Proteomic characterization of the human centrosome by protein correlation profiling

Nature

Volumn 426, Issue 6966, 2003, Pages 570-574

  Andersen, Jens S ^a   Wilkinson, Christopher J ^b   Mayor, Thibault ^b,c   Mortensen, Peter ^a   Nigg, Erich A ^b   Mann, Matthias ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^c CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; FRACTIONATION; MASS SPECTROMETRY; PROTEINS;

CELL PROFILERATION;

BIOCHEMISTRY;

BIOLOGY; PROTEIN;

ARTICLE; CELL CYCLE; CELL DIVISION; CELL MOTILITY; CELL POLARITY; CELL SHAPE; CENTROSOME; CHROMOSOME SEGREGATION; CONTROLLED STUDY; CYTOLOGY; CYTOSKELETON; HUMAN; HUMAN CELL; INTERPHASE; MASS SPECTROMETRY; MICROTUBULE ORGANIZING CENTER; MITOSIS SPINDLE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CORRELATION PROFILING; PROTEIN LOCALIZATION; PROTEOMICS;

AMINO ACID SEQUENCE; CELL LINE; CENTROSOME; CLONING, MOLECULAR; GENE EXPRESSION PROFILING; HUMANS; INTERPHASE; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PROTEINS; PROTEOMICS; SUBSTRATE SPECIFICITY;

ANIMALIA;

EID: 0346874342     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature02166     Document Type: Article

References (31)

1. Bornens, M. Centrosome composition and microtubule anchoring mechanisms. Curr. Opin. Cell Biol. 14, 25-34 (2002).
2. Doxsey, S. Re-evaluating centrosome function. Nature Rev. Mol. Cell Biol. 2, 688-698 (2001).
3. Nigg, E. A. Centrosome aberrations: cause or consequence of cancer progression? Nature Rev. Cancer 2, 815-825 (2002).
4. Nigg, E.A. Centrosome aberrations cause or consequence of cancer progression? Nature Rev. Cancer 2, 815-825 (2002).
5. Hinchcliffe, E. H. & Sluder, G. 'It takes two to tango': understanding how centrosome duplication is regulated throughout the cell cycle. Genes Dev. 15, 1167-1181 (2001).
6. Rieder, C. L., Faruki, S. & Khodjakov, A. The centrosome in vertebrates: more than a microtubule-organizing center. Trends Cell Biol. 11, 413-419 (2001).
7. Aebersold, R. & Mann, M. Mass spectrometry-based proteomics. Nature 422,198-207 (2003).
8. Wigge P. A. et al. Analysis of the Saccharomyces spindle pole by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. J. Cell Biol. 141, 967-977 (1998).
9. Bornens, M. & Moudjou, M. Studying the composition and function of centrosomes in vertebrates. Methods Cell Biol. 61, 13-34 (1999).
10. Kellogg, D. R., Moritz, M. & Alberts, B. M. The centrosome and cellular organization. Annu. Rev. Biochem. 63, 639-674 (1994).
11. Pietromonaco, S. F., Seluja, G. A., Aitken, A. & Elias, L. Association of 14-3-3 proteins with centrosomes. Blood Cells Mol. Dis. 22, 225-237 (1996).
12. Lange, B. M., Bachi, A., Wilm, M. & Gonzalez, C. Hsp90 is a core centrosomal component and is required at different stages of the centrosome cycle in Drosophila and vertebrates. EMBO J. 19, 1252-1262 (2000).
13. Brown, C. R., Doxsey, S. J., Hong-Brown, L. Q., Martin, R. L. & Welch, W. J. Molecular chaperones and the centrosome. A role for TCP-1 in microtubule nucleation. J. Biol. Chem. 271, 824-832 (1996).
14. Gergely, F. et al. The TACC domain identifies a family of centrosomal proteins that can interact with microlubules. Proc. Natl Acad. Sci. USA 97, 14352-14357 (2000).
15. Gascard, P. et al. Characterization of multiple isoforms of protein 4.1R expressed during erythroid terminal differentiation. Blood 92, 4404-4414 (1998).
16. Casenghi, M. et al. Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation. Dev. Cell 5, 113-125 (2003).
17. Chang, P. & Stearns, T. Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function. Nature Cell Biol. 2, 30-35 (2000).
18. Klotz, C. et al. Parthenogenesis in Xenopus eggs, requires centrosomal integrity. J. Cell Biol. 110, 405-415 (1990).
19. Nakagawa, Y., Yamane, Y., Okanoue, T. & Tsukila, S. Outer dense fiber 2 is a widespread centrosome scaffold component preferentially associated with mother centrioles: its identification from isolated centrosomes. Mol. Biol. Cell 12, 1687-1697 (2001).
20. Popovic, C. et al. The t(6;8)(q27;p11) translocation in a stein cell myeloproliferative disorder fuses a novel gene, FOP, to fibroblast growth factor receptor 1. Blood 93, 1381-1389 (1999).
21. Hearn, T. et al. Mutation of ALMS1, a large gene with a tandem repeat encoding 47 amino acids, causes Alström syndrome. Nature Genet. 31, 79-83 (2002).
22. Collin, G. B. et al. Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alström syndrome. Nature Genet. 31, 74-78 (2002).
23. Romio, L. et al. OFD1, the gene mutated in oral-facial-digital syndrome type 1, is expressed in the metanephros, and in human embryonic renal mesenchymal cells. J. Am. Soc. Nephrol. 14, 680-689 (2003).
24. Lamond, A. I. & Mann, M. Cell biology and the genome projects-a concerted strategy for characterizing multi-protein complexes using mass spectrometry. Trends Cell Biol. 7, 139-142 (1997).
25. Mayor, T., Stierhof, Y. D., Tanaka, K., Fry, A. M. & Nigg, E. A. The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion. J. Cell Biol. 151, 837-846 (2000).
26. Ohta, T. et al. Characterization of Cep 135, a novel coiled-coil centrosomal protein involved in microtubule organization in mammalian cells. J. Cell Biol. 156, 87-99 (2002).
27. Pfannenschmid, F. et al. Chlamydomonas DIP13 and human NA14: a new class of proteins associated with microtubule structures is involved in cell division. J. Cell Sci. 116, 1449-1462 (2003).
28. Kenedy, A. A., Cohen, K. J., Loveys, D. A., Kato, G. J. & Dang, C. V. Identification and characterization of the novel centrosome-associated protein CCCAP. Gene 303, 35-46 (2003).
29. Chen, Z., Indjeian, V. B., McManus, M., Wang, L. & Dynlacht, B. D. CP110, a cell cycle-dependent CDK substrate, regulates centrosome duplication in human cells. Dev. Cell 3, 339-350 (2002).
30. Yang, J. et al. Rootletin, a novel coiled-coil protein, is a structural component of the ciliary rootlet. J. Cell Biol. 159, 431-440 (2002).
31. Kilmartin, J. V. Sif1p has conserved centrin-binding sites and an essential function in building yeast spindle pole body duplication. J. Cell Biol. 162, 1211-1221 (2003).