2,2'-dithiobis(N-ethyl-spermine-5-carboxamide) is a high affinity, membrane-impermeant antagonist of the mammalian polyamine transport system

Journal of Biological Chemistry

Volumn 271, Issue 44, 1996, Pages 27556-27563

  Hubert, Maria ^a   Pelletier, Joële G ^a   Torossian, Krikor ^a   Dionne, Patricia ^a   Gamache, Isabelle ^a   Charest Gaudreault, René ^b   Audette, Marie ^a   Poulin, Richard ^a,b  

^a UNIVERSITÉ LAVAL   (Canada)

^b LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEAMINE DERIVATIVE; POLYAMINE; PUTRESCINE; SPERMIDINE; SPERMINE; SPERMINE DERIVATIVE;

AMINE TRANSPORT; ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL GROWTH; CELL PROLIFERATION; CHO CELL; COMPETITIVE INHIBITION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MEMBRANE PERMEABILITY; NONHUMAN; POLYAMINE SYNTHESIS; PRIORITY JOURNAL; TRANSPORT KINETICS;

ANIMALS; BREAST NEOPLASMS; CELL DIVISION; CELL MEMBRANE; CHO CELLS; CRICETINAE; CYCLOHEXIMIDE; CYSTEAMINE; DISULFIDES; FEMALE; HUMANS; INDICATORS AND REAGENTS; KINETICS; MOLECULAR STRUCTURE; POLYAMINES; PUTRESCINE; SPERMIDINE; SPERMINE; STRUCTURE-ACTIVITY RELATIONSHIP; SULFHYDRYL COMPOUNDS; TUMOR CELLS, CULTURED;

ANIMALIA; MAMMALIA;

EID: 0029861522     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.44.27556     Document Type: Article

References (59)

1. Pegg, A. E. (1988) Cancer Res. 48, 759-774
2. Tabor, C. W., and Tabor, H. (1984) Annu. Rev. Biochem. 53, 749-790
3. Marton, L. J., and Pegg, A. E. (1995) Annu. Rev. Pharmacol. Toxicol. 35, 55-91
4. Seiler, N., and Dezeure, F. (1990) Int. J. Biochem. 22, 211-218
5. Pegg, A. E., Poulin, R, and Coward, J. K. (1995) Int. J. Biochem. Cell. Biol. 27, 425-442
6. Byers, T. L., and Pegg, A. E. (1990) J. Cell. Physiol. 143, 460-467
7. Poulin, R., Lu, L., Ackermann, B., Bey, P., and Pegg. A. E. (1992) J. Biol. Chem. 267, 150-158
8. Sarhan, S., Knödgen, B., and Seiler, N. (1989) Anticancer Res. 9, 215-224
9. Hessels, J., Kingma, A. W., Ferwerda, H., Keij, J., Van der Berg, G. A., and Muskiet, F. A. J. (1989) Int. J. Cancer 43, 1115-1166
10. Ask, A., Persson, L., and Heby, O. (1992) Cancer Lett. 66, 29-34
11. Seiler, N., Sarhan, S., Grauffel, C., Jones, R., Knödgen, B., and Moulinoux, J.-P. (1990) Cancer Res. 50, 5077-5083
12. Persson, L., Holm, I., Ask, A., and Heby, O. (1988) Cancer Res. 48, 4807-4811
13. Behr, J. P. (1989) J. Chem. Soc. Chem. Commun. 101-103
14. Bergeron, R. J., and Garlich, J. R. (1984) Synthesis 782-784
15. Ponnusamy, E., Fotadar, U., Spisni, A., and Fiat, D. (1986) Synthesis, 48-49
16. Venkataraman, K. (1979) Tetrahedron Lett. 32, 3037
17. Jocelyn, P. C. (1987) Methods Enzymol. 143, 44-67
18. Pegg, A. E., Wechter, R., Poulin, R., Woster, P. M., and Coward, J. K. (1989) Biochemistry 28, 8446-8453
19. Huber, M., and Poulin, R. (1995) Cancer Res. 55, 934-943
20. Morgan, D. M. L. (1989) in The Physiology of Polyamines (Bachrach, U., and Heimer, Y. M., eds) Vol. I, pp. 203-229, CRC Press, Inc., Boca Raton, FL
21. Simard, J., Dauvois, S., Haagensen, D. E., Lévesque, C., Mérand, Y., and Labrie, F. (1990) Endocrinology 126, 3223-3231
22. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. (1951) J. Biol. Chem. 193, 265-275
23. Lessard, M., Zhao, C., Singh. S. M., and Poulin, R. (1995) J. Biol. Chem. 270, 1685-1694
24. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
25. Dixon, M., and Webb, E. C. (1976) Enzymes 3rd Ed., Academic Press, San Diego, CA
26. Torossian. K., Audette, M., and Poulin, R. (1996) Biochem. J. 319, 21-26
27. Bergeron, R. J., and Seligsohn, H. W. (1986) Bioinorg. Chem. 14, 345-355
28. Porter, C. W., Cavanaugh, P. F., Jr., Stolowich, N., Ganis, B., Kelly, E., and Bergeron, R. J. (1985) Cancer Res. 45, 2050-2057
29. Porter, C. W., Bergeron, R. J., and Stolowich, N. J. (1982) Cancer Res. 42, 4072-4078
30. Porter, C. W., and Bergeron, R. J. (1983) Science 219, 1083-1085
31. Basu, H. S., Feuerstein, B. G., Deen, D. F., Lubich, W. P., Bergeron, R. J., Samejima, K., and Marton, L. J. (1989) Cancer Res. 49, 5591-5597
32. Pegg, A. E., Wechter, R., Pakala, R., and Bergeron, R. J. (1989) J. Biol Chem. 264, 11744-11749
33. Pegg, A. E., Nagarajan, S., Naficy, S., and Ganem, B. (1991 ) Biochem. J. 274, 167-171
34. Porter, C. W., Ganis, B., Libby, P. R., and Bergeron, R. J. (1991) Cancer Res. 51, 3715-3720
35. Mitchell, J. L. A., Diveley, R. R., Jr., and Bareyal-Leyser, A. (1992) Biochem. Biophys. Res. Commun. 186, 81-88
36. Seiler, N. (1987) in Inhibition of Polyamine Metabolism: Biological Significance and Basis for New Therapies (McCann, P. P., Pegg, A. E., and Sjoerdsma, A., eds) pp. 49-77, Academic Press, Inc., Orlando, FL
37. Blaschko, H., and Hawes, R. (1959) J. Physiol. 145, 124-131
38. Smith, L. L., and Wyatt, I. (1981) Biochem. Pharmacol. 30, 1053-1058
39. Rannels, D. E., Pegg, A. E., Clark, R. S., and Addison, J. L. (1985) Am. J. Physiol. 249, E506-E513
40. Minchin, R. F., Martin, R. L., Summers, L. A., and Ilett, K. F. (1989) Biochem. J. 262, 391-395
41. Aziz, S. M., Tofiq, S. F., Gosland, M. P., Olson, J. W., and Gillespie, M. N. (1995) J. Pharmacol. Exp. Ther. 274, 181-196
42. Remy, J.-S., Kichler, A., Mordvinov, V., Schuber, F., and Behr. J.-P. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 1744-1748
43. Clark, A. E., and Holman, G. D. (1990) Biochem. J. 269, 615-622
44. Hebert, D. N., and Carruthers, A. (1992) J. Biol. Chem. 267, 23829-23838
45. Gould, G. W., and Holman, G. D. (1993) Biochem. J. 295, 329-341
46. Holley, J. L., Mather, A., Wheelhouse, R. T., Cullis, P. M., Hartley, J. A., Bingham, J. P., and Cohen, G. M. (1992) Cancer Rev. 52, 4190-4195
47. Gordonsmith, R. H., Brooke-Taylor, S., Smith, L. L., and Cohen, G. M. (1983) Biochem. Pharmacol. 32, 3701-3709
48. Moulinoux, J.-P., Quemener, V., and Khan, N. A. (1991) Cell. Mol. Biol 37, 773-783
49. Scalabrino, G., and Ferioli, M. E. (1981 ) Adv. Cancer Res. 36, 1-102
50. Bachrach, U. (1989) in The Physiology of Palyamines (Bachrach, U., and Heimer, Y. M., eds) Vol. II, pp. 235-249, CRC Press, Inc., Boca Raton, FL
51. Kakinuma, Y., Hoshino, K., and Igarashi, K. (1988) Eur. J. Biochem. 176, 409-414
52. Pegg, A. E., and McCann, P. P. (1982) Am. J. Physiol. 243, C212-C221
53. Mamont, P. S., Duchesne, M.-C., Grove, J., and Bey, P. (1978) Biochem. Biophys. Res. Commun. 81, 58-66
54. Felschow, D. M., MacDiarmid, J., Bardos, T., Wu, R., Woster, P. M., and Porter, C. W. (1995) J. Biol. Chem. 270, 28705-28711
55. Cooper, A. J. L. (1983) Annu. Rev. Biochem. 52, 187-222
56. Cavallini, D., De Marco, C., and Mondovi, B. (1956) Experientia 12, 377-379
57. Kawase, M., Samejima, K., and Okada, M. (1982) Biochem. Pharmacol. 31, 2983-2988
58. Brunton, V. G., Grant, M. H., and Wallace, H. M. (1990) Biochem. Pharmacol. 40, 1893-1900
59. Brüne, B., Hartzell, P., Nicotera, P., and Orrenius, S. (1991) Exp. Cell Res. 195, 323-329