Glucose- and GTP-dependent stimulation of the carboxyl methylation of CDC42 in rodent and human pancreatic islets and pure β cells. Evidence for an essential role of GTP-binding proteins in nutrient-induced insulin secretion

Journal of Clinical Investigation

Volumn 98, Issue 2, 1996, Pages 540-555

  Kowluru, Anjaneyulu ^a,b,e   Seavey, Scott E ^a,b   Li, Guodong ^a,b   Sorenson, Robert L ^c   Weinhaus, Anthony J ^c   Nesher, Rafael ^d   Rabaglia, Mary E ^a,b   Vadakekalam, Jacob ^a,b   Metz, Stewart A ^a,b  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b WILLIAM S MIDDLETON MEMORIAL VETERANS HOSPITAL   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^d HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^e University of Wisconsin Health   (United States)

Author keywords

carboxyl methylation; CDC42; GTP binding proteins; insulin secretion; pancreatic cell

Indexed keywords

CARBOXYL GROUP; GLUCOSE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE; GUANOSINE TRIPHOSPHATE; INSULIN; MYCOPHENOLIC ACID; PHOSPHATIDYLINOSITIDE; S ADENOSYLHOMOCYSTEINE;

ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; INSULIN RELEASE; MALE; METHYLATION; MICROSCOPY; NONHUMAN; NUTRIENT; PANCREAS ISLET; PANCREAS ISLET BETA CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT;

EID: 0030056516     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118822     Document Type: Article

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