A homology-based model o fthe human 5-HT2A receptor derived from an in silico activated G-protein coupled receptor

Journal of Computer-Aided Molecular Design

Volumn 16, Issue 7, 2002, Pages 511-520

  Chambers, James J ^a   Nichols, David E ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

5 HT2A receptor; G protein coupled receptor; Ligand binding; Molecular dynamics; Receptor activation

Indexed keywords

BINDING ENERGY; CHEMICAL ACTIVATION; CHROMOPHORES; CRYSTAL STRUCTURE; LIGANDS; PROTEINS;

5-HT2A RECEPTOR; BOVINE RHODOPSIN; CONSTRAINED MOLECULAR DYNAMICS; CRYSTALS STRUCTURES; G PROTEIN COUPLED RECEPTORS; HOMOLOGY-BASED MODELING; IN-SILICO; ISOMERISATION; LIGAND BINDING; RECEPTOR ACTIVATION;

MOLECULAR DYNAMICS;

11 CIS RETINAL; AMPHETAMINE DERIVATIVE; ERGOLINE DERIVATIVE; G PROTEIN COUPLED RECEPTOR; LIGAND; RHODOPSIN; SEROTONIN 2A RECEPTOR; TRYPTAMINE DERIVATIVE;

ARTICLE; CHROMATOPHORE; COMPUTER MODEL; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENERGY YIELD; HUMAN; ISOMERISM; LIGAND BINDING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN STRUCTURE; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS; STRUCTURAL HOMOLOGY;

EID: 0036663630     PISSN: 0920654X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1021275430021     Document Type: Article

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