Induction of cancer cell apoptosis by flavonoids is associated with their ability to inhibit fatty acid synthase activity

Journal of Biological Chemistry

Volumn 280, Issue 7, 2005, Pages 5636-5645

  Brusselmans, Koen ^a   Vrolix, Ruth ^a   Verhoeven, Guido ^a   Swinnen, Johannes V ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; ENZYME INHIBITION; ENZYMES; FATTY ACIDS; FOOD PRODUCTS; TOXICITY; TUMORS;

CANCER CELL APOPTOSIS; FLAVONOIDS; LIPOGENESIS; POLYPHENOLIC COMPOUNDS;

CELLS;

3 HYDROXYFLAVONE; APIGENIN; CATECHIN; EPICATECHIN; EPICATECHIN 3 GALLATE; EPICATECHIN GALLATE; EPIGALLOCATECHIN; EPIGALLOCATECHIN GALLATE; ERIODICTYOL; FATTY ACID SYNTHASE; FLAVONOID; GALANGIN; GENE PRODUCT; GENISTEIN; KAEMPFEROL; LUTEOLIN; MYRICETIN; NARINGENIN; PALMITIC ACID; POLYPHENOL DERIVATIVE; QUERCETIN; RESVERATROL; TAXIFOLIN; UNCLASSIFIED DRUG;

ADDITION REACTION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL; CANCER INHIBITION; CANCER PREVENTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; EXAMINATION; FATTY ACID SYNTHESIS; GENE INDUCTION; GENE REPRESSION; HUMAN; HUMAN CELL; LIPOGENESIS; OBSERVATION; PRIORITY JOURNAL; PROSTATE CANCER;

ANTIGENS, CD95; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SHAPE; CELL SURVIVAL; FATTY ACID SYNTHETASE COMPLEX; FIBROBLASTS; FLAVONOIDS; HUMANS; KAEMPFEROLS; LIPID METABOLISM; LIPIDS; LUTEOLIN; MOLECULAR STRUCTURE; NEOPLASMS; PALMITIC ACID; PHENOLS; QUERCETIN; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 14044267753     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M408177200     Document Type: Article

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