Enhanced uptake of [3H] spermidine by 9L rat brain tumors after direct intratumoral infusion of inhibitors of enzymes of the polyamine biosynthetic pathway

Journal of Neuro-Oncology

Volumn 42, Issue 2, 1999, Pages 123-130

  Redgate, Edward S ^a   Grudziak, A G ^a   Deutsch, M ^a   Boggs, S S ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

9L glioma; Difluoromethylornithine (DFMO); MDL 73811 and 72527; Osmotic pumps; 3H Putrescine; 3H Spermidine

Indexed keywords

5' [(4 AMINO 2 BUTENYL)METHYLAMINO] 5' DEOXYADENOSINE; EFLORNITHINE; ENZYME INHIBITOR; N,N' BIS(2,3 BUTADIENYL)PUTRESCINE; POLYAMINE; PUTRESCINE; SPERMIDINE; TRITIUM; ADENOSYLMETHIONINE DECARBOXYLASE; DEOXYADENOSINE DERIVATIVE; DRUG DERIVATIVE; OXIDOREDUCTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN TUMOR; GLIOMA; INTRATUMORAL DRUG ADMINISTRATION; IONIZING RADIATION; MALE; NONHUMAN; OSMOTIC PUMP; POLYAMINE METABOLISM; POLYAMINE SYNTHESIS; RAT; SCINTILLATION COUNTING; ANIMAL; BODY WEIGHT; CELL CULTURE; CORPUS STRIATUM; DRUG ANTAGONISM; DRUG EFFECT; FISCHER 344 RAT; GLIOSARCOMA; INFUSION; METABOLISM; PATHOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

ADENOSYLMETHIONINE DECARBOXYLASE; ANIMALS; BIOLOGICAL TRANSPORT; BODY WEIGHT; BRAIN NEOPLASMS; CORPUS STRIATUM; DEOXYADENOSINES; EFLORNITHINE; ENZYME INHIBITORS; GLIOSARCOMA; INFUSIONS, PARENTERAL; MALE; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; PUTRESCINE; RATS; RATS, INBRED F344; SPERMIDINE; TRITIUM; TUMOR CELLS, CULTURED;

EID: 0032588882     PISSN: 0167594X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006108321223     Document Type: Article

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