-
1
-
-
0026471057
-
Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: Building a functional insulin minienhancer complex
-
German MS, Wang J, Chadwick RB, Rutter WJ 1992 Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: building a functional insulin minienhancer complex. Genes Dev 6:2165-2176
-
(1992)
Genes Dev
, vol.6
, pp. 2165-2176
-
-
German, M.S.1
Wang, J.2
Chadwick, R.B.3
Rutter, W.J.4
-
2
-
-
0026016780
-
Two related helix-loop-helix proteins participate in separate cell-specific complexes that bind the insulin enhancer
-
German MS, Blanar MA, Nelson C, Moss LG, Rutter WJ 1991 Two related helix-loop-helix proteins participate in separate cell-specific complexes that bind the insulin enhancer. Mol Endocrinol 5:292-299
-
(1991)
Mol Endocrinol
, vol.5
, pp. 292-299
-
-
German, M.S.1
Blanar, M.A.2
Nelson, C.3
Moss, L.G.4
Rutter, W.J.5
-
3
-
-
0025971911
-
Pancreatic beta-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteins
-
Cordle SR, Henderson E, Masuoka H, Weil PA, Stein R 1991 Pancreatic beta-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteins. Mol Cell Biol 11:1734-1738
-
(1991)
Mol Cell Biol
, vol.11
, pp. 1734-1738
-
-
Cordle, S.R.1
Henderson, E.2
Masuoka, H.3
Weil, P.A.4
Stein, R.5
-
4
-
-
0027960493
-
Two distinct class A helix-loop-helix transcription factors, E2A and BETA1, form separate DNA binding complexes on the insulin gene E box
-
Peyton M, Moss LG, Tsai M-J 1994 Two distinct class A helix-loop-helix transcription factors, E2A and BETA1, form separate DNA binding complexes on the insulin gene E box. J Biol Chem 269:25936-25941
-
(1994)
J Biol Chem
, vol.269
, pp. 25936-25941
-
-
Peyton, M.1
Moss, L.G.2
Tsai, M.-J.3
-
5
-
-
0026742624
-
Hepatocyte nuclear factor 1α is expressed in a hamster insulinoma line and transactivates the rat insulin I gene
-
Emens LA, Landers DW, Moss LG 1992 Hepatocyte nuclear factor 1α is expressed in a hamster insulinoma line and transactivates the rat insulin I gene. Proc Natl Acad Sci USA 89:7300-7304
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7300-7304
-
-
Emens, L.A.1
Landers, D.W.2
Moss, L.G.3
-
6
-
-
0026386775
-
Novel insulin promoter- and enhancer-binding proteins that discriminate between pancreatic alpha and β-cells
-
Ohlsson H, Thor S, Edlund T 1991 Novel insulin promoter- and enhancer-binding proteins that discriminate between pancreatic alpha and β-cells. Mol Endocrinol 5:897-904
-
(1991)
Mol Endocrinol
, vol.5
, pp. 897-904
-
-
Ohlsson, H.1
Thor, S.2
Edlund, T.3
-
7
-
-
0025217027
-
Islet amyloid polypeptide
-
Nishi M, Sanke T, Nagamatsu S, Bell GI, Steiner DF 1990 Islet amyloid polypeptide. J Biol Chem 265:4173-4176
-
(1990)
J Biol Chem
, vol.265
, pp. 4173-4176
-
-
Nishi, M.1
Sanke, T.2
Nagamatsu, S.3
Bell, G.I.4
Steiner, D.F.5
-
8
-
-
0028354142
-
Amylin compared with calcitonin gene-related peptide:Structure, biology and relevance to metabolic disease
-
Cooper GJS 1994 Amylin compared with calcitonin gene-related peptide:Structure, biology and relevance to metabolic disease. Endocr Rev 15:163-201
-
(1994)
Endocr Rev
, vol.15
, pp. 163-201
-
-
Cooper, G.J.S.1
-
9
-
-
0026602931
-
The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical β-cell nuclear complexes
-
German MS, Moss LG, Wang J, Rutter WJ 1992 The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical β-cell nuclear complexes. Mol Cell Biol 12:1777-1788
-
(1992)
Mol Cell Biol
, vol.12
, pp. 1777-1788
-
-
German, M.S.1
Moss, L.G.2
Wang, J.3
Rutter, W.J.4
-
10
-
-
0028136103
-
Expression of the trans-active factors that stimulate insulin control element-mediated activity appear to precede insulin gene transcription
-
Robinson GLW G, Peshavaria M, Henderson E, Shieh S-Y, Tsai M-J, Teitelman G, Stein R 1994 Expression of the trans-active factors that stimulate insulin control element-mediated activity appear to precede insulin gene transcription. J Biol Chem 269:2452-2460
-
(1994)
J Biol Chem
, vol.269
, pp. 2452-2460
-
-
Robinson, G.L.W.G.1
Peshavaria, M.2
Henderson, E.3
Shieh, S.-Y.4
Tsai, M.-J.5
Teitelman, G.6
Stein, R.7
-
11
-
-
0028314969
-
IDX-1:A new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene
-
Miller CP, McGehee Jr RE, Habener JF 1994 IDX-1:a new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene. EMBO J 13:1145-1156
-
(1994)
EMBO J
, vol.13
, pp. 1145-1156
-
-
Miller, C.P.1
McGehee Jr., R.E.2
Habener, J.F.3
-
12
-
-
0027384997
-
IPF1, a homeodomain-containing transactivator of the insulin gene
-
Ohlsson H, Karlsson K, Edlund T 1993 IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO J 12:4251-4259
-
(1993)
EMBO J
, vol.12
, pp. 4251-4259
-
-
Ohlsson, H.1
Karlsson, K.2
Edlund, T.3
-
13
-
-
0027373441
-
Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin gene expression in pancreatic islet cells
-
Leonard J, Peers B, Johnson T, Ferrei K, Lee S, Montminy MR 1993 Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin gene expression in pancreatic islet cells. Mol Endocrinol 7:1275-1283
-
(1993)
Mol Endocrinol
, vol.7
, pp. 1275-1283
-
-
Leonard, J.1
Peers, B.2
Johnson, T.3
Ferrei, K.4
Lee, S.5
Montminy, M.R.6
-
14
-
-
0028567837
-
Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1
-
Peers B, Leonard J, Sharma S, Teitelman G, Montminy MR 1994 Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1. Mol Endocrinol 8:1798-1806
-
(1994)
Mol Endocrinol
, vol.8
, pp. 1798-1806
-
-
Peers, B.1
Leonard, J.2
Sharma, S.3
Teitelman, G.4
Montminy, M.R.5
-
15
-
-
0029047865
-
The LIM domain homeobox gene isl-1 is a positive regulator of islet cell-specific proglucagon gene transcription
-
Wang M, Drucker DJ 1995 The LIM domain homeobox gene isl-1 is a positive regulator of islet cell-specific proglucagon gene transcription. J Biol Chem 270:12646-12652
-
(1995)
J Biol Chem
, vol.270
, pp. 12646-12652
-
-
Wang, M.1
Drucker, D.J.2
-
16
-
-
0027987138
-
Pancreatic beta cells express a diverse set of homeobox genes
-
Rudnick A, Ling TY, Odagiri H, Rutter WJ, German MS 1994 Pancreatic beta cells express a diverse set of homeobox genes. Proc Natl Acad Sci USA 91:12203-12207
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 12203-12207
-
-
Rudnick, A.1
Ling, T.Y.2
Odagiri, H.3
Rutter, W.J.4
German, M.S.5
-
17
-
-
0028149890
-
Insulin-promoter-factor 1 is required for pancreas development in mice
-
Jonsson J, Carlsson L, Edlund T, Edlund H 1994 Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 371:606-609
-
(1994)
Nature
, vol.371
, pp. 606-609
-
-
Jonsson, J.1
Carlsson, L.2
Edlund, T.3
Edlund, H.4
-
18
-
-
0025280050
-
Insulin gene enhancer binding protein isl-1 is a member of a novel class of proteins containing both a homeo-and a Cys-His domain
-
Karlsson O, Thor S, Norberg T, Ohlsson H, Edlund T 1990 Insulin gene enhancer binding protein isl-1 is a member of a novel class of proteins containing both a homeo-and a Cys-His domain. Nature 344:879-882
-
(1990)
Nature
, vol.344
, pp. 879-882
-
-
Karlsson, O.1
Thor, S.2
Norberg, T.3
Ohlsson, H.4
Edlund, T.5
-
19
-
-
0026335927
-
The homeodomain LIM protein isl-1 is expressed in subsets of neurons and endocrine cells in the adult rat
-
Thor S, Ericson J, Brännström T, Edlund T 1991 The homeodomain LIM protein isl-1 is expressed in subsets of neurons and endocrine cells in the adult rat. Neuron 7:881-889
-
(1991)
Neuron
, vol.7
, pp. 881-889
-
-
Thor, S.1
Ericson, J.2
Brännström, T.3
Edlund, T.4
-
20
-
-
0025794399
-
Islet cell and extrapancreatic expression of the LIM domain homeobox gene isl-1
-
Dong J, Asa SL, Drucker DJ 1991 Islet cell and extrapancreatic expression of the LIM domain homeobox gene isl-1. Mol Endocrinol 5:1633-1641
-
(1991)
Mol Endocrinol
, vol.5
, pp. 1633-1641
-
-
Dong, J.1
Asa, S.L.2
Drucker, D.J.3
-
21
-
-
0024326627
-
Human islet amyloid polypeptide gene: Complete nucleotide sequence, chromosomal localization, and evolutionary history
-
Nishi M, Sanke T, Seino S, Eddy RL, Fan Y-S, Byers MG, Shows TB, Bell GI, Steiner DF 1989 Human islet amyloid polypeptide gene: complete nucleotide sequence, chromosomal localization, and evolutionary history. Mol Endocrinol 3:1775-1781
-
(1989)
Mol Endocrinol
, vol.3
, pp. 1775-1781
-
-
Nishi, M.1
Sanke, T.2
Seino, S.3
Eddy, R.L.4
Fan, Y.-S.5
Byers, M.G.6
Shows, T.B.7
Bell, G.I.8
Steiner, D.F.9
-
22
-
-
0027439276
-
The cysteine-rich LIM domains inhibit DNA binding by the associated homeodomain in Isl-1
-
Sánchez-García I, Osada H, Forster A, Rabbitts TH 1993 The cysteine-rich LIM domains inhibit DNA binding by the associated homeodomain in Isl-1. EMBO J 12:4243-4250
-
(1993)
EMBO J
, vol.12
, pp. 4243-4250
-
-
Sánchez-García, I.1
Osada, H.2
Forster, A.3
Rabbitts, T.H.4
-
23
-
-
0023723641
-
Alpha-cell-specific expression of the glucagon gene is conferred to the glucagon promoter element by the interactions of DNA-binding proteins
-
Philippe J, Drucker DJ, Knepel W, Jepeal L, Misulovin Z, Habener JF 1988 Alpha-cell-specific expression of the glucagon gene is conferred to the glucagon promoter element by the interactions of DNA-binding proteins. Mol Cell Biol 8:4877-4888
-
(1988)
Mol Cell Biol
, vol.8
, pp. 4877-4888
-
-
Philippe, J.1
Drucker, D.J.2
Knepel, W.3
Jepeal, L.4
Misulovin, Z.5
Habener, J.F.6
-
24
-
-
0028351026
-
The LIM domain homeobox gene isl-1 Conservation of human, hamster, and rat complementary deoxyribonucleic acid sequences and expression in cell types of nonneuroendocrine lineage
-
Wang M, Drucker DJ 1994 The LIM domain homeobox gene isl-1 Conservation of human, hamster, and rat complementary deoxyribonucleic acid sequences and expression in cell types of nonneuroendocrine lineage. Endocrinology 134:1416-1422
-
(1994)
Endocrinology
, vol.134
, pp. 1416-1422
-
-
Wang, M.1
Drucker, D.J.2
-
25
-
-
0026628841
-
The LIM family transcription factor Isl-1 requires cAMP response element binding protein to promote somatostatin expression in pancreatic islet cells
-
Leonard J, Serup P, Gonzalez G, Edlund T, Montminy M 1992 The LIM family transcription factor Isl-1 requires cAMP response element binding protein to promote somatostatin expression in pancreatic islet cells. Proc Natl Acad Sci USA 89:6247-6251
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 6247-6251
-
-
Leonard, J.1
Serup, P.2
Gonzalez, G.3
Edlund, T.4
Montminy, M.5
-
26
-
-
0022979576
-
CAT vectors for analysis of eukaryotic promoters and enhancers
-
Prost E, Moore DD 1986 CAT vectors for analysis of eukaryotic promoters and enhancers. Gene 45:107-111
-
(1986)
Gene
, vol.45
, pp. 107-111
-
-
Prost, E.1
Moore, D.D.2
-
27
-
-
0027248698
-
Strong promoter activity of human and rat islet amyloid polypeptide/amylin gene constructs in mouse beta cells (βTC3)
-
De Wit L, van Mansfield ADM, van Teeffelen HAA M, Lips CJM, Hoppener JWM 1993 Strong promoter activity of human and rat islet amyloid polypeptide/amylin gene constructs in mouse beta cells (βTC3). Biochem Biophys Res Commun 192:840-848
-
(1993)
Biochem Biophys Res Commun
, vol.192
, pp. 840-848
-
-
De Wit, L.1
Van Mansfield, A.D.M.2
Van Teeffelen, H.A.A.M.3
Lips, C.J.M.4
Hoppener, J.W.M.5
-
28
-
-
0025890979
-
Islet amyloid polypeptide and insulin expression are controlled differently in primary and transformed islet cell lines
-
Madsen OD, Nielsen JH, Michelsen B, Westermark P, Betsholtz C, Nishi M, Steiner DF 1991 Islet amyloid polypeptide and insulin expression are controlled differently in primary and transformed islet cell lines. Mol Endocrinol 5:143-148
-
(1991)
Mol Endocrinol
, vol.5
, pp. 143-148
-
-
Madsen, O.D.1
Nielsen, J.H.2
Michelsen, B.3
Westermark, P.4
Betsholtz, C.5
Nishi, M.6
Steiner, D.F.7
-
29
-
-
0027973545
-
Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia
-
Wadman I, Li J, Bash RO, Forster A, Osada H, Rabbitts TH, Baer R 1994 Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia. EMBO J 13:4831-4839
-
(1994)
EMBO J
, vol.13
, pp. 4831-4839
-
-
Wadman, I.1
Li, J.2
Bash, R.O.3
Forster, A.4
Osada, H.5
Rabbitts, T.H.6
Baer, R.7
-
30
-
-
0027892020
-
Cooperative interactions between the Caenorhabditis elegans homeoproteins unc-86 and mec-3
-
Xue D, Tu Y, Chalfie M 1993 Cooperative interactions between the Caenorhabditis elegans homeoproteins unc-86 and mec-3. Science 261:1324-1328
-
(1993)
Science
, vol.261
, pp. 1324-1328
-
-
Xue, D.1
Tu, Y.2
Chalfie, M.3
-
31
-
-
0028000042
-
The LIM/double zinc-finger motif functions as a protein dimerization domain
-
Feuerstein R, Wang X, Song D, Cooke NE, Liebhaber SA 1994 The LIM/double zinc-finger motif functions as a protein dimerization domain. Proc Natl Acad Sci USA 91:10655-10659
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 10655-10659
-
-
Feuerstein, R.1
Wang, X.2
Song, D.3
Cooke, N.E.4
Liebhaber, S.A.5
-
32
-
-
0028587878
-
Role of the LIM class homeodomain protein Xlim-1 in neural and muscle induction by the Spemann organizer in Xenopus
-
Taira M, Otani H, Saint-Jeannet J-P, Dawid IB 1994 Role of the LIM class homeodomain protein Xlim-1 in neural and muscle induction by the Spemann organizer in Xenopus. Nature 372:677-679
-
(1994)
Nature
, vol.372
, pp. 677-679
-
-
Taira, M.1
Otani, H.2
Saint-Jeannet, J.-P.3
Dawid, I.B.4
-
33
-
-
0023479159
-
Electrophoretic assay for DNA-binding proteins
-
Varshavsky A 1987 Electrophoretic assay for DNA-binding proteins. Methods Enzymol 151:551-565
-
(1987)
Methods Enzymol
, vol.151
, pp. 551-565
-
-
Varshavsky, A.1
-
34
-
-
0024380087
-
Rapid detection of octamer binding proteins with 'mini-extracts' prepared from a small number of cells
-
Schreiber E, Matthias P, Muller MM, Schaffner W 1989 Rapid detection of octamer binding proteins with 'mini-extracts' prepared from a small number of cells. Nucleic Acids Res 17:6419
-
(1989)
Nucleic Acids Res
, vol.17
, pp. 6419
-
-
Schreiber, E.1
Matthias, P.2
Muller, M.M.3
Schaffner, W.4
-
35
-
-
0023230550
-
Glucagon gene 5′-flanking sequences promote islet cell-specific glucagon gene transcription
-
Drucker DJ, Philippe J, Jepeal L, Habener JF 1987 Glucagon gene 5′-flanking sequences promote islet cell-specific glucagon gene transcription. J Biol Chem 262: 15659-15665
-
(1987)
J Biol Chem
, vol.262
, pp. 15659-15665
-
-
Drucker, D.J.1
Philippe, J.2
Jepeal, L.3
Habener, J.F.4
-
36
-
-
0025010183
-
Islet amyloid polypeptide: Structure and upstream sequences of the IAPP gene in rat and man
-
van Mansfield ADM, Mosselman S, Hoppener JWM, Zandberg J, van Teeffelen HAA M, Baas PD, Lips CJM, Jansz HS 1990 Islet amyloid polypeptide: structure and upstream sequences of the IAPP gene in rat and man. Biochim Biophys Acta 1087:235-240
-
(1990)
Biochim Biophys Acta
, vol.1087
, pp. 235-240
-
-
Van Mansfield, A.D.M.1
Mosselman, S.2
Hoppener, J.W.M.3
Zandberg, J.4
Van Teeffelen, H.A.A.M.5
Baas, P.D.6
Lips, C.J.M.7
Jansz, H.S.8
-
37
-
-
0029095180
-
The proglucagon gene upstream enhancer contains positive and negative domains important for tissue-specific proglucagon gene transcription
-
Jin T, Drucker DJ 1995 The proglucagon gene upstream enhancer contains positive and negative domains important for tissue-specific proglucagon gene transcription. Mol Endocrinol 9:1306-1320
-
(1995)
Mol Endocrinol
, vol.9
, pp. 1306-1320
-
-
Jin, T.1
Drucker, D.J.2
|