Identification of the adenine binding site of the human A1 adenosine receptor

Journal of Biological Chemistry

Volumn 274, Issue 6, 1999, Pages 3617-3621

  Rivkees, Scott A ^a   Barbhaiya, Hemang ^a   IJzerman, Adrian P ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

2 CHLORO 6 N CYCLOPENTYLADENOSINE; 2 CHLOROADENOSINE; 6 N CYCLOPENTYLADENOSINE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; ADENOSINE A3 RECEPTOR; ADENOSINE RECEPTOR; ADENOSINE RECEPTOR STIMULATING AGENT; PHENYLISOPROPYLADENOSINE; TRITIUM;

ARTICLE; BINDING AFFINITY; BINDING SITE; COMPUTER MODEL; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR MODEL; PRIORITY JOURNAL; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS;

ADENINE; AMIDES; AMINO ACID SEQUENCE; AMINO ACIDS; BINDING SITES; DNA, COMPLEMENTARY; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, PURINERGIC P1;

TRITIUM;

EID: 0033524916     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.6.3617     Document Type: Article

References (25)

1. Shryock, J. C., and Belardinelli, L. (1997) Am. J. Cardiol. 79, 2-10
2. Brundege, J. M., and Dunwiddie, T. V. (1997) Adv. Pharmacol. 39, 353-391
3. Palmer, T. M., and Stiles, G. L. (1995) Neuropharmacology 34, 683-694
4. Olah, M. E., Ren, H., Ostrowski, J., Jacobson, K. A., and Stiles, G. L. (1992) J. Biol. Chem. 267, 10764-10770
5. Tucker, A. L., Robeva, A. S., Taylor, H. E., Holeton, D., Bockner, M., Lynch, K. R., and Linden, J. (1994) J. Biol. Chem. 269, 27900-27906
6. Townsend-Nicholson, A., and Schofield, P. R. (1994) J. Biol. Chem. 269, 2373-2376
7. Rivkees, S. A., Lasbury, M. E., and Barbhaiya, H. (1995) J. Biol. Chem. 270, 20485-20490
8. Tivedi, B. K., Bridges, A. J., and Bruns, R. F. (1990) in Adenosine and Adenosine Receptors (Williams, M., ed) pp. 57-103, Humana Press, Clifton, NJ
9. Rivkees, S. A., Lasbury, M. E., Stiles, G. L., Henergariu, O., and Vance, G. (1995) Endocrine 3, 623-629
10. Ho, S. N., Hunt, H. D., Horton, R. M., Pullen, J. K., and Pease, L. R. (1989) Gene (Amst.) 77, 51-59
11. Barbhaiya, H., McClain, R., Ijzerman, A., and Rivkees, S. A. (1996) Mol. Pharmacol. 50, 1635-1642
12. Cullen, B. R. (1987) Methods Enzymol. 152, 684-704
13. Jiang, Q., van Rhee, A. M., Kim, J., Yehle, S., Wess, J., and Jacobson, K. A. (1996) Mol. Pharmacol. 50, 512-521
14. IJzerman, A. P., van Galen, P. J., and Jacobson, K. A. (1992) Drug Des. Discov. 9, 49-67
15. McPherson, G. A. (1985) J. Pharmacol. Methods 14, 213-228
16. Unger, V. M., Hargrave, P. A., Baldwin, J. M., and Schertler, G. F. (1997) Nature 389, 203-206
17. IJzerman, A. P., von Frijtag Drabbe Kunzel, J. K., Kim, J., Jiang, Q., and Jacobson, K. A. (1996) Eur. J. Pharmacol. 310, 269-272
18. Baldwin, J. M. (1993) EMBO J. 12, 1693-1703
19. Baldwin, J. M. (1994) Curr. Opin. Cell Biol. 6, 180-190
20. IJzerman, A. P., van der Wenden, E. M., van Galen, P. J., and Jacobson, K. A. (1994) Eur. J. Pharmacol. 268, 95-104
21. van Galen, P. J., van Bergen, A. H., Gallo-Rodriguez, C., Melman, N., Olah, M. E., IJzerman, A. P., Stiles, G. L., and Jacobson, K. A. (1994) Mol. Pharmacol. 45, 1101-1111
22. Kennedy, A. P., Mangum, K. C., Linden, J., and Wells, J. N. (1996) Mol. Pharmacol. 50, 789-798
23. Ukena, D., Padgett, W. L., Hong, O., Daly, J. W., Daly, D. T., and Olsson, R. A. (1987) FEBS Lett. 215, 203-208
24. Shryock, J. C., Travagli, H. C., and Belardinelli, L. (1992) J. Pharmacol. Exp. Ther. 260, 1292-1299
25. Olah, M. E., Jacobson, K. A., and Stiles, G. L. (1994) J. Biol. Chem. 269, 24692-24698