LIS1 and dynein motor function in neuronal migration and development

Genes and Development

Volumn 15, Issue 6, 2001, Pages 639-651

  Wynshaw Boris, A ^a   Gambello, M J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLECORTIN; DYNEIN ADENOSINE TRIPHOSPHATASE;

AGYRIA; ASPERGILLUS NIDULANS; CELL MIGRATION; CENTROSOME; HOMOZYGOSITY; HUMAN; LETHALITY; MOTOR PERFORMANCE; NERVE CELL DIFFERENTIATION; PRIORITY JOURNAL; REVIEW; SEQUENCE HOMOLOGY;

1-ALKYL-2-ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; ANIMALS; ASPERGILLUS NIDULANS; BRAIN DISEASES; CARRIER PROTEINS; CELL DIVISION; CELL MOVEMENT; CENTROSOME; CLONING, MOLECULAR; CYCLIN-DEPENDENT KINASE 5; CYCLIN-DEPENDENT KINASES; DYNEIN ATPASE; HUMANS; MICE; MICROTUBULE-ASSOCIATED PROTEINS; MODELS, BIOLOGICAL; MUTATION; NEURONS;

ASPERGILLUS; EMERICELLA NIDULANS;

EID: 0035868823     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.886801     Document Type: Review

References (88)

1. The spectrum of lissencephaly: Report of ten patients analyzed by magnetic resonance imaging
2. Microtubules and neuronal polarity: Lessons from mitosis
3. The "8-kD" cytoplasmic dynein light chain is required for nuclear migration and for dynein heavy chain localization in Aspergillus nidulans
4. Interaction between LIS1 and doublecortin, two lissencephaly gene products
5. Mechanism of cortical development: A review from mutations in mice
6. Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality
7. Deletion of nudC, a nuclear migration gene of Aspergillus nidulans, causes morphological and cell wall abnormalities and is lethal
8. A revision of the lissencephaly and Miller-Dieker syndrome critical regions in chromosome 17p13.3
9. Centractin is an actin homologue associated with the centrosome
10. Reeler: New tales on an old mutant mouse
11. A protein related to extracellular matrix proteins deleted in the mouse mutant reeler
12. Reelin is a secreted glycoprotein recognized by the CR-50 monoclonal antibody
13. Reelin is a ligand for lipoprotein receptors
14. α-spectrin is required for germline cell division and differentiation in the Drosophila ovary
15. A novel CNS gene required for neuronal migration and involved in X-linked subcortical laminar heterotopia and lissencephaly syndrome
16. Lissencephaly and other malformations of cortical development: 1995 update
17. Syndromes with lissencephaly. I. Miller-Dieker and Norman-Roberts syndromes and isolated lissencephaly
18. Causal heterogeneity in isolated lissencephaly
19. Frequent deletions of the LIS1 gene in classic lissencephaly
20. X-linked malformations of neuronal migration
21. Reelin binds α3β1-integrin and inhibits neuronal migration
22. The LIS1-related NUDF protein of Aspergillus nidulans interacts with the coiled-coil domain of the NUDE/RO11 protein
23. Glued participates in distinct microtubule-based activities in Drosophila eye development
24. A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function
25. LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome
26. Hippocampal abnormalities in Lis1 mutant mice provide a neuronal basis for epileptogenesis in neuronal migration defects
27. Doublecortin is a developmentally regulated, microtubule-associated protein expressed in migrating and differentiating neurons
28. Folding of proteins with WD-repeats: Comparison of six members of the WD-repeat superfamily to the G protein β subunit
29. Cyclin-dependent kinase 5-deficient mice demonstrate novel developmental arrest in cerebral cortex
30. A role for Abl in Notch signaling
31. Neuronal migration disorders: From genetic diseases to developmental mechanisms
32. Doublecortin, a brain-specific gene mutated in human X-linked lissencephaly and double cortex syndrome, encodes a putative signaling protein
33. Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons
34. Events governing organization of postmigratory neurons: Studies on brain development in normal and reeler mice
35. Characterization of KIFC2, a neuronal kinesin superfamily member in mouse
36. Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor acetylhydrolase
37. Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of the adapror protein Disabled-1 and modulates τ phosphorylation
38. The reeler gene encodes a protein with an EGF-like motif expressed by pioneer neurons
39. Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality
40. The role of the dynactin complex in intracellular motility
41. Doublecortin, a stabilizer of microtubules
42. Neuronal position in the developing brain is regulated by mouse disabled-1
43. Mouse disabled (mDab1): A Src binding protein implicated in neuronal development
44. Direct association of LIS1, the lissencephaly gene product, with a mammalian homologue of a fungal nuclear distribution protein, rNUDE
45. Mosaic analysis with a repressible neurotechnique cell marker for studies of gene function in neuronal morphogenesis
46. A vertebrate actin-related protein is a component of a multisubunit complex involved in microtubule-based vesicle motility
47. The Drosophila fusome, a germline-specific organelle, contains membrane skeletal proteins and functions in cyst formation
48. Lis1, the Drosophila homologue of a human lissencephaly disease gene, is required for germline cell division and oocyte differentiation
49. Drosophila Lis1 is required for neuroblast proliferation, dendritic elaboration and axonal transport
50. Point mutations and an intragenic deletion in LIS1, the lissencephaly causative gene in isolated lissencephaly sequence and Miller-Dieker syndrome
51. The microtubule motor cytoplasmic dynein is required for spindle orientation during germline cell divisions and oocyte differentiation in Drosophila
52. Regulation of cytoplasmic dynein function in vivo by the Drosophila Glued complex
53. Neurospora crassa ro-10 and ro-11 genes encode novel proteins required for nuclear distribution
54. Mitotic mutants of Aspergillus nidulans
55. Nuclear migration: From fungi to the mammalian brain
56. The ancient regulatory-protein family of WD-repeat proteins
57. NUDEL is a novel Cdk5 substrate that assocciates with LIS1 and cytoplasmic dynein
58. Nuclear movement is β-tubulin-dependent in Aspergillus nidulans
59. A β-tubulin mutation in Aspergillus nidulans that blocks microtubule function without blocking assembly
60. The reeler gene-associated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons
61. The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for antegrade axonal transport of synaptic vesicle precursor
62. Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death
63. The molecular cloning and identification of a gene product specifically required for nuclear movement in Aspergillus nidulans
64. Impaired learning and motor behavior in heterozygous Pafah1b1 (Lis1) mutant mice
65. LIS1 and XLIS (DCX) mutations cause most classical lissencephaly, but different patterns of malformation
66. Isolation of a Miller-Dieker lissencephaly gene containing G protein β-subunit-like repeats
67. Mutant mice with scrambled brains: Understanding the signaling pathways that control cell positioning in the CNS
68. A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult central nervous system
69. Reduction of microtubule catastrophe events by LIS1, platelet-activating factor acetylhydrolase subunit
70. Ultrastructural analysis of the dynactin complex: An actin-related protein is a component of a filament that resembles F-actin
71. New insights into the interaction of cytoplasmic dynein with the actin-related protein, Arp 1
72. Proteins of the CNR family are multiple receltors for Reelin
73. Homologs of the α- and β-subunits of mammalian brain platelet-activating factor acetylhydrolase Ib in the Drosophila melanogaster genome
74. Scramber and yotari disrupt the disabled gene and produce a reeler-like phenotype
75. Regulation of cytoplasmic dynein behavior and mirotubule organization by mammalian Lis1
76. Systematic identification of mitotic phoshoproteins
77. Drosophila Lissencephaly-1 functions with Bic-D and dynein in oocyte determination and nuclear positioning
78. Reeler/Disabled-like disruption of neuronal migration in kcockout mice lacking the VLDL receptor and ApoE receptor 2
79. Potential mechanisms of mutations that affect neuronal migration in man and mouse
80. Binding of pleckstrin homology domains to WD40/ β-transducin repeat containing segments of the protein product of the Lis-1 gene
81. Aberrant splicing of a mouse disabled homolog, mdab1, in the scrambler mouse
82. Mutations in the heavy chain of cytoplasmic dynein suppress the nudF nuclear migration mutation of Aspergillus nidulans
83. Hyphal tip growth and nuclear migration
84. Cytoplasmic dynein is involved in nuclear migration in Aspergillus nidulans
85. NudF, a nuclear migration gene in Aspergillus nidulans, is similar to the human LIS-1 gene required for neuronal migration
86. Isolation of a new set of Aspergillus nidulans mutants defective in nuclear migration
87. Hu-li tai shao, a gene required for ring canal formation during Drosophila oogenesis, encodes a homolog of adducin
88. Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth