Replicative senescence in sheep fibroblasts is a p53 dependent process

Experimental Gerontology

Volumn 40, Issue 1-2, 2005, Pages 17-26

  Davis, Terence ^a   Skinner, Julia W ^a   Faragher, Richard G A ^b   Jones, Christopher J ^a   Kipling, David ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF BRIGHTON   (United Kingdom)

Author keywords

Ageing; Animal models; Cellular immortalisation; p21WAF1; Proliferative lifespan barriers; Telomerase

Indexed keywords

PROTEIN P21; PROTEIN P53; SMALL INTERFERING RNA; TELOMERASE;

AGING; ANIMAL CELL; ARTICLE; CANCER; CELL CULTURE; CELL CYCLE; CELL DIVISION; CELL GROWTH; CELL IMMORTALIZATION; CELL POPULATION; CONTROLLED STUDY; ENZYME ACTIVITY; FIBROBLAST; IN VITRO STUDY; LIFESPAN; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; SENESCENCE; SHEEP; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; TELOMERE;

ANIMALS; CELL AGING; CELL CYCLE PROTEINS; CELL DIVISION; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; FIBROBLASTS; MODELS, ANIMAL; RNA, SMALL INTERFERING; SHEEP; TELOMERASE; TELOMERE; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA; OVIS ARIES;

EID: 12344254916     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2004.09.004     Document Type: Article

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