LIS1 Association with Dynactin is Required for Nuclear Motility and Genomic Union in the Fertilized Mammalian Oocyte

Cell Motility and the Cytoskeleton

Volumn 56, Issue 4, 2003, Pages 245-251

  Payne, Christopher ^a,b   St John, Justin C ^c   Ramalho Santos, João ^b,d   Schatten, Gerald ^b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Fertilization; LIS1 inhibition; Microtubules, molecular motor; Nuclear movement

Indexed keywords

DYNACTIN; DYNEIN ADENOSINE TRIPHOSPHATASE; PROTEIN ANTIBODY; PROTEIN DERIVATIVE; PROTEIN LIS1; PROTEIN SUBUNIT; RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CATTLE; CELL MIGRATION; CELL MOTILITY; CELL NUCLEUS; COMPLEX FORMATION; CONTROLLED STUDY; FERTILIZATION; GENE EXPRESSION; GENE FUSION; GENETIC TRANSFECTION; GENOME; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; MAMMAL CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PRIORITY JOURNAL; PRONUCLEUS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHESUS MONKEY; RNA ANALYSIS; WESTERN BLOTTING; ZYGOTE;

1-ALKYL-2-ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; BASE SEQUENCE; BIOLOGICAL TRANSPORT; CATTLE; CELL NUCLEUS; CLONING, MOLECULAR; FERTILIZATION; HUMANS; MACACA MULATTA; MICROTUBULE-ASSOCIATED PROTEINS; MOLECULAR SEQUENCE DATA; OOCYTES; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, NUCLEIC ACID; ZYGOTE;

BOVINAE; MACACA MULATTA; MAMMALIA;

EID: 0344420336     PISSN: 08861544     EISSN: None     Source Type: Journal    
DOI: 10.1002/cm.10151     Document Type: Article

References (27)

1. Cahana A, Reiner O. 1999. LIS1 and platelet-activating factor acetylhydrolase (Ib) catalytic subunits, expression in the mouse oocyte and zygote. FEBS Lett 451:99-102.
2. Coquelle FM, Caspi M, Cordelieres FP, Dompierre JP, Dujardin DL, Koifman C, Martin P, Hoogenraad CC, Akhmanova A, Galjart N, De Mey JR, Reiner, O. 2002. LIS1, CLIP-170's key to the dynein/dynactin pathway. Mol Cell Biol 22:3089-3102.
3. Dawe AL, Caldwell KA, Harris PM, Morris NR, Caldwell GA. 2001. Evolutionarily conserved nuclear migration genes required for early embryonic development in Caenorhabditis elegans. Dev Genes Evol 211:434-441.
4. Dean B, Chang S, Stevens J, Thomas PE, King C. 2002. Isolation and characterization of a UDP-glucuronosyltransferase (UGT1A01) cloned from female rhesus monkey. Arch Biochem Biophys 402:289-295.
5. Dobyns WB, Reiner O, Carrozzo R, Ledbetter DH. 1993. Lissencephaly: a human brain malformation associated with deletion of the LIS1 gene located at chromosome 17p13. JAMA 270:2838-2842.
6. Faulkner NE, Dujardin DL, Tai CY, Vaughan KT, O'Connell CB, Wang Y, Vallee RB. 2000. A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function. Nat Cell Biol 2:784-791.
7. Geiser JR, Schott EJ, Kingsbury TJ, Cole NB, Totis LJ, Bhattacharyya G, He L, Hoyt MA. 1997. Saccharomyces cerevisiae genes required in the absence of the CIN8-encoded spindle motor act in functionally diverse mitotic pathways. Mol Biol Cell 8:1035-1050.
8. Harlow E, Lane D. 1988. Antibodies: a laboratory manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
9. Hewitson L, Takahashi D, Dominko T, Simerly C, Schatten G. 1998. Fertilization and embryo development to blastocysts by intracytoplasmic sperm injection in the rhesus monkey. Hum Reprod 13:2786-2790.
10. Hirotsune S, Fleck MW, Gambello MJ, Bix GJ, Chen A, Clark GD, Ledbetter DH, McBain CJ, Wynshaw-Boris A. 1998. Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality. Nat Genet 19:333-339.
11. Lo Nigro C, Chong CS, Smith AC, Dobyns WB, Carrozzo R, Ledbetter DH. 1997. Point mutations and an intragenic deletion in LIS1, the lissencephaly causative gene in isolated lissencephaly sequence and Miller-Dieker syndrome. Hum Mol Genet 6:157-164.
12. Memili E, First NL. 1999. Control of gene expression at the onset of bovine embryonic development. Biol Reprod 61:1198-1207.
13. Morris MC, Depollier J, Mery J, Heitz F, Divita G. 2001. A peptide carrier for the delivery of biologically active proteins into mammalian cells. Nat Biotech 19:1173-1176.
14. Navara CS, First NL, Schatten G. 1994. Microtubule organization in the cow during fertilization, polyspermy, parthenogenesis, and nuclear transfer: the role of the sperm aster. Dev Biol 162:29-40.
15. Payne C, Schatten G. 2003. Golgi dynamics during meiosis are distinct from mitosis and are coupled to endoplasmic reticulum dynamics until fertilization. Dev Biol 26: (in press).
16. Payne C, Rawe V, Ramalho-Santos J, Simerly C, Schatten G. 2003. Preferentially localized dynein and perinuclear dynactin associate with nuclear pore complex proteins to mediate genomic union during mammalian fertilization. J Cell Sci 116: (in press).
17. Pires-daSilva A, Nayernia K, Engel W, Torres M, Stoykova A, Chowdhury K, Gruss P. 2001. Mice deficient for spermatid perinuclear RNA-binding protein show neurologic, spermatogenic, and sperm morphological abnormalities. Dev Biol 233:319-328.
18. Reinsch S, Karsenti E. 1997. Movement of nuclei along microtubules in Xenopus egg extracts. Curr Biol 7:211-214.
19. Richter JD. 2001. Think globally, translate locally: what mitotic spindles and neuronal synapses have in common. Proc Natl Acad Sci USA 98:7069-7071.
20. Salina D, Bodoor K, Eckley DM, Schroer TA, Rattner JB, Burke B. 2002. Cytoplasmic dynein as a facilitator of nuclear envelope breakdown. Cell 108:97-107.
21. Sapir T, Elbaum M, Reiner O. 1997. Reduction of microtubule catastrophe events by LIS1, platelet-activating factor acetylhydrolase subunit. EMBO J 16:6977-6984.
22. Schatten G. 1994. The centrosome and its mode of inheritance: the reduction of the centrosome during gametogenesis and its restoration during fertilization. Dev Biol 165:299-335.
23. Smith DS, Niethammer M, Ayala R, Zhou Y, Gambello MJ, Wynshaw-Boris A, Tsai LH. 2000. Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1. Nat Cell Biol 2:767-775.
24. Swan A, Nguyen T, Suter B. 1999. Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning. Nat Cell Biol 1:444-449.
25. Tai CY, Dujardin DL, Faulkner NE, Vallee RB. 2002. Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function. J Cell Biol 156:959-968.
26. Xiang X, Morris NR. 1999. Hyphal tip growth and nuclear migration. Curr Opin Microbiol 2:636-640.
27. Xiang X, Osmani AH, Osmani SA, Xin M, Morris NR. 1995. NudF, a nuclear migration gene in Aspergillus nidulans, is similar to the human LIS-1 gene required for neuronal migration. Mol Biol Cell 6:297-310.