The cell physiology of biphasic insulin secretion

News in Physiological Sciences

Volumn 15, Issue 2, 2000, Pages 72-77

  Rorsman, Patrik ^a   Eliasson, Lena ^a   Renström, Erik ^a   Gromada, Jesper ^b   Barg, Sebastian ^a   Göpel, Sven ^a  

^a LUND UNIVERSITY   (Sweden)

^b NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0034410505     PISSN: 08861714     EISSN: None     Source Type: Journal    
DOI: 10.1152/physiologyonline.2000.15.2.72     Document Type: Article

References (15)

1. Ämmälä, C., L. Eliasson, K. Bokvist, O. Larsson, F. M. Ashcroft, and P. Rorsman. Exocytosis elicited by action potentials and voltage-clamp calcium currents in individual mouse pancreatic B-cells. J. Physiol. (Land.) 472: 665-688, 1993.
2. Ashcroft, F. M., and P. Rorsman. Electrophysiology of the pancreatic β-cell Prog. Biophys. Mol. Biol. 54: 87-143 1989.
3. Barbosa, R. M., A. M. Silva, A. R. Tome, J. A. Stamford, R. M. Santos, and L. M. Rosario. Control of pulsatile 5-HT/insulin secretion from single mouse pancreatic islets by intracellular calcium dynamics. J. Physiol. (Land.) 510: 135-143, 1998.
4. Cerasi, E. Aetiology of type II diabetes. In: Insulin - Molecular Biology to Pathology, edited by F. M. Ashcroft and S. J. H. Ashcroft. Oxford, UK: IRL, 1992, p. 352-392.
5. Eddlestone, G. T., S. B. Oldham, L. G. Lipson, F. H. Premdas, and P. M. Beigelman. Electrical activity, cAMP concentration, and insulin release in mouse islets of Langerhans. Am. J. Physiol. Cell Physiol. 248: C145-C153, 1985.
6. Eliasson, L., E. Renström, C. Ämmälä, P-O. Berggren, A. M. Bertorello, K. Bokvist, A. Chibalin, J. T. Deeney, P. R. Flatt, J. Gäbel, J. Gromada, O. Larsson, P. Lindström, C. J. Rhodes, and P. Rorsman. PKC-dependent stimulation of exocytosis by sulfonylureas in pancreatic β cells. Science 271: 813-815, 1996.
7. 2+-induced exocytosis in mouse pancreatic B-cells. J. Physiol. (Lond.) 503: 399-412, 1997.
8. Inagaki, N., T. Gonoi, J. P. Clement IV, N. Namba, J. Inazawa, G. Gonzalez, L. Aguilar-Bryan, S. Seino, and J. Bryan. Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor. Science 270: 1166-1170, 1995.
9. Khan, A., V. Chandramouli, C. G. Östenson, H. Löw, B. R. Landau, and S. Efendic. Glucose cycling in islets from healthy and diabetic rats. Diabetes 39: 456-459, 1990.
10. Ma, Y. H., J. Wang, G. G. Rodd, J. L. Bolaffi, and G. M. Grodsky. Differences in insulin secretion between the rat and mouse: role of cAMP. Eur. J. Endocrinol. 132: 370-376, 1995.
11. Parsons, T. D., J. R. Coorssen, H. Horstmann, and W. Almers. Docked granules, the exocytic burst, and the need for ATP hydrolysis in endocrine cells. Neuron 15: 1085-1096, 1995.
12. Renström, E., L. Eliasson, and P. Rorsman. Protein kinase A-dependent and -independent stimulation of exocytosis by cAMP in mouse pancreatic B-cells. J. Physiol. (Lond.) 502: 105-118, 1997.
13. Steyer, J. A., H. Horstmann, and W. Almers. Transport, docking and exocytosis of single secretory granules in live chromaffin cells. Nature 388: 474-478, 1997.
14. + channels is impaired in β-cells of the GK rat. A new genetic model of NIDDM. Diabetes 42: 1446-1453, 1993.
15. 2+ and G-proteins. Diabetes Rev. 4: 276-297, 1996.