Immunohistochemical expression of p53 in animal tumors: A methodological study using four anti-human p53 antibodies

Histology and Histopathology

Volumn 16, Issue 1, 2001, Pages 113-121

  Albaric, O ^a   Bret, L ^a   Amardeihl, M ^a   Delverdier, M ^a  

^a UNIVERSITÉ DE TOULOUSE   (France)

Author keywords

Domestic animals; Immunohistochemistry; Methodology; p53

Indexed keywords

MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; PROTEIN P53;

ACTINIC KERATOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER; CARCINOGENESIS; CAT; CATTLE; COLORECTAL CANCER; CONTROLLED STUDY; DOG; DOMESTIC ANIMAL; GENE MUTATION; HORSE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; METHODOLOGY; NONHUMAN; OSTEOSARCOMA; PROGNOSIS; PROTEIN EXPRESSION; SHEEP; SQUAMOUS CELL CARCINOMA; TUMOR SUPPRESSOR GENE;

ANIMALS; ANTIBODIES, NEOPLASM; CARCINOMA, SQUAMOUS CELL; CATS; CATTLE; COLORING AGENTS; DOGS; HORSES; HUMANS; IMMUNOHISTOCHEMISTRY; KERATOSIS; NEOPLASMS, EXPERIMENTAL; OSTEOSARCOMA; SHEEP; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA; BOS TAURUS; CANIS FAMILIARIS; EQUUS CABALLUS; FELIDAE; FELIS CATUS; OVIS ARIES;

EID: 0035148332     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Inhibition of UV-induced p53 mutations by sunscreens: Implications for skin cancer prevention
2. An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms
3. Cytoplasmic accumulation of p53 protein: An independent prognostic factor in colorectal adenocarcinomas
4. p53 alterations in human squamous cell carcinomas and carcinoma cell lines
5. Role of p53 in apoptosis, in apoptosis: Pharmacological implications and their therapeutic opportunities
6. Site-specific comparison of p53 immunostaining in squamous cell carcinomas
7. p53 mutations and overexpression in locally advanced breast cancers
8. Clinico-pathological correlation and prognostic significance of nuclear p53 protein in colorectal cancer
9. Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life
10. Prognostic significance of cytoplasmic p53 overexpression in colorectal cancer. An immunohistochemical analysis
11. Overexpression of tumor supressor protein in spontaneously arising neoplasms of dogs
12. p53 mutations in human cancers
13. Mutation of p53 the tumor suppressor gene in spontaneously occurring osteosarcomas of the dog
14. p53 immunohistochemistry in domestic animal tumors
15. P53, cell cycle control and apoptosis: Implications for cancer
16. Apoptosis, cancer and the p53 tumour suppressor gene
17. The p53 tumour suppressor gene
18. Expression of p53 gene in oral squamous cell carcinoma and its relation with clinical and pathological parameters and prognosis of patients
19. Le gène supresseur de tumeur P53 (première partie)
20. Sequence of an exon of the feline p53 gene-mutation in a lymphosarcoma
21. Sequence of an exon of the canine p53 gene-mutation in a papilloma
22. Sequence of an exon of tumour suppressor gene - A comparative study in domestic animals: Mutation in a feline solid mammary carcinoma
23. Canine tumour suppressor gene p53-mutation in a case of adenoma of circumanal glands
24. Forms and functions of p53
25. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
26. Analysis of the p53 gene in human precancerous actinic keratosis lesions and squamous cell cancers
27. Assessment of p53 protein expression in normal, begnin, and malignant oral mucosa
28. Molecular cloning and chromosomal mapping of feline p53 tumor suppressor gene
29. P53 tumor suppressor gene: Structure and function
30. Analysis of the equine tumor suppressor gene p53 in the normal horse and in eight cutaneous squamous cell carcinomas
31. Expression of p53 protein in oral squamous cell carcinomas and adjacent non-tumorous mucosa of the floor of the mouth: An archival immunohistochemical study using wet autoclave pretreatment for antigen retrieval
32. Subcellular localization of accumulated p53 in ovarian cancer cells
33. C-myc and bcl-2 modulate p53 function by altering p53 subcellular trafficking during the cell cycle
34. P53 tumor suppressor protein overexpression in osteogenic tumors of dogs
35. Immunohistochemical detection of p53 overexpression in paraffin wax-embedded squamous cell carcinomas of cattle, horses, cats and dogs
36. Detection of canine oral papillomavirus-DNA in canine oral squamous cell carcinomas and p53 overexpressing skin papillomas of the dog using the polymerase chain reaction and non-radioactive in situ hybridization
37. Isolation of canine p53 cDNA and detailed characterization of the full length canine p53 protein
38. Immunohistochemical expression of the p53 protein in testicular tumours in the dog
39. Immunohistochemical detection of p53 tumor suppressor gene protein in canine epithelial colorectal tumors
40. Point mutation of p53 tumor suppressor gene in bovine leukemia virus-induced lymphosarcoma