-
1
-
-
0028933233
-
Cloning and functional characterization of a novel ATP-sensitive potassium channel ubiquitously expressed in rat tissues, including pancreatic islets, pituitary, skeletal muscle, and heart
-
Inagaki N, Tsuura Y, Namba N, et al. Cloning and functional characterization of a novel ATP-sensitive potassium channel ubiquitously expressed in rat tissues, including pancreatic islets, pituitary, skeletal muscle, and heart. J Biol Chem. 1995;270:5691-5694.
-
(1995)
J Biol Chem
, vol.270
, pp. 5691-5694
-
-
Inagaki, N.1
Tsuura, Y.2
Namba, N.3
-
2
-
-
0028972501
-
Reconstitution of IKATP: An inward rectifier subunit plus the sulfonylurea receptor
-
Inagaki N, Gonoi T, Clement JPt, et al. Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor. Science. 1995;270:1166-1170.
-
(1995)
Science
, vol.270
, pp. 1166-1170
-
-
Inagaki, N.1
Gonoi, T.2
Clement, J.Pt.3
-
3
-
-
0029561629
-
Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic beta-cells, brain, heart and skeletal muscle
-
Sakura H, Ammala C, Smith PA, et al. Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic beta-cells, brain, heart and skeletal muscle. FEBS Lett. 1995;377:338-344.
-
(1995)
FEBS Lett
, vol.377
, pp. 338-344
-
-
Sakura, H.1
Ammala, C.2
Smith, P.A.3
-
4
-
-
0026621245
-
ABC transporters: From microorganisms to man
-
Higgins CF. ABC transporters: from microorganisms to man. Annu Rev Cell Biol. 1992;8:67-113.
-
(1992)
Annu Rev Cell Biol
, vol.8
, pp. 67-113
-
-
Higgins, C.F.1
-
5
-
-
0021741559
-
Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells
-
Ashcroft FM, Harrison DE, Ashcroft SJ. Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells. Nature. 1984;312:446-448.
-
(1984)
Nature
, vol.312
, pp. 446-448
-
-
Ashcroft, F.M.1
Harrison, D.E.2
Ashcroft, S.J.3
-
6
-
-
0021187646
-
Intracellular ATP directly blocks K+ channels in pancreatic B-cells
-
Cook DL, Hales CN. Intracellular ATP directly blocks K+ channels in pancreatic B-cells. Nature. 1984;311:271-273.
-
(1984)
Nature
, vol.311
, pp. 271-273
-
-
Cook, D.L.1
Hales, C.N.2
-
7
-
-
0026333684
-
The role of ATP and free ADP in metabolic coupling during fuel-stimulated insulin release from islet beta-cells in the isolated perfused rat pancreas
-
Ghosh A, Ronner P, Cheong E, et al. The role of ATP and free ADP in metabolic coupling during fuel-stimulated insulin release from islet beta-cells in the isolated perfused rat pancreas. J Biol Chem. 1991;266:22887-22892.
-
(1991)
J Biol Chem
, vol.266
, pp. 22887-22892
-
-
Ghosh, A.1
Ronner, P.2
Cheong, E.3
-
8
-
-
0030748260
-
Signal transduction mechanisms in nutrient-induced insulin secretion
-
Prentki M, Tornheim K, Corkey BE. Signal transduction mechanisms in nutrient-induced insulin secretion. Diabetologia. 1997;40(suppl 2):S32-S41.
-
(1997)
Diabetologia
, vol.40
, Issue.2 SUPPL.
-
-
Prentki, M.1
Tornheim, K.2
Corkey, B.E.3
-
9
-
-
0031005755
-
Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor
-
Tucker SJ, Gribble FM, Zhao C, et al. Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor. Nature. 1997;387:179-183.
-
(1997)
Nature
, vol.387
, pp. 179-183
-
-
Tucker, S.J.1
Gribble, F.M.2
Zhao, C.3
-
10
-
-
0033548244
-
Direct photoaffinity labeling of the Kir6.2 subunit of the ATP-sensitive K+ channel by 8-azido-ATP
-
Tanabe K, Tucker SJ, Matsuo M, et al. Direct photoaffinity labeling of the Kir6.2 subunit of the ATP-sensitive K+ channel by 8-azido-ATP. J Biol Chem. 1999;274:3931-3933.
-
(1999)
J Biol Chem
, vol.274
, pp. 3931-3933
-
-
Tanabe, K.1
Tucker, S.J.2
Matsuo, M.3
-
11
-
-
0037021430
-
Compromised ATP binding as a mechanism of phosphoinositide modulation of ATP-sensitive K+ channels
-
Wang C, Wang K, Wang W, et al. Compromised ATP binding as a mechanism of phosphoinositide modulation of ATP-sensitive K+ channels. FEBS Lett. 2002;532:177-182.
-
(2002)
FEBS Lett
, vol.532
, pp. 177-182
-
-
Wang, C.1
Wang, K.2
Wang, W.3
-
12
-
-
0030609142
-
Regulation of KATP channel activity by diazoxide and MgADP. Distinct functions of the two nucleotide binding folds of the sulfonylurea receptor
-
Shyng S, Ferrigni T, Nichols CG. Regulation of KATP channel activity by diazoxide and MgADP. Distinct functions of the two nucleotide binding folds of the sulfonylurea receptor. J Gen Physiol. 1997;110:643-654.
-
(1997)
J Gen Physiol
, vol.110
, pp. 643-654
-
-
Shyng, S.1
Ferrigni, T.2
Nichols, C.G.3
-
13
-
-
0032499773
-
MgATP activates the beta cell KATP channel by interaction with its SUR1 subunit
-
Gribble FM, Tucker SJ, Haug T, et al. MgATP activates the beta cell KATP channel by interaction with its SUR1 subunit. Proc Natl Acad Sci U S A. 1998;95:7185-7190.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 7185-7190
-
-
Gribble, F.M.1
Tucker, S.J.2
Haug, T.3
-
14
-
-
0034666295
-
Different binding properties and affinities for ATP and ADP among sulfonylurea receptor subtypes, SUR1, SUR2A, and SUR2B
-
Matsuo M, Tanabe K, Kioka N, et al. Different binding properties and affinities for ATP and ADP among sulfonylurea receptor subtypes, SUR1, SUR2A, and SUR2B. J Biol Chem. 2000;275:28757-28763.
-
(2000)
J Biol Chem
, vol.275
, pp. 28757-28763
-
-
Matsuo, M.1
Tanabe, K.2
Kioka, N.3
-
15
-
-
0026649107
-
Two sites for adenine-nucleotide regulation of ATP-sensitive potassium channels in mouse pancreatic beta-cells and HIT cells
-
Hopkins WF, Fatherazi S, Peter-Riesch B, et al. Two sites for adenine-nucleotide regulation of ATP-sensitive potassium channels in mouse pancreatic beta-cells and HIT cells. J Membr Biol. 1992;129:287-295.
-
(1992)
J Membr Biol
, vol.129
, pp. 287-295
-
-
Hopkins, W.F.1
Fatherazi, S.2
Peter-Riesch, B.3
-
16
-
-
0025136993
-
ATP-sensitive K+ channels: A link between B-cell metabolism and insulin secretion
-
Ashcroft FM, Rorsman P. ATP-sensitive K+ channels: a link between B-cell metabolism and insulin secretion. Biochem Soc Trans. 1990;18:109-111.
-
(1990)
Biochem Soc Trans
, vol.18
, pp. 109-111
-
-
Ashcroft, F.M.1
Rorsman, P.2
-
17
-
-
0034485703
-
Stimulus-secretion coupling of arginine-induced insulin release: Comparison between the cationic amino acid and its methyl ester
-
Sener A, Best LC, Yates AP, et al. Stimulus-secretion coupling of arginine-induced insulin release: comparison between the cationic amino acid and its methyl ester. Endocrine. 2000;13:329-340.
-
(2000)
Endocrine
, vol.13
, pp. 329-340
-
-
Sener, A.1
Best, L.C.2
Yates, A.P.3
-
18
-
-
0035956875
-
Defective trafficking and function of KATP channels caused by a sulfonylurea receptor 1 mutation associated with persistent hyperinsulinemic hypoglycemia of infancy
-
Cartier EA, Conti LR, Vandenberg CA, et al. Defective trafficking and function of KATP channels caused by a sulfonylurea receptor 1 mutation associated with persistent hyperinsulinemic hypoglycemia of infancy. Proc Natl Acad Sci U S A. 2001;98:2882-2887.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 2882-2887
-
-
Cartier, E.A.1
Conti, L.R.2
Vandenberg, C.A.3
-
19
-
-
0035929661
-
Identification and pharmacological correction of a membrane trafficking defect associated with a mutation in the sulfonylurea receptor causing familial hyperinsulinism
-
Partridge CJ, Beech DJ, Sivaprasadarao A. Identification and pharmacological correction of a membrane trafficking defect associated with a mutation in the sulfonylurea receptor causing familial hyperinsulinism. J Biol Chem. 2001;276:35947-35952.
-
(2001)
J Biol Chem
, vol.276
, pp. 35947-35952
-
-
Partridge, C.J.1
Beech, D.J.2
Sivaprasadarao, A.3
-
20
-
-
0037053340
-
Identification of a familial hyperinsulinism-causing mutation in the sulfonylurea receptor 1 that prevents normal trafficking and function of KATP channels
-
Taschenberger G, Mougey A, Shen S, et al. Identification of a familial hyperinsulinism-causing mutation in the sulfonylurea receptor 1 that prevents normal trafficking and function of KATP channels. J Biol Chem. 2002;277:17139-17146.
-
(2002)
J Biol Chem
, vol.277
, pp. 17139-17146
-
-
Taschenberger, G.1
Mougey, A.2
Shen, S.3
-
21
-
-
15644367096
-
A nonsense mutation in the inward rectifier potassium channel gene, Kir6.2, is associated with familial hyperinsulinism
-
Nestorowicz A, Inagaki N, Gonoi T, et al. A nonsense mutation in the inward rectifier potassium channel gene, Kir6.2, is associated with familial hyperinsulinism. Diabetes. 1997;46:1743-1748.
-
(1997)
Diabetes
, vol.46
, pp. 1743-1748
-
-
Nestorowicz, A.1
Inagaki, N.2
Gonoi, T.3
-
22
-
-
0030016913
-
Adenosine diphosphate as an intracellular regulator of insulin secretion
-
Nichols CG, Shyng SL, Nestorowicz A, et al. Adenosine diphosphate as an intracellular regulator of insulin secretion. Science. 1996;272:1785-1787.
-
(1996)
Science
, vol.272
, pp. 1785-1787
-
-
Nichols, C.G.1
Shyng, S.L.2
Nestorowicz, A.3
-
23
-
-
0033803049
-
Dominantly inherited hyperinsulinism caused by a mutation in the sulfonylurea receptor type 1
-
Huopio H, Reimann F, Ashfield R, et al. Dominantly inherited hyperinsulinism caused by a mutation in the sulfonylurea receptor type 1. J Clin Invest. 2000;106:897-906.
-
(2000)
J Clin Invest
, vol.106
, pp. 897-906
-
-
Huopio, H.1
Reimann, F.2
Ashfield, R.3
-
24
-
-
15844366738
-
Sequence variants in the sulfonylurea receptor (SUR) gene are associated with NIDDM in Caucasians
-
Inoue H, Ferrer J, Welling CM, et al. Sequence variants in the sulfonylurea receptor (SUR) gene are associated with NIDDM in Caucasians. Diabetes. 1996;45:825-831.
-
(1996)
Diabetes
, vol.45
, pp. 825-831
-
-
Inoue, H.1
Ferrer, J.2
Welling, C.M.3
-
25
-
-
0033007968
-
Variants in the sulphonylurea receptor gene: Association of the exon 16-3t variant with type II diabetes mellitus in Dutch Caucasians
-
Hart LM, de Knijff P, Dekker JM, et al. Variants in the sulphonylurea receptor gene: association of the exon 16-3t variant with type II diabetes mellitus in Dutch Caucasians. Diabetologia. 1999;42:617-620.
-
(1999)
Diabetologia
, vol.42
, pp. 617-620
-
-
Hart, L.M.1
De Knijff, P.2
Dekker, J.M.3
-
26
-
-
0033625771
-
Sulfonylurea receptor 1 gene variants are associated with gestational diabetes and type 2 diabetes but not with altered secretion of insulin
-
Rissanen J, Markkanen A, Karkkainen P, et al. Sulfonylurea receptor 1 gene variants are associated with gestational diabetes and type 2 diabetes but not with altered secretion of insulin. Diabetes Care. 2000;23:70-73.
-
(2000)
Diabetes Care
, vol.23
, pp. 70-73
-
-
Rissanen, J.1
Markkanen, A.2
Karkkainen, P.3
-
27
-
-
0031773333
-
Missense mutations in the pancreatic islet beta cell inwardly rectifying K+ channel gene (KIR6.2/BIR): A meta-analysis suggests a role in the polygenic basis of type II diabetes mellitus in Caucasians
-
Hani EH, Boutin P, Durand E, et al. Missense mutations in the pancreatic islet beta cell inwardly rectifying K+ channel gene (KIR6.2/BIR): a meta-analysis suggests a role in the polygenic basis of type II diabetes mellitus in Caucasians. Diabetologia. 1998;41:1511-1515.
-
(1998)
Diabetologia
, vol.41
, pp. 1511-1515
-
-
Hani, E.H.1
Boutin, P.2
Durand, E.3
-
28
-
-
0028845528
-
Linkage studies in NIDDM with markers near the sulphonylurea receptor gene
-
Stirling B, Cox NJ, Bell GI, et al. Linkage studies in NIDDM with markers near the sulphonylurea receptor gene. Diabetologia. 1995;38:1479-1481.
-
(1995)
Diabetologia
, vol.38
, pp. 1479-1481
-
-
Stirling, B.1
Cox, N.J.2
Bell, G.I.3
-
29
-
-
13344259308
-
Identification of microsatellite markers near the human genes encoding the beta-cell ATP-sensitive K+ channel and linkage studies with NIDDM in Japanese
-
Iwasaki N, Kawamura M, Yamagata K, et al. Identification of microsatellite markers near the human genes encoding the beta-cell ATP-sensitive K+ channel and linkage studies with NIDDM in Japanese. Diabetes. 1996;45:267-269.
-
(1996)
Diabetes
, vol.45
, pp. 267-269
-
-
Iwasaki, N.1
Kawamura, M.2
Yamagata, K.3
-
30
-
-
0029740428
-
Sequence variations in the human Kir6.2 gene, a subunit of the beta-cell ATP-sensitive K-channel: No association with NIDDM in while Caucasian subjects or evidence of abnormal function when expressed in vitro
-
Sakura H, Wat N, Horton V, et al. Sequence variations in the human Kir6.2 gene, a subunit of the beta-cell ATP-sensitive K-channel: no association with NIDDM in while Caucasian subjects or evidence of abnormal function when expressed in vitro. Diabetologia. 1996;39:1233-1236.
-
(1996)
Diabetologia
, vol.39
, pp. 1233-1236
-
-
Sakura, H.1
Wat, N.2
Horton, V.3
-
31
-
-
0030980371
-
The 31-cM region of chromosome 11 including the obesity gene tubby and ATP-sensitive potassium channel genes, SUR1 and Kir6.2, does not contain a major susceptibility locus for NIDDM in 127 non-Hispanic white affected sibships
-
Lindner T, Gragnoli C, Schulze J, et al. The 31-cM region of chromosome 11 including the obesity gene tubby and ATP-sensitive potassium channel genes, SUR1 and Kir6.2, does not contain a major susceptibility locus for NIDDM in 127 non-Hispanic white affected sibships. Diabetes. 1997;46:1227-1229.
-
(1997)
Diabetes
, vol.46
, pp. 1227-1229
-
-
Lindner, T.1
Gragnoli, C.2
Schulze, J.3
-
32
-
-
0141630107
-
Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice
-
Miki T, Nagashima K, Tashiro F, et al. Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice. Proc Natl Acad Sci U S A. 1998;95:10402-10406.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 10402-10406
-
-
Miki, T.1
Nagashima, K.2
Tashiro, F.3
-
33
-
-
0034048298
-
Diverse roles of K(ATP) channels learned from Kir6.2 genetically engineered mice
-
Seino S, Iwanaga T, Nagashima K, et al. Diverse roles of K(ATP) channels learned from Kir6.2 genetically engineered mice. Diabetes. 2000;49:311-318.
-
(2000)
Diabetes
, vol.49
, pp. 311-318
-
-
Seino, S.1
Iwanaga, T.2
Nagashima, K.3
-
34
-
-
0031041271
-
Familial persistent hyperinsulinemic hypoglycemia of infancy and mutations in the sulfonylurea receptor
-
Dunne MJ, Kane C, Shepherd RM, et al. Familial persistent hyperinsulinemic hypoglycemia of infancy and mutations in the sulfonylurea receptor. N Engl J Med. 1997;336:703-706.
-
(1997)
N Engl J Med
, vol.336
, pp. 703-706
-
-
Dunne, M.J.1
Kane, C.2
Shepherd, R.M.3
-
35
-
-
0029658788
-
Loss of functional KATP channels in pancreatic beta-cells causes persistent hyperinsulinemic hypoglycemia of infancy
-
Kane C, Shepherd RM, Squires PE, et al. Loss of functional KATP channels in pancreatic beta-cells causes persistent hyperinsulinemic hypoglycemia of infancy. Nat Med. 1996;2:1344-1347.
-
(1996)
Nat Med
, vol.2
, pp. 1344-1347
-
-
Kane, C.1
Shepherd, R.M.2
Squires, P.E.3
-
36
-
-
0034737811
-
Sur 1 knockout mice. A model for K(ATP) channel-independent regulation of insulin secretion
-
Seghers V, Nakazaki M, DeMayo F, et al. Sur 1 knockout mice. A model for K(ATP) channel-independent regulation of insulin secretion. J Biol Chem. 2000;275:9270-9277.
-
(2000)
J Biol Chem
, vol.275
, pp. 9270-9277
-
-
Seghers, V.1
Nakazaki, M.2
DeMayo, F.3
-
37
-
-
0003060067
-
-
Porte D, Sherwin RS, eds. Stamford, CT: Appleton and Lange
-
Cook DL, Taborsky GJ. In: Porte D, Sherwin RS, eds. Elleberg and Rifkin's Diabetes Mellitus, 5th ed. Stamford, CT: Appleton and Lange, 1997:49-73.
-
(1997)
Elleberg and Rifkin's Diabetes Mellitus, 5th Ed.
, pp. 49-73
-
-
Cook, D.L.1
Taborsky, G.J.2
-
38
-
-
0002591512
-
Diabetes mellitus
-
LeRoith D, Taylor SI, Olefsky JM, eds. Philadelphia: Lippincott-Raven
-
Atwater I, Mears D, Rojas E. Diabetes mellitus. In: LeRoith D, Taylor SI, Olefsky JM, eds. Diabetes Mellitus. Philadelphia: Lippincott-Raven, 1996:78-102.
-
(1996)
Diabetes Mellitus
, pp. 78-102
-
-
Atwater, I.1
Mears, D.2
Rojas, E.3
-
39
-
-
0024545428
-
Characterization of voltage-dependent Ca2+ channels in beta-cell line
-
Keahey HH, Rajan AS, Boyd AE 3rd, et al. Characterization of voltage-dependent Ca2+ channels in beta-cell line. Diabetes. 1989;38:188-193.
-
(1989)
Diabetes
, vol.38
, pp. 188-193
-
-
Keahey, H.H.1
Rajan, A.S.2
Boyd III, A.E.3
-
40
-
-
0023919695
-
Na channels and two types of Ca channels in rat pancreatic B cells identified with the reverse hemolytic plaque assay
-
Hiriart M, Matteson DR. Na channels and two types of Ca channels in rat pancreatic B cells identified with the reverse hemolytic plaque assay. J Gen Physiol. 1988;91:617-639.
-
(1988)
J Gen Physiol
, vol.91
, pp. 617-639
-
-
Hiriart, M.1
Matteson, D.R.2
-
41
-
-
0030872506
-
T-type calcium channels facilitate insulin secretion by enhancing general excitability in the insulin-secreting beta-cell line, INS-1
-
Bhattacharjee A, Whitehurst RM Jr, Zhang M, et al. T-type calcium channels facilitate insulin secretion by enhancing general excitability in the insulin-secreting beta-cell line, INS-1. Endocrinology. 1997;138:3735-3740.
-
(1997)
Endocrinology
, vol.138
, pp. 3735-3740
-
-
Bhattacharjee, A.1
Whitehurst Jr., R.M.2
Zhang, M.3
-
42
-
-
0026661115
-
Electrophysiology of stimulus-secretion coupling in human beta-cells
-
Misler S, Barnett DW, Gillis KD, et al. Electrophysiology of stimulus-secretion coupling in human beta-cells. Diabetes. 1992;41:1221-1228.
-
(1992)
Diabetes
, vol.41
, pp. 1221-1228
-
-
Misler, S.1
Barnett, D.W.2
Gillis, K.D.3
-
43
-
-
0016690451
-
Calcium antagonists and islet function. I. Inhibition of insulin release by verapamil
-
Devis G, Somers G, Van Obberghen E, et al. Calcium antagonists and islet function. I. Inhibition of insulin release by verapamil. Diabetes. 1975;24:247-251.
-
(1975)
Diabetes
, vol.24
, pp. 247-251
-
-
Devis, G.1
Somers, G.2
Van Obberghen, E.3
-
44
-
-
0028984692
-
Co-localization of L-type Ca2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells
-
Bokvist K, Eliasson L, Ammala C, et al. Co-localization of L-type Ca2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells. EMBO J. 1995;14:50-57.
-
(1995)
EMBO J
, vol.14
, pp. 50-57
-
-
Bokvist, K.1
Eliasson, L.2
Ammala, C.3
-
45
-
-
0026501745
-
Cloning of the alpha 1 subunit of a voltage-dependent calcium channel expressed in pancreatic beta cells
-
Seino S, Chen L, Seino M, et al. Cloning of the alpha 1 subunit of a voltage-dependent calcium channel expressed in pancreatic beta cells. Proc Natl Acad Sci U S A. 1992;89:584-588.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 584-588
-
-
Seino, S.1
Chen, L.2
Seino, M.3
-
46
-
-
0031945080
-
Voltage dependent calcium channels in adrenal glomerulosa cells and in insulin producing cells
-
Horvath A, Szabadkai G, Varnai P, et al. Voltage dependent calcium channels in adrenal glomerulosa cells and in insulin producing cells. Cell Calcium. 1998;23:33-42.
-
(1998)
Cell Calcium
, vol.23
, pp. 33-42
-
-
Horvath, A.1
Szabadkai, G.2
Varnai, P.3
-
47
-
-
0037379928
-
Ca v 1.3 is preferentially coupled to glucose-stimulated insulin secretion in the pancreatic beta-cell line INS-1
-
Liu G, Dilmac N, Hilliard N, et al. Ca v 1.3 is preferentially coupled to glucose-stimulated insulin secretion in the pancreatic beta-cell line INS-1. J Pharmacol Exp Ther. 2003;305:271-278.
-
(2003)
J Pharmacol Exp Ther
, vol.305
, pp. 271-278
-
-
Liu, G.1
Dilmac, N.2
Hilliard, N.3
-
48
-
-
0043076321
-
Impaired insulin secretion and glucose tolerance in beta cell-selective Ca(v) 1.2 Ca2+ channel null mice
-
Schulla V, Renstrom E, Feil R, et al. Impaired insulin secretion and glucose tolerance in beta cell-selective Ca(v) 1.2 Ca2+ channel null mice. EMBO J. 2003;22:3844-3854.
-
(2003)
EMBO J
, vol.22
, pp. 3844-3854
-
-
Schulla, V.1
Renstrom, E.2
Feil, R.3
-
49
-
-
0034794289
-
Requirement for the L-type Ca(2+) channel alpha(1D) subunit in postnatal pancreatic beta cell generation
-
Namkung Y, Skrypnyk N, Jeong MJ, et al. Requirement for the L-type Ca(2+) channel alpha(1D) subunit in postnatal pancreatic beta cell generation. J Clin Invest. 2001;108:1015-1022.
-
(2001)
J Clin Invest
, vol.108
, pp. 1015-1022
-
-
Namkung, Y.1
Skrypnyk, N.2
Jeong, M.J.3
-
50
-
-
0026740141
-
Dual functional role of membrane depolarization/Ca2+ influx in rat pancreatic B-cell
-
Sato Y, Aizawa T, Komatsu M, et al. Dual functional role of membrane depolarization/Ca2+ influx in rat pancreatic B-cell. Diabetes. 1992;41:438-443.
-
(1992)
Diabetes
, vol.41
, pp. 438-443
-
-
Sato, Y.1
Aizawa, T.2
Komatsu, M.3
-
51
-
-
0026632641
-
Evidence that glucose can control insulin release independently from its action on ATP-sensitive K+ channels in mouse B cells
-
Gembal M, Gilon P, Henquin JC. Evidence that glucose can control insulin release independently from its action on ATP-sensitive K+ channels in mouse B cells. J Clin Invest. 1992;89:1288-1295.
-
(1992)
J Clin Invest
, vol.89
, pp. 1288-1295
-
-
Gembal, M.1
Gilon, P.2
Henquin, J.C.3
-
52
-
-
0028786663
-
Glucose stimulation of insulin release in the absence of extracellular Ca2+ and in the absence of any increase in intracellular Ca2+ in rat pancreatic islets
-
Komatsu M, Schermerhorn T, Aizawa T, et al. Glucose stimulation of insulin release in the absence of extracellular Ca2+ and in the absence of any increase in intracellular Ca2+ in rat pancreatic islets. Proc Natl Acad Sci U S A. 1995;92:10728-10732.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 10728-10732
-
-
Komatsu, M.1
Schermerhorn, T.2
Aizawa, T.3
-
53
-
-
3242855498
-
-
Washington, DC: Elsevier
-
Prentki MV, Brun S, Glennon T, et al. Metabolic Coupling Factors in Beta Cell Insulin Secretion. Washington, DC: Elsevier, 1991:156-160.
-
(1991)
Metabolic Coupling Factors in Beta Cell Insulin Secretion
, pp. 156-160
-
-
Prentki, M.V.1
Brun, S.2
Glennon, T.3
-
54
-
-
0030042415
-
Evidence for an anaplerotic/malonyl-CoA pathway in pancreatic beta-cell nutrient signaling
-
Brun T, Roche E, Assimacopoulos-Jeannet F, et al. Evidence for an anaplerotic/malonyl-CoA pathway in pancreatic beta-cell nutrient signaling. Diabetes. 1996;45:190-198.
-
(1996)
Diabetes
, vol.45
, pp. 190-198
-
-
Brun, T.1
Roche, E.2
Assimacopoulos-Jeannet, F.3
-
55
-
-
0031750277
-
Long-term exposure of beta-INS cells to high glucose concentrations increases anaplerosis, lipogenesis, and lipogenic gene expression
-
Roche E, Farfari S, Witters LA, et al. Long-term exposure of beta-INS cells to high glucose concentrations increases anaplerosis, lipogenesis, and lipogenic gene expression. Diabetes. 1998;47:1086-1094.
-
(1998)
Diabetes
, vol.47
, pp. 1086-1094
-
-
Roche, E.1
Farfari, S.2
Witters, L.A.3
-
56
-
-
0028236988
-
More direct evidence for a malonyl-CoA-carnitine palmitoyltransferase I interaction as a key event in pancreatic beta-cell signaling
-
Chen S, Ogawa A, Ohneda M, et al. More direct evidence for a malonyl-CoA-carnitine palmitoyltransferase I interaction as a key event in pancreatic beta-cell signaling. Diabetes. 1994;43:878-883.
-
(1994)
Diabetes
, vol.43
, pp. 878-883
-
-
Chen, S.1
Ogawa, A.2
Ohneda, M.3
-
57
-
-
0031962444
-
Essential role of acetyl-CoA carboxylase in the glucose-induced insulin secretion in a pancreatic beta-cell line
-
Zhang S, Kim KH. Essential role of acetyl-CoA carboxylase in the glucose-induced insulin secretion in a pancreatic beta-cell line. Cell Signal. 1998;10:35-42.
-
(1998)
Cell Signal
, vol.10
, pp. 35-42
-
-
Zhang, S.1
Kim, K.H.2
-
58
-
-
0026733643
-
Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion
-
Prentki M, Vischer S, Glennon MC, et al. Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion. J Biol Chem. 1992;267:5802-5810.
-
(1992)
J Biol Chem
, vol.267
, pp. 5802-5810
-
-
Prentki, M.1
Vischer, S.2
Glennon, M.C.3
-
59
-
-
0027475668
-
N-myristylation of the catalytic subunit of cAMP-dependent protein kinase conveys structural stability
-
Yonemoto W, McGlone ML, Taylor SS. N-myristylation of the catalytic subunit of cAMP-dependent protein kinase conveys structural stability. J Biol Chem. 1993;268:2348-2352.
-
(1993)
J Biol Chem
, vol.268
, pp. 2348-2352
-
-
Yonemoto, W.1
McGlone, M.L.2
Taylor, S.S.3
-
60
-
-
0025721159
-
Pyruvate dehydrogenase and pyruvate carboxylase. Sites of pretranslational regulation by glucose of glucose-induced insulin release in pancreatic islets
-
MacDonald MJ, Kaysen JH, Moran SM, et al. Pyruvate dehydrogenase and pyruvate carboxylase. Sites of pretranslational regulation by glucose of glucose-induced insulin release in pancreatic islets. J Biol Chem. 1991;266:22392-22397.
-
(1991)
J Biol Chem
, vol.266
, pp. 22392-22397
-
-
MacDonald, M.J.1
Kaysen, J.H.2
Moran, S.M.3
-
61
-
-
0027199057
-
Glucose regulates acetyl-CoA carboxylase gene expression in a pancreatic beta-cell line (INS-1)
-
Brun T, Roche E, Kim KH, et al. Glucose regulates acetyl-CoA carboxylase gene expression in a pancreatic beta-cell line (INS-1). J Biol Chem. 1993;268:18905-18911.
-
(1993)
J Biol Chem
, vol.268
, pp. 18905-18911
-
-
Brun, T.1
Roche, E.2
Kim, K.H.3
-
62
-
-
0029132238
-
Stimulation of cloned human glucagon-like peptide 1 receptor expressed in HEK 293 cells induces cAMP-dependent activation of calcium-induced calcium release
-
Gromada J, Rorsman P, Dissing S, et al. Stimulation of cloned human glucagon-like peptide 1 receptor expressed in HEK 293 cells induces cAMP-dependent activation of calcium-induced calcium release. FEBS Lett. 1995;373:182-186.
-
(1995)
FEBS Lett
, vol.373
, pp. 182-186
-
-
Gromada, J.1
Rorsman, P.2
Dissing, S.3
-
63
-
-
0027235323
-
Calcium-independent potentiation of insulin release by cyclic AMP in single beta-cells
-
Ammala C, Ashcroft FM, Rorsman P. Calcium-independent potentiation of insulin release by cyclic AMP in single beta-cells. Nature. 1993;363:356-358.
-
(1993)
Nature
, vol.363
, pp. 356-358
-
-
Ammala, C.1
Ashcroft, F.M.2
Rorsman, P.3
-
64
-
-
0023020084
-
Regulation of insulin secretion by cAMP in rat islets of Langerhans permeabilised by high-voltage discharge
-
Jones PM, Fyles JM, Howell SL. Regulation of insulin secretion by cAMP in rat islets of Langerhans permeabilised by high-voltage discharge. FEBS Lett. 1986;205:205-209.
-
(1986)
FEBS Lett
, vol.205
, pp. 205-209
-
-
Jones, P.M.1
Fyles, J.M.2
Howell, S.L.3
-
65
-
-
0030945044
-
Protein kinase A-dependent stimulation of exocytosis in mouse pancreatic beta-cells by glucose-dependent insulinotropic polypeptide
-
Ding WG, Gromada J. Protein kinase A-dependent stimulation of exocytosis in mouse pancreatic beta-cells by glucose-dependent insulinotropic polypeptide. Diabetes. 1997;46:615-621.
-
(1997)
Diabetes
, vol.46
, pp. 615-621
-
-
Ding, W.G.1
Gromada, J.2
-
66
-
-
0031965604
-
Glucagon-like peptide 1 (7-36) amide stimulates exocytosis in human pancreatic beta-cells by both proximal and distal regulatory steps in stimulus-secretion coupling
-
Gromada J, Bokvist K, Ding WG, et al. Glucagon-like peptide 1 (7-36) amide stimulates exocytosis in human pancreatic beta-cells by both proximal and distal regulatory steps in stimulus-secretion coupling. Diabetes. 1998;47:57-65.
-
(1998)
Diabetes
, vol.47
, pp. 57-65
-
-
Gromada, J.1
Bokvist, K.2
Ding, W.G.3
-
67
-
-
0029859599
-
Decreased glucose-induced cAMP and insulin release in islets of diabetic rats: Reversal by IBMX, glucagon, GIP
-
Dachicourt N, Serradas P, Giroix MH, et al. Decreased glucose-induced cAMP and insulin release in islets of diabetic rats: reversal by IBMX, glucagon, GIP. Am J Physiol. 1996;271:E725-E732.
-
(1996)
Am J Physiol
, vol.271
-
-
Dachicourt, N.1
Serradas, P.2
Giroix, M.H.3
-
68
-
-
0028054862
-
Pituitary adenylate cyclase activating polypeptide is an extraordinarily potent intra-pancreatic regulator of insulin secretion from islet beta-cells
-
Yada T, Sakurada M, Ihida K, et al. Pituitary adenylate cyclase activating polypeptide is an extraordinarily potent intra-pancreatic regulator of insulin secretion from islet beta-cells. J Biol Chem. 1994;269:1290-1293.
-
(1994)
J Biol Chem
, vol.269
, pp. 1290-1293
-
-
Yada, T.1
Sakurada, M.2
Ihida, K.3
-
69
-
-
0030030660
-
A wortmannin-sensitive signal transduction pathway is involved in the stimulation of insulin release by vasoactive intestinal polypeptide and pituitary adenylate cyclase-activating polypeptide
-
Straub SG, Sharp GW. A wortmannin-sensitive signal transduction pathway is involved in the stimulation of insulin release by vasoactive intestinal polypeptide and pituitary adenylate cyclase-activating polypeptide. J Biol Chem. 1996;271:1660-1668.
-
(1996)
J Biol Chem
, vol.271
, pp. 1660-1668
-
-
Straub, S.G.1
Sharp, G.W.2
-
70
-
-
0024998368
-
Effects of insulin secretagogues on protein kinase C-catalyzed phosphorylation of an endogenous substrate in isolated pancreatic islets
-
Easom RA, Landt M, Colca JR, et al. Effects of insulin secretagogues on protein kinase C-catalyzed phosphorylation of an endogenous substrate in isolated pancreatic islets. J Biol Chem. 1990;265:14938-14946.
-
(1990)
J Biol Chem
, vol.265
, pp. 14938-14946
-
-
Easom, R.A.1
Landt, M.2
Colca, J.R.3
-
71
-
-
0023616645
-
Receptor-mediated adenylate cyclase-coupled mechanism for PGE2 inhibition of insulin secretion in HIT cells
-
Robertson RP, Tsai P, Little SA, et al. Receptor-mediated adenylate cyclase-coupled mechanism for PGE2 inhibition of insulin secretion in HIT cells. Diabetes. 1987;36:1047-1053.
-
(1987)
Diabetes
, vol.36
, pp. 1047-1053
-
-
Robertson, R.P.1
Tsai, P.2
Little, S.A.3
-
72
-
-
0028846161
-
Interaction of glucagon-like peptide-I (GLP-1) and galanin in insulin (beta TC-1)- and somatostatin (RIN T3)-secreting cells and evidence that both peptides have no receptors on glucagon (INR1G9)-secreting cells
-
Fehmann HC, Janssen M, Goke B. Interaction of glucagon-like peptide-I (GLP-1) and galanin in insulin (beta TC-1)- and somatostatin (RIN T3)-secreting cells and evidence that both peptides have no receptors on glucagon (INR1G9)-secreting cells. Acta Diabetol. 1995;32:176-181.
-
(1995)
Acta Diabetol
, vol.32
, pp. 176-181
-
-
Fehmann, H.C.1
Janssen, M.2
Goke, B.3
-
73
-
-
0028988140
-
Gi2 and Gi3 proteins mediate the inhibition of adenylyl cyclase by galanin in the RINm5F cell
-
McDermott AM, Sharp GW. Gi2 and Gi3 proteins mediate the inhibition of adenylyl cyclase by galanin in the RINm5F cell. Diabetes. 1995;44:453-459.
-
(1995)
Diabetes
, vol.44
, pp. 453-459
-
-
McDermott, A.M.1
Sharp, G.W.2
-
74
-
-
0030463279
-
Molecular machinery mediating vesicle budding, docking and fusion
-
Sollner TH, Rothman JE. Molecular machinery mediating vesicle budding, docking and fusion. Experientia. 1996;52:1021-1025.
-
(1996)
Experientia
, vol.52
, pp. 1021-1025
-
-
Sollner, T.H.1
Rothman, J.E.2
-
75
-
-
0027413655
-
SNAP receptors implicated in vesicle targeting and fusion
-
Sollner T, Whiteheart SW, Brunner M, et al. SNAP receptors implicated in vesicle targeting and fusion. Nature. 1993;362:318-324.
-
(1993)
Nature
, vol.362
, pp. 318-324
-
-
Sollner, T.1
Whiteheart, S.W.2
Brunner, M.3
-
76
-
-
3543096759
-
Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution
-
Sutton RB, Fasshauer D, Jahn R, et al. Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution. Nature. 1998;395:347-353.
-
(1998)
Nature
, vol.395
, pp. 347-353
-
-
Sutton, R.B.1
Fasshauer, D.2
Jahn, R.3
-
77
-
-
0028061861
-
Synaptotagmin I: A major Ca2+ sensor for transmitter release at a central synapse
-
Geppert M, Goda Y, Hammer RE, et al. Synaptotagmin I: a major Ca2+ sensor for transmitter release at a central synapse. Cell. 1994;79:717-727.
-
(1994)
Cell
, vol.79
, pp. 717-727
-
-
Geppert, M.1
Goda, Y.2
Hammer, R.E.3
-
78
-
-
0036151862
-
Molecular determinants of exocytosis
-
Bruns D, Jahn R. Molecular determinants of exocytosis. Pflugers Arch. 2002;443:333-338.
-
(2002)
Pflugers Arch
, vol.443
, pp. 333-338
-
-
Bruns, D.1
Jahn, R.2
-
79
-
-
0028580733
-
Identification of synaptic proteins and their isoform mRNAs in compartments of pancreatic endocrine cells
-
Jacobsson G, Bean AJ, Scheller RH, et al. Identification of synaptic proteins and their isoform mRNAs in compartments of pancreatic endocrine cells. Proc Natl Acad Sci U S A. 1994;91:12487-12491.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 12487-12491
-
-
Jacobsson, G.1
Bean, A.J.2
Scheller, R.H.3
-
80
-
-
0028940786
-
SNAP-25 is expressed in islets of Langerhans and is involved in insulin release
-
Sadoul K, Lang J, Montecucco C, et al. SNAP-25 is expressed in islets of Langerhans and is involved in insulin release. J Cell Biol. 1995;128:1019-1028.
-
(1995)
J Cell Biol
, vol.128
, pp. 1019-1028
-
-
Sadoul, K.1
Lang, J.2
Montecucco, C.3
-
81
-
-
9044235180
-
Characterization of SNARE protein expression in beta cell lines and pancreatic islets
-
Wheeler MB, Sheu L, Ghai M, et al. Characterization of SNARE protein expression in beta cell lines and pancreatic islets. Endocrinology. 1996;137:1340-1348.
-
(1996)
Endocrinology
, vol.137
, pp. 1340-1348
-
-
Wheeler, M.B.1
Sheu, L.2
Ghai, M.3
-
82
-
-
0031440274
-
Syntaxin, but not soluble NSF attachment protein (SNAP), biosynthesis by rat pancreatic islets is regulated by glucose in parallel with proinsulin biosynthesis
-
Nagamatsu S, Nakamichi Y, Katahira H. Syntaxin, but not soluble NSF attachment protein (SNAP), biosynthesis by rat pancreatic islets is regulated by glucose in parallel with proinsulin biosynthesis. Diabetologia. 1997;40:1396-1402.
-
(1997)
Diabetologia
, vol.40
, pp. 1396-1402
-
-
Nagamatsu, S.1
Nakamichi, Y.2
Katahira, H.3
-
83
-
-
11944258877
-
VAMP-2 and cellubrevin are expressed in pancreatic beta-cells and are essential for Ca(2+)-but not for GTP gamma S-induced insulin secretion
-
Regazzi R, Wollheim CB, Lang J, et al. VAMP-2 and cellubrevin are expressed in pancreatic beta-cells and are essential for Ca(2+)-but not for GTP gamma S-induced insulin secretion. EMBO J. 1995;14:2723-2730.
-
(1995)
EMBO J
, vol.14
, pp. 2723-2730
-
-
Regazzi, R.1
Wollheim, C.B.2
Lang, J.3
-
84
-
-
0030727151
-
Localization and functional role of synaptotagmin III in insulin secretory vesicles in pancreatic beta-cells
-
Mizuta M, Kurose T, Miki T, et al. Localization and functional role of synaptotagmin III in insulin secretory vesicles in pancreatic beta-cells. Diabetes. 1997;46:2002-2006.
-
(1997)
Diabetes
, vol.46
, pp. 2002-2006
-
-
Mizuta, M.1
Kurose, T.2
Miki, T.3
-
85
-
-
0041344686
-
Regulation of insulin exocytosis by Munc13-1
-
Sheu L, Pasyk EA, Ji J, et al. Regulation of insulin exocytosis by Munc13-1. J Biol Chem. 2003;278:27556-27563.
-
(2003)
J Biol Chem
, vol.278
, pp. 27556-27563
-
-
Sheu, L.1
Pasyk, E.A.2
Ji, J.3
-
86
-
-
0036261251
-
Fast insulin secretion reflects exocytosis of docked granules in mouse pancreatic B-cells
-
Olofsson CS, Gopel SO, Barg S, et al. Fast insulin secretion reflects exocytosis of docked granules in mouse pancreatic B-cells. Pflugers Arch. 2002;444:43-51.
-
(2002)
Pflugers Arch
, vol.444
, pp. 43-51
-
-
Olofsson, C.S.1
Gopel, S.O.2
Barg, S.3
-
87
-
-
0035201145
-
Fast exocytosis with few Ca(2+) channels in insulin-secreting mouse pancreatic B cells
-
Barg S, Ma X, Eliasson L, et al. Fast exocytosis with few Ca(2+) channels in insulin-secreting mouse pancreatic B cells. Biophys J. 2001;81:3308-3323.
-
(2001)
Biophys J
, vol.81
, pp. 3308-3323
-
-
Barg, S.1
Ma, X.2
Eliasson, L.3
-
88
-
-
0036310678
-
A subset of 50 secretory granules in close contact with L-type Ca2+ channels accounts for first-phase insulin secretion in mouse beta-cells
-
Barg S, Eliasson L, Renstrom E, et al. A subset of 50 secretory granules in close contact with L-type Ca2+ channels accounts for first-phase insulin secretion in mouse beta-cells. Diabetes. 2002;51(suppl 1):S74-S82.
-
(2002)
Diabetes
, vol.51
, Issue.1 SUPPL.
-
-
Barg, S.1
Eliasson, L.2
Renstrom, E.3
-
89
-
-
0033178286
-
CaM kinase II-dependent mobilization of secretory granules underlies acetylcholine-induced stimulation of exocytosis in mouse pancreatic B-cells
-
Gromada J, Hoy M, Renstrom E, et al. CaM kinase II-dependent mobilization of secretory granules underlies acetylcholine-induced stimulation of exocytosis in mouse pancreatic B-cells. J Physiol. 1999;518:745-759.
-
(1999)
J Physiol
, vol.518
, pp. 745-759
-
-
Gromada, J.1
Hoy, M.2
Renstrom, E.3
-
90
-
-
0037122871
-
Delay between fusion pore opening and peptide release from large dense-core vesicles in neuroendocrine cells
-
Barg S, Olofsson CS, Schriever-Abeln J, et al. Delay between fusion pore opening and peptide release from large dense-core vesicles in neuroendocrine cells. Neuron. 2002;33:287-299.
-
(2002)
Neuron
, vol.33
, pp. 287-299
-
-
Barg, S.1
Olofsson, C.S.2
Schriever-Abeln, J.3
-
91
-
-
0026664632
-
Resolution of regulated secretion into sequential MgATP-dependent and calcium-dependent stages mediated by distinct cytosolic proteins
-
Hay JC, Martin TF. Resolution of regulated secretion into sequential MgATP-dependent and calcium-dependent stages mediated by distinct cytosolic proteins. J Cell Biol. 1992;119:139-151.
-
(1992)
J Cell Biol
, vol.119
, pp. 139-151
-
-
Hay, J.C.1
Martin, T.F.2
-
92
-
-
0034410505
-
The cell physiology of biphasic insulin secretion
-
Rorsman P, Eliasson L, Renstrom E, et al. The cell physiology of biphasic insulin secretion. News Physiol Sci. 2000;15:72-77.
-
(2000)
News Physiol Sci
, vol.15
, pp. 72-77
-
-
Rorsman, P.1
Eliasson, L.2
Renstrom, E.3
-
93
-
-
0034956026
-
Priming of insulin granules for exocytosis by granular Cl(-) uptake and acidification
-
Barg S, Huang P, Eliasson L, et al. Priming of insulin granules for exocytosis by granular Cl(-) uptake and acidification. J Cell Sci. 2001;114:2145-2154.
-
(2001)
J Cell Sci
, vol.114
, pp. 2145-2154
-
-
Barg, S.1
Huang, P.2
Eliasson, L.3
-
94
-
-
0029767014
-
The exocytotic process of insulin secretion and its regulation by Ca2+ and G-proteins
-
Wollheim CBL, Regazzi J. R. The exocytotic process of insulin secretion and its regulation by Ca2+ and G-proteins. Diabetes Rev. 1996;4:277-297.
-
(1996)
Diabetes Rev
, vol.4
, pp. 277-297
-
-
Wollheim, C.B.L.1
Regazzi, J.R.2
-
95
-
-
0032472437
-
Ca 2+-independent insulin exocytosis induced by alpha-latrotoxin requires latrophilin, a G protein-coupled receptor
-
Lang J, Ushkaryov Y, Grasso A, et al. Ca 2+-independent insulin exocytosis induced by alpha-latrotoxin requires latrophilin, a G protein-coupled receptor. EMBO J. 1998;17:648-657.
-
(1998)
EMBO J
, vol.17
, pp. 648-657
-
-
Lang, J.1
Ushkaryov, Y.2
Grasso, A.3
-
96
-
-
0001575657
-
Augmentation of insulin release by glucose in the absence of extracellular Ca2+: New insights into stimulus-secretion coupling
-
Komatsu M, Schermerhorn T, Noda M, et al. Augmentation of insulin release by glucose in the absence of extracellular Ca2+: new insights into stimulus-secretion coupling. Diabetes. 1997;46:1928-1938.
-
(1997)
Diabetes
, vol.46
, pp. 1928-1938
-
-
Komatsu, M.1
Schermerhorn, T.2
Noda, M.3
-
97
-
-
0029092604
-
Direct control of exocytosis by receptor-mediated activation of the heterotrimeric GTPases Gi and G(o) or by the expression of their active G alpha subunits
-
Lang J, Nishimoto I, Okamoto T, et al. Direct control of exocytosis by receptor-mediated activation of the heterotrimeric GTPases Gi and G(o) or by the expression of their active G alpha subunits. EMBO J. 1995;14:3635-3644.
-
(1995)
EMBO J
, vol.14
, pp. 3635-3644
-
-
Lang, J.1
Nishimoto, I.2
Okamoto, T.3
-
98
-
-
0030056516
-
Glucose- and GTP-dependent stimulation of the carboxyl methylation of CDC42 in rodent and human pancreatic islets and pure beta cells. Evidence for an essential role of GTP-binding proteins in nutrient-induced insulin secretion
-
Kowluru A, Seavey SE, Li G, et al. Glucose- and GTP-dependent stimulation of the carboxyl methylation of CDC42 in rodent and human pancreatic islets and pure beta cells. Evidence for an essential role of GTP-binding proteins in nutrient-induced insulin secretion. J Clin Invest. 1996;98:540-555.
-
(1996)
J Clin Invest
, vol.98
, pp. 540-555
-
-
Kowluru, A.1
Seavey, S.E.2
Li, G.3
-
99
-
-
0029812387
-
Expression, localization and functional role of small GTPases of the Rab3 family in insulin-secreting cells
-
Regazzi R, Ravazzola M, Iezzi M, et al. Expression, localization and functional role of small GTPases of the Rab3 family in insulin-secreting cells. J Cell Sci. 1996;109:2265-2273.
-
(1996)
J Cell Sci
, vol.109
, pp. 2265-2273
-
-
Regazzi, R.1
Ravazzola, M.2
Iezzi, M.3
-
100
-
-
0032480888
-
Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP
-
de Rooij J, Zwartkruis FJ, Verheijen MH, et al. Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP. Nature. 1998;396:474-477.
-
(1998)
Nature
, vol.396
, pp. 474-477
-
-
De Rooij, J.1
Zwartkruis, F.J.2
Verheijen, M.H.3
-
101
-
-
0032545328
-
A family of cAMP-binding proteins that directly activate Rap1
-
Kawasaki H, Springett GM, Mochizuki N, et al. A family of cAMP-binding proteins that directly activate Rap1. Science. 1998;282:2275-2279.
-
(1998)
Science
, vol.282
, pp. 2275-2279
-
-
Kawasaki, H.1
Springett, G.M.2
Mochizuki, N.3
-
102
-
-
0035824548
-
Critical role of cAMP-GEFII-Rim2 complex in incretin-potentiated insulin secretion
-
Kashima Y, Miki T, Shibasaki T, et al. Critical role of cAMP-GEFII-Rim2 complex in incretin-potentiated insulin secretion. J Biol Chem. 2001;276:46046-46053.
-
(2001)
J Biol Chem
, vol.276
, pp. 46046-46053
-
-
Kashima, Y.1
Miki, T.2
Shibasaki, T.3
-
103
-
-
0033769693
-
cAMP-GEFII is a direct target of cAMP in regulated exocytosis
-
Ozaki N, Shibasaki T, Kashima Y, et al. cAMP-GEFII is a direct target of cAMP in regulated exocytosis. Nat Cell Biol. 2000;2:805-811.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 805-811
-
-
Ozaki, N.1
Shibasaki, T.2
Kashima, Y.3
-
104
-
-
0347990624
-
Epac: A new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic beta-cell
-
Holz GG. Epac: a new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic beta-cell. Diabetes. 2004;53:5-13.
-
(2004)
Diabetes
, vol.53
, pp. 5-13
-
-
Holz, G.G.1
-
105
-
-
0037337832
-
SUR1 regulates PKA-independent cAMP-induced granule priming in mouse pancreatic B-cells
-
Eliasson L, Ma X, Renstrom E, et al. SUR1 regulates PKA-independent cAMP-induced granule priming in mouse pancreatic B-cells. J Gen Physiol. 2003;121:181-197.
-
(2003)
J Gen Physiol
, vol.121
, pp. 181-197
-
-
Eliasson, L.1
Ma, X.2
Renstrom, E.3
-
106
-
-
1542289732
-
Interaction of ATP sensor, cAMP sensor, Ca2+ sensor, and voltage-dependent Ca2+ channel in insulin granule exocytosis
-
Shibasaki T, Sunaga Y, Fujimoto K, et al. Interaction of ATP sensor, cAMP sensor, Ca2+ sensor, and voltage-dependent Ca2+ channel in insulin granule exocytosis. J Biol Chem. 2004;279:7956-7961.
-
(2004)
J Biol Chem
, vol.279
, pp. 7956-7961
-
-
Shibasaki, T.1
Sunaga, Y.2
Fujimoto, K.3
-
107
-
-
0024413349
-
Localisation of islet amyloid peptide in lipofuscin bodies and secretory granules of human B-cells and in islets of type-2 diabetic subjects
-
Clark A, Edwards CA, Ostle LR, et al. Localisation of islet amyloid peptide in lipofuscin bodies and secretory granules of human B-cells and in islets of type-2 diabetic subjects. Cell Tissue Res. 1989;257:179-185.
-
(1989)
Cell Tissue Res
, vol.257
, pp. 179-185
-
-
Clark, A.1
Edwards, C.A.2
Ostle, L.R.3
-
108
-
-
0024307842
-
Co-localization of islet amyloid polypeptide and insulin in the B cell secretory granules of the human pancreatic islets
-
Lukinius A, Wilander E, Westermark GT, et al. Co-localization of islet amyloid polypeptide and insulin in the B cell secretory granules of the human pancreatic islets. Diabetologia. 1989;32:240-244.
-
(1989)
Diabetologia
, vol.32
, pp. 240-244
-
-
Lukinius, A.1
Wilander, E.2
Westermark, G.T.3
-
109
-
-
0025302287
-
Evidence of cosecretion of islet amyloid polypeptide and insulin by beta-cells
-
Kahn SE, D'Alessio DA, Schwartz MW, et al. Evidence of cosecretion of islet amyloid polypeptide and insulin by beta-cells. Diabetes. 1990;39:634-638.
-
(1990)
Diabetes
, vol.39
, pp. 634-638
-
-
Kahn, S.E.1
D'Alessio, D.A.2
Schwartz, M.W.3
-
110
-
-
0033758248
-
Amyloidogenicity of recombinant human pro-islet amyloid polypeptide (ProIAPP)
-
Krampert M, Bernhagen J, Schmucker J, et al. Amyloidogenicity of recombinant human pro-islet amyloid polypeptide (ProIAPP). Chem Biol. 2000;7:855-871.
-
(2000)
Chem Biol
, vol.7
, pp. 855-871
-
-
Krampert, M.1
Bernhagen, J.2
Schmucker, J.3
-
111
-
-
0030064237
-
Processing of pro-islet amyloid polypeptide (proIAPP) by the prohormone convertase PC2
-
Badman MK, Shennan KI, Jermany JL, et al. Processing of pro-islet amyloid polypeptide (proIAPP) by the prohormone convertase PC2. FEBS Lett. 1996;378:227-231.
-
(1996)
FEBS Lett
, vol.378
, pp. 227-231
-
-
Badman, M.K.1
Shennan, K.I.2
Jermany, J.L.3
-
112
-
-
0035123349
-
The prohormone convertase enzyme 2 (PC2) is essential for processing pro-islet amyloid polypeptide at the NH2-terminal cleavage site
-
Wang J, Xu J, Finnerty J, et al. The prohormone convertase enzyme 2 (PC2) is essential for processing pro-islet amyloid polypeptide at the NH2-terminal cleavage site. Diabetes. 2001;50:534-539.
-
(2001)
Diabetes
, vol.50
, pp. 534-539
-
-
Wang, J.1
Xu, J.2
Finnerty, J.3
-
113
-
-
0033891391
-
Processing of synthetic pro-islet amyloid polypeptide (proIAPP) 'amylin' by recombinant prohormone convertase enzymes, PC2 and PC3, in vitro
-
Higham CE, Hull RL, Lawrie L, et al. Processing of synthetic pro-islet amyloid polypeptide (proIAPP) 'amylin' by recombinant prohormone convertase enzymes, PC2 and PC3, in vitro. Eur J Biochem. 2000;267:4998-5004.
-
(2000)
Eur J Biochem
, vol.267
, pp. 4998-5004
-
-
Higham, C.E.1
Hull, R.L.2
Lawrie, L.3
-
114
-
-
0346099381
-
Role of beta-cell prohormone convertase (PC) 1/3 in processing of pro-islet amyloid polypeptide
-
Marzban L, Trigo-Gonzalez G, Zhu X, et al. Role of beta-cell prohormone convertase (PC) 1/3 in processing of pro-islet amyloid polypeptide. Diabetes. 2004;53:141-148.
-
(2004)
Diabetes
, vol.53
, pp. 141-148
-
-
Marzban, L.1
Trigo-Gonzalez, G.2
Zhu, X.3
-
115
-
-
0023787576
-
Amyloid fibrils formed from a segment of the pancreatic islet amyloid protein
-
Glenner GG, Eanes ED, Wiley CA. Amyloid fibrils formed from a segment of the pancreatic islet amyloid protein. Biochem Biophys Res Commun. 1988;155:608-614.
-
(1988)
Biochem Biophys Res Commun
, vol.155
, pp. 608-614
-
-
Glenner, G.G.1
Eanes, E.D.2
Wiley, C.A.3
-
117
-
-
0033534397
-
Watching amyloid fibrils grow by time-lapse atomic force microscopy
-
Goldsbury C, Kistler J, Aebi U, et al. Watching amyloid fibrils grow by time-lapse atomic force microscopy. J Mol Biol. 1999;285:33-39.
-
(1999)
J Mol Biol
, vol.285
, pp. 33-39
-
-
Goldsbury, C.1
Kistler, J.2
Aebi, U.3
-
118
-
-
0033856165
-
Amyloid fibril formation from full-length and fragments of amylin
-
Goldsbury C, Goldie K, Pellaud J, et al. Amyloid fibril formation from full-length and fragments of amylin. J Struct Biol. 2000;130:352-362.
-
(2000)
J Struct Biol
, vol.130
, pp. 352-362
-
-
Goldsbury, C.1
Goldie, K.2
Pellaud, J.3
-
119
-
-
0034001363
-
Direct measurement of islet amyloid polypeptide fibrillogenesis by mass spectrometry
-
Larson JL, Ko E, Miranker AD. Direct measurement of islet amyloid polypeptide fibrillogenesis by mass spectrometry. Protein Sci. 2000;9:427-431.
-
(2000)
Protein Sci
, vol.9
, pp. 427-431
-
-
Larson, J.L.1
Ko, E.2
Miranker, A.D.3
-
120
-
-
0035804936
-
Identification of a novel human islet amyloid polypeptide beta-sheet domain and factors influencing fibrillogenesis
-
Jaikaran ET, Higham CE, Serpell LC, et al. Identification of a novel human islet amyloid polypeptide beta-sheet domain and factors influencing fibrillogenesis. J Mol Biol. 2001;308:515-525.
-
(2001)
J Mol Biol
, vol.308
, pp. 515-525
-
-
Jaikaran, E.T.1
Higham, C.E.2
Serpell, L.C.3
-
121
-
-
0033579545
-
Analysis of amylin cleavage products provides new insights into the amyloidogenic region of human amylin
-
Nilsson MR, Raleigh DP. Analysis of amylin cleavage products provides new insights into the amyloidogenic region of human amylin. J Mol Biol. 1999;294:1375-1385.
-
(1999)
J Mol Biol
, vol.294
, pp. 1375-1385
-
-
Nilsson, M.R.1
Raleigh, D.P.2
-
122
-
-
0035161120
-
Synthesis and purification of amyloidogenic peptides
-
Nilsson MR, Nguyen LL, Raleigh DP. Synthesis and purification of amyloidogenic peptides. Anal Biochem. 2001;288:76-82.
-
(2001)
Anal Biochem
, vol.288
, pp. 76-82
-
-
Nilsson, M.R.1
Nguyen, L.L.2
Raleigh, D.P.3
-
123
-
-
0025890946
-
Influence of proline residues on protein conformation
-
MacArthur MW, Thornton JM. Influence of proline residues on protein conformation. J Mol Biol. 1991;218:397-412.
-
(1991)
J Mol Biol
, vol.218
, pp. 397-412
-
-
MacArthur, M.W.1
Thornton, J.M.2
-
124
-
-
0028176595
-
Measurement of the beta-sheet-forming propensities of amino acids
-
Minor DL Jr, Kim PS. Measurement of the beta-sheet-forming propensities of amino acids. Nature. 1994;367:660-663.
-
(1994)
Nature
, vol.367
, pp. 660-663
-
-
Minor Jr., D.L.1
Kim, P.S.2
-
125
-
-
0032972592
-
Effects of sequential proline substitutions on amyloid formation by human amylin20-29
-
Moriarty DF, Raleigh DP. Effects of sequential proline substitutions on amyloid formation by human amylin20-29. Biochemistry. 1999;38:1811-1818.
-
(1999)
Biochemistry
, vol.38
, pp. 1811-1818
-
-
Moriarty, D.F.1
Raleigh, D.P.2
-
126
-
-
0030600371
-
Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation
-
Soto C, Kindy MS, Baumann M, et al. Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation. Biochem Biophys Res Commun. 1996;226:672-680.
-
(1996)
Biochem Biophys Res Commun
, vol.226
, pp. 672-680
-
-
Soto, C.1
Kindy, M.S.2
Baumann, M.3
-
127
-
-
0025366838
-
Islet amyloid polypeptide: Pinpointing amino acid residues linked to amyloid fibril formation
-
Westermark P, Engstrom U, Johnson KH, et al. Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation. Proc Natl Acad Sci U S A. 1990;87:5036-5040.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 5036-5040
-
-
Westermark, P.1
Engstrom, U.2
Johnson, K.H.3
-
128
-
-
0024427284
-
Conservation of the sequence of islet amyloid polypeptide in five mammals is consistent with its putative role as an islet hormone
-
Nishi M, Chan SJ, Nagamatsu S, et al. Conservation of the sequence of islet amyloid polypeptide in five mammals is consistent with its putative role as an islet hormone. Proc Natl Acad Sci U S A. 1989;86:5738-5742.
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 5738-5742
-
-
Nishi, M.1
Chan, S.J.2
Nagamatsu, S.3
-
129
-
-
0024400674
-
Sequence divergence in a specific region of islet amyloid polypeptide (IAPP) explains differences in islet amyloid formation between species
-
Betsholtz C, Christmansson L, Engstrom U, et al. Sequence divergence in a specific region of islet amyloid polypeptide (IAPP) explains differences in islet amyloid formation between species. FEBS Lett. 1989;251:261-264.
-
(1989)
FEBS Lett
, vol.251
, pp. 261-264
-
-
Betsholtz, C.1
Christmansson, L.2
Engstrom, U.3
-
130
-
-
0031920985
-
Islet amyloid-associated diabetes in obese A(vy)/a mice expressing human islet amyloid polypeptide
-
Soeller WC, Janson J, Hart SE, et al. Islet amyloid-associated diabetes in obese A(vy)/a mice expressing human islet amyloid polypeptide. Diabetes. 1998;47:743-750.
-
(1998)
Diabetes
, vol.47
, pp. 743-750
-
-
Soeller, W.C.1
Janson, J.2
Hart, S.E.3
-
131
-
-
0028303844
-
Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus
-
Lorenzo A, Razzaboni B, Weir GC, et al. Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus. Nature. 1994;368:756-760.
-
(1994)
Nature
, vol.368
, pp. 756-760
-
-
Lorenzo, A.1
Razzaboni, B.2
Weir, G.C.3
-
132
-
-
0030044018
-
Pore formation by the cytotoxic islet amyloid peptide amylin
-
Mirzabekov TA, Lin MC, Kagan BL. Pore formation by the cytotoxic islet amyloid peptide amylin. J Biol Chem. 1996;271:1988-1992.
-
(1996)
J Biol Chem
, vol.271
, pp. 1988-1992
-
-
Mirzabekov, T.A.1
Lin, M.C.2
Kagan, B.L.3
-
133
-
-
0034632806
-
Islet amyloid and type 2 diabetes mellitus
-
Hoppener JW, Ahren B, Lips CJ. Islet amyloid and type 2 diabetes mellitus. N Engl J Med. 2000;343:411-419.
-
(2000)
N Engl J Med
, vol.343
, pp. 411-419
-
-
Hoppener, J.W.1
Ahren, B.2
Lips, C.J.3
-
134
-
-
0032932422
-
Intracellular amyloidogenesis by human islet amyloid polypeptide induces apoptosis in COS-1 cells
-
Hiddinga HJ, Eberhardt NL. Intracellular amyloidogenesis by human islet amyloid polypeptide induces apoptosis in COS-1 cells. Am J Pathol. 1999;154:1077-1088.
-
(1999)
Am J Pathol
, vol.154
, pp. 1077-1088
-
-
Hiddinga, H.J.1
Eberhardt, N.L.2
-
135
-
-
0028957882
-
Amyloid peptides are toxic via a common oxidative mechanism
-
Schubert D, Behl C, Lesley R, et al. Amyloid peptides are toxic via a common oxidative mechanism. Proc Natl Acad Sci U S A. 1995;92:1989-1993.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 1989-1993
-
-
Schubert, D.1
Behl, C.2
Lesley, R.3
-
136
-
-
0032578777
-
Different sensitivity to the cytotoxic action of IAPP fibrils in two insulin-producing cell lines, HIT-T15 and RINm5F cells
-
Janciauskiene S, Ahren B. Different sensitivity to the cytotoxic action of IAPP fibrils in two insulin-producing cell lines, HIT-T15 and RINm5F cells. Biochem Biophys Res Commun. 1998;251:888-893.
-
(1998)
Biochem Biophys Res Commun
, vol.251
, pp. 888-893
-
-
Janciauskiene, S.1
Ahren, B.2
-
137
-
-
0032800544
-
Induction of apoptosis by human amylin in RINm5F islet beta-cells is associated with enhanced expression of p53 and p21WAF1/CIP1
-
Zhang S, Liu J, Saafi EL, et al. Induction of apoptosis by human amylin in RINm5F islet beta-cells is associated with enhanced expression of p53 and p21WAF1/CIP1. FEBS Lett. 1999;455:315-320.
-
(1999)
FEBS Lett
, vol.455
, pp. 315-320
-
-
Zhang, S.1
Liu, J.2
Saafi, E.L.3
-
138
-
-
0034640372
-
Alzheimer's beta-amyloid, human islet amylin, and prion protein fragment evoke intracellular free calcium elevations by a common mechanism in a hypothalamic GnRH neuronal cell line
-
Kawahara M, Kuroda Y, Arispe N, et al. Alzheimer's beta-amyloid, human islet amylin, and prion protein fragment evoke intracellular free calcium elevations by a common mechanism in a hypothalamic GnRH neuronal cell line. J Biol Chem. 2000;275:14077-14083.
-
(2000)
J Biol Chem
, vol.275
, pp. 14077-14083
-
-
Kawahara, M.1
Kuroda, Y.2
Arispe, N.3
-
140
-
-
0033638450
-
S20G mutant amylin exhibits increased in vitro amyloidogenicity and increased intracellular cytotoxicity compared to wild-type amylin
-
Sakagashira S, Hiddinga HJ, Tateishi K, et al. S20G mutant amylin exhibits increased in vitro amyloidogenicity and increased intracellular cytotoxicity compared to wild-type amylin. Am J Pathol. 2000;157:2101-2109.
-
(2000)
Am J Pathol
, vol.157
, pp. 2101-2109
-
-
Sakagashira, S.1
Hiddinga, H.J.2
Tateishi, K.3
-
141
-
-
0036440981
-
Increased expression and activation of c-Jun contributes to human amylin-induced apoptosis in pancreatic islet beta-cells
-
Zhang S, Liu J, MacGibbon G, et al. Increased expression and activation of c-Jun contributes to human amylin-induced apoptosis in pancreatic islet beta-cells. J Mol Biol. 2002;324:271-285.
-
(2002)
J Mol Biol
, vol.324
, pp. 271-285
-
-
Zhang, S.1
Liu, J.2
MacGibbon, G.3
-
142
-
-
0037167613
-
Protofibrillar islet amyloid polypeptide permeabilizes synthetic vesicles by a pore-like mechanism that may be relevant to type II diabetes
-
Anguiano M, Nowak RJ, Lansbury PT Jr. Protofibrillar islet amyloid polypeptide permeabilizes synthetic vesicles by a pore-like mechanism that may be relevant to type II diabetes. Biochemistry. 2002;41:11338-11343.
-
(2002)
Biochemistry
, vol.41
, pp. 11338-11343
-
-
Anguiano, M.1
Nowak, R.J.2
Lansbury Jr., P.T.3
-
143
-
-
0042822112
-
Increased beta-cell apoptosis prevents adaptive increase in beta-cell mass in mouse model of type 2 diabetes: Evidence for role of islet amyloid formation rather than direct action of amyloid
-
Butler AE, Janson J, Soeller WC, et al. Increased beta-cell apoptosis prevents adaptive increase in beta-cell mass in mouse model of type 2 diabetes: evidence for role of islet amyloid formation rather than direct action of amyloid. Diabetes. 2003;52:2304-2314.
-
(2003)
Diabetes
, vol.52
, pp. 2304-2314
-
-
Butler, A.E.1
Janson, J.2
Soeller, W.C.3
-
144
-
-
0027242013
-
Cosecretion of islet amyloid polypeptide (IAPP) and insulin from isolated rat pancreatic islets following stimulation or inhibition of beta-cell function
-
Stridsberg M, Sandler S, Wilander E. Cosecretion of islet amyloid polypeptide (IAPP) and insulin from isolated rat pancreatic islets following stimulation or inhibition of beta-cell function. Regul Pept. 1993;45:363-370.
-
(1993)
Regul Pept
, vol.45
, pp. 363-370
-
-
Stridsberg, M.1
Sandler, S.2
Wilander, E.3
-
145
-
-
0029023741
-
Effects of arginine on the secretion of insulin and islet amyloid polypeptide in humans
-
Larsson H, Ahren B. Effects of arginine on the secretion of insulin and islet amyloid polypeptide in humans. Pancreas. 1995;11:201-205.
-
(1995)
Pancreas
, vol.11
, pp. 201-205
-
-
Larsson, H.1
Ahren, B.2
-
146
-
-
0033022153
-
Islet amyloid polypeptide and insulin relationship in a longitudinal study of the genetically obese (ob/ob) mouse
-
Leckstrom A, Lundquist I, Ma Z, et al. Islet amyloid polypeptide and insulin relationship in a longitudinal study of the genetically obese (ob/ob) mouse. Pancreas. 1999;18:266-273.
-
(1999)
Pancreas
, vol.18
, pp. 266-273
-
-
Leckstrom, A.1
Lundquist, I.2
Ma, Z.3
-
147
-
-
0026734070
-
Coordinate regulation of amylin and insulin expression in response to hypoglycemia and fasting
-
Alam T, Chen L, Ogawa A, et al. Coordinate regulation of amylin and insulin expression in response to hypoglycemia and fasting. Diabetes. 1992;41:508-514.
-
(1992)
Diabetes
, vol.41
, pp. 508-514
-
-
Alam, T.1
Chen, L.2
Ogawa, A.3
-
148
-
-
0025824715
-
Amylin secretion from the perfused pancreas: Dissociation from insulin and abnormal elevation in insulin-resistant diabetic rats
-
Gedulin B, Cooper GJ, Young AA. Amylin secretion from the perfused pancreas: dissociation from insulin and abnormal elevation in insulin-resistant diabetic rats. Biochem Biophys Res Commun. 1991;180:782-789.
-
(1991)
Biochem Biophys Res Commun
, vol.180
, pp. 782-789
-
-
Gedulin, B.1
Cooper, G.J.2
Young, A.A.3
-
149
-
-
0026354088
-
Islet amyloid polypeptide and insulin secretion from isolated perfused pancreas of fed, fasted, glucose-treated, and dexamethasone-treated rats
-
O'Brien TD, Westermark P, Johnson KH. Islet amyloid polypeptide and insulin secretion from isolated perfused pancreas of fed, fasted, glucose-treated, and dexamethasone-treated rats. Diabetes. 1991;40:1701-1706.
-
(1991)
Diabetes
, vol.40
, pp. 1701-1706
-
-
O'Brien, T.D.1
Westermark, P.2
Johnson, K.H.3
-
150
-
-
0029742232
-
Treatment with growth hormone and dexamethasone in mice transgenic for human islet amyloid polypeptide causes islet amyloidosis and beta-cell dysfunction
-
Couce M, Kane LA, O'Brien TD, et al. Treatment with growth hormone and dexamethasone in mice transgenic for human islet amyloid polypeptide causes islet amyloidosis and beta-cell dysfunction. Diabetes. 1996;45:1094-1101.
-
(1996)
Diabetes
, vol.45
, pp. 1094-1101
-
-
Couce, M.1
Kane, L.A.2
O'Brien, T.D.3
-
151
-
-
0030975858
-
Dissociated secretion of islet amyloid polypeptide and insulin in serum-free culture media conditioned by human pancreatic adenocarcinoma cell lines
-
Wang F, Larsson J, Abdiu A, et al. Dissociated secretion of islet amyloid polypeptide and insulin in serum-free culture media conditioned by human pancreatic adenocarcinoma cell lines. Int J Pancreatol. 1997;21:157-164.
-
(1997)
Int J Pancreatol
, vol.21
, pp. 157-164
-
-
Wang, F.1
Larsson, J.2
Abdiu, A.3
-
152
-
-
0031962182
-
Pancreatic cancer cells selectively stimulate islet beta cells to secrete amylin
-
Ding X, Flatt PR, Permert J, et al. Pancreatic cancer cells selectively stimulate islet beta cells to secrete amylin. Gastroenterology. 1998;114:130-138.
-
(1998)
Gastroenterology
, vol.114
, pp. 130-138
-
-
Ding, X.1
Flatt, P.R.2
Permert, J.3
-
153
-
-
0026512386
-
Plasma islet amyloid polypeptide levels in obesity, impaired glucose tolerance and non-insulin-dependent diabetes mellitus
-
Enoki S, Mitsukawa T, Takemura J, et al. Plasma islet amyloid polypeptide levels in obesity, impaired glucose tolerance and non-insulin-dependent diabetes mellitus. Diabetes Res Clin Pract. 1992;15:97-102.
-
(1992)
Diabetes Res Clin Pract
, vol.15
, pp. 97-102
-
-
Enoki, S.1
Mitsukawa, T.2
Takemura, J.3
-
154
-
-
0026556922
-
Islet amyloid polypeptide (IAPP) secretion from islet cells and its plasma concentration in patients with non-insulin-dependent diabetes mellitus
-
Hanabusa T, Kubo K, Oki C, et al. Islet amyloid polypeptide (IAPP) secretion from islet cells and its plasma concentration in patients with non-insulin-dependent diabetes mellitus. Diabetes Res Clin Pract. 1992;15:89-96.
-
(1992)
Diabetes Res Clin Pract
, vol.15
, pp. 89-96
-
-
Hanabusa, T.1
Kubo, K.2
Oki, C.3
-
155
-
-
0028054783
-
Islet amyloid polypeptide in patients with pancreatic cancer and diabetes
-
Permert J, Larsson J, Westermark GT, et al. Islet amyloid polypeptide in patients with pancreatic cancer and diabetes. N Engl J Med. 1994;330:313-318.
-
(1994)
N Engl J Med
, vol.330
, pp. 313-318
-
-
Permert, J.1
Larsson, J.2
Westermark, G.T.3
-
156
-
-
0027952912
-
Role of islet amyloid polypeptide secretion in insulin-resistant humans
-
Kautzky-Willer A, Thomaseth K, Pacini G, et al. Role of islet amyloid polypeptide secretion in insulin-resistant humans. Diabetologia. 1994;37:188-194.
-
(1994)
Diabetologia
, vol.37
, pp. 188-194
-
-
Kautzky-Willer, A.1
Thomaseth, K.2
Pacini, G.3
-
157
-
-
0027447093
-
Influence of islet amyloid polypeptide and the 8-37 fragment of islet amyloid polypeptide on insulin release from perifused rat islets
-
Wang ZL, Bennet WM, Ghatei MA, et al. Influence of islet amyloid polypeptide and the 8-37 fragment of islet amyloid polypeptide on insulin release from perifused rat islets. Diabetes. 1993;42:330-335.
-
(1993)
Diabetes
, vol.42
, pp. 330-335
-
-
Wang, Z.L.1
Bennet, W.M.2
Ghatei, M.A.3
-
158
-
-
0028207502
-
Amylin (islet amyloid polypeptide) inhibition of insulin release in the perfused rat pancreas: Implication of the adenylate cyclase/cAMP system
-
Silvestre RA, Salas M, Garcia-Hermida O, et al. Amylin (islet amyloid polypeptide) inhibition of insulin release in the perfused rat pancreas: implication of the adenylate cyclase/cAMP system. Regul Pept. 1994;50:193-199.
-
(1994)
Regul Pept
, vol.50
, pp. 193-199
-
-
Silvestre, R.A.1
Salas, M.2
Garcia-Hermida, O.3
-
159
-
-
0027953075
-
Islet amyloid polypeptide inhibits insulin secretion in conscious rats
-
Furnsinn C, Leuvenink H, Roden M, et al. Islet amyloid polypeptide inhibits insulin secretion in conscious rats. Am J Physiol. 1994;267:E300-E305.
-
(1994)
Am J Physiol
, vol.267
-
-
Furnsinn, C.1
Leuvenink, H.2
Roden, M.3
-
160
-
-
0027991946
-
Chronic exposure of cultured rat pancreatic islets to elevated concentrations of islet amyloid polypeptide (IAPP) causes a decrease in islet DNA content and medium insulin accumulation
-
Sandler S, Stridsberg M. Chronic exposure of cultured rat pancreatic islets to elevated concentrations of islet amyloid polypeptide (IAPP) causes a decrease in islet DNA content and medium insulin accumulation. Regul Pept. 1994;53:103-109.
-
(1994)
Regul Pept
, vol.53
, pp. 103-109
-
-
Sandler, S.1
Stridsberg, M.2
-
161
-
-
0032544715
-
Increased insulin secretion and glucose tolerance in mice lacking islet amyloid polypeptide (amylin)
-
Gebre-Medhin S, Mulder H, Pekny M, et al. Increased insulin secretion and glucose tolerance in mice lacking islet amyloid polypeptide (amylin). Biochem Biophys Res Commun. 1998;250:271-277.
-
(1998)
Biochem Biophys Res Commun
, vol.250
, pp. 271-277
-
-
Gebre-Medhin, S.1
Mulder, H.2
Pekny, M.3
-
162
-
-
0033146803
-
IAPP as a regulator of glucose homeostasis and pancreatic hormone secretion
-
Karlsson E. IAPP as a regulator of glucose homeostasis and pancreatic hormone secretion [review]. Int J Mol Med. 1999;3:577-584.
-
(1999)
Int J Mol Med
, vol.3
, pp. 577-584
-
-
Karlsson, E.1
-
163
-
-
0041755815
-
The amylin analog pramlintide improves glycemic control and reduces postprandial glucagon concentrations in patients with type 1 diabetes mellitus
-
Nyholm B, Orskov L, Hove KY, et al. The amylin analog pramlintide improves glycemic control and reduces postprandial glucagon concentrations in patients with type 1 diabetes mellitus. Metabolism. 1999;48:935-941.
-
(1999)
Metabolism
, vol.48
, pp. 935-941
-
-
Nyholm, B.1
Orskov, L.2
Hove, K.Y.3
-
164
-
-
0343831910
-
Selective amylin inhibition of the glucagon response to arginine is extrinsic to the pancreas
-
Silvestre RA, Rodriguez-Gallardo J, Jodka C, et al. Selective amylin inhibition of the glucagon response to arginine is extrinsic to the pancreas. Am J Physiol Endocrinol Metab. 2001;280:E443-E449.
-
(2001)
Am J Physiol Endocrinol Metab
, vol.280
-
-
Silvestre, R.A.1
Rodriguez-Gallardo, J.2
Jodka, C.3
-
166
-
-
0029001899
-
Dose-dependent elevation of cyclic AMP, activation of glycogen phosphorylase, and release of lactate by amylin in rat skeletal muscle
-
Pittner R, Beaumont K, Young A, et al. Dose-dependent elevation of cyclic AMP, activation of glycogen phosphorylase, and release of lactate by amylin in rat skeletal muscle. Biochim Biophys Acta. 1995;1267:75-82.
-
(1995)
Biochim Biophys Acta
, vol.1267
, pp. 75-82
-
-
Pittner, R.1
Beaumont, K.2
Young, A.3
-
167
-
-
0032810881
-
Stimulation of both aerobic glycolysis and Na(+)-K(+)-ATPase activity in skeletal muscle by epinephrine or amylin
-
James JH, Wagner KR, King JK, et al. Stimulation of both aerobic glycolysis and Na(+)-K(+)-ATPase activity in skeletal muscle by epinephrine or amylin. Am J Physiol. 1999;277:E176-E186.
-
(1999)
Am J Physiol
, vol.277
-
-
James, J.H.1
Wagner, K.R.2
King, J.K.3
-
168
-
-
0033841313
-
Effects of amylin and other peptide hormones on Na+-K+ transport and contractility in rat skeletal muscle
-
Clausen T. Effects of amylin and other peptide hormones on Na+-K+ transport and contractility in rat skeletal muscle. J Physiol. 2000;527:121-130.
-
(2000)
J Physiol
, vol.527
, pp. 121-130
-
-
Clausen, T.1
-
169
-
-
0028884920
-
Differential antagonism of amylin's metabolic and vascular actions with amylin receptor antagonists
-
Beaumont K, Moore CX, Pittner RA, et al. Differential antagonism of amylin's metabolic and vascular actions with amylin receptor antagonists. Can J Physiol Pharmacol. 1995;73:1025-1029.
-
(1995)
Can J Physiol Pharmacol
, vol.73
, pp. 1025-1029
-
-
Beaumont, K.1
Moore, C.X.2
Pittner, R.A.3
-
170
-
-
0030728818
-
Effect of islet amyloid polypeptide on somatostatin inhibition of insulin secretion from isolated rat pancreatic islets
-
Wang F, Westermark G, Gasslander T, et al. Effect of islet amyloid polypeptide on somatostatin inhibition of insulin secretion from isolated rat pancreatic islets. Regul Pept. 1997;72:61-67.
-
(1997)
Regul Pept
, vol.72
, pp. 61-67
-
-
Wang, F.1
Westermark, G.2
Gasslander, T.3
-
171
-
-
0026825703
-
8-37hCGRP, an amylin receptor antagonist, enhances the insulin response and perturbs the glucose response to infused arginine in anesthetized rats
-
Young AA, Carlo P, Rink TJ, et al. 8-37hCGRP, an amylin receptor antagonist, enhances the insulin response and perturbs the glucose response to infused arginine in anesthetized rats. Mol Cell Endocrinol. 1992;84:R1-R5.
-
(1992)
Mol Cell Endocrinol
, vol.84
-
-
Young, A.A.1
Carlo, P.2
Rink, T.J.3
-
172
-
-
0032946303
-
Islet amyloid polypeptide tonally inhibits beta-, alpha-, and delta-cell secretion in isolated rat pancreatic islets
-
Wang F, Adrian TE, Westermark GT, et al. Islet amyloid polypeptide tonally inhibits beta-, alpha-, and delta-cell secretion in isolated rat pancreatic islets. Am J Physiol. 1999;276:E19-E24.
-
(1999)
Am J Physiol
, vol.276
-
-
Wang, F.1
Adrian, T.E.2
Westermark, G.T.3
-
173
-
-
0026771921
-
Very high concentrations of islet amyloid polypeptide are necessary to alter the insulin response to intravenous glucose in man
-
Bretherton-Watt D, Gilbey SG, Ghatei MA, et al. Very high concentrations of islet amyloid polypeptide are necessary to alter the insulin response to intravenous glucose in man. J Clin Endocrinol Metab. 1992;74:1032-1035.
-
(1992)
J Clin Endocrinol Metab
, vol.74
, pp. 1032-1035
-
-
Bretherton-Watt, D.1
Gilbey, S.G.2
Ghatei, M.A.3
-
174
-
-
0036250177
-
Role of amylin in insulin secretion and action in humans: Antagonist studies across the spectrum of insulin sensitivity
-
Mather KJ, Paradisi G, Learning R, et al. Role of amylin in insulin secretion and action in humans: antagonist studies across the spectrum of insulin sensitivity. Diabetes Metab Res Rev. 2002;18:118-126.
-
(2002)
Diabetes Metab Res Rev
, vol.18
, pp. 118-126
-
-
Mather, K.J.1
Paradisi, G.2
Learning, R.3
-
175
-
-
0027470090
-
Formation of islet amyloid from islet amyloid polypeptide
-
Clark A, de Koning EJ, Morris JF. Formation of islet amyloid from islet amyloid polypeptide. Biochem Soc Trans. 1993;21:169-173.
-
(1993)
Biochem Soc Trans
, vol.21
, pp. 169-173
-
-
Clark, A.1
De Koning, E.J.2
Morris, J.F.3
-
176
-
-
0030478641
-
Islet amyloid polypeptide and insulin gene expression are regulated in parallel by glucose in vivo in rats
-
Mulder H, Ahren B, Sundler F. Islet amyloid polypeptide and insulin gene expression are regulated in parallel by glucose in vivo in rats. Am J Physiol. 1996;271:E1008-E1014.
-
(1996)
Am J Physiol
, vol.271
-
-
Mulder, H.1
Ahren, B.2
Sundler, F.3
-
177
-
-
0031589850
-
Signals related to glucose metabolism regulate islet amyloid polypeptide (IAPP) gene expression in human pancreatic islets
-
Gasa R, Gomis R, Casamitjana R, et al. Signals related to glucose metabolism regulate islet amyloid polypeptide (IAPP) gene expression in human pancreatic islets. Regul Pept. 1997;68:99-104.
-
(1997)
Regul Pept
, vol.68
, pp. 99-104
-
-
Gasa, R.1
Gomis, R.2
Casamitjana, R.3
-
178
-
-
0024805953
-
Altered islet amyloid polypeptide (amylin) gene expression in rat models of diabetes
-
Bretherton-Watt D, Ghatei MA, Bloom SR, et al. Altered islet amyloid polypeptide (amylin) gene expression in rat models of diabetes. Diabetologia. 1989;32:881-883.
-
(1989)
Diabetologia
, vol.32
, pp. 881-883
-
-
Bretherton-Watt, D.1
Ghatei, M.A.2
Bloom, S.R.3
-
180
-
-
0035086993
-
High glucose concentration favors the selective secretion of islet amyloid polypeptide through a constitutive secretory pathway in human pancreatic islets
-
Gasa R, Gomis R, Casamitjana R, et al. High glucose concentration favors the selective secretion of islet amyloid polypeptide through a constitutive secretory pathway in human pancreatic islets. Pancreas. 2001;22:307-310.
-
(2001)
Pancreas
, vol.22
, pp. 307-310
-
-
Gasa, R.1
Gomis, R.2
Casamitjana, R.3
-
181
-
-
0032896436
-
Prolonged exposure of pancreatic beta cells to raised glucose concentrations results in increased cellular content of islet amyloid polypeptide precursors
-
Hou X, Ling Z, Quartier E, et al. Prolonged exposure of pancreatic beta cells to raised glucose concentrations results in increased cellular content of islet amyloid polypeptide precursors. Diabetologia. 1999;42:188-194.
-
(1999)
Diabetologia
, vol.42
, pp. 188-194
-
-
Hou, X.1
Ling, Z.2
Quartier, E.3
-
182
-
-
0026541689
-
Hyperamylinemia, hyperinsulinemia, and insulin resistance in genetically obese LA/N-cp rats
-
Huang HJ, Young AA, Koda JE, et al. Hyperamylinemia, hyperinsulinemia, and insulin resistance in genetically obese LA/N-cp rats. Hypertension. 1992;19:I101-I109.
-
(1992)
Hypertension
, vol.19
-
-
Huang, H.J.1
Young, A.A.2
Koda, J.E.3
-
183
-
-
0028954799
-
Non-parallelism of islet amyloid polypeptide (amylin) and insulin gene expression in rats islets following dexamethasone treatment
-
Mulder H, Ahren B, Stridsberg M, et al. Non-parallelism of islet amyloid polypeptide (amylin) and insulin gene expression in rats islets following dexamethasone treatment. Diabetologia. 1995;38:395-402.
-
(1995)
Diabetologia
, vol.38
, pp. 395-402
-
-
Mulder, H.1
Ahren, B.2
Stridsberg, M.3
-
184
-
-
0031055439
-
Differential effect of insulin treatment on islet amyloid polypeptide (amylin) and insulin gene expression in streptozotocin-induced diabetes in rats
-
Mulder H, Ahren B, Sundler F. Differential effect of insulin treatment on islet amyloid polypeptide (amylin) and insulin gene expression in streptozotocin-induced diabetes in rats. J Endocrinol. 1997;152:495-501.
-
(1997)
J Endocrinol
, vol.152
, pp. 495-501
-
-
Mulder, H.1
Ahren, B.2
Sundler, F.3
-
185
-
-
0026519747
-
Feedback inhibition of insulin gene expression by insulin
-
Koranyi L, James DE, Kraegen EW, et al. Feedback inhibition of insulin gene expression by insulin. J Clin Invest. 1992;89:432-436.
-
(1992)
J Clin Invest
, vol.89
, pp. 432-436
-
-
Koranyi, L.1
James, D.E.2
Kraegen, E.W.3
-
186
-
-
0026642430
-
Developmental regulation of amylin and insulin-gene expression in lean (Fa/Fa) and obese (fa/fa) Zucker rats
-
Koranyi L, Tanizawa Y, Penicaud L, et al. Developmental regulation of amylin and insulin-gene expression in lean (Fa/Fa) and obese (fa/fa) Zucker rats. Diabetes. 1992;41:685-690.
-
(1992)
Diabetes
, vol.41
, pp. 685-690
-
-
Koranyi, L.1
Tanizawa, Y.2
Penicaud, L.3
-
187
-
-
0028929321
-
Age-related changes in pancreatic islet cell gene expression
-
Giddings SJ, Carnaghi LR, Mooradian AD. Age-related changes in pancreatic islet cell gene expression. Metabolism. 1995;44:320-324.
-
(1995)
Metabolism
, vol.44
, pp. 320-324
-
-
Giddings, S.J.1
Carnaghi, L.R.2
Mooradian, A.D.3
-
188
-
-
0035195537
-
Glucose and forskolin regulate IAPP gene expression through different signal transduction pathways
-
Ding WQ, Holicky E, Miller LJ. Glucose and forskolin regulate IAPP gene expression through different signal transduction pathways. Am J Physiol Endocrinol Metab. 2001;281:E938-E945.
-
(2001)
Am J Physiol Endocrinol Metab
, vol.281
-
-
Ding, W.Q.1
Holicky, E.2
Miller, L.J.3
-
189
-
-
0242663404
-
Amylin gene expression mediated by cAMP/PKA and transcription factors HNF-1 and NFY
-
Cluck MW, Murphy LO, Olson J, et al. Amylin gene expression mediated by cAMP/PKA and transcription factors HNF-1 and NFY. Mol Cell Endocrinol. 2003;210:63-75.
-
(2003)
Mol Cell Endocrinol
, vol.210
, pp. 63-75
-
-
Cluck, M.W.1
Murphy, L.O.2
Olson, J.3
-
190
-
-
0019979206
-
Biosynthesis of rat insulins I and II: Evidence for differential expression of the two genes
-
Kakita K, Giddings S, Permutt MA. Biosynthesis of rat insulins I and II: evidence for differential expression of the two genes. Proc Natl Acad Sci U S A. 1982;79:2803-2807.
-
(1982)
Proc Natl Acad Sci U S A
, vol.79
, pp. 2803-2807
-
-
Kakita, K.1
Giddings, S.2
Permutt, M.A.3
-
191
-
-
0029095353
-
The insulin gene promoter. A simplified nomenclature
-
German M, Ashcroft S, Docherty K, et al. The insulin gene promoter. A simplified nomenclature. Diabetes. 1995;44:1002-1004.
-
(1995)
Diabetes
, vol.44
, pp. 1002-1004
-
-
German, M.1
Ashcroft, S.2
Docherty, K.3
-
192
-
-
0024025198
-
Systematic binding analysis of the insulin gene transcription control region: Insulin and immunoglobulin enhancers utilize similar transactivators
-
Moss LG, Moss JB, Rutter WJ. Systematic binding analysis of the insulin gene transcription control region: insulin and immunoglobulin enhancers utilize similar transactivators. Mol Cell Biol. 1988;8:2620-2627.
-
(1988)
Mol Cell Biol
, vol.8
, pp. 2620-2627
-
-
Moss, L.G.1
Moss, J.B.2
Rutter, W.J.3
-
193
-
-
2642628564
-
A beta-cell-specific protein binds to the two major regulatory sequences of the insulin gene enhancer
-
Ohlsson H, Karlsson O, Edlund T. A beta-cell-specific protein binds to the two major regulatory sequences of the insulin gene enhancer. Proc Natl Acad Sci U S A. 1988;85:4228-4231.
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 4228-4231
-
-
Ohlsson, H.1
Karlsson, O.2
Edlund, T.3
-
194
-
-
0024494832
-
Individual protein-binding domains of the insulin gene enhancer positively activate beta-cell-specific transcription
-
Karlsson O, Walker MD, Rutter WJ, et al. Individual protein-binding domains of the insulin gene enhancer positively activate beta-cell-specific transcription. Mol Cell Biol. 1989;9:823-827.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 823-827
-
-
Karlsson, O.1
Walker, M.D.2
Rutter, W.J.3
-
195
-
-
0026386775
-
Novel insulin promoter- and enhancer-binding proteins that discriminate between pancreatic alpha- and beta-cells
-
Ohlsson H, Thor S, Edlund T. Novel insulin promoter- and enhancer-binding proteins that discriminate between pancreatic alpha- and beta-cells. Mol Endocrinol. 1991;5:897-904.
-
(1991)
Mol Endocrinol
, vol.5
, pp. 897-904
-
-
Ohlsson, H.1
Thor, S.2
Edlund, T.3
-
196
-
-
0026016780
-
Two related helix-loop-helix proteins participate in separate cell-specific complexes that bind the insulin enhancer
-
German MS, Blanar MA, Nelson C, et al. Two related helix-loop-helix proteins participate in separate cell-specific complexes that bind the insulin enhancer. Mol Endocrinol. 1991;5:292-299.
-
(1991)
Mol Endocrinol
, vol.5
, pp. 292-299
-
-
German, M.S.1
Blanar, M.A.2
Nelson, C.3
-
197
-
-
0028050241
-
Isolation and characterization of a novel transcription factor that binds to and activates insulin control element-mediated expression
-
Robinson GL, Cordle SR, Henderson E, et al. Isolation and characterization of a novel transcription factor that binds to and activates insulin control element-mediated expression. Mol Cell Biol. 1994;14:6704-6714.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 6704-6714
-
-
Robinson, G.L.1
Cordle, S.R.2
Henderson, E.3
-
198
-
-
0032493623
-
Differential regulation of the glucagon and insulin I gene promoters by the basic helix-loop-helix transcription factors E47 and BETA2
-
Dumonteil E, Laser B, Constant I, et al. Differential regulation of the glucagon and insulin I gene promoters by the basic helix-loop-helix transcription factors E47 and BETA2. J Biol Chem. 1998;273:19945-19954.
-
(1998)
J Biol Chem
, vol.273
, pp. 19945-19954
-
-
Dumonteil, E.1
Laser, B.2
Constant, I.3
-
199
-
-
0028831207
-
The Pan basic helix-loop-helix proteins are required for insulin gene expression
-
Vierra CA, Nelson C. The Pan basic helix-loop-helix proteins are required for insulin gene expression. Mol Endocrinol. 1995;9:64-71.
-
(1995)
Mol Endocrinol
, vol.9
, pp. 64-71
-
-
Vierra, C.A.1
Nelson, C.2
-
200
-
-
0026602931
-
The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical beta-cell nuclear complexes
-
German MS, Moss LG, Wang J, et al. The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical beta-cell nuclear complexes. Mol Cell Biol. 1992;12:1777-1788.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 1777-1788
-
-
German, M.S.1
Moss, L.G.2
Wang, J.3
-
201
-
-
0027384997
-
IPF1, a homeodomain-containing transactivator of the insulin gene
-
Ohlsson H, Karlsson K, Edlund T. IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO J. 1993;12:4251-4259.
-
(1993)
EMBO J
, vol.12
, pp. 4251-4259
-
-
Ohlsson, H.1
Karlsson, K.2
Edlund, T.3
-
202
-
-
0028567837
-
Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1
-
Peers B, Leonard J, Sharma S, et al. Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1. Mol Endocrinol. 1994;8:1798-1806.
-
(1994)
Mol Endocrinol
, vol.8
, pp. 1798-1806
-
-
Peers, B.1
Leonard, J.2
Sharma, S.3
-
203
-
-
0030846574
-
The p38/reactivating kinase mitogen-activated protein kinase cascade mediates the activation of the transcription factor insulin upstream factor 1 and insulin gene transcription by high glucose in pancreatic beta-cells
-
Macfarlane WM, Smith SB, James RF, et al. The p38/reactivating kinase mitogen-activated protein kinase cascade mediates the activation of the transcription factor insulin upstream factor 1 and insulin gene transcription by high glucose in pancreatic beta-cells. J Biol Chem. 1997;272:20936-20944.
-
(1997)
J Biol Chem
, vol.272
, pp. 20936-20944
-
-
Macfarlane, W.M.1
Smith, S.B.2
James, R.F.3
-
204
-
-
0034049069
-
Glucose modulation of insulin mRNA levels is dependent on transcription factor PDX-1 and occurs independently of changes in intracellular Ca2+
-
Macfarlane WM, Shepherd RM, Cosgrove KE, et al. Glucose modulation of insulin mRNA levels is dependent on transcription factor PDX-1 and occurs independently of changes in intracellular Ca2+. Diabetes. 2000;49:418-423.
-
(2000)
Diabetes
, vol.49
, pp. 418-423
-
-
Macfarlane, W.M.1
Shepherd, R.M.2
Cosgrove, K.E.3
-
205
-
-
0028149890
-
Insulin-promoter-factor 1 is required for pancreas development in mice
-
Jonsson J, Carlsson L, Edlund T, et al. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature. 1994;371:606-609.
-
(1994)
Nature
, vol.371
, pp. 606-609
-
-
Jonsson, J.1
Carlsson, L.2
Edlund, T.3
-
206
-
-
0029166081
-
The homeodomain protein IPF-1/STF-1 is expressed in a subset of islet cells and promotes rat insulin 1 gene expression dependent on an intact E1 helix-loop-helix factor binding site
-
Serup P, Petersen HV, Pedersen EE, et al. The homeodomain protein IPF-1/STF-1 is expressed in a subset of islet cells and promotes rat insulin 1 gene expression dependent on an intact E1 helix-loop-helix factor binding site. Biochem J. 1995;310:997-1003.
-
(1995)
Biochem J
, vol.310
, pp. 997-1003
-
-
Serup, P.1
Petersen, H.V.2
Pedersen, E.E.3
-
207
-
-
0035084164
-
Glucagon-like peptide 1 induces differentiation of islet duodenal homeobox-1-positive pancreatic ductal cells into insulin-secreting cells
-
Hui H, Wright C, Perfetti R. Glucagon-like peptide 1 induces differentiation of islet duodenal homeobox-1-positive pancreatic ductal cells into insulin-secreting cells. Diabetes. 2001;50:785-796.
-
(2001)
Diabetes
, vol.50
, pp. 785-796
-
-
Hui, H.1
Wright, C.2
Perfetti, R.3
-
208
-
-
0027154077
-
Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters
-
Melloul D, Ben-Neriah Y, Cerasi E. Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters. Proc Natl Acad Sci U S A. 1993;90:3865-3869.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 3865-3869
-
-
Melloul, D.1
Ben-Neriah, Y.2
Cerasi, E.3
-
209
-
-
0030447883
-
Purification of the beta-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells
-
Marshak S, Totary H, Cerasi E, et al. Purification of the beta-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells. Proc Natl Acad Sci U S A. 1996:93:15057-15062.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 15057-15062
-
-
Marshak, S.1
Totary, H.2
Cerasi, E.3
-
210
-
-
0345073682
-
Induction of Mad expression leads to augmentation of insulin gene transcription
-
Patane G, Kaneto H, Toschi E, et al. Induction of Mad expression leads to augmentation of insulin gene transcription. Biochem Biophys Res Commun. 2003;303:1199-1208.
-
(2003)
Biochem Biophys Res Commun
, vol.303
, pp. 1199-1208
-
-
Patane, G.1
Kaneto, H.2
Toschi, E.3
-
211
-
-
0037066726
-
Induction of c-Myc expression suppresses insulin gene transcription by inhibiting NeuroD/BETA2-mediated transcriptional activation
-
Kaneto H, Sharma A, Suzuma K, et al. Induction of c-Myc expression suppresses insulin gene transcription by inhibiting NeuroD/BETA2-mediated transcriptional activation. J Biol Chem. 2002;277:12998-13006.
-
(2002)
J Biol Chem
, vol.277
, pp. 12998-13006
-
-
Kaneto, H.1
Sharma, A.2
Suzuma, K.3
-
212
-
-
0023477391
-
A mutational analysis of the insulin gene transcription control region: Expression in beta cells is dependent on two related sequences within the enhancer
-
Karlsson O, Edlund T, Moss JB, et al. A mutational analysis of the insulin gene transcription control region: expression in beta cells is dependent on two related sequences within the enhancer. Proc Natl Acad Sci U S A. 1987;84:8819-8823.
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 8819-8823
-
-
Karlsson, O.1
Edlund, T.2
Moss, J.B.3
-
213
-
-
0034602155
-
Transcriptional and translational regulation of beta-cell differentiation factor Nkx6.1
-
Watada H, Mirmira RG, Leung J, et al. Transcriptional and translational regulation of beta-cell differentiation factor Nkx6.1. J Biol Chem. 2000;275:34224-34230.
-
(2000)
J Biol Chem
, vol.275
, pp. 34224-34230
-
-
Watada, H.1
Mirmira, R.G.2
Leung, J.3
-
214
-
-
0026439947
-
Pur-1, a zinc-finger protein that binds to purine-rich sequences, transactivates an insulin promoter in heterologous cells
-
Kennedy GC, Rutter WJ. Pur-1, a zinc-finger protein that binds to purine-rich sequences, transactivates an insulin promoter in heterologous cells. Proc Natl Acad Sci U S A. 1992;89:11498-11502.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 11498-11502
-
-
Kennedy, G.C.1
Rutter, W.J.2
-
215
-
-
0028077338
-
Distinct properties of the cAMP-responsive element of the rat insulin I gene
-
Oetjen E, Diedrich T, Eggers A, et al. Distinct properties of the cAMP-responsive element of the rat insulin I gene. J Biol Chem. 1994;269:27036-27044.
-
(1994)
J Biol Chem
, vol.269
, pp. 27036-27044
-
-
Oetjen, E.1
Diedrich, T.2
Eggers, A.3
-
216
-
-
0041970072
-
Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells
-
Matsuoka TA, Zhao L, Artner I, et al. Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells. Mol Cell Biol. 2003;23:6049-6062.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 6049-6062
-
-
Matsuoka, T.A.1
Zhao, L.2
Artner, I.3
-
217
-
-
0024596435
-
Mutagenesis of the rat insulin II 5′-flanking region defines sequences important for expression in HIT cells
-
Crowe DT, Tsai MJ. Mutagenesis of the rat insulin II 5′-flanking region defines sequences important for expression in HIT cells. Mol Cell Biol. 1989;9:1784-1789.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 1784-1789
-
-
Crowe, D.T.1
Tsai, M.J.2
-
218
-
-
0025994835
-
Cell-specific and ubiquitous factors are responsible for the enhancer activity of the rat insulin II gene
-
Shieh SY, Tsai MJ. Cell-specific and ubiquitous factors are responsible for the enhancer activity of the rat insulin II gene. J Biol Chem. 1991;266:16708-16714.
-
(1991)
J Biol Chem
, vol.266
, pp. 16708-16714
-
-
Shieh, S.Y.1
Tsai, M.J.2
-
219
-
-
0027960493
-
Two distinct class a helix-loop-helix transcription factors, E2A and BETA1, form separate DNA binding complexes on the insulin gene e box
-
Peyton M, Moss LG, Tsai MJ. Two distinct class A helix-loop-helix transcription factors, E2A and BETA1, form separate DNA binding complexes on the insulin gene E box. J Biol Chem. 1994;269:25936-25941.
-
(1994)
J Biol Chem
, vol.269
, pp. 25936-25941
-
-
Peyton, M.1
Moss, L.G.2
Tsai, M.J.3
-
220
-
-
0031790356
-
Differential expression of rat insulin I and II messenger ribonucleic acid after prolonged exposure of islet beta-cells to elevated glucose levels
-
Ling Z, Heimberg H, Foriers A, et al. Differential expression of rat insulin I and II messenger ribonucleic acid after prolonged exposure of islet beta-cells to elevated glucose levels. Endocrinology. 1998;139:491-495.
-
(1998)
Endocrinology
, vol.139
, pp. 491-495
-
-
Ling, Z.1
Heimberg, H.2
Foriers, A.3
-
221
-
-
1842292177
-
Pancreatic beta-cell-specific repression of insulin gene transcription by CCAAT/enhancer-binding protein beta. Inhibitory interactions with basic helix-loop-helix transcription factor E47
-
Lu M, Seufert J, Habener JF. Pancreatic beta-cell-specific repression of insulin gene transcription by CCAAT/enhancer-binding protein beta. Inhibitory interactions with basic helix-loop-helix transcription factor E47. J Biol Chem. 1997;272:28349-28359.
-
(1997)
J Biol Chem
, vol.272
, pp. 28349-28359
-
-
Lu, M.1
Seufert, J.2
Habener, J.F.3
-
222
-
-
0033454003
-
Inhibitory effect of pax4 on the human insulin and islet amyloid polypeptide (IAPP) promoters
-
Campbell SC, Cragg H, Elrick LJ, et al. Inhibitory effect of pax4 on the human insulin and islet amyloid polypeptide (IAPP) promoters. FEBS Lett. 1999;463:53-57.
-
(1999)
FEBS Lett
, vol.463
, pp. 53-57
-
-
Campbell, S.C.1
Cragg, H.2
Elrick, L.J.3
-
223
-
-
0035207610
-
Pax4 regulatory elements mediate beta cell specific expression in the pancreas
-
Brink C, Chowdhury K, Gruss P. Pax4 regulatory elements mediate beta cell specific expression in the pancreas. Mech Dev. 2001;100:37-43.
-
(2001)
Mech Dev
, vol.100
, pp. 37-43
-
-
Brink, C.1
Chowdhury, K.2
Gruss, P.3
-
224
-
-
0034711279
-
Autoregulation and maturity onset diabetes of the young transcription factors control the human PAX4 promoter
-
Smith SB, Watada H, Scheel DW, et al. Autoregulation and maturity onset diabetes of the young transcription factors control the human PAX4 promoter. J Biol Chem. 2000;275:36910-36919.
-
(2000)
J Biol Chem
, vol.275
, pp. 36910-36919
-
-
Smith, S.B.1
Watada, H.2
Scheel, D.W.3
-
225
-
-
1842330860
-
Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development
-
Sander M, Neubuser A, Kalamaras J, et al. Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development. Genes Dev. 1997;11:1662-1673.
-
(1997)
Genes Dev
, vol.11
, pp. 1662-1673
-
-
Sander, M.1
Neubuser, A.2
Kalamaras, J.3
-
226
-
-
0035054637
-
Glucose and other insulin secretagogues induce, rather than inhibit, expression of Id-1 and Id-3 in pancreatic islet beta cells
-
Wice BM, Bernal-Mizrachi E, Permutt MA. Glucose and other insulin secretagogues induce, rather than inhibit, expression of Id-1 and Id-3 in pancreatic islet beta cells. Diabetologia. 2001;44:453-463.
-
(2001)
Diabetologia
, vol.44
, pp. 453-463
-
-
Wice, B.M.1
Bernal-Mizrachi, E.2
Permutt, M.A.3
-
227
-
-
0036189610
-
Syntaxin- 3 and syntaxin-1A inhibit L-type calcium channel activity, insulin biosynthesis and exocytosis in beta-cell lines
-
Kang Y, Huang X, Pasyk EA, et al. Syntaxin- 3 and syntaxin-1A inhibit L-type calcium channel activity, insulin biosynthesis and exocytosis in beta-cell lines. Diabetologia. 2002;45:231-241.
-
(2002)
Diabetologia
, vol.45
, pp. 231-241
-
-
Kang, Y.1
Huang, X.2
Pasyk, E.A.3
-
228
-
-
0025010183
-
Islet amyloid polypeptide: Structure and upstream sequences of the IAPP gene in rat and man
-
van Mansfeld AD, Mosselman S, Hoppener JW, et al. Islet amyloid polypeptide: structure and upstream sequences of the IAPP gene in rat and man. Biochim Biophys Acta. 1990;1087:235-240.
-
(1990)
Biochim Biophys Acta
, vol.1087
, pp. 235-240
-
-
Van Mansfeld, A.D.1
Mosselman, S.2
Hoppener, J.W.3
-
229
-
-
0027248698
-
Strong promoter activity of human and rat islet amyloid polypeptide/amylin gene constructs in mouse beta cells (beta TC 3)
-
De Wit L, van Mansfeld AD, van Teeffelen HA, et al. Strong promoter activity of human and rat islet amyloid polypeptide/amylin gene constructs in mouse beta cells (beta TC 3). Biochem Biophys Res Commun. 1993;192:840-848.
-
(1993)
Biochem Biophys Res Commun
, vol.192
, pp. 840-848
-
-
De Wit, L.1
Van Mansfeld, A.D.2
Van Teeffelen, H.A.3
-
230
-
-
0030065520
-
Insulin upstream factor 1 and a novel ubiquitous factor bind to the human islet amyloid polypeptide/amylin gene promoter
-
Bretherton-Watt D, Gore N, Boam DS. Insulin upstream factor 1 and a novel ubiquitous factor bind to the human islet amyloid polypeptide/amylin gene promoter. Biochem J. 1996;313:495-502.
-
(1996)
Biochem J
, vol.313
, pp. 495-502
-
-
Bretherton-Watt, D.1
Gore, N.2
Boam, D.S.3
-
231
-
-
0031007661
-
Identification of cis- and trans-active factors regulating human islet amyloid polypeptide gene expression in pancreatic beta-cells
-
Carty MD, Lillquist JS, Peshavaria M, et al. Identification of cis- and trans-active factors regulating human islet amyloid polypeptide gene expression in pancreatic beta-cells. J Biol Chem. 1997;272:11986-11993.
-
(1997)
J Biol Chem
, vol.272
, pp. 11986-11993
-
-
Carty, M.D.1
Lillquist, J.S.2
Peshavaria, M.3
-
232
-
-
0030600549
-
Involvement of the homeodomain-containing transcription factor PDX-1 in islet amyloid polypeptide gene transcription
-
Watada H, Kajimoto Y, Kaneto H, et al. Involvement of the homeodomain-containing transcription factor PDX-1 in islet amyloid polypeptide gene transcription. Biochem Biophys Res Commun. 1996;229:746-751.
-
(1996)
Biochem Biophys Res Commun
, vol.229
, pp. 746-751
-
-
Watada, H.1
Kajimoto, Y.2
Kaneto, H.3
-
233
-
-
0034685763
-
Glucose regulates islet amyloid polypeptide gene transcription in a PDX1- and calcium-dependent manner
-
Macfarlane WM, Campbell SC, Elrick LJ, et al. Glucose regulates islet amyloid polypeptide gene transcription in a PDX1- and calcium-dependent manner. J Biol Chem. 2000;275:15330-15335.
-
(2000)
J Biol Chem
, vol.275
, pp. 15330-15335
-
-
Macfarlane, W.M.1
Campbell, S.C.2
Elrick, L.J.3
-
234
-
-
0029812704
-
Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1
-
Serup P, Jensen J, Andersen FG, et al. Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1. Proc Natl Acad Sci U S A. 1996;93:9015-9020.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 9015-9020
-
-
Serup, P.1
Jensen, J.2
Andersen, F.G.3
-
235
-
-
0025996912
-
Cooperative interaction of an initiator-binding transcription initiation factor and the helix-loop-helix activator USF
-
Roy AL, Meisteremst M, Pognonec P, et al. Cooperative interaction of an initiator-binding transcription initiation factor and the helix-loop-helix activator USF. Nature. 1991;354:245-248.
-
(1991)
Nature
, vol.354
, pp. 245-248
-
-
Roy, A.L.1
Meisteremst, M.2
Pognonec, P.3
-
236
-
-
0025008564
-
IAPP/amylin gene transcriptional control region: Evidence for negative regulation
-
Mosselman S, Hoppener JW, de Wit L, et al. IAPP/amylin gene transcriptional control region: evidence for negative regulation. FEBS Lett. 1990;271:33-36.
-
(1990)
FEBS Lett
, vol.271
, pp. 33-36
-
-
Mosselman, S.1
Hoppener, J.W.2
De Wit, L.3
-
237
-
-
0029878794
-
Activation of amylin gene transcription by LIM domain homeobox gene isl-1
-
Wang M, Drucker DJ. Activation of amylin gene transcription by LIM domain homeobox gene isl-1. Mol Endocrinol. 1996;10:243-251.
-
(1996)
Mol Endocrinol
, vol.10
, pp. 243-251
-
-
Wang, M.1
Drucker, D.J.2
-
238
-
-
0026776285
-
Somatostatin gene upstream enhancer element activated by a protein complex consisting of CREB, Isl-1-like, and alpha-CBF-like transcription factors
-
Vallejo M, Penchuk L, Habener JF. Somatostatin gene upstream enhancer element activated by a protein complex consisting of CREB, Isl-1-like, and alpha-CBF-like transcription factors. J Biol Chem. 1992;267:12876-12884.
-
(1992)
J Biol Chem
, vol.267
, pp. 12876-12884
-
-
Vallejo, M.1
Penchuk, L.2
Habener, J.F.3
-
239
-
-
0026628841
-
The LIM family transcription factor Isl-1 requires cAMP response element binding protein to promote somatostatin expression in pancreatic islet cells
-
Leonard J, Serup P, Gonzalez G, et al. The LIM family transcription factor Isl-1 requires cAMP response element binding protein to promote somatostatin expression in pancreatic islet cells. Proc Natl Acad Sci U S A. 1992;89:6247-6251.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 6247-6251
-
-
Leonard, J.1
Serup, P.2
Gonzalez, G.3
-
240
-
-
0034119275
-
Reduced pancreatic polypeptide response to hypoglycemia and amylin response to arginine in subjects with a mutation in the HNF-4alpha/MODY1 gene
-
Ilag LL, Tabaei BP, Herman WH, et al. Reduced pancreatic polypeptide response to hypoglycemia and amylin response to arginine in subjects with a mutation in the HNF-4alpha/MODY1 gene. Diabetes. 2000;49:961-968.
-
(2000)
Diabetes
, vol.49
, pp. 961-968
-
-
Ilag, L.L.1
Tabaei, B.P.2
Herman, W.H.3
|