Site-directed mutagenesis of the human adenosine A(2A) receptor. Critical involvement of Glu13 in agonist recognition

European Journal of Pharmacology

Volumn 310, Issue 2-3, 1996, Pages 269-272

  IJzerman, Ad P ^a   Von Frijtag Drabbe Künzel, Jacobien K ^a   Kim, Jeongho ^b   Jiang, Qiaoling ^b   Jacobson, Kenneth A ^b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Adenosine A(2A) receptor, human; Amiloride; CGS21680; Glutamic acid; Mutation; XAC

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 8 [4 (2 AMINOETHYLCARBAMOYL)METHOXYPHENYL] 1,3 DIPROPYLXANTHINE; 9 CHLORO 2 (2 FURYL) 5,6 DIHYDRO 5 IMINO 1,2,4 TRIAZOLO[2,3 C]QUINAZOLINE; ADENOSINE A2 RECEPTOR; AMILORIDE; GLUTAMIC ACID; GLUTAMINE; RADIOLIGAND;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; HUMAN; HUMAN TISSUE; LIGAND BINDING; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR AFFINITY; SITE DIRECTED MUTAGENESIS;

EID: 0030605986     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(96)00495-5     Document Type: Article

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