메뉴 건너뛰기




Volumn 58, Issue 20, 1998, Pages 4611-4615

Pharmacological inhibitors of mammalian fatty acid synthase suppress DNA replication and induce apoptosis in tumor cell lines

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; C 75; CERULETIDE; DNA; ENZYME INHIBITOR; FATTY ACID SYNTHASE; UNCLASSIFIED DRUG;

EID: 0032532655     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (237)

References (18)
  • 1
    • 0017137380 scopus 로고
    • The antibiotic cerulenin, a novel tool for biochemistry as an inhibitor of fatty acid synthesis
    • Omura, S. The antibiotic cerulenin, a novel tool for biochemistry as an inhibitor of fatty acid synthesis. Bacteriol. Rev., 40: 681-697, 1976.
    • (1976) Bacteriol. Rev. , vol.40 , pp. 681-697
    • Omura, S.1
  • 3
    • 0029971427 scopus 로고    scopus 로고
    • Inhibition of fatty acid synthesis delays disease progression in a xenograft model of ovarian cancer
    • Pizer, E. S., Wood, F. D., Heine, H. S., Romantsev, F. E., Pastemack, G. R., and Kuhajda, F. P. Inhibition of fatty acid synthesis delays disease progression in a xenograft model of ovarian cancer. Cancer Res., 56: 1189-1193, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 1189-1193
    • Pizer, E.S.1    Wood, F.D.2    Heine, H.S.3    Romantsev, F.E.4    Pastemack, G.R.5    Kuhajda, F.P.6
  • 5
    • 0029949512 scopus 로고    scopus 로고
    • Inhibition of fatty acid synthesis induces programmed cell death in human breast cancer cells
    • Pizer, E. S., Jackisch, C., Wood, F. D., Pasternack, G. R., Davidson, N. E., and Kuhajda, F. P. Inhibition of fatty acid synthesis induces programmed cell death in human breast cancer cells. Cancer Res., 56: 2745-2747, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 2745-2747
    • Pizer, E.S.1    Jackisch, C.2    Wood, F.D.3    Pasternack, G.R.4    Davidson, N.E.5    Kuhajda, F.P.6
  • 6
    • 0017343550 scopus 로고
    • Cerulenin-inhibited cells of Staphylococcus aureus resume growth when supplemented with either a saturated or an unsaturated fatty acid
    • Altenbern, R. Cerulenin-inhibited cells of Staphylococcus aureus resume growth when supplemented with either a saturated or an unsaturated fatty acid. Antimicrob. Agents Chemother., 11: 574-576, 1977.
    • (1977) Antimicrob. Agents Chemother. , vol.11 , pp. 574-576
    • Altenbern, R.1
  • 7
    • 0026656853 scopus 로고
    • Wild-type p53 is a cell cycle checkpoint determinant following irradiation
    • Kuerbitz, S. J., Plunkett, B. S., Walsh, W. V., and Kastan, M. B. Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proc. Natl. Acad. Sci. USA, 89: 7491-7495, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7491-7495
    • Kuerbitz, S.J.1    Plunkett, B.S.2    Walsh, W.V.3    Kastan, M.B.4
  • 9
    • 0030038191 scopus 로고    scopus 로고
    • Fatty acid synthase (FAS): A target for cytotoxic antimetabolites in HL60 promyelocytic leukemia cells
    • Pizer, E. S., Wood, F. D., Pasternack, G. R., and Kuhajda, F. P. Fatty acid synthase (FAS): a target for cytotoxic antimetabolites in HL60 promyelocytic leukemia cells. Cancer Res., 56: 745-751, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 745-751
    • Pizer, E.S.1    Wood, F.D.2    Pasternack, G.R.3    Kuhajda, F.P.4
  • 10
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipids from animal tissues
    • Folch, J., Lees, M., and Sloane Stanley, G. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem., 226: 497-509, 1957.
    • (1957) J. Biol. Chem. , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.3
  • 11
    • 0027269557 scopus 로고
    • Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays
    • Gorczyca, W., Gong, J., and Darzynkiewicz, Z. Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays. Cancer Res., 53: 1945-1951, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 1945-1951
    • Gorczyca, W.1    Gong, J.2    Darzynkiewicz, Z.3
  • 12
    • 0028274792 scopus 로고
    • Decreased membrane phospholipid packing and decreased cell size precede DNA cleavage in mature mouse B cell apoptosis
    • Mower, D. A., Jr., Peckham, D. W., Illera, V. A., Fishbaugh, J. K., Stunz, L. L., and Ashman, R. F. Decreased membrane phospholipid packing and decreased cell size precede DNA cleavage in mature mouse B cell apoptosis. J. Immunol., 152: 4832-4842, 1994.
    • (1994) J. Immunol. , vol.152 , pp. 4832-4842
    • Mower Jr., D.A.1    Peckham, D.W.2    Illera, V.A.3    Fishbaugh, J.K.4    Stunz, L.L.5    Ashman, R.F.6
  • 13
    • 0032147199 scopus 로고    scopus 로고
    • Fatty acid synthase expression in endometrial carcinoma: Correlation with cell proliferation and hormone receptors
    • Phila.
    • Pizer, E., Lax, S., Kuhajda, F., Pasternack, G., and Kurman, R. Fatty acid synthase expression in endometrial carcinoma: correlation with cell proliferation and hormone receptors. Cancer (Phila.), 83: 528-537, 1998.
    • (1998) Cancer , vol.83 , pp. 528-537
    • Pizer, E.1    Lax, S.2    Kuhajda, F.3    Pasternack, G.4    Kurman, R.5
  • 14
    • 0028828204 scopus 로고
    • Cyclins and cyclin-dependent kinases: Theme and variations
    • Pines, J. Cyclins and cyclin-dependent kinases: theme and variations. Adv. Cancer Res., 66: 181-212, 1995.
    • (1995) Adv. Cancer Res. , vol.66 , pp. 181-212
    • Pines, J.1
  • 15
    • 0030015029 scopus 로고    scopus 로고
    • How viral oncogenes make the cell cycle
    • Jansen-Durr, P. How viral oncogenes make the cell cycle. Trends Genet., 12: 270-275, 1996.
    • (1996) Trends Genet. , vol.12 , pp. 270-275
    • Jansen-Durr, P.1
  • 16
    • 0019351935 scopus 로고
    • SV40-transformed simian cells support the replicalion of early SV40 mutants
    • Gluzman, Y. SV40-transformed simian cells support the replicalion of early SV40 mutants. Cell, 23: 175-182, 1981.
    • (1981) Cell , vol.23 , pp. 175-182
    • Gluzman, Y.1
  • 17
    • 0027483921 scopus 로고
    • spoT-dependent accumulation of guanosine tetraphosphate in response to fatty acid starvation in Escherichia coli
    • Seyfzadeh, M., Kenner, J., and Nomura, M. spoT-dependent accumulation of guanosine tetraphosphate in response to fatty acid starvation in Escherichia coli. Proc. Natl. Acad. Sci. USA, 90: 11004-11008, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11004-11008
    • Seyfzadeh, M.1    Kenner, J.2    Nomura, M.3
  • 18
    • 0016192333 scopus 로고
    • Metabolic consequences of limited phospholipid synthesis in Escherichia coli
    • Pizer, L., Merlie, J., and Ponce de Leon, M. Metabolic consequences of limited phospholipid synthesis in Escherichia coli. J. Biol. Chem., 294: 3212-3224, 1974.
    • (1974) J. Biol. Chem. , vol.294 , pp. 3212-3224
    • Pizer, L.1    Merlie, J.2    De Ponce Leon, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.