Discovery of a human liver glycogen phosphorylase inhibitor that lowers blood glucose in vivo

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 4, 1998, Pages 1776-1781

  Martin, William H ^a   Hoover, Dennis J ^a   Armento, Sandra J ^a   Stock, Ingrid A ^a   Mcpherson, R Kirk ^a   Danley, Dennis E ^a   Stevenson, Ralph W ^a   Barrett, Eugene J ^b   Treadway, Judith L ^a  

^a PFIZER INC   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; CP 91149; DRUG VEHICLE; ENZYME INHIBITOR; GLUCAGON; GLUCOSE; GLYCOGEN PHOSPHORYLASE; METHYLCELLULOSE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG TARGETING; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLYCOGEN LIVER LEVEL; GLYCOGEN SYNTHESIS; GLYCOGENOLYSIS; HUMAN; HUMAN CELL; LIVER CELL; LIVER METABOLISM; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL;

AMIDES; ANIMALS; BLOOD GLUCOSE; CAFFEINE; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; ENZYME INHIBITORS; HUMANS; INDOLES; LIVER; LIVER GLYCOGEN; MALE; MICE; MICE, OBESE; PHOSPHORYLASES; RATS; RECOMBINANT PROTEINS;

ANIMALIA;

EID: 0032539696     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.4.1776     Document Type: Article

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