Modeling the Adenosine Receptors: Comparison of the Binding Domains of A2A Agonists and Antagonists

Journal of Medicinal Chemistry

Volumn 46, Issue 23, 2003, Pages 4847-4859

  Kim, Soo Kyung ^a   Gao, Zhan Guo ^a   Van Rompaey, Philippe ^b   Gross, Ariel S ^a   Chen, Aishe ^a   Van Calenbergh, Serge ^b   Jacobson, Kenneth A ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b Lab voor Medicinale Chemie (FFW)   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

9 CHLORO 2 (2 FURYL) 5,6 DIHYDRO 5 IMINO 1,2,4 TRIAZOLO[2,3 C]QUINAZOLINE; ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR AGONIST; ADENOSINE A2A RECEPTOR ANTAGONIST; AMIDE; AMINO ACID; ASPARAGINE; ASPARTIC ACID; GLUTAMINE; HISTIDINE; METHYL GROUP; PURINE DERIVATIVE; RHODOPSIN; RIBOSE; SERINE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; AUTOMATION; BINDING SITE; COMPLEX FORMATION; DRUG CONFORMATION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HYDROGEN BOND; HYDROPHILICITY; HYDROPHOBICITY; LIGAND BINDING; NONHUMAN; PROTEIN CONFORMATION; PROTEIN DOMAIN; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS; VALIDATION PROCESS;

EID: 0242362595     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0300431     Document Type: Article

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