RNA-directed DNA methylation

Plant Molecular Biology

Volumn 43, Issue 2-3, 2000, Pages 203-220

  Wassenegger, M ^a  

^a FhG Molekulare Biotechnologie   (Germany)

Author keywords

5 methylcytosine; RNA directed DNA methylation; RNA directed RNA polymerase; RNA DNA hybrid; Viroids

Indexed keywords

ANTISENSE RNA; CYTOSINE; DNA METHYLATION; DNA RNA INTERACTION; DOUBLE STRANDED DNA; EUKARYOTIC CELL; GENE DELETION; GENE EXPRESSION REGULATION; SIGNAL TRANSDUCTION;

EUKARYOTA; MAMMALIA; VIROIDS;

EID: 0033832174     PISSN: 01674412     EISSN: None     Source Type: Journal    
DOI: 10.1023/a:1006479327881     Document Type: Article

References (102)

1. Double-stranded RNA specifically disrupts gene expression during planarian regeneration
2. Changes in T-DNA methylation and expression are associated with phenotypic variation and plant regeneration in a crown gall tumor line
3. Competition: A common motif for the imprinting mechanism
4. Methylation induced premeiotically in Ascobolus: Coextension with DNA repeat length and effect on transcription elongation
5. RNA as a target and an initiator of post-transcriptional gene silencing in transgenic plants
6. Ectopic pairing of homologous DNA and post-transcriptional gene silencing in transgenic plants
7. Cytosine methylation of repeated sequences in eukaryotes: The role of DNA pairing
8. Creation of genomic methylation patterns
9. Viral pathogenicity determinants are suppressors of transgene silencing in Nicotiana benthamiana
10. DNA methylation and the regulation of the globin gene expression
11. High sensitivity mapping of methylated cytosines
12. XIST RNA paints the inactive X chromosome at interphase: Evidence for a novel RNA involved in nuclear chromosome structure
13. Transgene silencing of the al-1 gene in vegetative cells of Neurospora is mediated by a cytoplasmic effector and does not depend on DNA-DNA interactions or DNA methylation
14. Interchromosomal transfer of epigenetic states in Ascobulus: Transfer of DNA methylation is mechanistically related to homologous recombination
15. Cytosine methylation at CG and CNG sites is not a prerequisite for the initiation of transcriptional gene silencing in plants, but is required for its maintenance
16. Expression of single copies of a strongly expressed 35S transgene can be silenced posttranscriptionally
17. Arabidopsis mutants impaired in cosuppression
18. DNA methylafion in plants
19. RNA-triggered gene silencing
20. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
21. A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands
22. Constitutive and light-induced DNase I hypersensitive sites in the rbcS genes of pea (Pisum sativum)
23. Histone acetylation in chromatin structure and transcription
24. Imaging of viroids in nuclei from tomato leaf tissue by in situ hybridization and confocal laser scanning
25. Position-effect variegation after 60 years
26. Methylation of coding region alone inhibits gene expression in plant protoplasts
27. Lack of reciprocal genomic imprinting of sense and antisense RNA of mouse insulin-like growth factor II receptor in the central nervous system
28. Posttranscriptional silencing of reporter transgenes in tobacco correlates with DNA methylation
29. Sequences throughout the basic β-1,3-glucanase mRNA coding region are targets for homology dependent post-transcriptional gene silencing
30. Taming of transposable elements by homology-dependent gene silencing
31. Genomic imprinting and cancer
32. De novo methylation and co-suppression induced by a cytoplasmically replicating plant RNA virus
33. Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
34. A novel imprinted gene, encoding a RING zinc-finger protein, and overlapping antisense transcript in the Prader-Willi syndrome critical region
35. Do unintended antisense transcripts contribute to sense cosuppression in plants?
36. The formation of DNA methylation patterns and the silencing of genes
37. DNA methylation directs a time-dependent repression of transcription initiation
38. Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway
39. Listening to the silent genes: Transgene silencing, gene regulation and pathogen control
40. Neuronal expression of neural nitric oxide synthase (nNOS) protein is suppressed by an antisense RNA transcribed from an NOS pseudogene
41. Genome intruder scanning and modulation systems and transgene silencing
42. Targeted mutagenesis of Tsix leads to nonrandom X inactivation
43. Tsix, a gene antisense to Xist at the X-inactivation centre
44. Loss of imprinting of a paternally expressed transcript, with antisense orientation to KvLQT1, occurs frequently in Beckwith-Wiedemann syndrome and is independent of insulin-like growth factor II imprinting
45. Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA
46. The mojo of methylation
47. Formation of a thermodynamically metastable structure containing hairpin II is critical for infectivity of potato spindle tuber viroid RNA
48. An inverted repeat triggers cytosine methylation of identical sequences in Arabidopsis
49. A gene essential for de novo methylation and development in ascobolus reveals a novel type of eukaryotic DNA methyltransferase structure
50. How and why do plants inactivate homologous (trans)genes?
51. Epigenetic silencing of plant transgenes as a consequence of diverse cellular defence responses
52. Position effects and epigenetic silencing of plant transgenes
53. Homology-dependent gene silencing in tmnsgenic plants: Epistatic silencing loci contain multiple copies of methylated transgenes
54. Bisulfite genomic sequencing-derived methylation profile of the Xist gene throughout early mouse development
55. Production of aberrant promoter transcripts contributes to methylation and silencing of unlinked homologous promoters in trans
56. RNA-mediated degradation and chalcone synthase A silencing in Petunia
57. Molecular cloning of antisense transcripts of the mouse Xist gene
58. Targeted disruption of gene function in Drosophila by RNA interference (RNA-i): A role for nautilus in embryonic somatic muscle formation
59. LIT1, an imprinted antisense RNA in the human KvLQT1 locus identified by screening for differentially expressed transcripts using monochromosomal hybrids
60. Double-stranded RNA as a mediator in sequence-specific genetic silencing and cosuppression
61. Multiple imprinted sense and antisense transcripts, differential methylation and tandem repeats in a putative imprinting control region upstream of mouse Igf2
62. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
63. MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex
64. Double-stranded RNA induces mRNA degradation in Trypanosoma brucei
65. Detection of cytosine methylation in the maize alcohol dehydrogenase gene by genomic sequencing
66. Evidence that random and imprinted Xist expression is controlled by preemptive methylation
67. Activation of systemic silencing by localised introduction of DNA
68. Systemic acquired silencing: Transgene-specific post-transcriptional silencing is transmitted by grafting from silenced stocks to non-silenced scions
69. Telomeric maintenance and gene repression: A common end?
70. Mechanisms of heritable gene repression during development of Drosophila
71. A DNA target of 30 bp is sufficient for RNA-directed DNA methylation
72. Heavy de novo methylation at symmetrical and non-symmetrical sites is a hallmark of RNA-directed DNA methylation
73. The frequency and degree of cosuppression by sense chalcone synthase transgenes are dependent on transgene promoter strength and are reduced by premature nonsense codons in the transgene coding sequence
74. Making sense or antisense?
75. Silencing speaks up
76. Chromatin-mediated transcriptional repression in yeast
77. An imprinted antisense RNA overlaps UBE3A and a second maternally expressed transcript
78. DNA methylation inhibits elongation but not initiation of transcription in Neurospora crassa
79. Sex in the '90s
80. Viroid replication
81. Isolation of a RNA-directed RNA polymerase-specific cDNA clone from tomato leaf-tissue mRNA
82. Involvement of DNA methylation in human carcinogenesis
83. Homology-dependent silencing of the SC3 gene in Schizophyllum commune
84. A maternally methylated CpG island in KvLQTI is associated with an antisense paternal transcript and loss of imprinting in Beckwith-Wiedemann syndrome
85. Stalling of DNA methyltransferase in chromosome stability and chromosome remodelling
86. Transgenic plant virus resistance mediated by untranslatable sense RNAs: Expression, regulation, and fate of nonessential RNAs
87. Post-transcriptional silencing of chalcone synthase in Petunia by inverted transgene repeats
88. Position-dependent methylation and transcriptional silencing of transgenes in inverted T-DNA repeats: Implications for post-transcriptional silencing of homologous host genes in plants
89. RNAi in C. elegans: Soaking in the genome sequence
90. Specific interference by ingested dsRNA
91. Post-transcriptional silencing of a neomycin phosphotransferase II transgene correlates with the accumulation of unproductive RNAs and with increased cytosine methylation of 3'-flanking regions
92. Identification of a general silencer for 19S and 35S promoters in a transgenic tobacco plant: 90 bp of homology in the promoter sequence are sufficient for trans-inactivation
93. Promoter-dependent trans-inactivation in transgenic tobacco plants: Kinetic aspects of gene silencing and gene reactivation
94. Inhibition of tobacco nitrite reductase activity by expression of antisense RNA
95. Systemic spread of sequence-specific transgene RNA degradation in plants is initiated by localized introduction of ectopic promoterless DNA
96. Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation
97. A model for RNA-mediated gene silencing in higher plants
98. Signalling in gene silencing
99. RNA-directed de novo methylation of genomic sequences in plants
100. Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA
101. Sinful repression
102. Imprinted expression of the Igf2r gene depends on an intronic CpG island