Increased CD95/Fas-induced apoptosis of HIV-specific CD8+ T cells

Immunity

Volumn 15, Issue 6, 2001, Pages 871-882

  Mueller, Yvonne M ^a   De Rosa, Stephen C ^c   Hutton, Justin A ^a   Witek, James ^b   Roederer, Mario ^c   Altman, John D ^d   Katsikis, Peter D ^a  

^a Department of Microbiology and Immunology ^*  (United States)

^b DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CD45 ANTIGEN; CD8 ANTIGEN; DIPEPTIDYL PEPTIDASE IV; FAS ANTIGEN; LIPOCORTIN 5;

ADOLESCENT; ADULT; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL SPECIFICITY; CELL SURVIVAL; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOMEGALOVIRUS; CYTOTOXICITY; EFFECTOR CELL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MEMORY CELL; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0035695913     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(01)00246-1     Document Type: Article

References (47)

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2. (+) T cells produce antiviral cytokines but are impaired in cytolytic function
3. - human T cells
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5. Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis
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13. + cell subset in HIV disease implicate replicative senescence in HIV pathogenesis
14. + T cells from human immunodeficiency virus- infected persons
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21. + T cells
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25. Human monocytic cells contain high levels of intracellular Fas ligand: Rapid release following cellular activation
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29. + T cells are required to sustain CD8+ cytotoxic T cell responses during chronic viral infection
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33. Accumulation of human immunodeficiency virus-specific cytotoxic T lymphocytes away from the predominant site of virus replication during primary infection
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36. + T cell responses associated with control of viremia
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44. + memory T cell subsets in persistent EBV infection are differentiated by migratory receptor expression
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47. Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain