Left-right asymmetry and kinesin superfamily protein KIF3a: New insights in determination of laterality and mesoderm induction by KIF3A(-/-) mice analysis

Journal of Cell Biology

Volumn 145, Issue 4, 1999, Pages 825-836

  Takeda, Sen ^a   Yonekawa, Yoshiaki ^a   Tanaka, Yosuke ^a   Okada, Yasushi ^a   Nonaka, Shigenori ^a   Hirokawa, Nobutaka ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Gene targeting; kif3A; Kinesin; Left right asymmetry; Microtubule

Indexed keywords

KINESIN;

ARTICLE; EMBRYO; EMBRYO DEVELOPMENT; GENE TARGETING; INTRACELLULAR TRANSPORT; MESODERM; MICROTUBULE; MOUSE; NEURAL TUBE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BODY PATTERNING; EMBRYONIC INDUCTION; FLUORESCENT DYES; GENE TARGETING; HEDGEHOG PROTEINS; KINESIN; MESODERM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEIN BIOSYNTHESIS; RECOMBINATION, GENETIC; TRANS-ACTIVATORS;

ERINACEIDAE;

EID: 0033577894     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.145.4.825     Document Type: Article

References (49)

1. Aizawa, H., Y. Sekine, R. Takemura, Z. Zhang, M. Nangaku, and N. Hirokawa. 1992. Kinesin family in murine central nervous system. J. Cell Biol. 119: 1287-1296.
2. Beech, P.L., K. Pagh-Roehl, Y. Noda, N. Hirokawa, B. Burnside, and J.L. Rosenbaum. 1996. Localization of kinesin superfamily proteins to the connecting cilium of fish photoreceptors. J. Cell Sci. 109:889-897.
3. Boleti, H., E. Karsenti, and I. Vernos. 1996. Xklp2, a novel Xenopus centrosomal kinesin-like protein required for centrosome separation during mitosis. Cell. 84:49-59.
4. Chiang, C., Y. Litingtung, E. Lee, K.E. Young, J.L. Corden, H. Westphal, and P.A. Beachy. 1996. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature. 383:407-413.
5. Cole, D.G., S.W. Chinn, K.P. Wedaman, K. Hall, T. Vuong, and J.M. Scholey. 1993. Novel heterotrimeric kinesin-related protein purified from sea urchin eggs. Nature. 366:268-270.
6. Cole, D.G., D.R. Diener, A.L. Himelblau, P.L. Beech, J.C. Fuster, and I.L. Rosenbaum. 1998. Chlamydomonas kinesin-II-dependent intraflagellar transport (IFT): IFT particles contain proteins required for ciliary assembly in Caenorhabditis elegans sensory neurons. J. Cell Biol. 141:993-1008.
7. Conlon, R.A., and J. Rossant. 1992. Exogenous retinoic acid rapidly induces anterior ectopic expression of murine Hox-2 genes in vivo. Development. 116:357-368.
8. Conlon, F.L., C.V. Wright, and E.J. Robertson. 1995. Effects of the TWis mutation on notochord formation and mesodermal patterning. Mech. Devel. 49: 201-209.
9. Cooper, M.K., J.A. Porter, K.E. Young, and P.A. Beachy. 1998. Teratogen-mediated inhibition of target tissue response to Shh signaling. Science. 280: 1603-1607.
10. Ekker, S.C., A.R. Ungar, P. Greenstein, D.P. von Kessler, J.A. Porter, R.T. Moon, and P.A. Beachy. 1995. Patterning activities of vertebrate hedgehog proteins in the developing eye and brain. Curr. Biol. 55:944-955.
11. Fath, K.R., and D.R. Burgess. 1994. Membrane motility mediated by unconventional myosin. Curr. Opin. Cell Biol. 6:131-135.
12. Gibbons, B.H., D.J. Asai, W.J. Tang, T.S. Hays, and I.R. Gibbons. 1994. Phylogeny and expression of axonemal and cytoplasmic dynein genes in sea urchins. Mol. Biol. Cell. 5:57-70.
13. Gibbons, I.R. 1996. The role of dynein in microtubule-based motility. Cell Struct. Func. 21:331-342.
14. Grafstein, B., and D.S Forman. 1980. Intracellular transport in neurons. Physiol. Rev. 60:1167-1283.
15. Harada, A., K. Oguchi, S. Okabe, J. Kuno, S. Terada, T. Ohshima, R. Sato-Yoshitake, Y. Takei. T. Noda, and N. Hirokawa. 1994. Altered microtuhule organization in small-calibre axons of mice lacking tau protein. Nature. 369: 488-491.
16. Hirokawa, N. 1996. Organelle transport along microtubules - the role of KIFs. Trends Cell Biol. 6:135-141.
17. Hirokawa, N. 1998. Kinesin and dynein superfamily proteins and the mechanism of organelle transport. Science. 279:519-526.
18. Hogan, B., R. Beddington, F. Costantini, and E. Lacy. 1994. Manipulating the Mouse Embryo: A Laboratory Manual. 2nd edition. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York. 497 pp.
19. Jordan, T., I. Hanson, D. Zaletayev, S. Hodgson, J. Prosser, A. Seawright, N. Hastie, and Y. van Heyningen. 1992. The human PAX6 gene is mutated in two patients with aniridia. Nature Genet. 1:328-332.
20. Kaufman, M.H. 1995. The Atlas of Mouse Development. Academic Press. London. 525 pp.
21. Kondo, S., R. Sato-Yoshitake, Y. Noda, H. Aizawa, T. Nakata, Y. Matsura, and N. Hirokawa. 1994. KIF3A is a new microtubule-based anterograde motor in the nerve axon. J. Cell Biol. 125:1095-1107.
22. Kozminski, K.G., P.L. Beech, and J.L. Rosenbaum. 1995. The Chlamydomonas kinesin-like protein FLA10 is involved in motility associated with the flagellar membrane. J. Cell Biol. 131:1517-1527.
23. Lanske, B., A.C. Karaplis, K. Lee, A. Luz, A. Vortkamp, A. Pirro, M. Karperien, L.H.K. Defize, C. Ho, R.C. Mulligan, A.B. Abou-Samra, H. Juppner, G.V. Segre, and H.M. Kronenberg. 1996. PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growth. Science. 273:663-666.
24. Levin, M., R.L. Johnson, C.D. Stern, M. Kuehn, and C. Tabin. 1995. A molecular pathway determining left-right asymmetry in chick embryogenesis. Cell. 82:803-814.
25. Meno, C. Y. Ito, Y. Saijoh, Y. Matsuda, K. Tashiro, S. Kuhara, and H. Hamada. 1997. Two closely-related left-right asymmetrically expressed genes, lefty-1 and lefty-2: their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos. Genes Cells. 2:513-524.
26. Meno, C., A. Shimono, Y. Saijoh, K. Yashiro, K. Mochida, S. Ohishi, S. Noji, H. Kondoh, and H. Hamada. 1998. lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal. Cell. 94:287-297.
27. Mizuhira, V., and Y. Futaesaku. 1972. New fixation for biological membranes using tannic acids. Acta Histochem. Cytochem. 5:233-236.
28. Morris, R.L., and J.M. Scholey. 1997. Heterotrimeric kinesin-II is required for the assembly of motile 9+2 ciliary axonemes on sea urchin embryos. J. Cell Biol. 138:1009-1022.
29. Muresan, V., T. Abramson, A. Lyass, D. Winter, E. Porro, F. Hong, N.L. Chamberlin, and B.J. Schnapp. 1998. KIF3C and KIF3A form a novel neuronal heteromeric kinesin that associates with membrane vesicles. Mol. Biol. Cell. 9:637-652.
30. Nonaka, S., Y. Tanaka, Y. Okada, S. Takeda, A. Harada, Y. Kanai, M. Kido, and N. Hirokawa. 1998. Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein. Cell. 95:829-837.
31. Okada, Y., H. Yamazaki, Y. Sekine-Aizawa, and N. Hirokawa. 1995. The neuron-specific kinesin superfamily protein KIFIA is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors. Cell. 81: 769-780.
32. Rosenbaum, J.L., D.G. Cole, and D.R. Diener. 1999. Intraflagellar transport: the eyes have it. J. Cell Biol. 144:385-388.
33. Shakir, MA., T. Fukushige, H. Yasuda, J. Miwa, and S.S. Siddiqui. 1993. C. elegans osm-3 gene mediating osmotic avoidance behaviour encodes a kinesin-like protein. Neuroreport. 4:891-894.
34. Sulik, K., D.B. Dehart, T. Iangaki, J.L. Carson, T. Vrablic, K. Gesteland, and G.C. Schoenwolf. 1994. Morphogenesis of the murine node and notochordal plate. Dev. Dynamics. 201:260-278.
35. Supp, D.M., D.P. Witte, S.S. Potter, and M. Brueckner. 1997. Mutation of an axonemal dynein affects left-right asymmetry in inversus viscerum mice. Nature. 389:963-966.
36. Takeda, S., T. Funakoshi, and N. Hirokawa. 1995. Tubulin dynamics in neuronal axons of zebrafish embryos. Neuron. 14:1257-1264.
37. Tanaka, Y., Z. Zhang, and N. Hirokawa. 1995. Identification and molecular evolution of new dynein-like protein sequences in rat brain. J. Cell Sci. 108: 1883-1893.
38. Tanaka, Y., Y. Kanai, Y. Okada, S. Nonaka, S. Takeda, A. Harada, and N. Hirokawa. 1998. Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria. Cell. 93:1147-1158.
39. Umeda, A., T. Yoshida, K. Yamaguchi, M. Kanazawa, and C. Torikata. 1995. Immunohistochemical analysis of rat and human respiratory cilia with antidynein antibody: comparison between normal cilia and pathological cilia in primary ciliary dyskinesia. Virchows Arch. 427:401-406.
40. Vigh-Teichmann, I., B. Vigh, and A. Aros. 1980. Ciliated perikarya, "peptidergic" synapses and supraependymal structures in the guinea pig hypothalamus. Acta Biol. Acad. Sci. Hunga. 31:373-394.
41. Walther, Z., M. Vashishtha, and J.L. Hall. 1994. The Chlamydomonas FLA10 gene encodes a novel kinesin-homologous protein. J. Cell Biol. 126:175-188.
42. Wang, F.S., J.S. Wolenski, R.E. Cheney, M.S. Mooseker, and D.G. Jay. 1996. Function of myosin-V in filopodial extension of neuronal growth cones. Science. 273:660-663.
43. Willison, K. 1990. The mouse Brachyury gene and mesoderm formation. Trends Genet. 6:104-105.
44. Yagi, T., S. Nada, N. Watanahe, H. Tamemoto, N. Kohmura, Y. Ikawa, and S. Aizawa. 1993. A novel negative selection for homologous recombinants using diphteria toxin A fragment gene. Anal. Biochem. 214:77-86.
45. Yamazaki, H., T. Nakata, Y. Okada, and N. Hirokawa. 1995. KIF3A/B: a heterodimeric kinesin superfamily protein that works as a microtubule plus end-directed motor for membrane organelle transport. J. Cell Biol. 130: 1387-1399.
46. Yamazaki, H.,T. Nakata, Y. Okada, and N. Hirokawa. 1996. Cloning and characterization of KAP3: a novel kinesin superfamily-associated protein of KIF3A/3B. Proc. Natl. Acad. Sci. USA. 93:8443-8448.
47. r 140,000 intermediate chian of Chlamydomonus flagellar inner arm dynein is a WD-repeat protein implicated in dynein arm anchoring. Mol. Biol. Cell. 9:3335-3339.
48. Yang, Z., and L.S. Goldstein. 1998. Characterization of the KIF3C neural kinesin-like motor from mouse. Mol. Biol. Cell. 9:249-261.
49. Yoshida, T., K. Katsuta, H. Takanari, and K. Izutsu. 1989. Analysis of mammalian dynein using antibodies against A polypeptides of sea urchin sperm flagellar dynein. Exp. Cell Res. 184:440-448.