메뉴 건너뛰기




Volumn 164, Issue 1, 2000, Pages 208-216

Activated and memory CD8+ T cells can be distinguished by their cytokine profiles and phenotypic markers

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; CYTOKINE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; TUMOR NECROSIS FACTOR ALPHA;

EID: 0033961476     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.1.208     Document Type: Article
Times cited : (151)

References (63)
  • 1
    • 0028609462 scopus 로고
    • Virus infections in primary immunodeficiency
    • Webster, A. D. 1994. Virus infections in primary immunodeficiency. J. Clin. Pathol. 47:965.
    • (1994) J. Clin. Pathol. , vol.47 , pp. 965
    • Webster, A.D.1
  • 2
    • 0008590393 scopus 로고
    • Designing vaccines to induce cytotoxic T lymphocytes: Protection from lethal viral infection
    • F. Brown, R. Chanock, H. Ginsberg, and R. Lerner, eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor
    • Klavinskis, L. S., M. B. A. Oldstone, and J. L. Whitton. 1989. Designing vaccines to induce cytotoxic T lymphocytes: protection from lethal viral infection. In Vaccines 89: Modern Approaches to New Vaccines Including Prevention of AIDS. F. Brown, R. Chanock, H. Ginsberg, and R. Lerner, eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, p. 485.
    • (1989) Vaccines 89: Modern Approaches to New Vaccines Including Prevention of AIDS , pp. 485
    • Klavinskis, L.S.1    Oldstone, M.B.A.2    Whitton, J.L.3
  • 3
    • 0000042027 scopus 로고    scopus 로고
    • The immune response to viruses
    • B. N. Fields, D. M. Knipe, and P. M. Howley, eds. Raven Press, New York
    • Whitton, J. L., and M. B. A. Oldstone. 1996. The immune response to viruses. In Fields' Virology, 3rd Ed. B. N. Fields, D. M. Knipe, and P. M. Howley, eds. Raven Press, New York, p. 345.
    • (1996) Fields' Virology, 3rd Ed. , pp. 345
    • Whitton, J.L.1    Oldstone, M.B.A.2
  • 5
    • 0032007065 scopus 로고    scopus 로고
    • + T cells during an acute virus infection
    • + T cells during an acute virus infection. Immunity 8:167.
    • (1998) Immunity , vol.8 , pp. 167
    • Butz, E.A.1    Bevan, M.J.2
  • 6
    • 0031008386 scopus 로고    scopus 로고
    • Minimal bystander activation of CD8 T cells during the virus-induced polyclonal T cell response
    • Zarozinski, C. C., and R. M. Welsh. 1997. Minimal bystander activation of CD8 T cells during the virus-induced polyclonal T cell response. J. Exp. Med. 185: 1629.
    • (1997) J. Exp. Med. , vol.185 , pp. 1629
    • Zarozinski, C.C.1    Welsh, R.M.2
  • 7
    • 0028364545 scopus 로고
    • Activation-induced apoptosis in lymphocytes
    • Green, D. R., and D. W. Scott. 1994. Activation-induced apoptosis in lymphocytes. Curr. Opin. Immunol. 6:476.
    • (1994) Curr. Opin. Immunol. , vol.6 , pp. 476
    • Green, D.R.1    Scott, D.W.2
  • 8
    • 0029005587 scopus 로고
    • Activation-induced death of mature T cells in the regulation of immune responses
    • Russell, J. H. 1995. Activation-induced death of mature T cells in the regulation of immune responses. Curr. Opin. Immunol. 7:382.
    • (1995) Curr. Opin. Immunol. , vol.7 , pp. 382
    • Russell, J.H.1
  • 10
    • 0029986495 scopus 로고    scopus 로고
    • Human cytotoxic T-cell memory: Long-lived responses to vaccinia virus
    • Demkowicz, W. E. J., R. A. Littaua, J. Wang, and F. A. Ennis. 1996. Human cytotoxic T-cell memory: long-lived responses to vaccinia virus. J. Virol. 70: 2627.
    • (1996) J. Virol. , vol.70 , pp. 2627
    • Demkowicz, W.E.J.1    Littaua, R.A.2    Wang, J.3    Ennis, F.A.4
  • 13
    • 0023161452 scopus 로고
    • Distinction of virgin and memory T lymphocytes: Stable acquisition of the Pgp-1 glycoprotein concomitant with antigenic stimulation
    • Budd, R. C., J. C. Cerottini, C. Horvath, C. Bron, T. Pedrazzini, R. C. Howe, and H. R. Macdonald. 1987. Distinction of virgin and memory T lymphocytes: stable acquisition of the Pgp-1 glycoprotein concomitant with antigenic stimulation. J. Immunol. 138:3120.
    • (1987) J. Immunol. , vol.138 , pp. 3120
    • Budd, R.C.1    Cerottini, J.C.2    Horvath, C.3    Bron, C.4    Pedrazzini, T.5    Howe, R.C.6    Macdonald, H.R.7
  • 16
    • 0028085152 scopus 로고
    • T and B memory cells
    • Sprent, J. 1994. T and B memory cells. Cell 76:315.
    • (1994) Cell , vol.76 , pp. 315
    • Sprent, J.1
  • 17
    • 0030001674 scopus 로고    scopus 로고
    • Immunological memory and protective immunity: Understanding their relation
    • Ahmed, R., and D. Gray. 1996. Immunological memory and protective immunity: understanding their relation. Science 272:54.
    • (1996) Science , vol.272 , pp. 54
    • Ahmed, R.1    Gray, D.2
  • 18
    • 0032815039 scopus 로고    scopus 로고
    • The generation and maintenance of memory T and B cells
    • Dutton, R. W., S. L. Swain, and L. M. Bradley. 1999. The generation and maintenance of memory T and B cells. Immunol. Today 20:291.
    • (1999) Immunol. Today , vol.20 , pp. 291
    • Dutton, R.W.1    Swain, S.L.2    Bradley, L.M.3
  • 19
    • 0018753961 scopus 로고
    • MHC-restricted cytotoxic T cells: Studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness
    • Zinkernagel, R. M., and P. C. Doherty. 1979. MHC-restricted cytotoxic T cells: studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness. Adv. Immunol. 27:51.
    • (1979) Adv. Immunol. , vol.27 , pp. 51
    • Zinkernagel, R.M.1    Doherty, P.C.2
  • 20
    • 0021955350 scopus 로고
    • Virus and immune responses: Lymphocytic choriomeningitis virus as a prototype model of viral pathogenesis
    • Oldstone, M. B. A., R. Ahmed, J. Byrne, M. J. Buchmeier, Y. Riviere, and P. Southern. 1985. Virus and immune responses: lymphocytic choriomeningitis virus as a prototype model of viral pathogenesis. Br. Med. Bull. 41:70.
    • (1985) Br. Med. Bull. , vol.41 , pp. 70
    • Oldstone, M.B.A.1    Ahmed, R.2    Byrne, J.3    Buchmeier, M.J.4    Riviere, Y.5    Southern, P.6
  • 21
    • 0000912462 scopus 로고
    • Lymphocytic choriomeningitis virus CTL
    • Whitton, J. L. 1990. Lymphocytic choriomeningitis virus CTL. Semin. Virol. 1:257.
    • (1990) Semin. Virol. , vol.1 , pp. 257
    • Whitton, J.L.1
  • 22
    • 0028345963 scopus 로고
    • Cerebral expression of multiple cytokine genes in mice with lymphocytic choriomeningitis
    • Campbell, I. L., M. V. Hobbs, P. Kemper, and M. B. A. Oldstone. 1994. Cerebral expression of multiple cytokine genes in mice with lymphocytic choriomeningitis. J. Immunol. 152:716.
    • (1994) J. Immunol. , vol.152 , pp. 716
    • Campbell, I.L.1    Hobbs, M.V.2    Kemper, P.3    Oldstone, M.B.A.4
  • 24
    • 0032184763 scopus 로고    scopus 로고
    • + T cells during acute infection with lymphocytic choriomeningitis virus
    • + T cells during acute infection with lymphocytic choriomeningitis virus. J. Immunol. 161:3215.
    • (1998) J. Immunol. , vol.161 , pp. 3215
    • Varga, S.M.1    Welsh, R.M.2
  • 25
    • 0031668697 scopus 로고    scopus 로고
    • Long-term CD4 Th1 and Th2 memory following acute lymphocytic choriomeningitis virus infection
    • Whitmire, J. K., M. S. Asano, K. Murali-Krishna, M. Suresh, and R. Ahmed. 1998. Long-term CD4 Th1 and Th2 memory following acute lymphocytic choriomeningitis virus infection. J. Virol. 72:8281.
    • (1998) J. Virol. , vol.72 , pp. 8281
    • Whitmire, J.K.1    Asano, M.S.2    Murali-Krishna, K.3    Suresh, M.4    Ahmed, R.5
  • 27
    • 0021225388 scopus 로고
    • Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice: Role in suppression of cytotoxic T lymphocyte response and viral persistence
    • Ahmed, R., A. Salmi, L. D. Butler, J. M. Chiller, and M. B. A. Oldstone. 1984. Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice: role in suppression of cytotoxic T lymphocyte response and viral persistence. J. Exp. Med. 160:521.
    • (1984) J. Exp. Med. , vol.160 , pp. 521
    • Ahmed, R.1    Salmi, A.2    Butler, L.D.3    Chiller, J.M.4    Oldstone, M.B.A.5
  • 28
    • 0021227280 scopus 로고
    • Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus: Clearance of virus in vivo
    • Byrne, J. A., and M. B. A. Oldslone. 1984. Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus: clearance of virus in vivo. J. Virol. 51:682.
    • (1984) J. Virol. , vol.51 , pp. 682
    • Byrne, J.A.1    Oldslone, M.B.A.2
  • 30
    • 0025720569 scopus 로고
    • Immune response against lymphocytic choriomeningitis virus infection in mice without CD8 expression
    • Fung-Leung, W. P., T. M. Kundig, R. M. Zinkernagel, and T. W. Mak. 1991. Immune response against lymphocytic choriomeningitis virus infection in mice without CD8 expression. J. Exp. Med. 174:1425.
    • (1991) J. Exp. Med. , vol.174 , pp. 1425
    • Fung-Leung, W.P.1    Kundig, T.M.2    Zinkernagel, R.M.3    Mak, T.W.4
  • 33
    • 0024474289 scopus 로고
    • Molecular analyses of a five-amino-acid cytotoxic T-lymphocyte (CTL) epitope: An immunodominant region which induces nonreciprocal CTL cross-reactivity
    • Whitton, J. L., A. Tishon, H. Lewicki, J. R. Gebhard, T. Cook, M. S. Salvato, E. Joly, and M. B. A. Oldstone. 1989. Molecular analyses of a five-amino-acid cytotoxic T-lymphocyte (CTL) epitope: an immunodominant region which induces nonreciprocal CTL cross-reactivity. J. Virol. 63:4303.
    • (1989) J. Virol. , vol.63 , pp. 4303
    • Whitton, J.L.1    Tishon, A.2    Lewicki, H.3    Gebhard, J.R.4    Cook, T.5    Salvato, M.S.6    Joly, E.7    Oldstone, M.B.A.8
  • 35
    • 0032506129 scopus 로고    scopus 로고
    • + T cells in the liver during the control and resolution phases of influenza pneumonia
    • + T cells in the liver during the control and resolution phases of influenza pneumonia. Proc. Natl. Acad. Sci. USA 95:13812.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13812
    • Belz, G.T.1    Altman, J.D.2    Doherty, P.C.3
  • 37
    • 0030967752 scopus 로고    scopus 로고
    • Bone marrow contains virus-specific cytotoxic T lymphocytes
    • Slifka, M. K., J. K. Whitmire, and R. Ahmed. 1997. Bone marrow contains virus-specific cytotoxic T lymphocytes. Blood 90:2103.
    • (1997) Blood , vol.90 , pp. 2103
    • Slifka, M.K.1    Whitmire, J.K.2    Ahmed, R.3
  • 38
    • 0033548496 scopus 로고    scopus 로고
    • Linear differentiation of cytotoxic effectors into memory T lymphocytes
    • Opferman, J. T., B. T. Ober, and P. G. Ashton-Rickardt. 1999. Linear differentiation of cytotoxic effectors into memory T lymphocytes. Science 283:1745.
    • (1999) Science , vol.283 , pp. 1745
    • Opferman, J.T.1    Ober, B.T.2    Ashton-Rickardt, P.G.3
  • 40
    • 0031154754 scopus 로고    scopus 로고
    • Cytolytically active memory CTL present in lymphocytic choriomeningitis virus-immune mice after clearance of virus infection
    • Selin, L. K., and R. M. Welsh. 1997. Cytolytically active memory CTL present in lymphocytic choriomeningitis virus-immune mice after clearance of virus infection. J. Immunol. 158:5366.
    • (1997) J. Immunol. , vol.158 , pp. 5366
    • Selin, L.K.1    Welsh, R.M.2
  • 41
    • 0031446517 scopus 로고    scopus 로고
    • A functional and kinetic comparison of antiviral effector and memory cytotoxic T lymphocyte populations in vivo and in vitro
    • Ehl, S., P. Klenerman, P. Aichele, H. Hengartner, and R. M. Zinkernagel. 1997. A functional and kinetic comparison of antiviral effector and memory cytotoxic T lymphocyte populations in vivo and in vitro. Eur. J. Immunol. 27:3404.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 3404
    • Ehl, S.1    Klenerman, P.2    Aichele, P.3    Hengartner, H.4    Zinkernagel, R.M.5
  • 42
    • 0032921486 scopus 로고    scopus 로고
    • Distinct kinetics of cytokine production and cytolysis in effector and memory T cells after viral infection
    • Bachmann, M. F., M. Barner, A. Viola, and M. Kopf. 1999. Distinct kinetics of cytokine production and cytolysis in effector and memory T cells after viral infection. Eur. J. Immunol. 29:291.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 291
    • Bachmann, M.F.1    Barner, M.2    Viola, A.3    Kopf, M.4
  • 43
    • 0031128038 scopus 로고    scopus 로고
    • Protein sorting and secretion during CTL killing
    • Griffiths, G. M. 1997. Protein sorting and secretion during CTL killing. Semin. Immunol. 9:109.
    • (1997) Semin. Immunol. , vol.9 , pp. 109
    • Griffiths, G.M.1
  • 45
    • 0026717674 scopus 로고
    • The pathophysiology of tumor necrosis factors
    • Vassalli, P. 1992. The pathophysiology of tumor necrosis factors. Annu. Rev. Immunol. 10:411.
    • (1992) Annu. Rev. Immunol. , vol.10 , pp. 411
    • Vassalli, P.1
  • 46
    • 0032005791 scopus 로고    scopus 로고
    • Local and systemic cytokine responses during experimental human influenza A virus infection: Relation to symptom formation and host defense
    • Hayden, F. G., R. Fritz, M. C. Lobo, W. Alvord, W. Strober, and S. E. Straus. 1998. Local and systemic cytokine responses during experimental human influenza A virus infection: relation to symptom formation and host defense. J Clin. Invest. 101:643.
    • (1998) J Clin. Invest. , vol.101 , pp. 643
    • Hayden, F.G.1    Fritz, R.2    Lobo, M.C.3    Alvord, W.4    Strober, W.5    Straus, S.E.6
  • 48
    • 0032476684 scopus 로고    scopus 로고
    • Protective heterologous antiviral immunity and enhanced immunopathogenesis mediated by memory T cell populations
    • Selin, L. K., S. M. Varga, I. C. Wong, and R. M. Welsh. 1998. Protective heterologous antiviral immunity and enhanced immunopathogenesis mediated by memory T cell populations. J. Exp. Med. 188:1705.
    • (1998) J. Exp. Med. , vol.188 , pp. 1705
    • Selin, L.K.1    Varga, S.M.2    Wong, I.C.3    Welsh, R.M.4
  • 49
    • 0029044650 scopus 로고
    • Neuropathogenic actions of cytokines assessed in transgenie mice
    • Campbell, I. L. 1995. Neuropathogenic actions of cytokines assessed in transgenie mice. Int. J. Dev. Neurosci. 13:275.
    • (1995) Int. J. Dev. Neurosci. , vol.13 , pp. 275
    • Campbell, I.L.1
  • 51
    • 0033542458 scopus 로고    scopus 로고
    • Modeling T-cell memory by genetic marking of memory T cells in vivo
    • Jacob, J., and D. Baltimore. 1999. Modeling T-cell memory by genetic marking of memory T cells in vivo. Nature 399:593.
    • (1999) Nature , vol.399 , pp. 593
    • Jacob, J.1    Baltimore, D.2
  • 52
    • 0033553620 scopus 로고    scopus 로고
    • Inactivation of misselected CD8 t cells by CD8 gene methylation and cell death
    • Pestano, G. A., Y. Zhou, L. A. Trimble, J. Daley, G. F. Weber, and H. Cantor. 1999. Inactivation of misselected CD8 T cells by CD8 gene methylation and cell death. Science 284:1187.
    • (1999) Science , vol.284 , pp. 1187
    • Pestano, G.A.1    Zhou, Y.2    Trimble, L.A.3    Daley, J.4    Weber, G.F.5    Cantor, H.6
  • 54
    • 0030694234 scopus 로고    scopus 로고
    • The emerging role of CTLA-4 as an immune attenuator
    • Thompson, C. B., and J. P. Allison. 1997. The emerging role of CTLA-4 as an immune attenuator. Immunity 7:445.
    • (1997) Immunity , vol.7 , pp. 445
    • Thompson, C.B.1    Allison, J.P.2
  • 55
    • 0029899783 scopus 로고    scopus 로고
    • CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells
    • Krummel, M. F., and J. P. Allison. 1996. CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells. J. Exp. Med. 183:2533.
    • (1996) J. Exp. Med. , vol.183 , pp. 2533
    • Krummel, M.F.1    Allison, J.P.2
  • 56
    • 0029953858 scopus 로고    scopus 로고
    • CTLA-4 ligation blocks CD28-dependent T cell activation
    • Walunas, T. L., C. Y. Bakker, and J. A. Bluestone. 1996. CTLA-4 ligation blocks CD28-dependent T cell activation. J. Exp. Med. 183:2541.
    • (1996) J. Exp. Med. , vol.183 , pp. 2541
    • Walunas, T.L.1    Bakker, C.Y.2    Bluestone, J.A.3
  • 58
    • 0028867420 scopus 로고
    • Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
    • Tivol, E. A., F. Borriello, A. N. Schweitzer, W. P. Lynch, J. A. Bluestone, and A. H. Sharpe. 1995. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 3:541.
    • (1995) Immunity , vol.3 , pp. 541
    • Tivol, E.A.1    Borriello, F.2    Schweitzer, A.N.3    Lynch, W.P.4    Bluestone, J.A.5    Sharpe, A.H.6
  • 60
    • 0030740572 scopus 로고    scopus 로고
    • Normal thymic selection, normal viability and decreased lymphoproliferation in T cell receptor-transgenic CTLa-4-deficient mice
    • Waterhouse, P., M. F. Bachmann, J. M. Penninger, P. S. Ohashi, and T. W. Mak. 1997. Normal thymic selection, normal viability and decreased lymphoproliferation in T cell receptor-transgenic CTLA-4-deficient mice. Eur. J. Immunol. 27: 1887.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1887
    • Waterhouse, P.1    Bachmann, M.F.2    Penninger, J.M.3    Ohashi, P.S.4    Mak, T.W.5
  • 62
    • 0345368071 scopus 로고    scopus 로고
    • Is CTLA-4 a negative regulator for T-cell activation?
    • Liu, Y. 1997. Is CTLA-4 a negative regulator for T-cell activation? Immunol. Today 18:569.
    • (1997) Immunol. Today , vol.18 , pp. 569
    • Liu, Y.1
  • 63
    • 0032568524 scopus 로고    scopus 로고
    • B7-CTLA4 interaction enhances both production of antitumor cytotoxic T lymphocytes and resistance to tumor challenge
    • Zheng, P., Y. Wu, Y. Guo, C. Lee, and Y. Liu. 1998. B7-CTLA4 interaction enhances both production of antitumor cytotoxic T lymphocytes and resistance to tumor challenge. Proc. Natl. Acad. Sci. USA 95:6284.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 6284
    • Zheng, P.1    Wu, Y.2    Guo, Y.3    Lee, C.4    Liu, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.