Differential presentation of the same MHC class I epitopes by fibroblasts and dendritic cells

Journal of Immunology

Volumn 160, Issue 5, 1998, Pages 2139-2144

  Butz, Eric A ^a   Bevan, Michael J ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; EPITOPE; GLYCOPROTEIN; NUCLEOPROTEIN; VIRUS PROTEIN;

ANTIGEN PRESENTATION; ARTICLE; DENDRITIC CELL; FIBROBLAST; HUMAN CELL; IMMUNE RESPONSE; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; QUANTITATIVE DIAGNOSIS;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, VIRAL; CELL LINE; CYSTEINE ENDOPEPTIDASES; CYTOTOXICITY, IMMUNOLOGIC; DENDRITIC CELLS; EPITOPES; FEMALE; FIBROBLASTS; FIBROSARCOMA; GLYCOPROTEINS; HISTOCOMPATIBILITY ANTIGENS CLASS I; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PEPTIDE FRAGMENTS; PROTEINS; T-LYMPHOCYTES, CYTOTOXIC; TUMOR CELLS, CULTURED; VIRAL PROTEINS;

EID: 0032030661     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Germain, R. N. 1994. MHC-dependent antigen processing and peptide presentation providing ligands for T lymphocyte activation. Cell 76:287.
2. Heemels, M. T., and H. Ploegh. 1995. Generation, translocation, and presentation of MHC class I-restricted peptides. Annu. Rev. Biochem. 64:463.
3. Jondal, M., R. Schirmbeck, and J. Reimann. 1996. MHC class I-restricted CTL responses to exogenous antigens. Immunity 5:295.
4. Hill, A., and H. Ploegh. 1995. Getting the inside out: the transporter associated with antigen processing (TAP) and the presentation of viral antigen. Proc. Natl. Acad. Sci. USA 92:341.
5. Johnson, J. G., and M. K. Jenkins. 1993. Accessory cell-derived signals required for T cell activation. Immunol. Res. 12:48.
6. Huang, A. Y., P. Golumbek, M. Ahmadzadeh, E. Jaftee, D. Pardoll, and H. Levitsky. 1994. Bone marrow-derived cells present MHC class I-restricted tumour antigens in priming of antitumour immune responses. Ciba Found. Symp. 187-229.
7. Doe, B., M. Selby, S. Barnett, J. Baenziger, and C. M. Walker. 1996. Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells. Proc. Natl. Acad. Sci. USA 93:8578.
8. Corr, M. D. J. Lee, D. A. Carson, and H. Tighe. 1996. Gene vaccination with naked plasmid DNA: mechanism of CTL priming. J. Exp. Med. 184:1555.
9. Brossart, P., A. W. Goldrath, E. A. Butz, S. Martin, and M. J. Bevan. 1997. Virus-mediated delivery of antigenic epitopes into dendritic cells as a means to induce CTL. J. Immunol. 158:3270.
10. Bohm, W., R. Schirmbeck, A. Elbe, K. Melber, D. Diminky, G. Kraal, N. van Rooijen, Y. Barenholz, and J. Reimann. 1995. Exogenous hepatitis B surface antigen particles processed by dendritic cells or macrophages prime murine MHC class I-restricted cytotoxic T lymphocytes in vivo. J. Immunol. 155:3313.
11. Nair, S., J. S. Babu, R. G. Dunham, P. Kanda, R. L. Burke, and B. T. Rouse. 1993. Induction of primary, antiviral cytotoxic, and proliferative responses with antigens administered via dendritic cells. J. Virol. 67:4062.
12. Nair, S., A. M. Buiting, R. J. Rouse, R. N. Van, L. Huang, and B. T. Rouse. 1995. Role of macrophages and dendritic cells in primary cytotoxic T lymphocyte responses. Int. Immunol. 7:679.
13. Southern, P. J., M. K. Singh, Y. Riviere, D. R. Jacoby, M. J. Buchmeier, and M. B. A. Oldstone. 1987. Molecular characterization of the genomic S RNA segment from lymphocytic choriomeningitis virus. Virology 157:145.
14. Buchmeier, M. J., and M. B. Oldstone. 1979. Protein structure of lymphocytic choriomeningitis virus: evidence for a cell-associated precursor of the virion glycopeptides. Virology 99:111.
15. Gairin, J. E., H. Mazarguil, D. Hudrisier, and M. B. Oldstone. 1995. Optimal lymphocytic choriomeningitis virus sequences restricted by H-2Db major histocompatibility complex class 1 molecules and presented to cytotoxic T lymphocytes. J. Virol. 69:2297.
16. Van Kaer, L., R. P. G. Ashton, M. Eichelberger, M. Gaczynska, K. Nagashima, K. L. Rock, A. L. Goldberg, P. C. Doherty, and S. Tonegawa. 1994. Altered peptidase and viral-specific T cell response in LMP2 mutant mice. Immunity 1:533.
17. Ahmed, R., A. Salmi, L. D. Butler, J. M. Chiller, and M. B. A. Oldstone. 1984. Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice: role in suppression of cytotoxic T lymphocyte response and viral persistence. J. Exp. Med. 160:521.
18. Hosaka, Y., Y. Yasuda, O. Seriburi, M. G. Moran, and K. Fukai. 1986. In vitro secondary generation of cytoioxic T lymphocytes in mice with mumps virus and their mumps-specific cytotoxicity among paramyxoviruses. J. Virol. 57:1113.
19. + T cells using an ELISPOT assay. J. Immunol. Methods 181:45.
20. Chen, W., S. Khilko, J. Fecondo, D. H. Margulies, and J. McCluskey. 1994. Determinant selection of major histocompatibility complex class I-restricted antigenic peptides is explained by class I-peptide affinity and is strongly influenced by nondominant anchor residues. J. Exp. Med. 180:1471.
21. Schumacher, T. N., M. T. Heemels, J. J. Neefjes, W. M. Kast, C. J. Melief, and H. L. Ploegh. 1990. Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro. Cell 62:563.
22. Deng, Y., J. W. Yewdell, L. C. Eisenlohr, and J. R. Bennink. 1997. MHC affinity, peptide liberation, T cell repertoire and immunodominance all contribute to the paucity of MHC class I-restricted peptides recognized by antiviral CTL. J. Immunol. 158:1507.
23. Sette, A., A. Vitiello, B. Reherman, P. Fowler, R. Nayersina, W. M. Kast, C. J. Melief, C. Oseroff, L. Yuan, J. Ruppert, J. Sidney, M.-F. del Guercio, et al. 1994. The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes. J. Immunol. 153:5586.
24. van der Burg, S. H., M. J. Visseren, R. M. Brandt, W. M. Kast, and C. J. Melief. 1996. Immunogenicity of peptides bound to MHC class I molecules depends on the MHC-peptide complex stability. J. Immunol. 156:3308.
25. Buchmeier, M. J., P. J. Southern, B. S. Parekh, M. K. Wooddell, and M. B. A. Oldstone. 1987. Site-specific antibodies define a cleavage site conserved among arenavirus GP-C glycoproteins. J. Virol. 61:982.
26. Sijts, A. J., M. S. Villanueva, and E. G. Pamer. 1996. CTL epitope generation is tightly linked to cellular proteolysis of a Listeria monocytogenes antigen. J. Immunol. 156:1497.
27. Sijts, A. J., A. Neisig, J. Neefjes, and E. G. Pamer. 1996. Two Listeria monocytogenes CTL epitopes are processed from the same antigen with different efficiencies. J. Immunol. 156:683.
28. Anton, L. C., J. W. Yewdell, and J. R. Bennink. 1997. MHC class I-associated peptides produced from endogenous gene products with vastly different efficiencies. J. Immunol. 158:2535.
29. Kageyama, S., T. J. Tsomides, Y. Sykulev, and H. N. Eisen. 1995. Variations in the number of peptide-MHC class I complexes required to activate cytotoxic T cell responses. J. Immunol. 154:567.
30. Sykulev, Y., M. Joo, I. Vturina, T. J. Tsomides, and H. N. Eisen. 1996. Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response. Immunity 4:565.
31. Valitutti, S., S. Muller, M. Dessing, and A. Lanzavecchia. 1996. Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy. J. Exp. Med. 183:1917.
32. Oldstone, M. B., H. Lewicki, P. Borrow, D. Hudrisier, and J. E. Gairin. 1995. Discriminated selection among viral peptides with the appropriate anchor residues: implications for the size of the cytotoxic T-lymphocyte repertoire and control of viral infection. J. Virol. 69:7423.
33. + CTL response to an influenza hemagglutinin epitope reflects limited T cell availability. J. Immunol. 157:505.
34. van der Most, R. G., A. Sette, C. Oseroff, J. Alexander, K. K. Murali, L. L. Lau, S. Southwood, J. Sidney, R. W. Chesnut, M. Matloubian, and R. Ahmed. 1996. Analysis of cytotoxic T cell responses to dominant and subdominant epitopes during acute and chronic lymphocytic choriomeningitis virus infection. J. Immunol. 157:5543.
35. Stohlman, S., C. Bergmann, N. LaMonica, M. Lai, J. Yeh, and S. Kyuwa. 1993. JHM virus-specific cytotoxic T cells derived from the central nervous system. Adv. Exp. Med. Biol. 342:419.
36. Stohlman, S. A., S. Kyuwa, J. M. Polo, D. Brady, M. M. Lai, and C. C. Bergmann. 1993. Characterization of mouse hepatitis virus-specific cytotoxic T cells derived from the central nervous system of mice infected with the JHM strain. J. Virol. 67:7050.
37. Stohlman, S. A., C. C. Bergmann, R. C. van der Veen, and D. R. Hinton. 1995. Mouse hepatitis virus-specific cytotoxic T lymphocytes protect from lethal infection without eliminating virus from the central nervous system. J. Virol. 69: 684.