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We regret that space limitations have precluded reference to many (most) important publications, as well as discussion of important contributions from studies of other leukocytes. We thank our present and prior laboratory members for their contributions to the ideas put forward here, C Mackay, U von Andnan, and L. Glickstein for critical review, and C Goodnow for extensive discussions and input Supported in part by NIH grants and by an award from the Department of Veterans Affairs.
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