Tartary buckwheat flavonoid activates caspase 3 and induces HL-60 cell apoptosis

Methods and Findings in Experimental and Clinical Pharmacology

Volumn 23, Issue 8, 2001, Pages 427-432

  Ren, W ^a   Qiao, Z ^a   Wang, H ^a   Zhu, L ^a   Zhang, L ^a   Lu, Y ^a   Cui, Y ^a   Zhang, Z ^a   Wang, Z ^a  

^a SHANXI MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Caspase 3; Tartary buckwheat flavonoid

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANTINEOPLASTIC AGENT; CASPASE 3; DNA FRAGMENT; FLAVONOID; LIPOCORTIN 5;

ACUTE GRANULOCYTIC LEUKEMIA; ANGIOSPERM; APOPTOSIS; ARTICLE; ASSAY; CELL PROLIFERATION; CELL STRAIN HL 60; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DNA STRAND BREAKAGE; ENZYME ACTIVATION; FLOW CYTOMETRY; GEL ELECTROPHORESIS; GROWTH INHIBITION; HUMAN; HUMAN CELL; MICROSCOPY; SIGNAL TRANSDUCTION;

EID: 0035680495     PISSN: 03790355     EISSN: None     Source Type: Journal    
DOI: 10.1358/mf.2001.23.8.662129     Document Type: Article

References (30)

1. Effect of tea flavonoid supplementation on the susceptibility of low-density lipoprotein to oxidative modification
2. Genetic toxicology of dietary flavonoids
3. Citrus flavone tangeretin inhibits leukemic HL-60 cell growth partially through induction of apoptosis with less cytotoxicity on normal lymphocytes
4. Advances in research since 1986
5. Rapid colorimetric assay for cellular growth and survival: Application in proliferation and cytotoxicity assays
6. An improved calorimetric assay for interleukin 2
7. Intracellular infection by Leishmania donovani inhibits macrophage apoptosis
8. A novel assay for apoptosis. Flow cytametric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labeled Annexin V
9. Human ICE/CED-3 protease nomenclature
10. Proteolytic cleavage during chemotherapy-induced apoptosis
11. Protease activation during apoptosis: Death by a thousand cuts?
12. ICE Family proteases: Mediators of all apoptotic cell death?
13. A license to kill
14. ICE-related proteases in apoptosis
15. The role of the caspase family of cysteine proteases in apoptosis
16. Control of apoptosis by proteases
17. Cleavage of poly(ADP-ribose)polymerase by a proteinase with properties like ICE
18. Cleavage of lamin A by Mch2 but not CPP32: Multiple ICE-related proteases with distinct substrate recognition properties are active in apoptosis
19. ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis
20. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
21. Nuclear events of apoptosis in vitro in cell-free mitotic extracts: A model system for analysis of the active phase of apoptosis
22. Specific cleavage of the 70-kDa protein component of the UI small unclear ribonucleoprotein is a characteristic biochemical feature of apoptotic cell death
23. Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2
24. Caspase 2 and caspase 3 protein levels as predictors of survival in acute myelogenous leukemia
25. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
26. ICE family protease. Mediators of all apoptotic cell death
27. The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
28. Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
29. Contenders in Fas/TNF death signaling
30. Death receptors: Signaling and modulation