Reduction of hepatic glucose production as a therapeutic target in the treatment of diabetes

Current Drug Targets: Immune, Endocrine and Metabolic Disorders

Volumn 5, Issue 1, 2005, Pages 51-59

  Wu, Chaodong ^a   Okar, David A ^b   Kang, Johnthomas ^a   Lange, Alex J ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Diabetes; Gluconeogenesis; Glycogenesis; Glycogenolysis; Glycolysis; Hepatic glouse production; Insulin resistance; Liver

Indexed keywords

6 PHOSPHOFRUCTOKINASE; ENZYME INHIBITOR; FRUCTOSE BISPHOSPHATASE; GLUCOSE; GLYCOGEN; GLYCOGEN SYNTHASE KINASE; HYDROXYSTEROID DEHYDROGENASE; LENTIVIRUS VECTOR; MESSENGER RNA; PARVOVIRUS VECTOR; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR; RETROVIRUS VECTOR; VANADIC ACID;

DIABETES MELLITUS; DRUG TARGETING; DYSLIPIDEMIA; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TRANSPORT; GLUCOSE UTILIZATION; GLYCOGEN SYNTHESIS; GLYCOGENOLYSIS; GLYCOLYSIS; HUMAN; INSULIN DEFICIENCY; LIPID METABOLISM; LIVER FUNCTION; NONHUMAN; PATHOGENESIS; PROTEIN FUNCTION; PROTEIN TARGETING; REVIEW; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY;

ANIMALS; DIABETES MELLITUS; DRUG DELIVERY SYSTEMS; GLUCOSE; HUMANS; HYPOGLYCEMIC AGENTS; LIVER;

EID: 15444369236     PISSN: 15680088     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568008053174769     Document Type: Review

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