Detrimental effect of cancer preventive phytochemicals silymarin, genistein and epigallocatechin 3-gallate on epigenetic events in human prostate carcinoma DU145 cells

Prostate

Volumn 46, Issue 2, 2001, Pages 98-107

  Bhatia, Neehar ^a   Agarwal, Rajesh ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO CANCER CENTER   (United States)

Author keywords

Cell cycle; EGCG; EGFR; Genistein; MAPK; Silymarin

Indexed keywords

CYCLIN D1; CYCLIN E; CYCLINE; EPIGALLOCATECHIN GALLATE; GENISTEIN; SILYMARIN; TRYPAN BLUE;

ARTICLE; BINDING AFFINITY; CANCER CELL; CANCER GENETICS; CANCER PREVENTION; CELL CULTURE; CELL CYCLE G1 PHASE; CELL DEATH; CELL GROWTH; CELL LYSATE; CELL VIABILITY; CYTOTOXICITY; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MALE; PHYTOCHEMISTRY; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN BINDING; WESTERN BLOTTING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANTICARCINOGENIC AGENTS; CATECHIN; CELL CYCLE; CELL DEATH; CELL DIVISION; GENISTEIN; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; PLANT EXTRACTS; PROSTATIC NEOPLASMS; PROTEIN BINDING; PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SILYMARIN; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 0035253312     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0045(20010201)46:2<98::AID-PROS1013>3.0.CO;2-K     Document Type: Article

References (38)

1. Cancer statistics 2000
2. Androgen deprivation as a strategy for prostate cancer chemoprevention
3. Tyrosine kinase inhibition: An approach to drug development
4. Prostate cancer prevention: Investigational approaches and opportunities
5. Epidermal growth factor receptor tyrosine kinase inhibitors as potential cancer chemopreventives
6. c-erbB-2 oncogene expression in prostatic intraepithelial neoplasia: Mounting evidence for a precursor role
7. Expression of p160erbB3 and p185erbB2 in prostatic intraepithelial neoplasia and prostatic adenocarcinoma
8. Growth factors and their receptors as determinants in the proliferation and metastasis of human prostate cancer
9. Epidermal growth factor receptor monoclonal antibody inhibits constitutive receptor phosphorylation, reduces autonomous growth, and sensitizes androgen-independent prostatic carcinoma cells to tumor necrosis factor alpha
10. Anti-epidermal growth factor receptor monoclonal antibody 225 up-regulates p27KIP1 and induces G1 arrest in prostatic carcinoma cell line DU145
11. Some perspectives on dietary inhibition of carcinogenesis: Studies with curcumin and tea
12. Recent advances in chemoprevention of cancer
13. Natural antioxidants in chemoprevention
14. Cancer chemoprevention by polyhenolic compounds present in green tea
15. Soy intake and cancer risk: A review of the in vitro and in vivo data
16. A flavonoid antioxidant, silymarin, affords exceptionally high protection against tumor promotion in SENCAR mouse skin tumorigenesis model
17. Anti-carcinogenic effect of a flavonoid antioxidant silymarin in human breast cancer cells MDA-MB 468: Induction of G1 arrest through an increase in Cip1/p21 concomitant with a decrease in kinase activity of CDKs and associated cyclins
18. A flavonoid antioxidant silymarin inhibits activation of erbB1 signaling and induces cyclin dependent kinase inhibitors, G1 arrest, and anticarcinogenic effects in human prostate carcinoma DU145 cells
19. Silibinin decreases prostate-specific antigen with cell growth inhibition via G1 arrest, leading to differentiation of prostate carcinoma cells: Implications for prostate cancer intervention
20. Enhancement of chemosensitivity and programmed cell death by tyrosine kinase inhibitors correlates with EGFR expression in non-small cell lung cancer cells
21. Genistein exerts multiple suppressive effects on human breast carcinoma cells
22. Rationale for the use of genistein-containing soy matrices in chemoprevention trials for breast and prostate cancer
23. Effects of soybean isoflavones on cell growth and apoptosis of the human prostatic cancer cell line LNCaP
24. Genistein-induced upregulation of p21WAF1, downregulation of cyclin B, and induction of apoptosis in prostate cancer cells
25. Genistein, a component of soy, inhibits the expression of the EGF and ErbB2/Neu receptors in the rat dorsolateral prostate
26. Soy, disease prevention, and prostate cancer
27. Tea and cancer
28. Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols
29. Induction of apoptosis in prostate cancer cell lines by the green tea component, (-)-epigallocatechin-3 gallate
30. Suppression of extracellular signals and cell proliferation by the black tea polyphenol, theaflavin-3,3′-digallate
31. Cell cycle control in mammalian cells: Role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CDKIs)
32. Biomarkers of essential fatty acid consumption and risk of prostate carcinoma
33. Cancers of the prostate and breast among Japanese and white immigrants in Los Angeles County
34. Prostate cancer prevention: Risk reduction through life-style, diet, and chemoprevention
35. A mammalian scaffold complex that selectively mediates MAP kinase activation
36. Epidermal growth factor (EGF) receptor blockade inhibits the action of EGF, insulin-like growth factor I, and a protein kinase A activator on the mitogen-activated protein kinase pathway in prostate cancer cell lines
37. Activation of mitogen-activated protein kinase associated with prostate cancer progression
38. Relevance of cyclin D1 and other molecular markers to cancer chemoprevention