-
1
-
-
0027331491
-
Investigation of the Role of G1/S cell cycle mediators in cellular senescence
-
AFSHARI, C.A., VOJTA, P.J., ANNAB, L.A., FUTREAL, P.A., WILLARD, T.B., and BARRETT, C.J. Investigation of the Role of G1/S cell cycle mediators in cellular senescence. Exp. Cell Res. 209, 231-237, 1993.
-
(1993)
Exp. Cell Res.
, vol.209
, pp. 231-237
-
-
Afshari, C.A.1
Vojta, P.J.2
Annab, L.A.3
Futreal, P.A.4
Willard, T.B.5
Barrett, C.J.6
-
2
-
-
0026460896
-
Telomere length predicts the replicative capacity in human fibroblasts
-
ALLSOPP, R.C., VAZIRI, H., PATTERSON, C., GOLDSTEIN, S., YOUNGLAI, E.V., FUTCHER, A.B., GREIDER, C.W., and HARLEY, C.B. Telomere length predicts the replicative capacity in human fibroblasts. Proc. Natl. Acad. Sci. USA 89, 10114-10118, 1992.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10114-10118
-
-
Allsopp, R.C.1
Vaziri, H.2
Patterson, C.3
Goldstein, S.4
Younglai, E.V.5
Futcher, A.B.6
Greider, C.W.7
Harley, C.B.8
-
4
-
-
0029111404
-
-
ATADJA, P., WONG, H., GARKAVSTEV, I., VEILLETTE, C., and RIABOWOL, K. Proc. Natl. Acad. Sci. USA 92, 8348-8352, 1995.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 8348-8352
-
-
Atadja, P.1
Wong, H.2
Garkavstev, I.3
Veillette, C.4
Riabowol, K.5
-
5
-
-
0017166058
-
Specific chromosome alterations in senescent fibroblast cell lines derived from human embryos
-
BENN, P. Specific chromosome alterations in senescent fibroblast cell lines derived from human embryos. Am. J. Hum. Genet. 28, 465-473, 1976.
-
(1976)
Am. J. Hum. Genet.
, vol.28
, pp. 465-473
-
-
Benn, P.1
-
6
-
-
0025650332
-
Spontaneous abnormalities in normal fibroblasts from patients with Li-Fraumeni syndrome: Aneuploidy and immortalization
-
BISCHOFF, F.Z., YIM, S.O., PATHAK, S., GRANT, G., SICILIANO, M.J., GIOVANELLA, B.C., STRONG, L.C., and TAINSKY, M.A. Spontaneous abnormalities in normal fibroblasts from patients with Li-Fraumeni syndrome: Aneuploidy and immortalization. Cancer Res. 50, 7979-7984, 1990.
-
(1990)
Cancer Res.
, vol.50
, pp. 7979-7984
-
-
Bischoff, F.Z.1
Yim, S.O.2
Pathak, S.3
Grant, G.4
Siciliano, M.J.5
Giovanella, B.C.6
Strong, L.C.7
Tainsky, M.A.8
-
7
-
-
0025731583
-
The structure and function of telomeres
-
BLACKBURN, E.H. The structure and function of telomeres. Nature 350, 569-573, 1991.
-
(1991)
Nature
, vol.350
, pp. 569-573
-
-
Blackburn, E.H.1
-
8
-
-
0026523228
-
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
-
COUNTER, C.M., AVILION, A.A., LE FEUVRE, C.E., STEWART, N.G., GREIDER, C.W., HARLEY, C.B., and BACCHETTI, S. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J. 11, 1921-1929, 1992.
-
(1992)
EMBO J.
, vol.11
, pp. 1921-1929
-
-
Counter, C.M.1
Avilion, A.A.2
Le Feuvre, C.E.3
Stewart, N.G.4
Greider, C.W.5
Harley, C.B.6
Bacchetti, S.7
-
9
-
-
0028262113
-
Telomerase activity in human ovarian carcinoma
-
COUNTER, C.M., HIRTE, H., BACCHETTI, S., and HARLEY, C.B. Telomerase activity in human ovarian carcinoma. Proc. Natl. Acad. Sci. USA 91, 2900-2904, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 2900-2904
-
-
Counter, C.M.1
Hirte, H.2
Bacchetti, S.3
Harley, C.B.4
-
10
-
-
0027970713
-
DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblast
-
Di LEONARDO, A.I., LINKE, S.P., CLARKIN, K., and WAHL, G.M. DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblast. Genes Dev. 8, 2540-2551, 1994.
-
(1994)
Genes Dev.
, vol.8
, pp. 2540-2551
-
-
Di Leonardo, A.I.1
Linke, S.P.2
Clarkin, K.3
Wahl, G.M.4
-
11
-
-
0028220204
-
p53 dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during irradiation-induced G1 arrest
-
DULIC, V., KAUFMANN, W.K., WILSON, S.J., TLSTY, T.D., LEES, E., HARPER, J.W., ELLEDGE, S.J., and REED, S.I. p53 dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during irradiation-induced G1 arrest. Cell 76, 1013-1023, 1994.
-
(1994)
Cell
, vol.76
, pp. 1013-1023
-
-
Dulic, V.1
Kaufmann, W.K.2
Wilson, S.J.3
Tlsty, T.D.4
Lees, E.5
Harper, J.W.6
Elledge, S.J.7
Reed, S.I.8
-
12
-
-
0027359827
-
WAF1, a potent mediator of p53 tumor suppression
-
EL-DEIRY, W.S., TOKINO, T., VELCULESCU, V.E., LEVY, D.B., PARSONS, R., TRENT, J.M., LIN, D., MERCER, E., KINZLER, K.W., and VOGELSTEIN, B. WAF1, a potent mediator of p53 tumor suppression. Cell 75, 817-825, 1993.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, E.8
Kinzler, K.W.9
Vogelstein, B.10
-
13
-
-
0025145238
-
Replicative senescence: The human fibroblast comes of age
-
GOLDSTEIN, S. Replicative senescence: The human fibroblast comes of age. Science 249, 1129-1133, 1991.
-
(1991)
Science
, vol.249
, pp. 1129-1133
-
-
Goldstein, S.1
-
14
-
-
0025946601
-
Insulin-like growth factor binding protein 3 accumulates to high levels in culture medium of secescent and quiescent human fibroblasts
-
GOLDSTEIN, S., MOERMAN, E.J., JONES, R.A. and BAXTER, R.C. Insulin-like growth factor binding protein 3 accumulates to high levels in culture medium of secescent and quiescent human fibroblasts. Proc. Natl. Acad. Sci. U.S.A. 88, 9680-9684, 1991.
-
(1991)
Proc. Natl. Acad. Sci. U.S.A.
, vol.88
, pp. 9680-9684
-
-
Goldstein, S.1
Moerman, E.J.2
Jones, R.A.3
Baxter, R.C.4
-
15
-
-
0025201982
-
Position effect at S. Cerevisiae telomeres: Reversible repression of Pol II transcription
-
GOTTSCHLING, D.E., APARICIO, O.M., BILLINGTON, B.L., and ZAKIAN, V.A. Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription. Cell 63, 751-762, 1990.
-
(1990)
Cell
, vol.63
, pp. 751-762
-
-
Gottschling, D.E.1
Aparicio, O.M.2
Billington, B.L.3
Zakian, V.A.4
-
16
-
-
0022402513
-
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
-
GREIDER, C.W. and BLACKBURN, E.H. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 43, 405-414, 1985.
-
(1985)
Cell
, vol.43
, pp. 405-414
-
-
Greider, C.W.1
Blackburn, E.H.2
-
17
-
-
0025279931
-
Telomeres shorten during aging of human fibroblasts
-
HARLEY, C.B., FUTCHER, A.B., and GREIDER, C.W. Telomeres shorten during aging of human fibroblasts. Nature 345, 458-460, 1990.
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
18
-
-
0025787643
-
Telomere loss: Mitotic clock or genetic time bomb?
-
HARLEY, C.B. Telomere loss: Mitotic clock or genetic time bomb? Mutat. Res. 256, 271-282, 1991.
-
(1991)
Mutat. Res.
, vol.256
, pp. 271-282
-
-
Harley, C.B.1
-
19
-
-
0025143252
-
Telomere reduction in human colorectal carcinoma and with aging
-
HASTIE, N.D., DEMPSTER, M., DUNLOP, M.G., THOMPSON, A.M., GREEN, D.K., and ALLSHIRE, R.C. Telomere reduction in human colorectal carcinoma and with aging. Nature 346, 866-868, 1990.
-
(1990)
Nature
, vol.346
, pp. 866-868
-
-
Hastie, N.D.1
Dempster, M.2
Dunlop, M.G.3
Thompson, A.M.4
Green, D.K.5
Allshire, R.C.6
-
20
-
-
0027496935
-
The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
-
HARPER, J.W., ADAMI, G.R., WEI, N., KEYOMARSI, K., and ELLEDGE, S. The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75, 805-816, 1993.
-
(1993)
Cell
, vol.75
, pp. 805-816
-
-
Harper, J.W.1
Adami, G.R.2
Wei, N.3
Keyomarsi, K.4
Elledge, S.5
-
21
-
-
0344622606
-
The serial cultivation of human diploid strains
-
HAYFLICK, L. and MOORHEAD, P. The serial cultivation of human diploid strains. Exp. Cell Res. 25, 585-621, 1961.
-
(1961)
Exp. Cell Res.
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorhead, P.2
-
22
-
-
0027938209
-
Cyclins and Cancer II: Cyclin D and CDK inhibitors come of age
-
HUNTER, T. and PINES, J. Cyclins and Cancer II: Cyclin D and CDK inhibitors come of age. Cell 79, 573-582, 1994.
-
(1994)
Cell
, vol.79
, pp. 573-582
-
-
Hunter, T.1
Pines, J.2
-
23
-
-
0026496885
-
A mammalian cell cycle checkpoint pathway utilizing p53 and Gadd45 is defective in Ataxia-telangiectasia
-
KASTAN, M.B., ZHAN, Q., EL-DEIRY, W.S., CARRIER, F., JACKS T., WALSH, W.V., PLUNKETT, B.S., VOGELSTEIN, B., and FORNACE, A.J., JR. A mammalian cell cycle checkpoint pathway utilizing p53 and Gadd45 is defective in Ataxia-telangiectasia. Cell 71, 587-597, 1992.
-
(1992)
Cell
, vol.71
, pp. 587-597
-
-
Kastan, M.B.1
Zhan, Q.2
El-Deiry, W.S.3
Carrier, F.4
Jacks, T.5
Walsh, W.V.6
Plunkett, B.S.7
Vogelstein, B.8
Fornace A.J., Jr.9
-
24
-
-
0028564951
-
Specific association of telomerase with immortal cells and cancer
-
KIM, N.W., PLATYSZEK, M.A., PROWSE, K.R., HARLEY, C.B., WEST, M.D., HO, P.L., COVIELLO, G.M., WRIGHT, W.E., WEINRICH, S.L., and SHAY, J.W. Specific association of telomerase with immortal cells and cancer. Science 266, 2011-2014, 1994.
-
(1994)
Science
, vol.266
, pp. 2011-2014
-
-
Kim, N.W.1
Platyszek, M.A.2
Prowse, K.R.3
Harley, C.B.4
West, M.D.5
Ho, P.L.6
Coviello, G.M.7
Wright, W.E.8
Weinrich, S.L.9
Shay, J.W.10
-
25
-
-
0026735646
-
Telomere end-replication problem and cell senescence
-
LEVY, M.L., ALLSOPP, R.C., FUTCHER, A.B., GREIDER, C.W., and HARLEY, C.B. Telomere end-replication problem and cell senescence. J. Mol. Biol. 225, 951-960. 1992.
-
(1992)
J. Mol. Biol.
, vol.225
, pp. 951-960
-
-
Levy, M.L.1
Allsopp, R.C.2
Futcher, A.B.3
Greider, C.W.4
Harley, C.B.5
-
26
-
-
0026801062
-
Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
-
LIVINGSTONE, L.R., WHITE, A., SPROUSE, J., LIVANOS, E., JACKS, T., and TLSTY, T.D. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell 70, 923-935, 1992.
-
(1992)
Cell
, vol.70
, pp. 923-935
-
-
Livingstone, L.R.1
White, A.2
Sprouse, J.3
Livanos, E.4
Jacks, T.5
Tlsty, T.D.6
-
27
-
-
0024436330
-
Conservation of human telomere sequence (TTAGGG)n among vertebrates
-
MEYNE, J., RATLIFF, R.L., and MOYZIS, R.K. Conservation of human telomere sequence (TTAGGG)n among vertebrates, Proc. Natl. Acad. Sci. USA 86, 7049-53, 1989.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 7049-7053
-
-
Meyne, J.1
Ratliff, R.L.2
Moyzis, R.K.3
-
28
-
-
0028236846
-
Induction of WAF1/CIP1 by a p53-independent pathway
-
MICHIELI, P., CHEDID, M., LIN, D., PIERCE, J.H., MERCER, W.E., and GIVOL, D. Induction of WAF1/CIP1 by a p53-independent pathway. Cancer Res. 54, 3391-3395, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 3391-3395
-
-
Michieli, P.1
Chedid, M.2
Lin, D.3
Pierce, J.H.4
Mercer, W.E.5
Givol, D.6
-
29
-
-
0024325562
-
The human telomere terminal transferase is a ribonucleoprotein that synthesizes TTAGGG repeats
-
MORIN, G. The human telomere terminal transferase is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell 59, 521-529, 1990.
-
(1990)
Cell
, vol.59
, pp. 521-529
-
-
Morin, G.1
-
30
-
-
0028342664
-
Cloning the senescent cell-derived inhibitors of DNA synthesis using an expression screen
-
NODA, A., NING, Y., VENABLE, S.F., PEREIRA-SMITH, O.M., and SMITH, J.R. Cloning the senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp. Cell Res. 211, 90-98, 1994.
-
(1994)
Exp. Cell Res.
, vol.211
, pp. 90-98
-
-
Noda, A.1
Ning, Y.2
Venable, S.F.3
Pereira-Smith, O.M.4
Smith, J.R.5
-
31
-
-
0001029496
-
A theory of marginotomy
-
OLOVNIKOV, A.M. A theory of marginotomy. Dokaly Biochem. 201, 394-397, 1971.
-
(1971)
Dokaly Biochem.
, vol.201
, pp. 394-397
-
-
Olovnikov, A.M.1
-
32
-
-
0028340020
-
SV40-Transformed human cells in crisis exhibit changes that occur in normal cellular senescence
-
RUBELJ, I. and PEREIRA-SMITH, O.M. SV40-Transformed human cells in crisis exhibit changes that occur in normal cellular senescence. Exp. Cell Res. 211, 82-89, 1994.
-
(1994)
Exp. Cell Res.
, vol.211
, pp. 82-89
-
-
Rubelj, I.1
Pereira-Smith, O.M.2
-
33
-
-
0025729836
-
Defining the molecular mechanisms of human cell immortalization
-
SHAY, J.W., WRIGHT, W.E., and WERBIN, H. Defining the molecular mechanisms of human cell immortalization. Biochem. Biophys. Acta 1072, 1-7, 1991.
-
(1991)
Biochem. Biophys. Acta
, vol.1072
, pp. 1-7
-
-
Shay, J.W.1
Wright, W.E.2
Werbin, H.3
-
34
-
-
0028171292
-
G1 phase progression: Cycling on cue
-
SHERR, C.J. G1 phase progression: Cycling on cue. Cell 79, 551-555, 1994.
-
(1994)
Cell
, vol.79
, pp. 551-555
-
-
Sherr, C.J.1
-
35
-
-
0000133469
-
Defining cellular senescence in IMR-90 cells: A flow cytornertric analysis
-
SHERWOOD, S.W., RUSH, D., ELLSWORTH, J.L., and SCHIMKE, R.T. Defining cellular senescence in IMR-90 cells: A flow cytornertric analysis. Proc. Natl. Acad. Sci. USA 85, 9086-9090, 1989.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 9086-9090
-
-
Sherwood, S.W.1
Rush, D.2
Ellsworth, J.L.3
Schimke, R.T.4
-
36
-
-
0025150387
-
Failure to phosphorylate the retinoblastoma gene product in senescent human fibroblast
-
STEIN, G.H., BESSON, M., GORDON, L. Failure to phosphorylate the retinoblastoma gene product in senescent human fibroblast. Science 249, 666-669, 1990.
-
(1990)
Science
, vol.249
, pp. 666-669
-
-
Stein, G.H.1
Besson, M.2
Gordon, L.3
-
37
-
-
0027486732
-
Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes
-
VAZIRI, H., SCHACHTER, F., UCHIDA, I., WEI, L., ZHU, X., EFFROSS, R., COHEN, D., and HARLEY, C.B. Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes. Am. J. Hum. Genet. 52, 661-667, 1993.
-
(1993)
Am. J. Hum. Genet.
, vol.52
, pp. 661-667
-
-
Vaziri, H.1
Schachter, F.2
Uchida, I.3
Wei, L.4
Zhu, X.5
Effross, R.6
Cohen, D.7
Harley, C.B.8
-
38
-
-
0028077099
-
Evidence for a mitotic clock in human hematopoietic stem cells: Loss of telomeric DNA with age
-
VAZIRI, H., DRAGOWSKA, W., ALLSOPP, R.C., THOMAS, T.E., HARLEY, C.B., and LANSDORP, P.L. Evidence for a mitotic clock in human hematopoietic stem cells: Loss of telomeric DNA with age. Proc. Natl. Acad. Sci. USA 91, 9857-9860, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9857-9860
-
-
Vaziri, H.1
Dragowska, W.2
Allsopp, R.C.3
Thomas, T.E.4
Harley, C.B.5
Lansdorp, P.L.6
-
39
-
-
0015515155
-
Origin of the concatameric T4 DNA
-
WATSON, J.D. Origin of the concatameric T4 DNA. Nature New Biol. 239, 197-201, 1972.
-
(1972)
Nature New Biol.
, vol.239
, pp. 197-201
-
-
Watson, J.D.1
-
40
-
-
0026682717
-
Telomere positional effects and the regulation of cellular senescence
-
WRIGHT, W.E. and SHAY, J.W. Telomere positional effects and the regulation of cellular senescence. Trends Genet. 8, 193-197, 1992.
-
(1992)
Trends Genet.
, vol.8
, pp. 193-197
-
-
Wright, W.E.1
Shay, J.W.2
-
41
-
-
0027717617
-
p21 is a universal inhibitor of cyclin kinases
-
XIONG, Y., HANNON, G.J., ZHANG, H., CASSO, D., KOBAGASHI, R., BEACH, D. p21 is a universal inhibitor of cyclin kinases. Nature 366, 701-706, 1993.
-
(1993)
Nature
, vol.366
, pp. 701-706
-
-
Xiong, Y.1
Hannon, G.J.2
Zhang, H.3
Casso, D.4
Kobagashi, R.5
Beach, D.6
-
42
-
-
0026801977
-
Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
-
YIN, Y., TAINSKY, M.A., BISCHOFF, F.Z., STRONG, L.C., and WAHL, G.M. Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell 70, 937-948, 1992.
-
(1992)
Cell
, vol.70
, pp. 937-948
-
-
Yin, Y.1
Tainsky, M.A.2
Bischoff, F.Z.3
Strong, L.C.4
Wahl, G.M.5
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