In vitro adhesion and migration of T lymphocytes across monolayers of human brain microvessel endothelial cells: Regulation by ICAM-1, VCAM-1, E- selectin and PECAM-1

Journal of Neuropathology and Experimental Neurology

Volumn 58, Issue 2, 1999, Pages 138-152

  Wong, Donald ^a   Prameya, Rukmini ^a   Dorovini Zis, Katerina ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b VANCOUVER GENERAL HOSPITAL   (Canada)

Author keywords

Adhesion molecules; Brain; Endothelial cells; Human; Lymphocytes

Indexed keywords

CD31 ANTIGEN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; BLOOD BRAIN BARRIER; BRAIN BLOOD VESSEL; CONTROLLED STUDY; CYTOPLASM; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKOCYTE ADHERENCE; LYMPHOCYTE MIGRATION; MONOLAYER CULTURE; PRIORITY JOURNAL; PSEUDOPODIUM; T LYMPHOCYTE; VASCULAR ENDOTHELIUM;

EID: 0033030208     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005072-199902000-00004     Document Type: Article

References (56)

1. Devine L, Lightman S, Greenwood J. Lymphocyte migration across the anterior and posterior blood-retinal barrier in vitro. Cell Immunol 1996; 168:267-75
2. Ohmori K, Takada A, Ohwaki I et al. A distinct type of sialyl Lewis X antigen defined by a novel monoclonal antibody is selectively expressed on helper memory T cells. Blood 1993:82:2797-2805
3. Shimizu Y, Newman W, Gopal TV et al. Four molecular pathways of T cell adhesion to endothelial cells: Roles of LFA-1, VCAM-1 and ELAM-1 and changes in pathway hierarchy under different activation conditions. J Cell Biol 1991;113:1203-12
4. Silber A, Newman W, Reimann KA, Hendricks E, Walsh D, Ringler DJ. Kinetic expression of endothelial adhesion molecules and relationship to leukocyte recruitment in two cutaneous models of inflammation. Lab Invest 1994;70:163-75
5. Wysocki J, Issekutz TB. Effect of T cell activation on lymphocyte-endothelial cell adherence and the role of VLA-4 in the rat. Cell Immunol 1992;140:420-31
6. Oppenheimer-Marks N, Davis LS, Bogue DT, Ramberg J, Lipsky PE. Differential utilization of ICAM-1 and VCAM-1 during the adhesion and transendothelial migration of human T lymphocytes. J Immunol 1991;147:2913-21
7. Barten DM, Ruddle NH. Vascular cell adhesion molecule-1 modulation by tumor necrosis factor in experimental allergic encephalomyelitis. J Neuroimmunol 1994;51:123-33
8. Cannella B, Cross AH, Raine CS. Upregulation and coexpression of adhesion molecules correlate with relapsing autoimmune demyelination in the central nervous system. J Exp Med 1990;172: 1521-24
9. Cannella B, Cross AH, Raine CS. Adhesion-related molecules in the central nervous system. Up-regulation correlates with inflammatory cell influx during relapsing experimental autoimmune encephalomyelitis. Lab Invest 1991;65:23-31
10. Dopp JM, Breneman, SM, Olschowka JA. Expression of ICAM-1, VCAM-1, L-selectin and leukosialin in the mouse central nervous system during the induction and remission stages of experimental allergic encephalomyelitis. J Neruoimmunol 1994;54:129-44
11. Okada Y, Copeland BR, Mori E, Tung M-M, Thomas WS, del Zoppo GJ. P-selectin and intercellular adhesion molecule-1 expression after focal brain ischemia and reperfusion. Stroke 1994;25: 202-11
12. Raine CS, Cannella B, Duijvestijn AM, Cross AH. Homing to central nervous system vasculature by antigen-specific lymphocytes. II. Lymphocyte/endothelial cell adhesion during the initial stages of autoimmune demyelination. Lab Invest 1990;63:476-89
13. Raine CS, Lee SC, Scheinberg LC, Duijvestijn AM, Cross AH. Adhesion molecules on endothelial cells in the central nervous system: An emerging area in the neuroimmunology of multiple sclerosis. Clin Immunol Immunopathol 1990;57:173-87
14. Steffen BJ, Butcher EC, Engelhardt B. Evidence for involvement of ICAM-1 and VCAM-1 in lymphocyte interactions with endothelium in experimental autoimmune encephalomyelitis in the central nervous system in the SJL/J mouse. Am J Path 1994;145:189-201
15. Verbeek MM, Westphal JR, Ruiter DJ, deWaal RMW. T lymphocyte adhesion to human brain pericytes is mediated via very late antigen-4/vascular cell adhesion molecule-1 interactions. J Immunol 1995;154:5876-84
16. Wang X, Siren A-L, Liu Y, Yue T-L, Barone FC, Feuerstein GZ. Upregulation of intercellular adhesion molecule 1 (ICAM-1) on brain microvascular endothelial cells in rat ischemic cortex. Molec Brain Res 1994;26:61-68
17. Cannella B, Raine CS. The adhesion molecule and cytokine profile of multiple sclerosis lesions. Ann Neurol 1995;37:424-35
18. Sobel RA, Mitchell ME, Fondren G. Intercellular adhesion molecule-1 (ICAM-1) in cellular immune reactions in the human central nervous system. Am J Path 1990;136:1309-16
19. Vora AJ, Perry ME, Hobbs C, Dumonde DC, Brown KA. Selective binding of peripheral blood lymphocytes to the walls of cerebral vessels in frozen sections of human brain. J Immunol Meth 1995; 180:165-80
20. Turner GD, Morrison H, Jones M et al. An immunohistochemical study of the pathology of fetal malaria. Evidence for widespread endothelial activation and a potential role for intercellular adhesion molecule-1 in cerebral sequestration. Am J Pathol 1994;145:1057-69
21. Xiao L, Yang C, Dorovini-Zis K et al. Plasmodium falciparum: Involvement of additional receptors in the cytoadherence of infected erythrocytes to microvascular endothelial cells. Exp Parasit 1996;84:42-55
22. Wong D, Dorovini-Zis K. Upregulation of intercellular adhesion molecule-1 (ICAM-1) expression in primary cultures of human brain microvessel endothelial cells by cytokines and lipopolysaccharide. J Neuroimmunol 1992;39:11-21
23. Wong D, Dorovini-Zis K. Expression of vascular cell adhesion molecule-1 (VCAM-1) by human brain microvessel endothelial cells in primary culture. Microvasc Res 1995;49:325-39
24. Wong D, Dorovini-Zis K. Regulation by cytokines and lipopolysaccharide of E-selectin expression by human brain microvessel endothelial cells in primary culture. J Neuropath Exp Neurol 1996; 55:225-35
25. Wong D, Dorovini-Zis K. Platelet/endothelial cell adhesion molecule-1 (PECAM-1) expression by human brain microvessel endothelial cells in primary culture. Brain Res 1996;731:217-20
26. Dorovini-Zis K, Prameya R, Bowman PD. Culture and characterisation of microvascular endothelial cells derived from human brain. Lab Invest 1991;64:425-36
27. Dorovini-Zis K, Bowman PD, Prameya R. Adhesion and migration of human polymorphonuclear leukocytes across cultured bovine brain microvessel endothelial cells. J Neuropath Exp Neurol 1992; 51:194-205
28. Berman ME, Muller WA. Ligation of platelet/endothelial cell adhesion molecule 1 (PECAM-1/CD31) on monocytes and neutrophils increase binding capacity of leukocyte CR3 (CD11b/CD18). J Immunol 1995;154:299-307
29. Leavesley DI, Oliver JM, Swart BW, Berndt MC, Haylock DN, Simmons PJ. Signals from platelet/endothelial cell adhesion molecule enhance the adhesive activity of the very late antigen-4 integrin of human CD34+ hemopoietic progenitor cells. J Immunol 1994;153:4673-83
30. Piali L, Albelda SM, Baldwin HS, Hammel P, Gisler RH, Imhof BA. Murine platelet endothelial cell adhesion molecule (PECAM-1)/CD31 modulates β2 integrins on lymphokine-activated killer cells. Eur J Immunol 1993;23:2464-71
31. Tanaka Y, Albelda SM, Horgan KJ et al. CD31 expressed on distinctive T cell subsets is a preferential amplifier of β1 integrinmediated adhesion. J Exp Med 1992;176:245-53
32. Bereta J, Bereta M, Cohen S, Cohen MC. Regulation of VCAM-1 expression and involvement in cell adhesion to murine microvascular endothelium. Cell Immunol 1993;147:313-30
33. deVries HE, Moor ACE, Blom-Roosemalen MCM et al. Lymphocyte adhesion to brain capillary endothelial cells in vitro. J Neuroimunol 1994;52:1-8
34. Male D, Rahman J, Pryce G, Tamatani T, Miyasaka M. Lymphocyte migration into the CNS modelled in vitro: Roles of LFA-1, ICAM-1 and VLA-4. Immunology 1994;81:366-72
35. Matsuda M, Tsukada N, Miyagi K, Yanagisawa N. Adhesion of lymphocytes to endothelial cells in experimental allergic encephalomyelitis before and after treatment with endotoxin lipopolysaccharide. Int Arch Allergy Immunol 1995;106:335-44
36. Waldschmidt MM, Fabry Z, Keiner J, Love-Homan L, Hart MN. Adhesion of splenocytes to brain microvascular endothelium in the BALB/c and SJL/j mouse systems. J Neuroimmunol 1991;35:191-200
37. Engelhardt B, Conley FK, Butcher EC. Cell adhesion molecules on vessels during inflammation in the mouse central nervous system. J Neuroimmunol 1994;51:199-208
38. O'Neill JK, Butter C, Baker D et al. Expression of vascular addressins and ICAM-1 by endothelial cells in the spinal cord during chronic relapsing experimental allergic encephalomyclitis in the Biozzi AB/H mouse. Immunology 1991;72:520-25
39. Wilcox CE, Ward AM, Evans A, Baker D, Rothlein R, Turk JL. Endothelial cell expression of the intercellular adhesion molecule-1 (ICAM-1) in the central nervous system of guinea pigs during acute and chronic relapsing experimental allergic encephalomyelitis. J Neuroimmunol 1990;30:43-51
40. Yednock TA, Cannon C, Fritz LC, Sanchez-Madrid F, Steinman L, Karin N. Prevention of experimental autoimmune encephalomyelitis by antibodies against α4β1 integrin. Nature 1992;356:63-66
41. Rieckmann P, Michel U, Albrecht M, Bruck W, Wockel L, Felgenhauer K. Soluble forms of intercellular adhesion molecule-1 (ICAM-1) block lymphocyte attachment to cerebral endothelial cells. J Neuroimmunol 1995;60:9-15
42. Bird IN, Spragg JH, Ager A, Matthews N. Studies of lymphocyte transendothelial migration: Analysis of migrated cell phenotypes with regard to CD31 (PECAM-1), CD45RA and CD45RO. Immunol 1993;80:553-60
43. Muller WA, Weigl SA, Deng X, Phillips DM. PECAM-1 is required for transendothelial migration of leukocytes. J Exp Med 1993;178: 449-60
44. Masuyama J, Berman JS, Cruikshank WW, Morimoto C, Center DM. Evidence for recent as well as long term activation of T cells migrating through endothelial cell monolayers in vitro. J Immunol 1992;48:1367-74
45. Rohnelt RK, Hoch G, Reiss Y, Engelhardt B. Immunosurveillance modelled in vitro - naive and memory T cells spontaneously migrate across unstimulated microvascular endothelium. Int Immunol 1997;9:435-50
46. Diacovo TG, Roth SJ, Morita CT, Rosat J-P, Brenner MB, Springer TA. Interactions of human α/β and γ/δ T lymphocyte subsets in shear flow with E-selectin and P-selectin. J Exp Med 1996;183: 1193-1203
47. Wong DCK. Endothelial cell adhesion molecules: Expression, upregulation and modulation of human brain microvessel endothelial cell-leukocyte interactions. Ph.D. thesis. Vancouver, Canada, The University of British Columbia. 1995.
48. Greenwood J, Howes R, Lightman S. The blood-retinal barrier in experimental autoimmune uveoretinitis. Leukocyte interactions and functional damage. Lab Invest 1994;70:39-52
49. Issazadeh S, Ljungdahl Å, Höjeberg B, Mustafa H, Olsson T. Cytokine production in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis: Dynamics of mRNA expression for interleukin-10, interleukin-12, cytolysin, tumor necrosis factor α and tumor necrosis factor β. J Neuroimmunol 1995; 61:205-12
50. Rieckmann P, Albrecht M, Kitze B et al. Tumor necrosis factor-α messenger RNA expression in patients with relapsing-remitting multiple sclerosis is associated with disease activity. Ann Neurol 1995;37:82-88
51. 14C-labeled cells during acute, chronic and relapsing experimental allergic encephalomyelitis. Lab Invest 1990;63:162-70
52. Trotter J, Steinman L. Homing of Lyt-2+ and Lyt-2-T cell subsets and B lymphocytes to the central nervous system of mice with acute experimental allergic encephalomyelitis. J Immunol 1984; 132:2919-23
53. Werdelin O, McCluskey RT. The nature and the specificity of mononuclear cells in experimental autoimmune inflammations and the mechanisms leading to their accumulation. J Exp Med 1971; 133:1242-63
54. Lou J, Dayer JM, Grau GE, Burger D. Direct cell/cell contact with stimulated T lymphocytes induces the expression of cell adhesion molecules and cytokines by human brain microvascular endothelial cells. Eur J Immunol 1996;26:3107-13
55. Huynh HK, Dorovini-Zis K. Effects of interferon-γ on primary cultures of human brain microvessel endothelial cells. Am J Path 1993; 142:1265-78
56. Traugott U, Raine CS. Multiple sclerosis. Evidence for antigen presentation in situ by endothelial cells and astrocytes. J Neurol Sci 1985;69:365-70