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Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 2, 2001, Pages 251-254

Polyamines with N-(3-phenylpropyl) substituents are effective competitive inhibitors of trypanothione reductase and trypanocidal agents

(8) Li, Zhili a Fennie, Michael W b Ganem, Bruce c Hancock, Matthew T a Kobašlija, Muris b Rattendi, Donna d Bacchi, Cyrus J d O'Sullivan, Mary C b

a INDIANA STATE UNIVERSITY (United States)

b CANISIUS COLLEGE (United States)

c Department of Obstetrics Gynecology (United States)

d PACE UNIVERSITY (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITRYPANOSOMAL AGENT; POLYAMINE; SPERMIDINE; SPERMINE DERIVATIVE; TRYPANOTHIONE REDUCTASE;

ARTICLE; COMPETITIVE INHIBITION; ENZYME INHIBITION; IC 50; NONHUMAN; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI;

ANIMALS; BINDING, COMPETITIVE; COMBINATORIAL CHEMISTRY TECHNIQUES; ENZYME INHIBITORS; INHIBITORY CONCENTRATION 50; KINETICS; NADH, NADPH OXIDOREDUCTASES; POLYAMINES; SPERMIDINE; SPERMINE; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMA CRUZI;

TRYPANOSOMA; TRYPANOSOMA CRUZI;

EID: 0035931356 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/S0960-894X(00)00643-0 Document Type: Article

Times cited : (60)

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