Targeting ICAM-1/LFA-1 interaction for controlling autoimmune diseases: Designing peptide and small molecule inhibitors

Peptides

Volumn 24, Issue 3, 2003, Pages 487-501

  Anderson, Meagan E ^a   Siahaan, Teruna J ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

Autoimmune diseases; Cell adhesion; ICAM 1; Immunological synapse; Immunotolerance; LFA 1; Peptides; T cell activation

Indexed keywords

4 ARYLTHIOS CINNAMIDE; ANTIBODY; BRIT 377; CYCLOPEPTIDE; G 497; INTERCELLULAR ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1 ANTIBODY; INTERCELLULAR ADHESION MOLECULE 1 MONOCLONAL ANTIBODY; INTERCELLULAR ADHESION MOLECULE 1 PEPTIDOMIMETIC; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1 ANTIBODY; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1 MONOCLONAL ANTIBODY; METHOTREXATE; MEVINOLIN; MONOCLONAL ANTIBODY B 7; PEPTIDE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANALYTIC METHOD; ANTIGEN EXPRESSION; ANTIGEN FUNCTION; ANTIGEN STRUCTURE; ANTINEOPLASTIC ACTIVITY; AUTOIMMUNE DISEASE; BINDING AFFINITY; CELL ADHESION; CLINICAL TRIAL; CYTOPLASM; DRUG BINDING; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG EFFICACY; DRUG FORMULATION; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; DRUG TARGETING; GRAFT REJECTION; HUMAN; IMMUNOLOGICAL TOLERANCE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE MIGRATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MODULATION; ORGAN TRANSPLANTATION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DOMAIN; REVIEW; SEQUENCE ANALYSIS; STRUCTURE ANALYSIS; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TARGET CELL; TARGET ORGAN; TH1 CELL; TH2 CELL;

EID: 0038404760     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(03)00083-4     Document Type: Review

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