Synthesis and evaluation of hydroxylated polyamine analogues as antiproliferatives

Journal of Medicinal Chemistry

Volumn 44, Issue 15, 2001, Pages 2451-2459

  Bergeron, R J ^a   Muller R ^a   Huang, G ^a   McManis, J S ^a   Algee, S E ^a   Yao, H ^a   Weimar, W R ^a   Wiegand, J ^a  

^a UNIVERSITY OF FLORIDA HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; ADENOSYLMETHIONINE DECARBOXYLASE; ANTINEOPLASTIC AGENT; N1 CYCLOPROPYLMETHYL 2,10 DIHYDROXY N11 ETHYLNORSPERMINE; N1 CYCLOPROPYLMETHYL N11 ETHYLNORSPERMINE; ORNITHINE DECARBOXYLASE; POLYAMINE DERIVATIVE; PUTRESCINE; SPERMIDINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG HYDROXYLATION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; MOUSE; MURINE LEUKEMIA; NEUROTOXICITY; NONHUMAN;

ACETYLTRANSFERASES; ACUTE TOXICITY TESTS; ADENOSYLMETHIONINE DECARBOXYLASE; ANIMALS; ANTINEOPLASTIC AGENTS; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; INHIBITORY CONCENTRATION 50; LEUKEMIA L1210; MICE; ORNITHINE DECARBOXYLASE; SPERMINE; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0035913054     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm000532q     Document Type: Article

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