N-benzylpolyamines as vectors of boron and fluorine for cancer therapy and imaging: Synthesis and biological evaluation

Journal of Medicinal Chemistry

Volumn 44, Issue 22, 2001, Pages 3653-3664

  Martin, B ^a   Posseme F ^b   Le Barbier, C ^b   Carreaux, F ^b   Carboni, B ^b   Seiler, N ^a   Moulinoux, J P ^a   Delcros, J G ^a  

^a Groupe de Recherche en The rapeutique AntiCance reuse   (France)

^b Chimie et Photonique Moleculaires Rennes   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BOROCAPTATE; BORON 10; DNA; EFLORNITHINE; FLUORINE 18; N (4 AMINOBUTYL)[[4 (DIHYDROXYBORYL)PHENYL]METHYL]AMINE; N [3 [(4 AMINOBUTYL)AMINO]PROPYL][(4 FLUOROPHENYL)METHYL]AMINE; N [3 [(4 AMINOBUTYL)AMINO]PROPYL][[4 (DIHYDROXYBORYL)PHENYL]METHYL]AMINE; PHENYLALANINE DERIVATIVE; POLYAMINE; PUTRESCINE DERIVATIVE; SPERMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER CELL; CHO CELL; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; DRUG SYNTHESIS; DRUG TRANSPORT; GROWTH INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; METABOLISM; MOUSE; NONHUMAN; RAT;

ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; BORON COMPOUNDS; BORON NEUTRON CAPTURE THERAPY; CELL LINE; DNA; PUTRESCINE; SPERMIDINE; SPERMINE; STRUCTURE-ACTIVITY RELATIONSHIP; TOMOGRAPHY, EMISSION-COMPUTED; TUMOR CELLS, CULTURED;

EID: 0035950083     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010897q     Document Type: Article

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