA DIRECTED RNA POLYMERASE; SMALL INTERFERING RNA; UVOMORULIN;

EID: 17144369848     PISSN: 14648431     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (36)

References (54)
  • 1
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC: Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature (1998) 391(6669):806-811.
    • (1998) Nature , vol.391 , Issue.6669 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 2
    • 4644223259 scopus 로고    scopus 로고
    • Mechanisms of gene silencing by double-stranded RNA
    • Meister G, Tuschl T: Mechanisms of gene silencing by double-stranded RNA. Nature (2004) 431(7006):343-349.
    • (2004) Nature , vol.431 , Issue.7006 , pp. 343-349
    • Meister, G.1    Tuschl, T.2
  • 3
    • 4644350944 scopus 로고    scopus 로고
    • Unlocking the potential of the human genome with RNA interference
    • Hannon GJ, Rossi JJ: Unlocking the potential of the human genome with RNA interference. Nature (2004) 431 7006):371-378.
    • (2004) Nature , vol.431 , Issue.7006 , pp. 371-378
    • Hannon, G.J.1    Rossi, J.J.2
  • 4
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • Bernstein E, Caudy AA, Hammond SM, Hannon GJ: Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature (2001) 409(6818):363-366.
    • (2001) Nature , vol.409 , Issue.6818 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3    Hannon, G.J.4
  • 5
    • 0034737298 scopus 로고    scopus 로고
    • RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
    • Zamora PD, Tuschl T, Sharp PA, Bartel DP: RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell (2000) 101(1):25-33.
    • (2000) Cell , vol.101 , Issue.1 , pp. 25-33
    • Zamora, P.D.1    Tuschl, T.2    Sharp, P.A.3    Bartel, D.P.4
  • 6
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21- and 22-nucleotide RNAs
    • Elbashir SM, Lendeckel W, Tuschl T: RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev (2001) 15 2):188-200.
    • (2001) Genes Dev. , vol.15 , Issue.2 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 7
    • 0034673638 scopus 로고    scopus 로고
    • An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
    • Hammond SM, Bernstein E, Beach D, Hannon GJ: An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature (2000) 404(6775):293-296.
    • (2000) Nature , vol.404 , Issue.6775 , pp. 293-296
    • Hammond, S.M.1    Bernstein, E.2    Beach, D.3    Hannon, G.J.4
  • 8
    • 0035839109 scopus 로고    scopus 로고
    • Argonaute2, a link between genetic and biochemical analyses of RNAi
    • Hammond SM, Boettcher S, Caudy AA, Kobayashi R, Hannon GJ: Argonaute2, a link between genetic and biochemical analyses of RNAi. Science (2001) 293(5532):1146-1150.
    • (2001) Science , vol.293 , Issue.5532 , pp. 1146-1150
    • Hammond, S.M.1    Boettcher, S.2    Caudy, A.A.3    Kobayashi, R.4    Hannon, G.J.5
  • 9
  • 10
    • 0036074161 scopus 로고    scopus 로고
    • RNA interference in human cells is restricted to the cytoplasm
    • Zeng Y, Cullen BR: RNA interference in human cells is restricted to the cytoplasm. RNA (2002) 8(7):855-860.
    • (2002) RNA , vol.8 , Issue.7 , pp. 855-860
    • Zeng, Y.1    Cullen, B.R.2
  • 11
    • 0030996469 scopus 로고    scopus 로고
    • Role of the double-stranded RNA-activated protein kinase (PKR) in cell regulation
    • Williams BR: Role of the double-stranded RNA-activated protein kinase (PKR) in cell regulation. Biochem Soc Trans (1997) 25(2):509-513.
    • (1997) Biochem. Soc. Trans. , vol.25 , Issue.2 , pp. 509-513
    • Williams, B.R.1
  • 13
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T: Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature (2001) 411(6836):494-498.
    • (2001) Nature , vol.411 , Issue.6836 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 14
    • 4344594013 scopus 로고    scopus 로고
    • Recent applications of RNAi in mammalian systems
    • Scherer L, Rossi JJ: Recent applications of RNAi in mammalian systems. Curr Pharm Biotechnol (2004) 5 4):355-360.
    • (2004) Curr. Pharm. Biotechnol. , vol.5 , Issue.4 , pp. 355-360
    • Scherer, L.1    Rossi, J.J.2
  • 15
    • 3242656346 scopus 로고    scopus 로고
    • Silencing of disease-related genes by small interfering RNAs
    • Fuchs U, Damm-Welk C, Borkhardt A: Silencing of disease-related genes by small interfering RNAs. Curr Mol Med (2004) 4(5):507-517.
    • (2004) Curr. Mol. Med. , vol.4 , Issue.5 , pp. 507-517
    • Fuchs, U.1    Damm-Welk, C.2    Borkhardt, A.3
  • 16
    • 0035859046 scopus 로고    scopus 로고
    • Gene silencing as an adaptive defence against viruses
    • Waterhouse PM, Wang MB, Lough T: Gene silencing as an adaptive defence against viruses. Nature (2001) 411 6839):834-842.
    • (2001) Nature , vol.411 , Issue.6839 , pp. 834-842
    • Waterhouse, P.M.1    Wang, M.B.2    Lough, T.3
  • 17
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros V: The functions of animal microRNAs. Nature (2004) 431(7006):350-355.
    • (2004) Nature , vol.431 , Issue.7006 , pp. 350-355
    • Ambros, V.1
  • 18
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP: MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell (2004) 116(2):281-297.
    • (2004) Cell , vol.116 , Issue.2 , pp. 281-297
    • Bartel, D.P.1
  • 19
    • 1842603463 scopus 로고    scopus 로고
    • World of small RNAs: From ribozymes to siRNA and miRNA
    • Kawasaki H, Wadhwa R, Taira K: World of small RNAs: From ribozymes to siRNA and miRNA. Differentiation (2004) 72 2-3):58-64.
    • (2004) Differentiation , vol.72 , Issue.2-3 , pp. 58-64
    • Kawasaki, H.1    Wadhwa, R.2    Taira, K.3
  • 20
    • 0037144457 scopus 로고    scopus 로고
    • Cleavage of Scarecrow-like mRNA targets directed by a class of Arabidopsis miRNA
    • Llave C, Xie Z, Kasschau KD, Carrington JC: Cleavage of Scarecrow-like mRNA targets directed by a class of Arabidopsis miRNA. Science (2002) 297(5589):2053-2056.
    • (2002) Science , vol.297 , Issue.5589 , pp. 2053-2056
    • Llave, C.1    Xie, Z.2    Kasschau, K.D.3    Carrington, J.C.4
  • 21
    • 0037224921 scopus 로고    scopus 로고
    • A biochemical framework for RNA silencing in plants
    • Tang G, Reinhart BJ, Bartel DP, Zamore PD: A biochemical framework for RNA silencing in plants. Genes Dev (2003) 17 1):49-63.
    • (2003) Genes Dev. , vol.17 , Issue.1 , pp. 49-63
    • Tang, G.1    Reinhart, B.J.2    Bartel, D.P.3    Zamore, P.D.4
  • 22
    • 2142654329 scopus 로고    scopus 로고
    • MicroRNA-directed cleavage of HOXB8 mRNA
    • Yekta S, Shih IH, Bartel DP: MicroRNA-directed cleavage of HOXB8 mRNA. Science (2004) 304(5670):594-596.
    • (2004) Science , vol.304 , Issue.5670 , pp. 594-596
    • Yekta, S.1    Shih, I.H.2    Bartel, D.P.3
  • 24
    • 0042528729 scopus 로고    scopus 로고
    • Heterochromatin and epigenetic control of gene expression
    • Grewal SI, Moazed D: Heterochromatin and epigenetic control of gene expression. Science (2003) 301 5634):798-802.
    • (2003) Science , vol.301 , Issue.5634 , pp. 798-802
    • Grewal, S.I.1    Moazed, D.2
  • 25
    • 4344705410 scopus 로고    scopus 로고
    • Small interfering RNA-induced transcriptional gene silencing in human cells
    • Morris KV, Chan SW, Jacobsen SE, Looney DJ: Small interfering RNA-induced transcriptional gene silencing in human cells. Science (2004) 305(5688):1289-1292.
    • (2004) Science , vol.305 , Issue.5688 , pp. 1289-1292
    • Morris, K.V.1    Chan, S.W.2    Jacobsen, S.E.3    Looney, D.J.4
  • 26
    • 4544242851 scopus 로고    scopus 로고
    • Induction of DNA methylation and gene silencing by short interfering RNAs in human cells
    • Kawasaki H, Taira K: Induction of DNA methylation and gene silencing by short interfering RNAs in human cells. Nature (2004) 431(7005):211-217.
    • (2004) Nature , vol.431 , Issue.7005 , pp. 211-217
    • Kawasaki, H.1    Taira, K.2
  • 27
    • 0036591878 scopus 로고    scopus 로고
    • The many faces of histone lysine methylation
    • Lachner M, Jenuwein T: The many faces of histone lysine methylation. Curr Opin Cell Biol (2002) 14(3):286-298.
    • (2002) Curr. Opin. Cell Biol. , vol.14 , Issue.3 , pp. 286-298
    • Lachner, M.1    Jenuwein, T.2
  • 29
    • 0033900314 scopus 로고    scopus 로고
    • Transcriptional silencing in fission yeast
    • Grewal SI: Transcriptional silencing in fission yeast. J Cell Physiol (2000) 184(3):311-318.
    • (2000) J. Cell Physiol. , vol.184 , Issue.3 , pp. 311-318
    • Grewal, S.I.1
  • 31
    • 10644221797 scopus 로고    scopus 로고
    • RITS acts in cis to promote RNA interference-mediated transcriptional and post-transcriptional silencing
    • Noma K, Sugiyama T, Cam H, Verdel A, Zofall M, Jia S, Moazed D, Grewal SI: RITS acts in cis to promote RNA interference-mediated transcriptional and post-transcriptional silencing. Nat Genet (2004) 36(11):1174-1180.
    • (2004) Nat. Genet. , vol.36 , Issue.11 , pp. 1174-1180
    • Noma, K.1    Sugiyama, T.2    Cam, H.3    Verdel, A.4    Zofall, M.5    Jia, S.6    Moazed, D.7    Grewal, S.I.8
  • 32
    • 10944248935 scopus 로고    scopus 로고
    • Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs
    • Motamedi MR, Verdell A, Colmenares SU, Gerber SA, Gygi SP, Moazed D: Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs. Cell (2004) 119 6):789-802.
    • (2004) Cell , vol.119 , Issue.6 , pp. 789-802
    • Motamedi, M.R.1    Verdell, A.2    Colmenares, S.U.3    Gerber, S.A.4    Gygi, S.P.5    Moazed, D.6
  • 33
    • 0042831010 scopus 로고    scopus 로고
    • Hairpin RNAs and retrotransposon LTRs effect RNAi and chromatin-based gene silencing
    • Schramke V, Allshire R: Hairpin RNAs and retrotransposon LTRs effect RNAi and chromatin-based gene silencing. Science (2003) 301(5636):1069-1074.
    • (2003) Science , vol.301 , Issue.5636 , pp. 1069-1074
    • Schramke, V.1    Allshire, R.2
  • 34
    • 0037072661 scopus 로고    scopus 로고
    • Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi
    • Volpe TA, Kidner C, Hall IM, Tang G, Grewal SI, Martienssen RA: Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Science (2002) 297(5588):1833-1837.
    • (2002) Science , vol.297 , Issue.5588 , pp. 1833-1837
    • Volpe, T.A.1    Kidner, C.2    Hall, I.M.3    Tang, G.4    Grewal, S.I.5    Martienssen, R.A.6
  • 36
    • 0942279615 scopus 로고    scopus 로고
    • Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery
    • Pal-Bhadra M, Leibovitch BA, Gandhi SG, Rao M, Bhadra U, Birchler JA, Elgin SC: Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery. Science (2004) 303(5658):669-672.
    • (2004) Science , vol.303 , Issue.5658 , pp. 669-672
    • Pal-Bhadra, M.1    Leibovitch, B.A.2    Gandhi, S.G.3    Rao, M.4    Bhadra, U.5    Birchler, J.A.6    Elgin, S.C.7
  • 37
    • 0036184188 scopus 로고    scopus 로고
    • RNAi related mechanisms affect both transcriptional and posttranscriptional transgene silencing in Drosophila
    • Pal-Bhadra M, Bhadra U, Birchler JA: RNAi related mechanisms affect both transcriptional and posttranscriptional transgene silencing in Drosophila. Mol Cell (2002) 9 2):315-327.
    • (2002) Mol. Cell , vol.9 , Issue.2 , pp. 315-327
    • Pal-Bhadra, M.1    Bhadra, U.2    Birchler, J.A.3
  • 38
    • 1842816517 scopus 로고    scopus 로고
    • Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways
    • Lee YS, Nakahara K, Pham JW, Kim K, He Z, Sontheimer EJ, Carthew RW: Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell (2004) 117 1):69-81.
    • (2004) Cell , vol.117 , Issue.1 , pp. 69-81
    • Lee, Y.S.1    Nakahara, K.2    Pham, J.W.3    Kim, K.4    He, Z.5    Sontheimer, E.J.6    Carthew, R.W.7
  • 39
    • 0036509836 scopus 로고    scopus 로고
    • Higher-order structure in pericentric heterochromatin involves a distinct pattern of histone modification and an RNA component
    • Maison C, Bailly D, Peters AH, Quivy JP, Roche D, Taddei A, Lachner M, Jenuwein T, Almouzni G: Higher-order structure in pericentric heterochromatin involves a distinct pattern of histone modification and an RNA component. Nat Genet (2002) 30 3):329-334.
    • (2002) Nat. Genet. , vol.30 , Issue.3 , pp. 329-334
    • Maison, C.1    Bailly, D.2    Peters, A.H.3    Quivy, J.P.4    Roche, D.5    Taddei, A.6    Lachner, M.7    Jenuwein, T.8    Almouzni, G.9
  • 42
    • 0028031830 scopus 로고
    • RNA-directed de novo methylation of genomic sequences in plants
    • Wassenegger M, Heimes S, Riedel L, Sänger H: RNA-directed de novo methylation of genomic sequences in plants. Cell (1994) 76(3):567-576.
    • (1994) Cell , vol.76 , Issue.3 , pp. 567-576
    • Wassenegger, M.1    Heimes, S.2    Riedel, L.3    Sänger, H.4
  • 43
    • 0034596989 scopus 로고    scopus 로고
    • Transcriptional silencing and promoter methylation triggered by double-stranded RNA
    • Matte MF, Aufsatz W, van der Winden J, Matzke MA, Matzke AJ: Transcriptional silencing and promoter methylation triggered by double-stranded RNA. EMBO J (2000) 19(19):5194-5201.
    • (2000) EMBO J. , vol.19 , Issue.19 , pp. 5194-5201
    • Matte, M.F.1    Aufsatz, W.2    van der Winden, J.3    Matzke, M.A.4    Matzke, A.J.5
  • 44
    • 0033832174 scopus 로고    scopus 로고
    • RNA-directed DNA methylation
    • Wassenegger M: RNA-directed DNA methylation. Plant Mol Biol (2000) 43(2-3):203-220.
    • (2000) Plant Mol. Biol. , vol.43 , Issue.2-3 , pp. 203-220
    • Wassenegger, M.1
  • 46
    • 0035873992 scopus 로고    scopus 로고
    • RNA-directed transcriptional gene silencing in plants can be inherited independently of the RNA trigger and requires Met1 for maintenance
    • Jones L, Ratcliff F, Baulcombe DC: RNA-directed transcriptional gene silencing in plants can be inherited independently of the RNA trigger and requires Met1 for maintenance. Curr Biol (2001) 11(10):747-757.
    • (2001) Curr. Biol. , vol.11 , Issue.10 , pp. 747-757
    • Jones, L.1    Ratcliff, F.2    Baulcombe, D.C.3
  • 48
    • 0037121952 scopus 로고    scopus 로고
    • HDA6, a putative histone deacetylase needed to enhance DNA methylation induced by double-stranded RNA
    • Aufsatz W, Mette MF, van der Winden J, Matzke M, Matzke AJ: HDA6, a putative histone deacetylase needed to enhance DNA methylation induced by double-stranded RNA. EMBO J (2002) 21 24):6832-6841.
    • (2002) EMBO J. , vol.21 , Issue.24 , pp. 6832-6841
    • Aufsatz, W.1    Mette, M.F.2    van der Winden, J.3    Matzke, M.4    Matzke, A.J.5
  • 49
    • 0037009520 scopus 로고    scopus 로고
    • Two classes of short interfering RNA in RNA silencing
    • Hamilton A, Voinnet O, Chappell L, Baulcombe D: Two classes of short interfering RNA in RNA silencing. EMBO J (2002) 21(17):4671-4679.
    • (2002) EMBO J. , vol.21 , Issue.17 , pp. 4671-4679
    • Hamilton, A.1    Voinnet, O.2    Chappell, L.3    Baulcombe, D.4
  • 50
    • 0037474126 scopus 로고    scopus 로고
    • Argonaute4 control of locus-specific siRNA accumulation and DNA and histone methylation
    • Zilberman D, Cao X, Jacobsen SE: Argonaute4 control of locus-specific siRNA accumulation and DNA and histone methylation. Science (2003) 299(5607):716-719.
    • (2003) Science , vol.299 , Issue.5607 , pp. 716-719
    • Zilberman, D.1    Cao, X.2    Jacobsen, S.E.3
  • 51
    • 4243085624 scopus 로고    scopus 로고
    • Distinct mechanisms determine transposon inheritance and methylation via small interfering RNA and histone modification
    • Lippman Z, May B, Yordan C, Singer T, Martienssen R: Distinct mechanisms determine transposon inheritance and methylation via small interfering RNA and histone modification. PLoS Biol (2003) 1(3):E67.
    • (2003) PLoS Biol. , vol.1 , Issue.3
    • Lippman, Z.1    May, B.2    Yordan, C.3    Singer, T.4    Martienssen, R.5
  • 52
    • 0037592877 scopus 로고    scopus 로고
    • Insight into the mechanism of the peptide-based gene delivery system MPG: Implications for delivery of siRNA into mammalian cells
    • Simeoni F, Morris MC, Heitz F, Divita G: Insight into the mechanism of the peptide-based gene delivery system MPG: Implications for delivery of siRNA into mammalian cells. Nucleic Acids Res (2003) 31(11):2717-2724.
    • (2003) Nucleic Acids Res. , vol.31 , Issue.11 , pp. 2717-2724
    • Simeoni, F.1    Morris, M.C.2    Heitz, F.3    Divita, G.4
  • 53
    • 0035859046 scopus 로고    scopus 로고
    • Gene silencing as an adaptive defence against viruses
    • Waterhouse PM, Wang MB, Lough T: Gene silencing as an adaptive defence against viruses. Nature (2001) 411 6839):834-842.
    • (2001) Nature , vol.411 , Issue.6839 , pp. 834-842
    • Waterhouse, P.M.1    Wang, M.B.2    Lough, T.3


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