Tumor necrosis factor (TNF)-α and interleukin (IL)-1β down-regulate intercellular adhesion molecule (ICAM)-2 expression on the endothelium

Cell Adhesion and Communication

Volumn 6, Issue 5, 1998, Pages 381-400

  Mclaughlin, Fiona ^a   Hayes, Brian P ^a   Horgan, Carmel M T ^a   Beesley, Julian E ^a   Campbell, Callum J ^a   Randi, Anna M ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Cell adhesion molecules; Endothelium; Gene expression; Human; Intercellular junctions; Vascular

Indexed keywords

GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 2; INTERLEUKIN 1BETA; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL JUNCTION; CONTROLLED STUDY; DNA TRANSFECTION; GENE REPRESSION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REPORTER GENE; TRANSCRIPTION REGULATION; VASCULAR ENDOTHELIUM;

EID: 0032427010     PISSN: 10615385     EISSN: None     Source Type: Journal    
DOI: 10.3109/15419069809109147     Document Type: Article

References (55)

1. Acheson, A. et al. (1997) "NCAM polysialic acid can regulate both cell-cell and cell-substrate interactions". Journal of Cell Biology 114(1), 143-153.
2. Almenar-Queralt, Angels et al. (1995) "Apical topography and modulation of ICAM-1 expression on activated endothelium". American Journal of Pathology 147(5), 1278-1287.
3. Ardman, B. et al. (1992) "CD43 interferes with T-lymphocyte adhesion". Proceedings of the National Academy of Sciences of the United States of America 89, 5001.
4. Bradley, J.R. et al. (1995) "Hydrogen peroxide-induced endothelial retraction is accompanied by a loss of the normal spatial organisation of endothelial cell adhesion molecules". American Journal of Pathology 147, 627-641.
5. Buckley, C.D. and Simmons, D.L. (1997) "Cell adhesion: a new target for therapy". Molecular Medicine Today 3, 449-456.
6. Campanero, M.R. et al. (1993) "ICAM-3 interacts with LFA-1 and regulates the LFA-1/ICAM-1 cell adhesion pathway". Journal of Cell Biology 123(4), 1007-1016.
7. Campanero, M.R. et al. (1994) "ICAM-3 regulates lymphocyte morphology and integrin-mediated T cell interaction with endothelial cell and extracellular matrix ligands". Journal of Cell Biology 127(3), 867-878.
8. Casasnovas, J.M. et al. (1997) "Crystal structure of ICAM-2 reveals a distinctive integrin recognition surface". Nature 387(6630), 312-315.
9. Collins, T. et al. (1995) "Transcriptional regulation of endothelial cell adhesion molecules: NF-kB and cytokine-inducible enhancers". FASEB J 9(10), 899-909.
10. Conway, E.M. and Rosenberg, R.D. (1988) "Tumor Necrosis Factor suppresses transcription of the thrombomodulin gene in endothelial cells". Molecular and Cellular Biology 8(12), 5588-5592.
11. Cowan, P.J. et al. (1996) "Targeting gene expression to endothelial cells in transgenic mice using the human intercellular adhesion molecule 2 promoter". Transplantation 62(2), 155-160.
12. 1 Integrin (laminin receptor) is down-regulated by Tumor Necrosis Factor α and Interleukin-1β in human endothelial cells". Journal of Biological Chemistry 267(26), 18 303-18 307.
13. 3) in human endothelial cells". Journal of Biological Chemistry 266, 7638-7645.
14. Defougerolles, A.R. et al. (1991) "Characterisation of ICAM-2 and evidence for a third counter-receptor for LFA-1". Journal of Experimental Medicine 174, 253-267.
15. Delia, D. et al. (1993) "CD34 expression is regulated reciprocally with adhesion molecules in vascular endothelial cells in vitro". Blood 81(4), 1001-1008.
16. Eisenberg, S.P. et al. (1990) "Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist". Nature 343, 341-346.
17. Esmon, C.T. (1995) "Thrombomodulin as a model of molecular mechanisms that modulate protease specificity and function at the vessel surface". FASEB J 9, 946-955.
18. Espel, E. et al. (1990) "Activity and Interteukin 1 responsiveness of SV40 enhancer motifs in a rodent immature T cell line". EMBO J 9(3), 929-937.
19. Fawcett, J. et al. (1992) "Molecular cloning of ICAM-3, a third ligand for LFA-1, constitutively expressed on resting leukocytes". Nature 360, 481-484.
20. Gahmberg, C.G. et al. (1991) "The human leukocyte-adhesion ligand, Intercellular-Adhesion Molecule 2". European Journal of Biochemistry 195, 177-182.
21. Granger, D.N. and Kubes, P. (1994) "The microcirculation and inflammation: modulation of leukocyte-endothelial cell adhesion". Journal of Leukocyte Biology 55, 662-674.
22. Griffioen, A.W. et al. (1996) "Endothelial intercellular adhesion molecule-1 expression is suppressed in human malignancies - the role of angiogenic factors". Cancer Research 56(5), 1111-1117.
23. Hooper, W.C. et al. (1994) "Tumor Necrosis Factor-α down-regulates Protein S secretion in human microvascular and umbilical cells but not in the HepG-2 hepatoma cell line". Blood 84(2), 483-489.
24. Hou, J. et al. (1994) "Regulatory elements and transcription factors controlling basal and cytokine induced expression of the gene encoding ICAM-1". Proceedings of the National Academy of Sciences of the United Slates of America 91, 11641-11645.
25. Hynes, R.O. (1992) "Integrins: Versatility, modulation, and signaling in cell adhesion". Cell 69, 11-25.
26. Jones, D.A. et al. (1994) "A two-step adhesion cascade for T cell/ endothelial cell interactions under flow conditions". Journal of Clinical Investigations 94, 2443-2450.
27. Kuno, K. and Matsushima, K. (1994) "The IL-1 receptor signalling pathway". Journal of Leukocyte Biology 56, 542-547.
28. Li, R. et al. (1993a) "A leukocyte integrin binding peptide from intercellular adhesion molecule-2 stimulated T cell adhesion and natural killer cell activity". Journal of Biological Chemistry 268, 21 474-21 477.
29. Li, R. et al. (1993b) "A peptide from ICAM-2 binds to the leukocyte integrin CD11a/CD18 and inhibits endothelial cell adhesion". Journal of Biological Chemistry 268(23), 17 513-17 518.
30. Li, R. et al. (1995) "A peptide derived from the intercellular adhesion molecule-2 regulates the avidity of the leukocyte integrins CD11b/CD18 and CD11c/CD18". Journal of Cell Biology 129(4), 1143-1153.
31. Menger, M.D. and Vollmar, B. (1996) "Adhesion molecules as determinants of disease: from molecular biology to surgical research". British Journal of Surgery 83, 588-601.
32. Muller, W.A. et al. (1993) "PECAM-1 is required for transendothelial migration of leukocytes". Journal of Experimental Medicine 178, 449-460.
33. Newman, P.J. (1997) "Cell adhesion in vascular biology, the biology of PECAM-1". Journal of Clinical Investigation 99(1), 3-8.
34. Nortamo, P. et al. (1991) "The expression of human intercellular adhesion molecule-2 is refractory to inflammatory cytokines". European Journal of Immunology 21, 2629-2632.
35. Patterson, C. et al. (1996) "Down-regulation of vascular endothelial growth factor receptors by Tumor Necrosis Factor a in cultured human vascular endothelial cells". Journal of Clinical Investigation 98(2), 490-496.
36. Pober, J.S. and Cotran, R.S. (1990) "Cytokines and endothelial cell biology". Physiological Reviews 70, 427-451.
37. Puri, K.D. et al. (1995) "Sialomucin CD34 is the major L-selectin ligand in human tonsil high endothetial venules". Journal of Cell Biology 131(1), 261-270.
38. Rezaoe, P. et al. (1997) "Expression of adhesion molecules on human fetal cerebral vessels: relationship to microglial colonisation during development". Developmental Brain Research 104, 175-189.
39. Romer, L.H. et al. (1995) "IFN-γ and TNF-α induce redistribution of PECAM-1 (CD31) on human endothelial cells". Journal of Immunology 154, 6582-6592.
40. Ross, R. (1997) "The pathogenesis of atherosclerosis: a perspective for the 1990s". Nature 362, 801-809.
41. Roth, S.J. et al. (1995) "Characterization of transendothelial chemotaxis of T lymphocytes". Journal of Immunological Methods 188(1), 97-116.
42. Sambrook, J., Fritsch, E.F. and Maniatis, T. Molecular Cloning, a laboratory manual (2nd edition), 1989.
43. Schindler, U. and Baichwal, V.R. (1994) "Three NF-κB binding sites in the human E selectin gene required for maximal Tumor Necrosis Factor α-induced expression". Molecular and Cellular Biology 14, 5820-5831.
44. Schleiffenbaum, B. and Fehr, J. (1996) "Regulation and selectivity of leukocyte emigration". Journal of Lab. Clin. Med. 127, 151-168.
45. Skubitz, K.M. et al. (1997) "CD50 monoclonal antibodies inhibit neutrophil activation". Journal of Clinical Investigation 159, 820-828.
46. Somersalo, K. et al. (1995) "Activation of natural killer cell migration by leukocyte integrin-binding peptide from Intracellular Adhesion Molecule 2 (ICAM-2)". Journal of Biological Chemistry 270(15), 8629-8636.
47. Springer, T.A. (1994) "Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm". Cell 76, 301-314.
48. Staunton, D.E. et al. (1989) "Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1". Nature 339, 61-64.
49. Stewart, R.J. et al. (1996) "Vascular endothelial platelet endothelial cell adhesion molecule-1 (PECAM-1) expression is decreased by TNF-α and IFN-γ". Journal of Immunology 156, 1221-1228.
50. Su, S. et al. (1997) "High-throughput RT-PCR analysis of multiple transcripts using a microplate RNA isolation procedure". BioTechniques 22(6), 1107-1313.
51. Vandenabeele, P. et al. (1995) "Two tumor necrosis factor receptors: structure and function". Trends In Cell Biology 5, 392-399.
52. Vazeux, R. et al. (1992) "Cloning and characterisation of a new intercellular adhesion molecule ICAM-R". Nature 360, 485-488.
53. von der Ahe, D. et al. (1993) "Ets transcription factor binding site is required for positive and TNFα-induced negative promoter regulation". Nucleic Acids Research 21(24), 5636-5634.
54. Xie, J.L. et al. (1995) "Intercellular Adhesion Molecule-2 (CD102) binds to the leukocyte integrin CD11b/CD18 through the A domain". Journal of Immunology 155(7). 3619-3628.
55. Zocchi, M.R. et al. (1996) "CD31/PECAM-1 driven chemokine-independent transmigration of human T lymphocytes". European Journal of Immunology 26, 759-767.