Serine and alanine mutagenesis of the nine native cysteine residues of the human A1 adenosine receptor

Biochemical Pharmacology

Volumn 60, Issue 11, 2000, Pages 1647-1654

  Scholl, D Jason ^a   Wells, Jack N ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adenosine; Adenosine agonist; Adenosine antagonist; Cysteine mutagenesis; Disulfide bond; G protein coupled receptor

Indexed keywords

8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A1 RECEPTOR; ALANINE; CYSTEINE; PHENYLISOPROPYLADENOSINE; SERINE; THEOPHYLLINE;

ANIMAL CELL; ARTICLE; DISSOCIATION CONSTANT; DRUG RECEPTOR BINDING; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

ALANINE; AMINO ACID SEQUENCE; CELLS, CULTURED; CYSTEINE; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PROTEIN CONFORMATION; RADIOLIGAND ASSAY; RECEPTORS, PURINERGIC P1; SERINE; TRANSFECTION; TRITIUM; XANTHINES;

EID: 0034578519     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(00)00474-3     Document Type: Article

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