Thirty years of polyamine-related approaches to cancer therapy. Retrospect and prospect. Part 2. Structural analogues and derivatives

Current Drug Targets

Volumn 4, Issue 7, 2003, Pages 565-585

  Seiler, Nikolaus ^a  

^a IRCAD   (France)

Author keywords

Cancer; Polyamine transport; Polyamines; Putrescine; Spermidine; Spermine; Structural analogues; Therapy

Indexed keywords

1,3 PROPANEDIAMINE; 1,7 DIAMINOHEPTANE; ANTINEOPLASTIC AGENT; CALMODULIN INHIBITOR; CHLORAMBUCIL; EFLORNITHINE; N,N' BIS(2,3 BUTADIENYL)PUTRESCINE; N,N' BIS(ETHYLAMINOPROPYL)1,7 HEPTANEDIAMINE; N1,N11 [(CYCLOHEPTYL)METHYL]NORSPERMINE; N1,N11 [(CYCLOPROPYL)METHYL]NORSPERMINE; N1,N11 DIETHYLNORSPERMINE; N1,N12 DIETHYLSPERMINE; N1,N14 DIETHYLHOMOSPERMINE; ORI 1202; POLYAMINE; POLYAMINE DERIVATIVE; PUTRESCINE; PUTRESCINE DERIVATIVE; SPERMIDINE; SPERMIDINE DERIVATIVE; SPERMINE; SPERMINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; CANCER INHIBITION; CATABOLISM; CELL GROWTH; CELL LEVEL; CELL PROLIFERATION; CELL TRANSPORT; CYTOTOXICITY; DRUG EFFICACY; DRUG SYNTHESIS; DRUG TARGETING; ENZYME INHIBITION; GROWTH INHIBITION; HUMAN; MOLECULAR MIMICRY; NONHUMAN; POLYAMINE SYNTHESIS; REVIEW; STRUCTURE ACTIVITY RELATION; TUMOR CELL;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOGENIC POLYAMINES; CLINICAL TRIALS; HUMANS; NEOPLASMS; POLYAMINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0141761500     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389450033490876     Document Type: Review

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