메뉴 건너뛰기




Volumn 23, Issue 4, 2003, Pages 519-534

Flavonoids: Promising anticancer agents

Author keywords

Anticancer; Flavonoids; Mechanisms

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; ANTHOCYANIN; ANTINEOPLASTIC AGENT; APIGENIN; BIOCHANIN A; CATECHIN; CHALCONE DERIVATIVE; CHRYSIN; CIRSIMARITIN; CISPLATIN; CURCUMIN; DAIDZEIN; EPICATECHIN; FLAVANOL DERIVATIVE; FLAVANONE; FLAVONE DERIVATIVE; FLAVONOID; GENISTEIN; ISOFLAVAN DERIVATIVE; ISOQUERCITRIN; KAEMPFEROL; LUTEOLIN; MITOFLAXONE; MYRICETIN; NICOTIFLORIN; QUERCETIN; QUERCETIN 3 METHYL ETHER; SILYMARIN; SOPHORANONE; TANGERETIN; UNCLASSIFIED DRUG;

EID: 0038807711     PISSN: 01986325     EISSN: None     Source Type: Journal    
DOI: 10.1002/med.10033     Document Type: Review
Times cited : (1011)

References (133)
  • 1
    • 84892138934 scopus 로고
    • The impact of plant flavonoids on mammalian biology: Implications for immunity, inflammation and cancer
    • Harborne JB, editor. London: Chapman and Hall
    • Middleton E, Jr., Kandaswami C. The impact of plant flavonoids on mammalian biology: Implications for immunity, inflammation and cancer. In: Harborne JB, editor. The flavonoids advances in research since 1986. 1st edition. London: Chapman and Hall; 1994. p 619-652.
    • (1994) The Flavonoids Advances in Research Since 1986. 1st Edition , pp. 619-652
    • Middleton E., Jr.1    Kandaswami, C.2
  • 2
    • 0034736046 scopus 로고    scopus 로고
    • Advances in flavonoid research since 1992
    • Harborne JB, Williams CA. Advances in flavonoid research since 1992. Phytochemistry 2000;55:481-504.
    • (2000) Phytochemistry , vol.55 , pp. 481-504
    • Harborne, J.B.1    Williams, C.A.2
  • 3
    • 0032819772 scopus 로고    scopus 로고
    • Dietary flavonoids: Intake, health effects and bioavailability
    • Hollman PC, Katan MB. Dietary flavonoids: Intake, health effects and bioavailability. Food Chem Toxicol 1999;37:937-942.
    • (1999) Food Chem Toxicol , vol.37 , pp. 937-942
    • Hollman, P.C.1    Katan, M.B.2
  • 4
    • 0004580398 scopus 로고    scopus 로고
    • Flavonoids: Old and new aspects of a class of natural therapeutic drugs
    • Di Carlo G, Mascolo N, Izzo AA, Capasso F. Flavonoids: Old and new aspects of a class of natural therapeutic drugs. Life Sci 1999;65:337-353.
    • (1999) Life Sci , vol.65 , pp. 337-353
    • Di Carlo, G.1    Mascolo, N.2    Izzo, A.A.3    Capasso, F.4
  • 5
    • 0032817487 scopus 로고    scopus 로고
    • Health-promoting properties of common herbs
    • Craig WJ. Health-promoting properties of common herbs. Am J Clin Nutr 1999;70:491S-499S.
    • (1999) Am J Clin Nutr , vol.70
    • Craig, W.J.1
  • 8
    • 0033949036 scopus 로고    scopus 로고
    • The traditional uses, chemical constituents and biological activities of Plantago major L. A review
    • Samuelsen AB. The traditional uses, chemical constituents and biological activities of Plantago major L. A review. J Ethnopharmacol 2000;71:1-21.
    • (2000) J Ethnopharmacol , vol.71 , pp. 1-21
    • Samuelsen, A.B.1
  • 10
    • 0037142185 scopus 로고    scopus 로고
    • Sophoranone, extracted from a traditional Chinese medicine Shan Dou Gen, induces apoptosis in human leukemia U937 cells via formation of reactive oxygen species and opening of mitochondrial permeability transition pores
    • Kajimoto S, Takanashi N, Kajimoto T, Xu M, Cao J, Masuda Y, Aiuchi T, Nakajo S, Ida Y, Nakaya K, Sophoranone, extracted from a traditional Chinese medicine Shan Dou Gen, induces apoptosis in human leukemia U937 cells via formation of reactive oxygen species and opening of mitochondrial permeability transition pores. Int J Cancer 2002;99:879-890.
    • (2002) Int J Cancer , vol.99 , pp. 879-890
    • Kajimoto, S.1    Takanashi, N.2    Kajimoto, T.3    Xu, M.4    Cao, J.5    Masuda, Y.6    Aiuchi, T.7    Nakajo, S.8    Ida, Y.9    Nakaya, K.10
  • 11
  • 13
    • 0030695509 scopus 로고    scopus 로고
    • Cirsimarin and cirsimaritin, flavonoids of Microtea debilis (Phytolaccaceae) with adenosine antagonistic properties in rats: Leads for new therapeutics in acute renal failure
    • Hasrat JA, De Bruyne T, De Backer JP, Vauquelin G, Vlietinck AJ. Cirsimarin and cirsimaritin, flavonoids of Microtea debilis (Phytolaccaceae) with adenosine antagonistic properties in rats: Leads for new therapeutics in acute renal failure. J Pharm Pharmacol 1997;49:1150-1156.
    • (1997) J Pharm Pharmacol , vol.49 , pp. 1150-1156
    • Hasrat, J.A.1    De Bruyne, T.2    De Backer, J.P.3    Vauquelin, G.4    Vlietinck, A.J.5
  • 14
    • 0033637140 scopus 로고    scopus 로고
    • The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer
    • Middleton E, Jr., Kandaswami C, Theoharides TC. The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer. Pharmacol Rev 2000;52:673-751.
    • (2000) Pharmacol Rev , vol.52 , pp. 673-751
    • Middleton E., Jr.1    Kandaswami, C.2    Theoharides, T.C.3
  • 16
    • 0034928799 scopus 로고    scopus 로고
    • Inhibition of carcinogenesis by dietary polyphenolic compounds
    • Yang CS, Landau JM, Huang MT, Newmark HL. Inhibition of carcinogenesis by dietary polyphenolic compounds. Annu Rev Nutr 2001;21:381-406.
    • (2001) Annu Rev Nutr , vol.21 , pp. 381-406
    • Yang, C.S.1    Landau, J.M.2    Huang, M.T.3    Newmark, H.L.4
  • 17
    • 0034807826 scopus 로고    scopus 로고
    • Dietary agents in cancer prevention: Flavonoids and isoflavonoids
    • Birt DF, Hendrich S, Wang W. Dietary agents in cancer prevention: Flavonoids and isoflavonoids. Pharmacol Ther 2001;90:157-177.
    • (2001) Pharmacol Ther , vol.90 , pp. 157-177
    • Birt, D.F.1    Hendrich, S.2    Wang, W.3
  • 18
    • 0033855919 scopus 로고    scopus 로고
    • The therapeutic potential of flavonoids
    • Wang HK. The therapeutic potential of flavonoids. Expert Opin Invest Drugs 2000;9:2103-2119.
    • (2000) Expert Opin Invest Drugs , vol.9 , pp. 2103-2119
    • Wang, H.K.1
  • 19
    • 0036669812 scopus 로고    scopus 로고
    • Cancer preventive effects of flavonoids - A review
    • Le Marchand L. Cancer preventive effects of flavonoids - A review. Biomed Pharmacother 2002;56:296-301.
    • (2002) Biomed Pharmacother , vol.56 , pp. 296-301
    • Le Marchand, L.1
  • 26
    • 0033050025 scopus 로고    scopus 로고
    • Intake of specific carotenoids and flavonoids and the risk of gastric cancer in Spain
    • Garcia-Closas R, Gonzalez CA, Agudo A, Riboli E. Intake of specific carotenoids and flavonoids and the risk of gastric cancer in Spain. Cancer Causes Control 1999;10:71-75.
    • (1999) Cancer Causes Control , vol.10 , pp. 71-75
    • Garcia-Closas, R.1    Gonzalez, C.A.2    Agudo, A.3    Riboli, E.4
  • 27
    • 0036001343 scopus 로고    scopus 로고
    • Dietary catechins and cancer incidence among postmenopausal women: The Iowa Women's Health Study (United States)
    • Arts IC, Jacobs DR, Jr., Gross M, Harnack LJ, Folsom AR. Dietary catechins and cancer incidence among postmenopausal women: The Iowa Women's Health Study (United States). Cancer Causes Control 2002;13:373-382.
    • (2002) Cancer Causes Control , vol.13 , pp. 373-382
    • Arts, I.C.1    Jacobs D.R., Jr.2    Gross, M.3    Harnack, L.J.4    Folsom, A.R.5
  • 28
    • 0033500023 scopus 로고    scopus 로고
    • High intake of specific carotenoids and flavonoids does not reduce the risk of bladder cancer
    • Garcia R, Gonzalez CA, Agudo A, Riboli E. High intake of specific carotenoids and flavonoids does not reduce the risk of bladder cancer. Nutr Cancer 1999;35:212-214.
    • (1999) Nutr Cancer , vol.35 , pp. 212-214
    • Garcia, R.1    Gonzalez, C.A.2    Agudo, A.3    Riboli, E.4
  • 30
    • 0032454384 scopus 로고    scopus 로고
    • Intake of specific carotenoids and flavonoids and the risk of lung cancer in women in Barcelona, Spain
    • Garcia-Closas R, Agudo A, Gonzalez CA, Riboli E. Intake of specific carotenoids and flavonoids and the risk of lung cancer in women in Barcelona, Spain. Nutr Cancer 1998;32:154-158.
    • (1998) Nutr Cancer , vol.32 , pp. 154-158
    • Garcia-Closas, R.1    Agudo, A.2    Gonzalez, C.A.3    Riboli, E.4
  • 33
    • 18744438451 scopus 로고    scopus 로고
    • Induction of apoptosis by flavones, flavonols (3-hydroxyflavones) and isoprenoid-substituted flavonoids in human oral tumor cell lines
    • Sakagami H, Jiang Y, Kusama K, Atsumi T, Ueha T, Toguchi M, Iwakura I, Satoh K, Fukai T, Nomura T. Induction of apoptosis by flavones, flavonols (3-hydroxyflavones) and isoprenoid-substituted flavonoids in human oral tumor cell lines. Anticancer Res 2000;20:271-277.
    • (2000) Anticancer Res , vol.20 , pp. 271-277
    • Sakagami, H.1    Jiang, Y.2    Kusama, K.3    Atsumi, T.4    Ueha, T.5    Toguchi, M.6    Iwakura, I.7    Satoh, K.8    Fukai, T.9    Nomura, T.10
  • 34
    • 0033635638 scopus 로고    scopus 로고
    • Effect of tea polyphenols on growth of oral squamous carcinoma cells in vitro
    • Elattar TM, Virji AS. Effect of tea polyphenols on growth of oral squamous carcinoma cells in vitro. Anticancer Res 2000;20:3459-3465.
    • (2000) Anticancer Res , vol.20 , pp. 3459-3465
    • Elattar, T.M.1    Virji, A.S.2
  • 35
    • 0033856514 scopus 로고    scopus 로고
    • The inhibitory effect of curcumin, genistein, quercetin and cisplatin on the growth of oral cancer cells in vitro
    • Elattar TM, Virji AS. The inhibitory effect of curcumin, genistein, quercetin and cisplatin on the growth of oral cancer cells in vitro. Anticancer Res 2000;20:1733-1738.
    • (2000) Anticancer Res , vol.20 , pp. 1733-1738
    • Elattar, T.M.1    Virji, A.S.2
  • 37
    • 0034880971 scopus 로고    scopus 로고
    • Inhibition of environmental estrogen-induced proliferation of human breast carcinoma MCF-7 cells by flavonoids
    • Han D, Tachibana H, Yamada K. Inhibition of environmental estrogen-induced proliferation of human breast carcinoma MCF-7 cells by flavonoids. In Vitro Cell Dev Biol Anim 2001;37:275-282.
    • (2001) In Vitro Cell Dev Biol Anim , vol.37 , pp. 275-282
    • Han, D.1    Tachibana, H.2    Yamada, K.3
  • 38
    • 0032763752 scopus 로고    scopus 로고
    • Signal pathways involved in apigenin inhibition of growth and induction of apoptosis of human anaplastic thyroid cancer cells (ARO)
    • Yin F, Giuliano AE, Van Herle AJ. Signal pathways involved in apigenin inhibition of growth and induction of apoptosis of human anaplastic thyroid cancer cells (ARO). Anticancer Res 1999;19:4297-4303.
    • (1999) Anticancer Res , vol.19 , pp. 4297-4303
    • Yin, F.1    Giuliano, A.E.2    Van Herle, A.J.3
  • 39
    • 0033004673 scopus 로고    scopus 로고
    • Growth inhibitory effects of flavonoids in human thyroid cancer cell lines
    • Yin F, Giuliano AE, Van Herle AJ. Growth inhibitory effects of flavonoids in human thyroid cancer cell lines. Thyroid 1999;9:369-376.
    • (1999) Thyroid , vol.9 , pp. 369-376
    • Yin, F.1    Giuliano, A.E.2    Van Herle, A.J.3
  • 40
    • 0032538532 scopus 로고    scopus 로고
    • Promoter activation and following induction of the p21/WAF1 gene by flavone is involved in G1 phase arrest in A549 lung adenocarcinoma cells
    • Bai F, Matsui T, Ohtani-Fujita N, Matsukawa Y, Ding Y, Sakai T. Promoter activation and following induction of the p21/WAF1 gene by flavone is involved in G1 phase arrest in A549 lung adenocarcinoma cells. FEBS Lett 1998;437:61-64.
    • (1998) FEBS Lett , vol.437 , pp. 61-64
    • Bai, F.1    Matsui, T.2    Ohtani-Fujita, N.3    Matsukawa, Y.4    Ding, Y.5    Sakai, T.6
  • 43
    • 0035253312 scopus 로고    scopus 로고
    • Detrimental effect of cancer preventive phytochemicals silymarin, genistein and epigallocatechin 3-gallate on epigenetic events in human prostate carcinoma DU145 cells
    • Bhatia N, Agarwal R. Detrimental effect of cancer preventive phytochemicals silymarin, genistein and epigallocatechin 3-gallate on epigenetic events in human prostate carcinoma DU145 cells. Prostate 2001;46:98-107.
    • (2001) Prostate , vol.46 , pp. 98-107
    • Bhatia, N.1    Agarwal, R.2
  • 45
    • 0034668148 scopus 로고    scopus 로고
    • Cell signaling and regulators of cell cycle as molecular targets for prostate cancer prevention by dietary agents
    • Agarwal R. Cell signaling and regulators of cell cycle as molecular targets for prostate cancer prevention by dietary agents. Biochem Pharmacol 2000;60:1051-1059.
    • (2000) Biochem Pharmacol , vol.60 , pp. 1051-1059
    • Agarwal, R.1
  • 46
    • 0034660863 scopus 로고    scopus 로고
    • Dietary flavone is a potent apoptosis inducer in human colon carcinoma cells
    • Wenzel U, Kuntz S, Brendel MD, Daniel H. Dietary flavone is a potent apoptosis inducer in human colon carcinoma cells. Cancer Res 2000;60:3823-3831.
    • (2000) Cancer Res , vol.60 , pp. 3823-3831
    • Wenzel, U.1    Kuntz, S.2    Brendel, M.D.3    Daniel, H.4
  • 48
    • 0032815147 scopus 로고    scopus 로고
    • Comparative analysis of the effects of flavonoids on proliferation, cytotoxicity, and apoptosis in human colon cancer cell lines
    • Kuntz S, Wenzel U, Daniel H. Comparative analysis of the effects of flavonoids on proliferation, cytotoxicity, and apoptosis in human colon cancer cell lines. Eur J Nutr 1999;38:133-142.
    • (1999) Eur J Nutr , vol.38 , pp. 133-142
    • Kuntz, S.1    Wenzel, U.2    Daniel, H.3
  • 49
    • 0030872689 scopus 로고    scopus 로고
    • Effect of antiproliferative flavonoids on ascorbic acid accumulation in human colon adenocarcinoma cells
    • Kuo SM, Morehouse HF, Jr., Lin CP. Effect of antiproliferative flavonoids on ascorbic acid accumulation in human colon adenocarcinoma cells. Cancer Lett 1997;116:131-137.
    • (1997) Cancer Lett , vol.116 , pp. 131-137
    • Kuo, S.M.1    Morehouse H.F., Jr.2    Lin, C.P.3
  • 50
    • 0030596107 scopus 로고    scopus 로고
    • Antiproliferative potency of structurally distinct dietary flavonoids on human colon cancer cells
    • Kuo SM. Antiproliferative potency of structurally distinct dietary flavonoids on human colon cancer cells. Cancer Lett 1996;110:41-48.
    • (1996) Cancer Lett , vol.110 , pp. 41-48
    • Kuo, S.M.1
  • 51
    • 0032856994 scopus 로고    scopus 로고
    • Induction of apoptosis by apigenin and related flavonoids through cytochrome c release and activation of caspase-9 and caspase-3 in leukaemia HL-60 cells
    • Wang IK, Lin-Shiau SY, Lin JK. Induction of apoptosis by apigenin and related flavonoids through cytochrome c release and activation of caspase-9 and caspase-3 in leukaemia HL-60 cells. Eur J Cancer 1999;35:1517-1525.
    • (1999) Eur J Cancer , vol.35 , pp. 1517-1525
    • Wang, I.K.1    Lin-Shiau, S.Y.2    Lin, J.K.3
  • 53
    • 0030945675 scopus 로고    scopus 로고
    • Molecular mechanisms in the antiproliferative action of quercetin
    • Csokay B, Prajda N, Weber G, Olah E. Molecular mechanisms in the antiproliferative action of quercetin. Life Sci 1997;60:2157-2163.
    • (1997) Life Sci , vol.60 , pp. 2157-2163
    • Csokay, B.1    Prajda, N.2    Weber, G.3    Olah, E.4
  • 55
    • 0034280608 scopus 로고    scopus 로고
    • Flavonoids inhibit cell growth and induce apoptosis in B16 melanoma 4A5 cells
    • Iwashita K, Kobori M, Yamaki K, Tsushida T. Flavonoids inhibit cell growth and induce apoptosis in B16 melanoma 4A5 cells. Biosci Biotechnol Biochem 2000;64:1813-1820.
    • (2000) Biosci Biotechnol Biochem , vol.64 , pp. 1813-1820
    • Iwashita, K.1    Kobori, M.2    Yamaki, K.3    Tsushida, T.4
  • 56
    • 0028018410 scopus 로고
    • Natural flavonoids and lignans are potent cytostatic agents against human leukemic HL-60 cells
    • Hirano T, Gotoh M, Oka K. Natural flavonoids and lignans are potent cytostatic agents against human leukemic HL-60 cells. Life Sci 1994;55:1061-1069.
    • (1994) Life Sci , vol.55 , pp. 1061-1069
    • Hirano, T.1    Gotoh, M.2    Oka, K.3
  • 57
    • 0026326111 scopus 로고
    • Cytotoxicities of some flavonoid analogues
    • Cushman M, Nagarathnam D. Cytotoxicities of some flavonoid analogues. J Nat Prod 1991;54:1656-1660.
    • (1991) J Nat Prod , vol.54 , pp. 1656-1660
    • Cushman, M.1    Nagarathnam, D.2
  • 59
    • 0033917711 scopus 로고    scopus 로고
    • Inhibition of azoxymethane-induced colon cancer by orange juice
    • Miyagi Y, Om AS, Chee KM, Bennink MR. Inhibition of azoxymethane-induced colon cancer by orange juice. Nutr Cancer 2000;36:224-249.
    • (2000) Nutr Cancer , vol.36 , pp. 224-249
    • Miyagi, Y.1    Om, A.S.2    Chee, K.M.3    Bennink, M.R.4
  • 62
    • 0025885064 scopus 로고
    • Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia
    • Deschner EE, Ruperto J, Wong G, Newmark HL. Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia. Carcinogenesis 1991;12:1193-1196.
    • (1991) Carcinogenesis , vol.12 , pp. 1193-1196
    • Deschner, E.E.1    Ruperto, J.2    Wong, G.3    Newmark, H.L.4
  • 65
    • 0031588366 scopus 로고    scopus 로고
    • Chemopreventive effects of diosmin and hesperidin on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary-bladder carcinogenesis in male ICR mice
    • Yang M, Tanaka T, Hirose Y, Deguchi T, Mori H, Kawada Y. Chemopreventive effects of diosmin and hesperidin on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary-bladder carcinogenesis in male ICR mice. Int J Cancer 1997;73:719-724.
    • (1997) Int J Cancer , vol.73 , pp. 719-724
    • Yang, M.1    Tanaka, T.2    Hirose, Y.3    Deguchi, T.4    Mori, H.5    Kawada, Y.6
  • 66
    • 14444275051 scopus 로고    scopus 로고
    • Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis in rats by flavonoids diosmin and hesperidin, each alone and in combination
    • Tanaka T, Makita H, Ohnishi M, Mori H, Satoh K, Hara A, Sumida T, Fukutani K, Tanaka T, Ogawa H. Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis in rats by flavonoids diosmin and hesperidin, each alone and in combination. Cancer Res 1997;57:246-252.
    • (1997) Cancer Res , vol.57 , pp. 246-252
    • Tanaka, T.1    Makita, H.2    Ohnishi, M.3    Mori, H.4    Satoh, K.5    Hara, A.6    Sumida, T.7    Fukutani, K.8    Tanaka, T.9    Ogawa, H.10
  • 67
    • 0029946420 scopus 로고    scopus 로고
    • Chemoprevention of 4-nitroquinoline 1-oxide-induced rat oral carcinogenesis by the dietary flavonoids chalcone, 2-hydroxychalcone, and quercetin
    • Makita H, Tanaka T, Fujitsuka H, Tatematsu N, Satoh K, Hara A, Mori H. Chemoprevention of 4-nitroquinoline 1-oxide-induced rat oral carcinogenesis by the dietary flavonoids chalcone, 2-hydroxychalcone, and quercetin. Cancer Res 1996;56:4904-4909.
    • (1996) Cancer Res , vol.56 , pp. 4904-4909
    • Makita, H.1    Tanaka, T.2    Fujitsuka, H.3    Tatematsu, N.4    Satoh, K.5    Hara, A.6    Mori, H.7
  • 68
    • 0027939130 scopus 로고
    • Chemopreventive potential of dietary bioflavonoids against 20-methylcholanthrene-induced tumorigenesis
    • Elangovan V, Sekar N, Govindasamy S. Chemopreventive potential of dietary bioflavonoids against 20-methylcholanthrene-induced tumorigenesis. Cancer Lett 1994;87:107-113.
    • (1994) Cancer Lett , vol.87 , pp. 107-113
    • Elangovan, V.1    Sekar, N.2    Govindasamy, S.3
  • 69
    • 0034062589 scopus 로고    scopus 로고
    • Inhibitory effects of bifidobacterium-fermented soy milk on 2-amino-l-methyl-6-phenylimidaz[4,5-b]pyridine-induced rat mammary carcinogenesis, with a partial contribution of its component isoflavones
    • Ohta T, Nakatsugi S, Watanabe K, Kawamori T, Ishikawa F, Morotomi M, Sugie S, Toda T, Sugimura T, Wakabayashi K. Inhibitory effects of bifidobacterium-fermented soy milk on 2-amino-l-methyl-6-phenylimidaz[4,5-b]pyridine-induced rat mammary carcinogenesis, with a partial contribution of its component isoflavones. Carcinogenesis 2000;21:937-941.
    • (2000) Carcinogenesis , vol.21 , pp. 937-941
    • Ohta, T.1    Nakatsugi, S.2    Watanabe, K.3    Kawamori, T.4    Ishikawa, F.5    Morotomi, M.6    Sugie, S.7    Toda, T.8    Sugimura, T.9    Wakabayashi, K.10
  • 70
    • 0030000421 scopus 로고    scopus 로고
    • Inhibitory effect of dietary flavonol quercetin on 7,12-dimethylbanz[a]anthracene-induced hamster buccal pouch carcingoenesis
    • Balasubramanian S, Govindasamy S. Inhibitory effect of dietary flavonol quercetin on 7,12-dimethylbanz[a]anthracene-induced hamster buccal pouch carcingoenesis. Carcinogenesis 1996;17:877-879.
    • (1996) Carcinogenesis , vol.17 , pp. 877-879
    • Balasubramanian, S.1    Govindasamy, S.2
  • 71
    • 0023681264 scopus 로고
    • Inhibition of 7,12 dimethylbenz(a) anthracene and N-nitrosomethylurea induced rat mammary cancer by dietary flavonol quercetin
    • Verma AK, Johnson JA, Gould MN, Tanner MA. Inhibition of 7,12 dimethylbenz(a) anthracene and N-nitrosomethylurea induced rat mammary cancer by dietary flavonol quercetin. Cancer Res 1988;48:5754-5758.
    • (1988) Cancer Res , vol.48 , pp. 5754-5758
    • Verma, A.K.1    Johnson, J.A.2    Gould, M.N.3    Tanner, M.A.4
  • 72
    • 0032782963 scopus 로고    scopus 로고
    • Prevention of N-nitrosodiethylamine-induced lung tumorigenesis by ellagic acid and quercetin in mice
    • Khanduja KL, Gandhi RK, Pathania V, Syal N. Prevention of N-nitrosodiethylamine-induced lung tumorigenesis by ellagic acid and quercetin in mice. Food Chem Toxicol 1999;37:313-318.
    • (1999) Food Chem Toxicol , vol.37 , pp. 313-318
    • Khanduja, K.L.1    Gandhi, R.K.2    Pathania, V.3    Syal, N.4
  • 73
    • 0029648971 scopus 로고
    • Modulating effects of ellagic acid, vanillin and quercetin in a rat medium term multi-organ carcingoenesis model
    • Akagi K, Hirose M, Hoshiya T, Mizoguchi Y, Ito N, Shirai T. Modulating effects of ellagic acid, vanillin and quercetin in a rat medium term multi-organ carcingoenesis model. Cancer Lett 1995;94:113-121.
    • (1995) Cancer Lett , vol.94 , pp. 113-121
    • Akagi, K.1    Hirose, M.2    Hoshiya, T.3    Mizoguchi, Y.4    Ito, N.5    Shirai, T.6
  • 77
    • 0036173982 scopus 로고    scopus 로고
    • Inhibition of activator protein-1 binding activity and phosphatidylinositol 3-kinase pathway by nobiletin, a polymethoxy flavonoid, results in augmentation of tissue inhibitor of metalloproteinases-1 production and suppression of production of matrix metalloproteinases-1 and -9 in human fibrosarcoma HT-1080 cells
    • Sato T, Koike L, Miyata Y, Hirata M, Mimaki Y, Sashida Y, Yano M, Ito A. Inhibition of activator protein-1 binding activity and phosphatidylinositol 3-kinase pathway by nobiletin, a polymethoxy flavonoid, results in augmentation of tissue inhibitor of metalloproteinases-1 production and suppression of production of matrix metalloproteinases-1 and -9 in human fibrosarcoma HT-1080 cells. Cancer Res 2002;62:1025-1029.
    • (2002) Cancer Res , vol.62 , pp. 1025-1029
    • Sato, T.1    Koike, L.2    Miyata, Y.3    Hirata, M.4    Mimaki, Y.5    Sashida, Y.6    Yano, M.7    Ito, A.8
  • 78
    • 0035687569 scopus 로고    scopus 로고
    • Suppression by apigenin of peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane in Wistar rats
    • Tatsuta A, Iishi H, Baba M, Yano H, Murata K, Mukai M, Akedo H. Suppression by apigenin of peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane in Wistar rats. Clin Exp Metastasis 2000;18:657-662.
    • (2000) Clin Exp Metastasis , vol.18 , pp. 657-662
    • Tatsuta, A.1    Iishi, H.2    Baba, M.3    Yano, H.4    Murata, K.5    Mukai, M.6    Akedo, H.7
  • 82
    • 0033375469 scopus 로고    scopus 로고
    • Flavopiridol: The first cyclin-dependent kinase inhibitor in human clinical trials
    • Senderowicz AM. Flavopiridol: The first cyclin-dependent kinase inhibitor in human clinical trials. Invest New Drugs 1999;17:313-320.
    • (1999) Invest New Drugs , vol.17 , pp. 313-320
    • Senderowicz, A.M.1
  • 83
    • 0035141075 scopus 로고    scopus 로고
    • Development of cyclin-dependent kinase modulators as novel therapeutic approaches for hematological malignancies
    • Senderowicz AM. Development of cyclin-dependent kinase modulators as novel therapeutic approaches for hematological malignancies. Leukemia 2001;15:1-9.
    • (2001) Leukemia , vol.15 , pp. 1-9
    • Senderowicz, A.M.1
  • 84
    • 0034868715 scopus 로고    scopus 로고
    • Flavopiridol
    • National Cancer Institute
    • Wang HK. Flavopiridol. National Cancer Institute. Curr Opin Investig Drugs 2001;2:1149-1155.
    • (2001) Curr Opin Investig Drugs , vol.2 , pp. 1149-1155
    • Wang, H.K.1
  • 85
    • 0026590679 scopus 로고
    • Inhibition of carcinogenesis by minor dietary constituents
    • Wattenberg LW. Inhibition of carcinogenesis by minor dietary constituents. Cancer Res 1992;52:2085s-2091s.
    • (1992) Cancer Res , vol.52
    • Wattenberg, L.W.1
  • 87
    • 0032998224 scopus 로고    scopus 로고
    • Cancer chemopreventive mechanisms of tea against heterocyclic amine mutagens from cooked meat
    • Dashwood RH, Xu M, Hernaez JF, Hasaniya N, Youn K, Razzuk A. Cancer chemopreventive mechanisms of tea against heterocyclic amine mutagens from cooked meat. Proc Soc Exp Biol Med 1999;220:239-243.
    • (1999) Proc Soc Exp Biol Med , vol.220 , pp. 239-243
    • Dashwood, R.H.1    Xu, M.2    Hernaez, J.F.3    Hasaniya, N.4    Youn, K.5    Razzuk, A.6
  • 88
    • 0031958338 scopus 로고    scopus 로고
    • Glucosinolates and phenolics as antioxidants from plant foods
    • Williamson G, Faulkner K, Plumb GW. Glucosinolates and phenolics as antioxidants from plant foods. Eur J Cancer Prev 1998;7:17-21.
    • (1998) Eur J Cancer Prev , vol.7 , pp. 17-21
    • Williamson, G.1    Faulkner, K.2    Plumb, G.W.3
  • 89
    • 0002254648 scopus 로고    scopus 로고
    • Anticancer properties of flavonoids, with emphasis on citrus flavonoids
    • Rice-Evans CA, Packer L, editors. New York: Marcel Dekker Inc.
    • Carroll KK, Guthrie N, So FV, Chambers AF. Anticancer properties of flavonoids, with emphasis on citrus flavonoids. In: Rice-Evans CA, Packer L, editors. Flavonoids in health and disease. New York: Marcel Dekker Inc.; 1998. p 437-446.
    • (1998) Flavonoids in Health and Disease , pp. 437-446
    • Carroll, K.K.1    Guthrie, N.2    So, F.V.3    Chambers, A.F.4
  • 90
    • 0033082440 scopus 로고    scopus 로고
    • A flavonoid antioxidant, silymarin, affords exceptionally high protection against tumor promotion in the SENCAR mouse skin tumorigenesis model
    • Lahiri-Chatterjee M, Katiyar SK, Mohan RR, Agarwal R. A flavonoid antioxidant, silymarin, affords exceptionally high protection against tumor promotion in the SENCAR mouse skin tumorigenesis model. Cancer Res 1999;59:622-632.
    • (1999) Cancer Res , vol.59 , pp. 622-632
    • Lahiri-Chatterjee, M.1    Katiyar, S.K.2    Mohan, R.R.3    Agarwal, R.4
  • 91
    • 0028268359 scopus 로고
    • Isozyme- and species-specific susceptibility of cDNA-expressed CYP1A P-450s to different flavonoids
    • Tsyrlov IB, Mikhailenko VM, Gelboin HV. Isozyme- and species-specific susceptibility of cDNA-expressed CYP1A P-450s to different flavonoids. Biochim Biophys Acta 1994;1205:325-335.
    • (1994) Biochim Biophys Acta , vol.1205 , pp. 325-335
    • Tsyrlov, I.B.1    Mikhailenko, V.M.2    Gelboin, H.V.3
  • 92
    • 0031825823 scopus 로고    scopus 로고
    • Contribution of caffeine and flavanols in the induction of hepatic Phase II activities by green tea
    • Bu-Abbas A, Clifford MN, Walker R, Ioannides C. Contribution of caffeine and flavanols in the induction of hepatic Phase II activities by green tea. Food Chem Toxicol 1998;36:617-621.
    • (1998) Food Chem Toxicol , vol.36 , pp. 617-621
    • Bu-Abbas, A.1    Clifford, M.N.2    Walker, R.3    Ioannides, C.4
  • 93
    • 0032100644 scopus 로고    scopus 로고
    • Increased UDP-glucuronosyltransferase activity and decreased prostate specific antigen production by biochanin A in prostate cancer cells
    • Sun XY, Plouzek CA, Henry JP, Wang TT, Phang JM. Increased UDP-glucuronosyltransferase activity and decreased prostate specific antigen production by biochanin A in prostate cancer cells. Cancer Res 1998;58:2379-2384.
    • (1998) Cancer Res , vol.58 , pp. 2379-2384
    • Sun, X.Y.1    Plouzek, C.A.2    Henry, J.P.3    Wang, T.T.4    Phang, J.M.5
  • 94
    • 0035464108 scopus 로고    scopus 로고
    • Aromatase, aromatase inhibitors, and breast cancer
    • Brueggemeier RW. Aromatase, aromatase inhibitors, and breast cancer. Am J Ther 2001;8:333-344.
    • (2001) Am J Ther , vol.8 , pp. 333-344
    • Brueggemeier, R.W.1
  • 98
    • 0027742757 scopus 로고
    • Inhibitory effects of flavonoids on xanthine oxidase
    • Chang WS, Lee YJ, Lu FJ, Chiang HC. Inhibitory effects of flavonoids on xanthine oxidase. Anticancer Res 1993;13:2165-2170.
    • (1993) Anticancer Res , vol.13 , pp. 2165-2170
    • Chang, W.S.1    Lee, Y.J.2    Lu, F.J.3    Chiang, H.C.4
  • 99
    • 0028983181 scopus 로고
    • Structure-activity relationship of caffeic acid analogues on xanthine oxidase inhibition
    • Chan WS, Wen PC, Chiang HC. Structure-activity relationship of caffeic acid analogues on xanthine oxidase inhibition. Anticancer Res 1995;15:703-707.
    • (1995) Anticancer Res , vol.15 , pp. 703-707
    • Chan, W.S.1    Wen, P.C.2    Chiang, H.C.3
  • 102
    • 0031394645 scopus 로고    scopus 로고
    • Suppression of protein kinase C and nuclear oncogene expression as possible molecular mechanisms of cancer chemoprevention by apigenin and curcumin
    • Lin JK, Chen YC, Huang YT, Lin-Shiau SY. Suppression of protein kinase C and nuclear oncogene expression as possible molecular mechanisms of cancer chemoprevention by apigenin and curcumin. J Cell Biochem Suppl 1997;28-29:39-48.
    • (1997) J Cell Biochem Suppl , vol.28-29 , pp. 39-48
    • Lin, J.K.1    Chen, Y.C.2    Huang, Y.T.3    Lin-Shiau, S.Y.4
  • 104
    • 0031921546 scopus 로고    scopus 로고
    • Anticarcinogenic effect of a flavonoid antioxidant, silymarin, in human breast cancer cells MDA-MB 468: Induction of G1 arrest through an increase in Cipl/p21 concomitant with a decrease in kinase activity of cyclin-dependent kinases and associated cyclins
    • Zi X, Feyes DK, Agarwal R. Anticarcinogenic effect of a flavonoid antioxidant, silymarin, in human breast cancer cells MDA-MB 468: Induction of G1 arrest through an increase in Cipl/p21 concomitant with a decrease in kinase activity of cyclin-dependent kinases and associated cyclins. Clin Cancer Res 1998;4:1055-1064.
    • (1998) Clin Cancer Res , vol.4 , pp. 1055-1064
    • Zi, X.1    Feyes, D.K.2    Agarwal, R.3
  • 106
    • 0035874028 scopus 로고    scopus 로고
    • Effects of structurally related flavonoids on cell cycle progression of human melanoma cells: Regulation of cyclin-dependent kinases CDK2 and CDK1
    • Casagrande F, Darbon JM. Effects of structurally related flavonoids on cell cycle progression of human melanoma cells: Regulation of cyclin-dependent kinases CDK2 and CDK1. Biochem Pharmacol 2001;61:1205-1215.
    • (2001) Biochem Pharmacol , vol.61 , pp. 1205-1215
    • Casagrande, F.1    Darbon, J.M.2
  • 107
    • 0034040082 scopus 로고    scopus 로고
    • Topoisomerase I poisons and suppressors as anticancer drugs
    • Bailly C. Topoisomerase I poisons and suppressors as anticancer drugs. Curr Med Chem 2000;7:39-58.
    • (2000) Curr Med Chem , vol.7 , pp. 39-58
    • Bailly, C.1
  • 108
    • 0034457331 scopus 로고    scopus 로고
    • Cytotoxic mechanism of flavonoid from Temu Kunci (Kaempferia pandurata) in cell culture of human mammary carcinoma
    • Sukardiman, Darwanto A, Tanjung M, Darmadi MO. Cytotoxic mechanism of flavonoid from Temu Kunci (Kaempferia pandurata) in cell culture of human mammary carcinoma. Clin Hemorheol Microcirc 2000;23:185-190.
    • (2000) Clin Hemorheol Microcirc , vol.23 , pp. 185-190
    • Sukardiman1    Darwanto, A.2    Tanjung, M.3    Darmadi, M.O.4
  • 109
    • 0037081782 scopus 로고    scopus 로고
    • Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca(2+)-dependent endonuclease
    • Lee WR, Shen SC, Lin HY, Hou WC, Yang LL, Chen YC. Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca(2+)-dependent endonuclease. Biochem Pharmacol 2002;63:225-236.
    • (2002) Biochem Pharmacol , vol.63 , pp. 225-236
    • Lee, W.R.1    Shen, S.C.2    Lin, H.Y.3    Hou, W.C.4    Yang, L.L.5    Chen, Y.C.6
  • 110
    • 0034480641 scopus 로고    scopus 로고
    • Quercetin-induced apoptosis in the monoblastoid cell line U937 in vitro and the regulation of heat shock proteins expression
    • Rong Y, Yang EB, Zhang K, Mack P. Quercetin-induced apoptosis in the monoblastoid cell line U937 in vitro and the regulation of heat shock proteins expression. Anticancer Res 2000;20:4339-4345.
    • (2000) Anticancer Res , vol.20 , pp. 4339-4345
    • Rong, Y.1    Yang, E.B.2    Zhang, K.3    Mack, P.4
  • 111
    • 0040932434 scopus 로고    scopus 로고
    • The novel cyclin-dependent kinase inhibitor flavopiridol downregulates Bcl-2 and induces growth arrest and apoptosis in chronic B-cell leukemia lines
    • Konig A, Schwartz GK, Mohammad RM, Al-Katib A, Gabrilove JL. The novel cyclin-dependent kinase inhibitor flavopiridol downregulates Bcl-2 and induces growth arrest and apoptosis in chronic B-cell leukemia lines. Blood 1997;90:4307-4312.
    • (1997) Blood , vol.90 , pp. 4307-4312
    • Konig, A.1    Schwartz, G.K.2    Mohammad, R.M.3    Al-Katib, A.4    Gabrilove, J.L.5
  • 113
    • 0005452850 scopus 로고    scopus 로고
    • Two flavonoids from the leaves of Morus alba induce differentiation of the human promyelocytic leukemia (HL-60) cell line
    • Kim SY, Gao JJ, Kang HK. Two flavonoids from the leaves of Morus alba induce differentiation of the human promyelocytic leukemia (HL-60) cell line. Biol Pharm Bull 2000;23:451-455.
    • (2000) Biol Pharm Bull , vol.23 , pp. 451-455
    • Kim, S.Y.1    Gao, J.J.2    Kang, H.K.3
  • 115
    • 0032200397 scopus 로고    scopus 로고
    • Structure-activity relationships of flavonoids and the induction of granulocytic- or monocytic-differentiation in HL60 human myeloid leukemia cells
    • Takahashi T, Kobori M, Shinmoto H, Tsushida T. Structure-activity relationships of flavonoids and the induction of granulocytic- or monocytic-differentiation in HL60 human myeloid leukemia cells. Biosci Biotechnol Biochem 1998;62:2199-2204.
    • (1998) Biosci Biotechnol Biochem , vol.62 , pp. 2199-2204
    • Takahashi, T.1    Kobori, M.2    Shinmoto, H.3    Tsushida, T.4
  • 116
    • 0027303635 scopus 로고
    • Differentiation of promyelocytic leukemia cells HL-60 induced by daidzein in vitro and in vivo
    • Jing Y, Nakaya K, Han R. Differentiation of promyelocytic leukemia cells HL-60 induced by daidzein in vitro and in vivo. Anticancer Res 1993;13:1049-1054.
    • (1993) Anticancer Res , vol.13 , pp. 1049-1054
    • Jing, Y.1    Nakaya, K.2    Han, R.3
  • 117
    • 0025243674 scopus 로고
    • Inhibition of abl oncogene tyrosine kinase induces erythroid differentiation of human myelogenous leukemia K562 cells
    • Honma Y, Okabe-Kado J, Kasukabe T, Hozumi M, Umezawa K. Inhibition of abl oncogene tyrosine kinase induces erythroid differentiation of human myelogenous leukemia K562 cells. Jpn J Cancer Res 1990;81:1132-1136.
    • (1990) Jpn J Cancer Res , vol.81 , pp. 1132-1136
    • Honma, Y.1    Okabe-Kado, J.2    Kasukabe, T.3    Hozumi, M.4    Umezawa, K.5
  • 118
    • 0025363503 scopus 로고
    • Induction of differentiation and DNA strand breakage in human HL-60 and K-562 leukemia cells by genistein
    • Constantinou A, Kiguchi K, Huberman E. Induction of differentiation and DNA strand breakage in human HL-60 and K-562 leukemia cells by genistein. Cancer Res 1990;50:2618-2624.
    • (1990) Cancer Res , vol.50 , pp. 2618-2624
    • Constantinou, A.1    Kiguchi, K.2    Huberman, E.3
  • 119
    • 0028644238 scopus 로고
    • Free radical scavenging and antioxidant activity of plant flavonoids
    • Kandaswami C, Middleton E, Jr. Free radical scavenging and antioxidant activity of plant flavonoids. Adv Exp Med Biol 1994;366:351-376.
    • (1994) Adv Exp Med Biol , vol.366 , pp. 351-376
    • Kandaswami, C.1    Middleton E., Jr.2
  • 120
    • 0025126555 scopus 로고
    • Role of free radicals and catalytic metal ions in human disease: An overview
    • Halliwell B, Gutteridge JM. Role of free radicals and catalytic metal ions in human disease: An overview. Methods Enzymol 1990;186:1-85.
    • (1990) Methods Enzymol , vol.186 , pp. 1-85
    • Halliwell, B.1    Gutteridge, J.M.2
  • 121
    • 0026636441 scopus 로고
    • Free radicals, antioxidants, and human disease: Where are we now?
    • Halliwell B, Gutteridge JMC, Cross CE. Free radicals, antioxidants, and human disease: Where are we now? J Lab Clin Med 1992;119:598-620.
    • (1992) J Lab Clin Med , vol.119 , pp. 598-620
    • Halliwell, B.1    Gutteridge, J.M.C.2    Cross, C.E.3
  • 122
    • 0033021259 scopus 로고    scopus 로고
    • Dietary flavonoids protect human colonocyte DNA from oxidative attack in vitro
    • Duthie SJ, Dobson VL. Dietary flavonoids protect human colonocyte DNA from oxidative attack in vitro. Eur J Nutr 1999;38:28-34.
    • (1999) Eur J Nutr , vol.38 , pp. 28-34
    • Duthie, S.J.1    Dobson, V.L.2
  • 123
    • 0033082824 scopus 로고    scopus 로고
    • Antioxidant property of dietary phenolic agents in a human LDL-oxidation ex vivo model: Interaction of protein binding activity
    • Wang W, Goodman MT. Antioxidant property of dietary phenolic agents in a human LDL-oxidation ex vivo model: Interaction of protein binding activity. Nutr Res 1999;19:191-202.
    • (1999) Nutr Res , vol.19 , pp. 191-202
    • Wang, W.1    Goodman, M.T.2
  • 124
    • 0032421377 scopus 로고    scopus 로고
    • Natural products as angiogenesis inhibitors
    • Paper DH. Natural products as angiogenesis inhibitors. Planta Med 1998;64:686-695.
    • (1998) Planta Med , vol.64 , pp. 686-695
    • Paper, D.H.1
  • 125
    • 0036136731 scopus 로고    scopus 로고
    • Angioprevention': Angiogenesis is a common and key target for cancer chemopreventive agents
    • Tosetti F, Ferrari N, De Flora S, Albini A. Angioprevention': Angiogenesis is a common and key target for cancer chemopreventive agents. FASEB J 2002;16:2-14.
    • (2002) FASEB J , vol.16 , pp. 2-14
    • Tosetti, F.1    Ferrari, N.2    De Flora, S.3    Albini, A.4
  • 127
    • 0026504102 scopus 로고
    • Quercetin, a bioflavonoid, inhibits the increase of human multidrug resistance gene (MDR 1) expression caused by arsenite
    • Kioka M, Hosokawa N, Komano T, Hirayoshi K, Nagata K, Ueda K. Quercetin, a bioflavonoid, inhibits the increase of human multidrug resistance gene (MDR 1) expression caused by arsenite. FEBS Lett 1992;301:307-309.
    • (1992) FEBS Lett , vol.301 , pp. 307-309
    • Kioka, M.1    Hosokawa, N.2    Komano, T.3    Hirayoshi, K.4    Nagata, K.5    Ueda, K.6
  • 128
    • 0032840529 scopus 로고    scopus 로고
    • P-glycoprotein-mediated resistance to chemotherapy in cancer cells: Using recombinant cytosolic domains to establish structure-function relationships
    • Di Pietro A, Dayan G, Conseil G, Steinfels E, Krell T, Trompier D, Baubichon-Cortay H, Jault J. P-glycoprotein-mediated resistance to chemotherapy in cancer cells: Using recombinant cytosolic domains to establish structure-function relationships. Braz J Med Biol Res 1999;32:925-939.
    • (1999) Braz J Med Biol Res , vol.32 , pp. 925-939
    • Di Pietro, A.1    Dayan, G.2    Conseil, G.3    Steinfels, E.4    Krell, T.5    Trompier, D.6    Baubichon-Cortay, H.7    Jault, J.8
  • 129
    • 0031581819 scopus 로고    scopus 로고
    • Effect of quercetin on Hoechst 33342 transport by purified and reconstituted P-glycoprotein
    • Shapiro AB, Ling V. Effect of quercetin on Hoechst 33342 transport by purified and reconstituted P-glycoprotein. Biochem Pharmacol 1997;53:587-596.
    • (1997) Biochem Pharmacol , vol.53 , pp. 587-596
    • Shapiro, A.B.1    Ling, V.2
  • 131
    • 0034988902 scopus 로고    scopus 로고
    • Treatment with inhibitors of caspases, that are substrates of drug transporters, selectively permits chemotherapy-induced apoptosis in multidrug-resistant cells but protects normal cells
    • Blagosklonny MV. Treatment with inhibitors of caspases, that are substrates of drug transporters, selectively permits chemotherapy-induced apoptosis in multidrug-resistant cells but protects normal cells. Leukemia 2001;15:936-941.
    • (2001) Leukemia , vol.15 , pp. 936-941
    • Blagosklonny, M.V.1
  • 132
    • 0034599915 scopus 로고    scopus 로고
    • Efficacies of tea components on doxombicin induced antitumor activity and reversal of multidrug resistance
    • Sadzuka Y, Sugiyama T, Sonobe T. Efficacies of tea components on doxombicin induced antitumor activity and reversal of multidrug resistance. Toxicol Lett 2000;114:155-162.
    • (2000) Toxicol Lett , vol.114 , pp. 155-162
    • Sadzuka, Y.1    Sugiyama, T.2    Sonobe, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.