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Volumn 277, Issue 12, 2002, Pages 10590-10598
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Small molecule inhibitors induce conformational changes in the I domain and the I-like domain of lymphocyte function-associated antigen-1. Molecular insights into integrin inhibition
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Author keywords
[No Author keywords available]
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Indexed keywords
ADHESION;
ANTIBODIES;
CELLS;
CLONING;
DISEASES;
MOLECULE INHIBITORS;
BIOCHEMISTRY;
BETA2 INTEGRIN;
CD11B ANTIGEN;
INTERCELLULAR ADHESION MOLECULE 1;
INTERCELLULAR ADHESION MOLECULE 2;
INTERCELLULAR ADHESION MOLECULE 3;
LFA 451;
LFA 703;
LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1;
MEVINOLIN;
MONOCLONAL ANTIBODY;
PRAVASTATIN;
PROTEIN INHIBITOR;
UNCLASSIFIED DRUG;
XVA 143;
ANTIGEN ANTIBODY REACTION;
ANTIGEN BINDING;
ARTICLE;
BINDING SITE;
CELL SURFACE;
CONFORMATIONAL TRANSITION;
CONTROLLED STUDY;
HUMAN;
HUMAN CELL;
LEUKOCYTE;
LEUKOCYTE ADHERENCE;
LIGAND BINDING;
PRIORITY JOURNAL;
PROTEIN CONFORMATION;
PROTEIN DOMAIN;
PROTEIN EXPRESSION;
SIGNAL TRANSDUCTION;
ALLOSTERIC SITE;
BINDING SITES;
BIOTINYLATION;
CELL ADHESION;
CELL LINE;
DOSE-RESPONSE RELATIONSHIP, DRUG;
EDETIC ACID;
ENZYME-LINKED IMMUNOSORBENT ASSAY;
EPITOPES;
FLOW CYTOMETRY;
HUMANS;
INHIBITORY CONCENTRATION 50;
INTEGRINS;
INTERCELLULAR ADHESION MOLECULE-1;
JURKAT CELLS;
LEUKOCYTES;
LIGANDS;
LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1;
MACROPHAGE-1 ANTIGEN;
MODELS, BIOLOGICAL;
MODELS, CHEMICAL;
MODELS, MOLECULAR;
PROTEIN BINDING;
PROTEIN CONFORMATION;
PROTEIN STRUCTURE, TERTIARY;
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EID: 0037155873
PISSN: 00219258
EISSN: None
Source Type: Journal
DOI: 10.1074/jbc.M110521200 Document Type: Article |
Times cited : (78)
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References (32)
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