-
1
-
-
0032580348
-
Human gene therapy
-
Anderson W.F. Human gene therapy. Nature. 392:1998;25-30.
-
(1998)
Nature
, vol.392
, pp. 25-30
-
-
Anderson, W.F.1
-
2
-
-
0035030198
-
Delivery systems intended for in vivo gene therapy of cancer: Targeting and replication competent viral vectors
-
Galanis E., Vile R., Russell S.J. Delivery systems intended for in vivo gene therapy of cancer: targeting and replication competent viral vectors. Crit. Rev. Oncol. Hematol. 38:2001;177-192.
-
(2001)
Crit. Rev. Oncol. Hematol.
, vol.38
, pp. 177-192
-
-
Galanis, E.1
Vile, R.2
Russell, S.J.3
-
3
-
-
0034997403
-
Non-viral vectors in cancer gene therapy: Principles and progress
-
Schatzlein A.G. Non-viral vectors in cancer gene therapy: principles and progress. Anticancer Drugs. 12:2001;275-304.
-
(2001)
Anticancer Drugs
, vol.12
, pp. 275-304
-
-
Schatzlein, A.G.1
-
4
-
-
0031052263
-
Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5
-
Bergelson J.M., Cunningham J.A., Droguett G.et al. Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5. Science. 275:1997;1320-1323.
-
(1997)
Science
, vol.275
, pp. 1320-1323
-
-
Bergelson, J.M.1
Cunningham, J.A.2
Droguett, G.3
-
5
-
-
0028937785
-
Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses
-
Yang Y., Li Q., Ertl H.C.et al. Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses. J. Virol. 69:1995;2004-2015.
-
(1995)
J. Virol.
, vol.69
, pp. 2004-2015
-
-
Yang, Y.1
Li, Q.2
Ertl, H.C.3
-
6
-
-
0033756217
-
Update on adenovirus and its vectors
-
Russell W.C. Update on adenovirus and its vectors. J. Gen. Virol. 81:2000;2573-2604.
-
(2000)
J. Gen. Virol.
, vol.81
, pp. 2573-2604
-
-
Russell, W.C.1
-
7
-
-
0032942152
-
A system for the propagation of adenoviral vectors with genetically modified receptor specificities
-
Douglas J.T., Miller C.R., Kim M.et al. A system for the propagation of adenoviral vectors with genetically modified receptor specificities. Nat. Biotechnol. 17:1999;470-475.
-
(1999)
Nat. Biotechnol.
, vol.17
, pp. 470-475
-
-
Douglas, J.T.1
Miller, C.R.2
Kim, M.3
-
9
-
-
0035904982
-
Conditional gene targeting for cancer gene therapy
-
Haviv Y.S., Curiel D.T. Conditional gene targeting for cancer gene therapy. Adv. Drug Deliv. Rev. 53:2001;135-154.
-
(2001)
Adv. Drug Deliv. Rev.
, vol.53
, pp. 135-154
-
-
Haviv, Y.S.1
Curiel, D.T.2
-
10
-
-
0034105702
-
Prodrug-activating systems in suicide gene therapy
-
Springer C.J., Niculescu-Duvaz I. Prodrug-activating systems in suicide gene therapy. J. Clin. Invest. 105:2000;1161-1167.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1161-1167
-
-
Springer, C.J.1
Niculescu-Duvaz, I.2
-
14
-
-
0000565243
-
Apoptosis in tumorigenesis and cancer therapy
-
McGill G. Apoptosis in tumorigenesis and cancer therapy. Front. Biosci. 2:1997;d353-d379.
-
(1997)
Front. Biosci.
, vol.2
, pp. 353-d379
-
-
McGill, G.1
-
15
-
-
0029972806
-
P53: Puzzle and paradigm
-
Ko L.J., Prives C. p53: puzzle and paradigm. Genes Dev. 10:1996;1054-1072.
-
(1996)
Genes Dev.
, vol.10
, pp. 1054-1072
-
-
Ko, L.J.1
Prives, C.2
-
16
-
-
0026649648
-
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
-
Momand J., Zambetti G.P., Olson D.C.et al. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell. 69:1992;1237-1245.
-
(1992)
Cell
, vol.69
, pp. 1237-1245
-
-
Momand, J.1
Zambetti, G.P.2
Olson, D.C.3
-
17
-
-
0034177304
-
How to activate p53
-
Caspari T. How to activate p53. Curr. Biol. 10:2000;R315-R317.
-
(2000)
Curr. Biol.
, vol.10
, pp. 315-R317
-
-
Caspari, T.1
-
18
-
-
0027496935
-
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
-
Harper J.W., Adami G.R., Wei N.et al. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell. 75:1993;805-816.
-
(1993)
Cell
, vol.75
, pp. 805-816
-
-
Harper, J.W.1
Adami, G.R.2
Wei, N.3
-
20
-
-
0033215387
-
Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a
-
Murphy M., Ahn J., Walker K.K.et al. Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a. Genes Dev. 13:1999;2490-2501.
-
(1999)
Genes Dev.
, vol.13
, pp. 2490-2501
-
-
Murphy, M.1
Ahn, J.2
Walker, K.K.3
-
21
-
-
0029802591
-
P53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells
-
Chen X., Ko L.J., Jayaraman L.et al. p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells. Genes Dev. 10:1996;2438-2451.
-
(1996)
Genes Dev.
, vol.10
, pp. 2438-2451
-
-
Chen, X.1
Ko, L.J.2
Jayaraman, L.3
-
22
-
-
0034717014
-
Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling
-
Marchenko N.D., Zaika A., Moll U.M. Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling. J. Biol. Chem. 275:2000;16202-16212.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 16202-16212
-
-
Marchenko, N.D.1
Zaika, A.2
Moll, U.M.3
-
23
-
-
0030941458
-
P53, the cellular gatekeeper for growth and division
-
Levine A.J. p53, the cellular gatekeeper for growth and division. Cell. 88:1997;323-331.
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
24
-
-
0027451668
-
P53-dependent apoptosis modulates the cytotoxicity of anticancer agents
-
Lowe S.W., Ruley H.E., Jacks T.et al. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell. 74:1993;957-967.
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
-
25
-
-
0036272911
-
P53 gene mutations: Case study of a clinical marker for solid tumors
-
Liu M.C., Gelmann E.P. P53 gene mutations: case study of a clinical marker for solid tumors. Semin. Oncol. 29:2002;246-257.
-
(2002)
Semin. Oncol.
, vol.29
, pp. 246-257
-
-
Liu, M.C.1
Gelmann, E.P.2
-
26
-
-
0031828248
-
Cell death and cancer: Replacement of apoptotic genes and inactivation of death suppressor genes in therapy
-
Favrot M., Coll J.L., Louis N.et al. Cell death and cancer: replacement of apoptotic genes and inactivation of death suppressor genes in therapy. Gene Ther. 5:1998;728-739.
-
(1998)
Gene Ther.
, vol.5
, pp. 728-739
-
-
Favrot, M.1
Coll, J.L.2
Louis, N.3
-
27
-
-
0025611503
-
Genetic mechanisms of tumor suppression by the human p53 gene
-
Chen P.L., Chen Y.M., Bookstein R.et al. Genetic mechanisms of tumor suppression by the human p53 gene. Science. 250:1990;1576-1580.
-
(1990)
Science
, vol.250
, pp. 1576-1580
-
-
Chen, P.L.1
Chen, Y.M.2
Bookstein, R.3
-
28
-
-
0025784539
-
Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
-
Yonish-Rouach E., Resnitzky D., Lotem J.et al. Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature. 352:1991;345-347.
-
(1991)
Nature
, vol.352
, pp. 345-347
-
-
Yonish-Rouach, E.1
Resnitzky, D.2
Lotem, J.3
-
29
-
-
0028143201
-
Therapeutic effect of a retroviral wild-type p53 expression vector in an orthotopic lung cancer model
-
Fujiwara T., Cai D.W., Georges R.N.et al. Therapeutic effect of a retroviral wild-type p53 expression vector in an orthotopic lung cancer model. J. Natl. Cancer Inst. 86:1994;1458-1462.
-
(1994)
J. Natl. Cancer Inst.
, vol.86
, pp. 1458-1462
-
-
Fujiwara, T.1
Cai, D.W.2
Georges, R.N.3
-
30
-
-
0031084922
-
Efficacy of p53 adenovirus-mediated gene therapy against human breast cancer xenografts
-
Nielsen L.L., Dell J., Maxwell E.et al. Efficacy of p53 adenovirus-mediated gene therapy against human breast cancer xenografts. Cancer Gene Ther. 4:1997;129-138.
-
(1997)
Cancer Gene Ther.
, vol.4
, pp. 129-138
-
-
Nielsen, L.L.1
Dell, J.2
Maxwell, E.3
-
31
-
-
0027818396
-
A retroviral wild-type p53 expression vector penetrates human lung cancer spheroids and inhibits growth by inducing apoptosis
-
Fujiwara T., Grimm E.A., Mukhopadhyay T.et al. A retroviral wild-type p53 expression vector penetrates human lung cancer spheroids and inhibits growth by inducing apoptosis. Cancer Res. 53:1993;4129-4133.
-
(1993)
Cancer Res.
, vol.53
, pp. 4129-4133
-
-
Fujiwara, T.1
Grimm, E.A.2
Mukhopadhyay, T.3
-
32
-
-
0028231586
-
Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild-type p53 gene
-
Fujiwara T., Grimm E.A., Mukhopadhyay T.et al. Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild-type p53 gene. Cancer Res. 54:1994;2287-2291.
-
(1994)
Cancer Res.
, vol.54
, pp. 2287-2291
-
-
Fujiwara, T.1
Grimm, E.A.2
Mukhopadhyay, T.3
-
33
-
-
0029904706
-
Adenovirus-based transfer of wild-type p53 gene increases ovarian tumor radiosensitivity
-
Gallardo D., Drazan K.E., McBride W.H. Adenovirus-based transfer of wild-type p53 gene increases ovarian tumor radiosensitivity. Cancer Res. 56:1996;4891-4893.
-
(1996)
Cancer Res.
, vol.56
, pp. 4891-4893
-
-
Gallardo, D.1
Drazan, K.E.2
McBride, W.H.3
-
34
-
-
0029835487
-
Gene therapy for lung cancer: Enhancement of tumor suppression by a combination of sequential systemic cisplatin and adenovirus-mediated p53 gene transfer
-
discussion 1376-7
-
Nguyen D.M., Spitz F.R., Yen N.et al. Gene therapy for lung cancer: enhancement of tumor suppression by a combination of sequential systemic cisplatin and adenovirus-mediated p53 gene transfer. J. Thorac. Cardiovasc. Surg. 112:1996;1372-1376. discussion 1376-7.
-
(1996)
J. Thorac. Cardiovasc. Surg.
, vol.112
, pp. 1372-1376
-
-
Nguyen, D.M.1
Spitz, F.R.2
Yen, N.3
-
35
-
-
0031944077
-
Adenovirus-mediated p53 gene therapy and paclitaxel have synergistic efficacy in models of human head and neck, ovarian, prostate, and breast cancer
-
Nielsen L.L., Lipari P., Dell J.et al. Adenovirus-mediated p53 gene therapy and paclitaxel have synergistic efficacy in models of human head and neck, ovarian, prostate, and breast cancer. Clin. Cancer Res. 4:1998;835-846.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 835-846
-
-
Nielsen, L.L.1
Lipari, P.2
Dell, J.3
-
36
-
-
0032990031
-
Adenovirus-mediated p53 gene therapy has greater efficacy when combined with chemotherapy against human head and neck, ovarian, prostate, and breast cancer
-
Gurnani M., Lipari P., Dell J.et al. Adenovirus-mediated p53 gene therapy has greater efficacy when combined with chemotherapy against human head and neck, ovarian, prostate, and breast cancer. Cancer Chemother. Pharmacol. 44:1999;143-151.
-
(1999)
Cancer Chemother. Pharmacol.
, vol.44
, pp. 143-151
-
-
Gurnani, M.1
Lipari, P.2
Dell, J.3
-
37
-
-
0033664328
-
Development and validation of sensitive assays to quantitate gene expression after p53 gene therapy and paclitaxel chemotherapy using in vivo dosing in tumor xenograft models
-
Wen S.F., Xie L., McDonald M.et al. Development and validation of sensitive assays to quantitate gene expression after p53 gene therapy and paclitaxel chemotherapy using in vivo dosing in tumor xenograft models. Cancer Gene Ther. 7:2000;1469-1480.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 1469-1480
-
-
Wen, S.F.1
Xie, L.2
McDonald, M.3
-
38
-
-
0031755588
-
Bystander effect in the adenovirus-mediated wild-type p53 gene therapy model of human squamous cell carcinoma of the head and neck
-
Frank D.K., Frederick M.J., Liu T.J.et al. Bystander effect in the adenovirus-mediated wild-type p53 gene therapy model of human squamous cell carcinoma of the head and neck. Clin. Cancer Res. 4:1998;2521-2528.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 2521-2528
-
-
Frank, D.K.1
Frederick, M.J.2
Liu, T.J.3
-
39
-
-
0032902502
-
Recombinant adenovirus expressing wild-type p53 is antiangiogenic: A proposed mechanism for bystander effect
-
Nishizaki M., Fujiwara T., Tanida T.et al. Recombinant adenovirus expressing wild-type p53 is antiangiogenic: a proposed mechanism for bystander effect. Clin. Cancer Res. 5:1999;1015-1023.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 1015-1023
-
-
Nishizaki, M.1
Fujiwara, T.2
Tanida, T.3
-
40
-
-
0028060380
-
Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1
-
Dameron K.M., Volpert O.V., Tainsky M.A.et al. Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science. 265:1994;1582-1584.
-
(1994)
Science
, vol.265
, pp. 1582-1584
-
-
Dameron, K.M.1
Volpert, O.V.2
Tainsky, M.A.3
-
41
-
-
0036138149
-
Aerosol delivery of PEI-p53 complexes inhibits B16-F10 lung metastases through regulation of angiogenesis
-
Gautam A., Densmore C.L., Melton S.et al. Aerosol delivery of PEI-p53 complexes inhibits B16-F10 lung metastases through regulation of angiogenesis. Cancer Gene Ther. 9:2002;28-36.
-
(2002)
Cancer Gene Ther.
, vol.9
, pp. 28-36
-
-
Gautam, A.1
Densmore, C.L.2
Melton, S.3
-
42
-
-
0034670020
-
Contribution of CD95 ligand-induced neutrophil infiltration to the bystander effect in p53 gene therapy for human cancer
-
Waku T., Fujiwara T., Shao J.et al. Contribution of CD95 ligand-induced neutrophil infiltration to the bystander effect in p53 gene therapy for human cancer. J. Immunol. 165:2000;5884-5890.
-
(2000)
J. Immunol.
, vol.165
, pp. 5884-5890
-
-
Waku, T.1
Fujiwara, T.2
Shao, J.3
-
44
-
-
9544244796
-
Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer
-
Roth J.A., Nguyen D., Lawrence D.D.et al. Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer. Nat. Med. 2:1996;985-991.
-
(1996)
Nat. Med.
, vol.2
, pp. 985-991
-
-
Roth, J.A.1
Nguyen, D.2
Lawrence, D.D.3
-
45
-
-
17344365479
-
A phase I study of adenovirus-mediated wild-type p53 gene transfer in patients with advanced non-small cell lung cancer
-
Schuler M., Rochlitz C., Horowitz J.A.et al. A phase I study of adenovirus-mediated wild-type p53 gene transfer in patients with advanced non-small cell lung cancer. Hum. Gene Ther. 9:1998;2075-2082.
-
(1998)
Hum. Gene Ther.
, vol.9
, pp. 2075-2082
-
-
Schuler, M.1
Rochlitz, C.2
Horowitz, J.A.3
-
46
-
-
0033526357
-
Adenovirus-mediated p53 gene transfer in advanced non-small-cell lung cancer
-
Swisher S.G., Roth J.A., Nemunaitis J.et al. Adenovirus-mediated p53 gene transfer in advanced non-small-cell lung cancer. J. Natl. Cancer Inst. 91:1999;763-771.
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 763-771
-
-
Swisher, S.G.1
Roth, J.A.2
Nemunaitis, J.3
-
47
-
-
0032608925
-
CT-guided intratumoral gene therapy in non-small-cell lung cancer
-
Kauczor H.U., Schuler M., Heussel C.P.et al. CT-guided intratumoral gene therapy in non-small-cell lung cancer. Eur. Radiol. 9:1999;292-296.
-
(1999)
Eur. Radiol.
, vol.9
, pp. 292-296
-
-
Kauczor, H.U.1
Schuler, M.2
Heussel, C.P.3
-
48
-
-
0034085041
-
Cellular and humoral immune responses to adenovirus and p53 protein antigens in patients following intratumoral injection of an adenovirus vector expressing wild-type. P53 (Ad-p53)
-
Yen N., Ioannides C.G., Xu K.et al. Cellular and humoral immune responses to adenovirus and p53 protein antigens in patients following intratumoral injection of an adenovirus vector expressing wild-type. P53 (Ad-p53). Cancer Gene Ther. 7:2000;530-536.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 530-536
-
-
Yen, N.1
Ioannides, C.G.2
Xu, K.3
-
49
-
-
0033785831
-
Adenoviral-mediated p53 gene transfer to non-small cell lung cancer through endobronchial injection
-
Weill D., Mack M., Roth J.et al. Adenoviral-mediated p53 gene transfer to non-small cell lung cancer through endobronchial injection. Chest. 118:2000;966-970.
-
(2000)
Chest
, vol.118
, pp. 966-970
-
-
Weill, D.1
Mack, M.2
Roth, J.3
-
50
-
-
0033950285
-
Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer
-
Nemunaitis J., Swisher S.G., Timmons T.et al. Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer. J. Clin. Oncol. 18:2000;609-622.
-
(2000)
J. Clin. Oncol.
, vol.18
, pp. 609-622
-
-
Nemunaitis, J.1
Swisher, S.G.2
Timmons, T.3
-
51
-
-
0031828108
-
Gene therapy for non-small cell lung cancer: A preliminary report of a phase I trial of adenoviral p53 gene replacement
-
Roth J.A., Swisher S.G., Merritt J.A.et al. Gene therapy for non-small cell lung cancer: a preliminary report of a phase I trial of adenoviral p53 gene replacement. Semin. Oncol. 25:1998;33-37.
-
(1998)
Semin. Oncol.
, vol.25
, pp. 33-37
-
-
Roth, J.A.1
Swisher, S.G.2
Merritt, J.A.3
-
52
-
-
0033781847
-
P21 gene expression as an indicator for the activity of adenovirus-p53 gene therapy in non-small cell lung cancer patients
-
Boulay J.L., Perruchoud A.P., Reuter J.et al. P21 gene expression as an indicator for the activity of adenovirus-p53 gene therapy in non-small cell lung cancer patients. Cancer Gene Ther. 7:2000;1215-1219.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 1215-1219
-
-
Boulay, J.L.1
Perruchoud, A.P.2
Reuter, J.3
-
53
-
-
0035868848
-
Adenovirus-mediated wild-type p53 gene transfer in patients receiving chemotherapy for advanced non-small-cell lung cancer: Results of a multicenter phase II study
-
Schuler M., Herrmann R., De Greve J.L.et al. Adenovirus-mediated wild-type p53 gene transfer in patients receiving chemotherapy for advanced non-small-cell lung cancer: results of a multicenter phase II study. J. Clin. Oncol. 19:2001;1750-1758.
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 1750-1758
-
-
Schuler, M.1
Herrmann, R.2
De Greve, J.L.3
-
54
-
-
0031750168
-
Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma
-
Clayman G.L., el-Naggar A.K., Lippman S.M.et al. Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma. J. Clin. Oncol. 16:1998;2221-2232.
-
(1998)
J. Clin. Oncol.
, vol.16
, pp. 2221-2232
-
-
Clayman, G.L.1
El-Naggar, A.K.2
Lippman, S.M.3
-
55
-
-
0032809839
-
Adenovirus-mediated wild-type p53 gene transfer as a surgical adjuvant in advanced head and neck cancers
-
Clayman G.L., Frank D.K., Bruso P.A.et al. Adenovirus-mediated wild-type p53 gene transfer as a surgical adjuvant in advanced head and neck cancers. Clin. Cancer Res. 5:1999;1715-1722.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 1715-1722
-
-
Clayman, G.L.1
Frank, D.K.2
Bruso, P.A.3
-
56
-
-
0036019371
-
A phase I/II trial of rAd/p53 (SCH 58500) gene replacement in recurrent ovarian cancer
-
Buller R.E., Runnebaum I.B., Karlan B.Y.et al. A phase I/II trial of rAd/p53 (SCH 58500) gene replacement in recurrent ovarian cancer. Cancer Gene Ther. 9:2002;553-566.
-
(2002)
Cancer Gene Ther.
, vol.9
, pp. 553-566
-
-
Buller, R.E.1
Runnebaum, I.B.2
Karlan, B.Y.3
-
57
-
-
0036019372
-
Long term follow-up of patients with recurrent ovarian cancer after Ad p53 gene replacement with SCH 58500
-
Buller R.E., Shahin M.S., Horowitz J.A.et al. Long term follow-up of patients with recurrent ovarian cancer after Ad p53 gene replacement with SCH 58500. Cancer Gene Ther. 9:2002;567-572.
-
(2002)
Cancer Gene Ther.
, vol.9
, pp. 567-572
-
-
Buller, R.E.1
Shahin, M.S.2
Horowitz, J.A.3
-
58
-
-
0033914837
-
Biological activity and safety of adenoviral vector-expressed wild-type p53 after intratumoral injection in melanoma and breast cancer patients with p53-overexpressing tumors
-
Dummer R., Bergh J., Karlsson Y.et al. Biological activity and safety of adenoviral vector-expressed wild-type p53 after intratumoral injection in melanoma and breast cancer patients with p53-overexpressing tumors. Cancer Gene Ther. 7:2000;1069-1076.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 1069-1076
-
-
Dummer, R.1
Bergh, J.2
Karlsson, Y.3
-
59
-
-
0037083558
-
Successful adenovirus-mediated wild-type p53 gene transfer in patients with bladder cancer by intravesical vector instillation
-
Kuball J., Wen S.F., Leissner J.et al. Successful adenovirus-mediated wild-type p53 gene transfer in patients with bladder cancer by intravesical vector instillation. J. Clin. Oncol. 20:2002;957-965.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 957-965
-
-
Kuball, J.1
Wen, S.F.2
Leissner, J.3
-
60
-
-
0036093592
-
Induction of p53-specific immune responses in colorectal cancer patients receiving a recombinant ALVAC-p53 candidate vaccine
-
Van Der Burg S.H., Menon A.G., Redeker A.et al. Induction of p53-specific immune responses in colorectal cancer patients receiving a recombinant ALVAC-p53 candidate vaccine. Clin. Cancer Res. 8:2002;1019-1027.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 1019-1027
-
-
Van Der Burg, S.H.1
Menon, A.G.2
Redeker, A.3
-
61
-
-
0034167356
-
Ad5CMVp53 gene therapy for locally advanced prostate cancer - Where do we stand?
-
Sweeney P., Pisters L.L. Ad5CMVp53 gene therapy for locally advanced prostate cancer - where do we stand? World J. Urol. 18:2000;121-124.
-
(2000)
World J. Urol.
, vol.18
, pp. 121-124
-
-
Sweeney, P.1
Pisters, L.L.2
-
62
-
-
10244234032
-
Adenovirus-mediated p53 gene transfer suppresses growth of human glioblastoma cells in vitro and in vivo
-
Kock H., Harris M.P., Anderson S.C.et al. Adenovirus-mediated p53 gene transfer suppresses growth of human glioblastoma cells in vitro and in vivo. Int. J. Cancer. 67:1996;808-815.
-
(1996)
Int. J. Cancer
, vol.67
, pp. 808-815
-
-
Kock, H.1
Harris, M.P.2
Anderson, S.C.3
-
63
-
-
0030020689
-
Adenovirus-mediated transfer of the p53 gene produces rapid and generalized death of human glioma cells via apoptosis
-
Gomez-Manzano C., Fueyo J., Kyritsis A.P.et al. Adenovirus-mediated transfer of the p53 gene produces rapid and generalized death of human glioma cells via apoptosis. Cancer Res. 56:1996;694-699.
-
(1996)
Cancer Res.
, vol.56
, pp. 694-699
-
-
Gomez-Manzano, C.1
Fueyo, J.2
Kyritsis, A.P.3
-
64
-
-
0029043098
-
Adenovirus-mediated p53 gene delivery inhibits 9L glioma growth in rats
-
Badie B., Drazan K.E., Kramar M.H.et al. Adenovirus-mediated p53 gene delivery inhibits 9L glioma growth in rats. Neurol. Res. 17:1995;209-216.
-
(1995)
Neurol. Res.
, vol.17
, pp. 209-216
-
-
Badie, B.1
Drazan, K.E.2
Kramar, M.H.3
-
65
-
-
0033668590
-
Adenoviral vector-mediated gene transfer: Timing of wild-type p53 gene expression in vivo and effect of tumor transduction on survival in a rat glioma brachytherapy model
-
Bampoe J., Glen J., Hubbard S.L.et al. Adenoviral vector-mediated gene transfer: timing of wild-type p53 gene expression in vivo and effect of tumor transduction on survival in a rat glioma brachytherapy model. J. Neurooncol. 49:2000;27-39.
-
(2000)
J. Neurooncol.
, vol.49
, pp. 27-39
-
-
Bampoe, J.1
Glen, J.2
Hubbard, S.L.3
-
66
-
-
0027428633
-
Detection of p53 alterations in human astrocytomas using frozen tissue sections for the polymerase chain reaction
-
Aka K., Bruner J.M., Bondy M.L.et al. Detection of p53 alterations in human astrocytomas using frozen tissue sections for the polymerase chain reaction. J. Neurooncol. 16:1993;125-133.
-
(1993)
J. Neurooncol.
, vol.16
, pp. 125-133
-
-
Aka, K.1
Bruner, J.M.2
Bondy, M.L.3
-
67
-
-
0031869758
-
Predicting response to cancer chemotherapy: The role of p53
-
Weller M. Predicting response to cancer chemotherapy: the role of p53. Cell Tissue Res. 292:1998;435-445.
-
(1998)
Cell Tissue Res.
, vol.292
, pp. 435-445
-
-
Weller, M.1
-
68
-
-
0033118475
-
Apoptosis, p53, and tumor cell sensitivity to anticancer agents
-
Brown J.M., Wouters B.G. Apoptosis, p53, and tumor cell sensitivity to anticancer agents. Cancer Res. 59:1999;1391-1399.
-
(1999)
Cancer Res.
, vol.59
, pp. 1391-1399
-
-
Brown, J.M.1
Wouters, B.G.2
-
69
-
-
0035138823
-
P53 induction and apoptosis in response to radio- and chemotherapy in vivo is tumor-type-dependent
-
Kemp C.J., Sun S., Gurley K.E. p53 induction and apoptosis in response to radio- and chemotherapy in vivo is tumor-type-dependent. Cancer Res. 61:2001;327-332.
-
(2001)
Cancer Res.
, vol.61
, pp. 327-332
-
-
Kemp, C.J.1
Sun, S.2
Gurley, K.E.3
-
70
-
-
0034668186
-
New insights into p53 regulation and gene therapy for cancer
-
Zeimet A.G., Riha K., Berger J.et al. New insights into p53 regulation and gene therapy for cancer. Biochem. Pharmacol. 60:2000;1153-1163.
-
(2000)
Biochem. Pharmacol.
, vol.60
, pp. 1153-1163
-
-
Zeimet, A.G.1
Riha, K.2
Berger, J.3
-
71
-
-
0033985682
-
EGF receptor and p21WAF1 expression are reciprocally altered as ME-180 cervical carcinoma cells progress from high to low cisplatin sensitivity
-
Donato N.J., Perez M., Kang H.et al. EGF receptor and p21WAF1 expression are reciprocally altered as ME-180 cervical carcinoma cells progress from high to low cisplatin sensitivity. Clin. Cancer Res. 6:2000;193-202.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 193-202
-
-
Donato, N.J.1
Perez, M.2
Kang, H.3
-
72
-
-
0028098165
-
Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas
-
Cordon-Cardo C., Latres E., Drobnjak M.et al. Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas. Cancer Res. 54:1994;794-799.
-
(1994)
Cancer Res.
, vol.54
, pp. 794-799
-
-
Cordon-Cardo, C.1
Latres, E.2
Drobnjak, M.3
-
73
-
-
0028823416
-
In vivo gene therapy with p53 or p21 adenovirus for prostate cancer
-
Eastham J.A., Hall S.J., Sehgal I.et al. In vivo gene therapy with p53 or p21 adenovirus for prostate cancer. Cancer Res. 55:1995;5151-5155.
-
(1995)
Cancer Res.
, vol.55
, pp. 5151-5155
-
-
Eastham, J.A.1
Hall, S.J.2
Sehgal, I.3
-
74
-
-
0033967137
-
A binary adenoviral vector system for expressing high levels of the proapoptotic gene bax
-
Kagawa S., Pearson S.A., Ji L.et al. A binary adenoviral vector system for expressing high levels of the proapoptotic gene bax. Gene Ther. 7:2000;75-79.
-
(2000)
Gene Ther.
, vol.7
, pp. 75-79
-
-
Kagawa, S.1
Pearson, S.A.2
Ji, L.3
-
75
-
-
0034065319
-
Cancer gene therapy mediated by CTS1, a p53 derivative: Advantage over wild-type p53 in growth inhibition of human tumors overexpressing MDM2
-
Bougeret C., Virone-Oddos A., Adeline E.et al. Cancer gene therapy mediated by CTS1, a p53 derivative: advantage over wild-type p53 in growth inhibition of human tumors overexpressing MDM2. Cancer Gene Ther. 7:2000;789-798.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 789-798
-
-
Bougeret, C.1
Virone-Oddos, A.2
Adeline, E.3
-
76
-
-
85047698445
-
Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis
-
Hemmati P.G., Gillissen B., von Haefen C.et al. Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis. Oncogene. 21:2002;3149-3161.
-
(2002)
Oncogene
, vol.21
, pp. 3149-3161
-
-
Hemmati, P.G.1
Gillissen, B.2
Von Haefen, C.3
-
77
-
-
0030033729
-
Adenovirus-mediated p16/CDKN2 gene transfer induces growth arrest and modifies the transformed phenotype of glioma cells
-
Fueyo J., Gomez-Manzano C., Yung W.K.et al. Adenovirus-mediated p16/CDKN2 gene transfer induces growth arrest and modifies the transformed phenotype of glioma cells. Oncogene. 12:1996;103-110.
-
(1996)
Oncogene
, vol.12
, pp. 103-110
-
-
Fueyo, J.1
Gomez-Manzano, C.2
Yung, W.K.3
-
78
-
-
0034905621
-
In vitro and in vivo adenovirus-mediated p53 and p16 tumor suppressor therapy in ovarian cancer
-
Modesitt S.C., Ramirez P., Zu Z.et al. In vitro and in vivo adenovirus-mediated p53 and p16 tumor suppressor therapy in ovarian cancer. Clin. Cancer Res. 7:2001;1765-1772.
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 1765-1772
-
-
Modesitt, S.C.1
Ramirez, P.2
Zu, Z.3
-
79
-
-
0030813584
-
Adenovirus-mediated overexpression of the transcription factor E2F-1 induces apoptosis in human breast and ovarian carcinoma cell lines and does not require p53
-
Hunt K.K., Deng J., Liu T.J.et al. Adenovirus-mediated overexpression of the transcription factor E2F-1 induces apoptosis in human breast and ovarian carcinoma cell lines and does not require p53. Cancer Res. 57:1997;4722-4726.
-
(1997)
Cancer Res.
, vol.57
, pp. 4722-4726
-
-
Hunt, K.K.1
Deng, J.2
Liu, T.J.3
-
80
-
-
0344188096
-
An adenovirus mutant that replicates selectively in p53-deficient human tumor cells
-
Bischoff J.R., Kirn D.H., Williams A.et al. An adenovirus mutant that replicates selectively in p53-deficient human tumor cells. Science. 274:1996;373-376.
-
(1996)
Science
, vol.274
, pp. 373-376
-
-
Bischoff, J.R.1
Kirn, D.H.2
Williams, A.3
-
81
-
-
0025251915
-
Domains required for in vitro association between the cellular p53 and the adenovirus 2 E1B 55K proteins
-
Kao C.C., Yew P.R., Berk A.J. Domains required for in vitro association between the cellular p53 and the adenovirus 2 E1B 55K proteins. Virology. 179:1990;806-814.
-
(1990)
Virology
, vol.179
, pp. 806-814
-
-
Kao, C.C.1
Yew, P.R.2
Berk, A.J.3
-
82
-
-
0026639932
-
The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins
-
Rao L., Debbas M., Sabbatini P.et al. The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins. Proc. Natl. Acad. Sci. U.S.A. 89:1992;7742-7746.
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 7742-7746
-
-
Rao, L.1
Debbas, M.2
Sabbatini, P.3
-
83
-
-
0023099280
-
Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection
-
Barker D.D., Berk A.J. Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection. Virology. 156:1987;107-121.
-
(1987)
Virology
, vol.156
, pp. 107-121
-
-
Barker, D.D.1
Berk, A.J.2
-
84
-
-
0034161976
-
In vivo antitumor activity of ONYX-015 is influenced by p53 status and is augmented by radiotherapy
-
Rogulski K.R., Freytag S.O., Zhang K.et al. In vivo antitumor activity of ONYX-015 is influenced by p53 status and is augmented by radiotherapy. Cancer Res. 60:2000;1193-1196.
-
(2000)
Cancer Res.
, vol.60
, pp. 1193-1196
-
-
Rogulski, K.R.1
Freytag, S.O.2
Zhang, K.3
-
85
-
-
0035083288
-
Replication and cytolysis of an E1B-attenuated adenovirus in drug-resistant ovarian tumour cells is associated with reduced apoptosis
-
Ganly I., Kim Y.T., Hann B.et al. Replication and cytolysis of an E1B-attenuated adenovirus in drug-resistant ovarian tumour cells is associated with reduced apoptosis. Gene Ther. 8:2001;369-375.
-
(2001)
Gene Ther.
, vol.8
, pp. 369-375
-
-
Ganly, I.1
Kim, Y.T.2
Hann, B.3
-
86
-
-
0030917202
-
ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents
-
Heise C., Sampson-Johannes A., Williams A.et al. ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents. Nat. Med. 3:1997;639-645.
-
(1997)
Nat. Med.
, vol.3
, pp. 639-645
-
-
Heise, C.1
Sampson-Johannes, A.2
Williams, A.3
-
87
-
-
0031798440
-
P53 status does not determine outcome of E1B 55-kilodalton mutant adenovirus lytic infection
-
Goodrum F.D., Ornelles D.A. p53 status does not determine outcome of E1B 55-kilodalton mutant adenovirus lytic infection. J. Virol. 72:1998;9479-9490.
-
(1998)
J. Virol.
, vol.72
, pp. 9479-9490
-
-
Goodrum, F.D.1
Ornelles, D.A.2
-
88
-
-
0031743945
-
Replication of ONYX-015, a potential anticancer adenovirus, is independent of p53 status in tumor cells
-
Rothmann T., Hengstermann A., Whitaker N.J.et al. Replication of ONYX-015, a potential anticancer adenovirus, is independent of p53 status in tumor cells. J. Virol. 72:1998;9470-9478.
-
(1998)
J. Virol.
, vol.72
, pp. 9470-9478
-
-
Rothmann, T.1
Hengstermann, A.2
Whitaker, N.J.3
-
89
-
-
0033011866
-
The replicative capacities of large E1B-null group A and group C adenoviruses are independent of host cell p53 status
-
Turnell A.S., Grand R.J., Gallimore P.H. The replicative capacities of large E1B-null group A and group C adenoviruses are independent of host cell p53 status. J. Virol. 73:1999;2074-2083.
-
(1999)
J. Virol.
, vol.73
, pp. 2074-2083
-
-
Turnell, A.S.1
Grand, R.J.2
Gallimore, P.H.3
-
90
-
-
0033623250
-
Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015)
-
Ries S.J., Brandts C.H., Chung A.S.et al. Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015). Nat. Med. 6:2000;1128-1133.
-
(2000)
Nat. Med.
, vol.6
, pp. 1128-1133
-
-
Ries, S.J.1
Brandts, C.H.2
Chung, A.S.3
-
91
-
-
0033152894
-
Intravenous administration of ONYX-015, a selectively replicating adenovirus, induces antitumoral efficacy
-
Heise C.C., Williams A.M., Xue S.et al. Intravenous administration of ONYX-015, a selectively replicating adenovirus, induces antitumoral efficacy. Cancer Res. 59:1999;2623-2628.
-
(1999)
Cancer Res.
, vol.59
, pp. 2623-2628
-
-
Heise, C.C.1
Williams, A.M.2
Xue, S.3
-
92
-
-
12944328660
-
A phase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer
-
Ganly I., Kirn D., Eckhardt G.et al. A phase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer. Clin. Cancer Res. 6:2000;798-806.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 798-806
-
-
Ganly, I.1
Kirn, D.2
Eckhardt, G.3
-
93
-
-
0033693231
-
Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55 kDa gene-deleted adenovirus, in patients with advanced head and neck cancer: A phase II trial
-
Nemunaitis J., Ganly I., Khuri F.et al. Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55 kDa gene-deleted adenovirus, in patients with advanced head and neck cancer: a phase II trial. Cancer Res. 60:2000;6359-6366.
-
(2000)
Cancer Res.
, vol.60
, pp. 6359-6366
-
-
Nemunaitis, J.1
Ganly, I.2
Khuri, F.3
-
94
-
-
0035863458
-
Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer
-
Nemunaitis J., Khuri F., Ganly I.et al. Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer. J. Clin. Oncol. 19:2001;289-298.
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 289-298
-
-
Nemunaitis, J.1
Khuri, F.2
Ganly, I.3
-
95
-
-
0033831080
-
A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer
-
Khuri F.R., Nemunaitis J., Ganly I.et al. A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat. Med. 6:2000;879-885.
-
(2000)
Nat. Med.
, vol.6
, pp. 879-885
-
-
Khuri, F.R.1
Nemunaitis, J.2
Ganly, I.3
-
96
-
-
0034990761
-
Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: Safety, feasibility and biological activity
-
Nemunaitis J., Cunningham C., Buchanan A.et al. Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity. Gene Ther. 8:2001;746-759.
-
(2001)
Gene Ther.
, vol.8
, pp. 746-759
-
-
Nemunaitis, J.1
Cunningham, C.2
Buchanan, A.3
-
97
-
-
85047699490
-
Clinical trial of E1B-deleted adenovirus (dl1520) gene therapy for hepatocellular carcinoma
-
Habib N., Salama H., Abd El Latif Abu Median A.et al. Clinical trial of E1B-deleted adenovirus (dl1520) gene therapy for hepatocellular carcinoma. Cancer Gene Ther. 9:2002;254-259.
-
(2002)
Cancer Gene Ther.
, vol.9
, pp. 254-259
-
-
Habib, N.1
Salama, H.2
Abd El Latif Abu Median, A.3
-
98
-
-
0035835373
-
E1B-deleted adenovirus (dl1520) gene therapy for patients with primary and secondary liver tumors
-
Habib N.A., Sarraf C.E., Mitry R.R.et al. E1B-deleted adenovirus (dl1520) gene therapy for patients with primary and secondary liver tumors. Hum. Gene Ther. 12:2001;219-226.
-
(2001)
Hum. Gene Ther.
, vol.12
, pp. 219-226
-
-
Habib, N.A.1
Sarraf, C.E.2
Mitry, R.R.3
-
99
-
-
0035177690
-
Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: A phase I trial
-
Reid T., Galanis E., Abbruzzese J.et al. Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: a phase I trial. Gene Ther. 8:2001;1618-1626.
-
(2001)
Gene Ther.
, vol.8
, pp. 1618-1626
-
-
Reid, T.1
Galanis, E.2
Abbruzzese, J.3
-
100
-
-
0037087621
-
Phase I trial of intraperitoneal injection of the E1B-55-kDa-gene-deleted adenovirus ONYX-015 (dl1520) given on days 1 through 5 every 3 weeks in patients with recurrent/refractory epithelial ovarian cancer
-
Vasey P.A., Shulman L.N., Campos S.et al. Phase I trial of intraperitoneal injection of the E1B-55-kDa-gene-deleted adenovirus ONYX-015 (dl1520) given on days 1 through 5 every 3 weeks in patients with recurrent/refractory epithelial ovarian cancer. J. Clin. Oncol. 20:2002;1562-1569.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 1562-1569
-
-
Vasey, P.A.1
Shulman, L.N.2
Campos, S.3
-
101
-
-
0035076823
-
Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: A phase I trial
-
Mulvihill S., Warren R., Venook A.et al. Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: a phase I trial. Gene Ther. 8:2001;308-315.
-
(2001)
Gene Ther.
, vol.8
, pp. 308-315
-
-
Mulvihill, S.1
Warren, R.2
Venook, A.3
-
102
-
-
0001673475
-
A phase I/II trial of intratumoral endoscopic injection of Onyx-015 with intravenous gemcitabine in unresectable pancreatic carcinoma
-
[abstract]
-
Hecht J.R., Abbruzzese J., Bedford R.et al. A phase I/II trial of intratumoral endoscopic injection of Onyx-015 with intravenous gemcitabine in unresectable pancreatic carcinoma. Proc. Am. Soc. Clin. Oncol. 19:2000;1039. [abstract].
-
(2000)
Proc. Am. Soc. Clin. Oncol.
, vol.19
, pp. 1039
-
-
Hecht, J.R.1
Abbruzzese, J.2
Bedford, R.3
-
103
-
-
0022263759
-
Adenovirus E1B proteins are required for accumulation of late viral mRNA and for effects on cellular mRNA translation and transport
-
Babiss L.E., Ginsberg H.S., Darnell J.E. Jr. Adenovirus E1B proteins are required for accumulation of late viral mRNA and for effects on cellular mRNA translation and transport. Mol. Cell. Biol. 5:1985;2552-2558.
-
(1985)
Mol. Cell. Biol.
, vol.5
, pp. 2552-2558
-
-
Babiss, L.E.1
Ginsberg, H.S.2
Darnell J.E., Jr.3
-
104
-
-
0035881594
-
P14(ARF) modulates the cytolytic effect of ONYX-015 in mesothelioma cells with wild-type p53
-
Yang C.T., You L., Uematsu K.et al. p14(ARF) modulates the cytolytic effect of ONYX-015 in mesothelioma cells with wild-type p53. Cancer Res. 61:2001;5959-5963.
-
(2001)
Cancer Res.
, vol.61
, pp. 5959-5963
-
-
Yang, C.T.1
You, L.2
Uematsu, K.3
-
105
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D., Weinberg R.A. The hallmarks of cancer. Cell. 100:2000;57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
106
-
-
0033782862
-
An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy
-
Heise C., Hermiston T., Johnson L.et al. An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy. Nat. Med. 6:2000;1134-1139.
-
(2000)
Nat. Med.
, vol.6
, pp. 1134-1139
-
-
Heise, C.1
Hermiston, T.2
Johnson, L.3
-
107
-
-
19044386714
-
Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents
-
Johnson L., Shen A., Boyle L.et al. Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents. Cancer Cell. 1:2002;325-337.
-
(2002)
Cancer Cell
, vol.1
, pp. 325-337
-
-
Johnson, L.1
Shen, A.2
Boyle, L.3
-
108
-
-
0029558740
-
Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression
-
Jiang H., Lin J.J., Su Z.Z.et al. Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression. Oncogene. 11:1995;2477-2486.
-
(1995)
Oncogene
, vol.11
, pp. 2477-2486
-
-
Jiang, H.1
Lin, J.J.2
Su, Z.Z.3
-
109
-
-
0034637535
-
Identification of a novel ligand-receptor pair constitutively activated by ras oncogenes
-
Zhang R., Tan Z., Liang P. Identification of a novel ligand-receptor pair constitutively activated by ras oncogenes. J. Biol. Chem. 275:2000;24436-24443.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 24436-24443
-
-
Zhang, R.1
Tan, Z.2
Liang, P.3
-
110
-
-
0035950553
-
Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties
-
Huang E.Y., Madireddi M.T., Gopalkrishnan R.V.et al. Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties. Oncogene. 20:2001;7051-7063.
-
(2001)
Oncogene
, vol.20
, pp. 7051-7063
-
-
Huang, E.Y.1
Madireddi, M.T.2
Gopalkrishnan, R.V.3
-
111
-
-
0035951795
-
Identification of the functional interleukin-22 (IL-22) receptor complex: The IL-10R2 chain (IL-10Rbeta) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes
-
Kotenko S.V., Izotova L.S., Mirochnitchenko O.V.et al. Identification of the functional interleukin-22 (IL-22) receptor complex: the IL-10R2 chain (IL-10Rbeta) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes. J. Biol. Chem. 276:2001;2725-2732.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 2725-2732
-
-
Kotenko, S.V.1
Izotova, L.S.2
Mirochnitchenko, O.V.3
-
112
-
-
0034475080
-
Mda-7, a novel melanoma differentiation associated gene with promise for cancer gene therapy
-
Madireddi M.T., Su Z.Z., Young C.S.H.et al. Mda-7, a novel melanoma differentiation associated gene with promise for cancer gene therapy. Adv. Exp. Med. Biol. 465:2000;239-261.
-
(2000)
Adv. Exp. Med. Biol.
, vol.465
, pp. 239-261
-
-
Madireddi, M.T.1
Su, Z.Z.2
Young, C.S.H.3
-
113
-
-
0036779507
-
mda-7/IL-24: Signaling and functional role
-
Sarkar D, Su Z-Z, Lebedeva IV, et al. mda-7/IL-24: signaling and functional role. BioTechniques 2002;Suppl:30-9.
-
(2002)
BioTechniques
, Issue.SUPPL.
, pp. 30-39
-
-
Sarkar, D.1
Su, Z.-Z.2
Lebedeva, I.V.3
-
114
-
-
0037097637
-
The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24
-
Caudell E.G., Mumm J.B., Poindexter N.et al. The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24. J. Immunol. 168:2002;6041-6046.
-
(2002)
J. Immunol.
, vol.168
, pp. 6041-6046
-
-
Caudell, E.G.1
Mumm, J.B.2
Poindexter, N.3
-
115
-
-
0029808333
-
The melanoma differentiation associated gene mda-7 suppresses cancer cell growth
-
Jiang H., Su Z.Z., Lin J.J.et al. The melanoma differentiation associated gene mda-7 suppresses cancer cell growth. Proc. Natl. Acad. Sci. U.S.A. 93:1996;9160-9165.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 9160-9165
-
-
Jiang, H.1
Su, Z.Z.2
Lin, J.J.3
-
116
-
-
0035317682
-
Melanoma differentiation associated gene-7 (mda-7): A novel anti-tumor gene for cancer gene therapy
-
Mhashilkar A.M., Schrock R.D., Hindi M.et al. Melanoma differentiation associated gene-7 (mda-7): a novel anti-tumor gene for cancer gene therapy. Mol. Med. 7:2001;271-282.
-
(2001)
Mol. Med.
, vol.7
, pp. 271-282
-
-
Mhashilkar, A.M.1
Schrock, R.D.2
Hindi, M.3
-
117
-
-
0032564357
-
The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice
-
Su Z.Z., Madireddi M.T., Lin J.J.et al. The cancer growth suppressor gene mda-7 selectively induces apoptosis in human breast cancer cells and inhibits tumor growth in nude mice. Proc. Natl. Acad. Sci. U.S.A. 95:1998;14400-14405.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 14400-14405
-
-
Su, Z.Z.1
Madireddi, M.T.2
Lin, J.J.3
-
118
-
-
0035479966
-
Down-regulated melanoma differentiation associated gene (mda-7) expression in human melanomas
-
Ekmekcioglu S., Ellerhorst J., Mhashilkar A.M.et al. Down-regulated melanoma differentiation associated gene (mda-7) expression in human melanomas. Int. J. Cancer. 94:2001;54-59.
-
(2001)
Int. J. Cancer
, vol.94
, pp. 54-59
-
-
Ekmekcioglu, S.1
Ellerhorst, J.2
Mhashilkar, A.M.3
-
120
-
-
85047695547
-
The cancer growth suppressing gene mda-7 induces apoptosis selectively in human melanoma cells
-
Lebedeva I.V., Su Z.Z., Chang Y.et al. The cancer growth suppressing gene mda-7 induces apoptosis selectively in human melanoma cells. Oncogene. 21:2002;708-718.
-
(2002)
Oncogene
, vol.21
, pp. 708-718
-
-
Lebedeva, I.V.1
Su, Z.Z.2
Chang, Y.3
-
121
-
-
0034502591
-
Tumor-suppressive effects by adenovirus-mediated mda-7 gene transfer in non-small cell lung cancer cell in vitro
-
Saeki T., Mhashilkar A., Chada S.et al. Tumor-suppressive effects by adenovirus-mediated mda-7 gene transfer in non-small cell lung cancer cell in vitro. Gene Ther. 7:2000;2051-2057.
-
(2000)
Gene Ther.
, vol.7
, pp. 2051-2057
-
-
Saeki, T.1
Mhashilkar, A.2
Chada, S.3
-
123
-
-
0037089491
-
Adenoviral transfer of the melanoma differentiation-associated gene 7 (mda-7) induces apoptosis of lung cancer cells via up-regulation of the double-stranded RNA-dependent protein kinase (PKR)
-
Pataer A., Vorburger S.A., Barber G.N.et al. Adenoviral transfer of the melanoma differentiation-associated gene 7 (mda-7) induces apoptosis of lung cancer cells via up-regulation of the double-stranded RNA-dependent protein kinase (PKR). Cancer Res. 62:2002;2239-2243.
-
(2002)
Cancer Res.
, vol.62
, pp. 2239-2243
-
-
Pataer, A.1
Vorburger, S.A.2
Barber, G.N.3
-
124
-
-
0035964399
-
A combinatorial approach for selectively inducing programmed cell death in human pancreatic cancer cells
-
Su Z., Lebedeva I.V., Gopalkrishnan R.V.et al. A combinatorial approach for selectively inducing programmed cell death in human pancreatic cancer cells. Proc. Natl. Acad. Sci. U.S.A. 98:2001;10332-10337.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 10332-10337
-
-
Su, Z.1
Lebedeva, I.V.2
Gopalkrishnan, R.V.3
-
125
-
-
0037019174
-
Inhibition of human lung cancer growth following adenovirus-mediated mda-7 gene expression in vivo
-
Saeki T., Mhashilkar A., Swanson X.et al. Inhibition of human lung cancer growth following adenovirus-mediated mda-7 gene expression in vivo. Oncogene. 21:2002;4558-4566.
-
(2002)
Oncogene
, vol.21
, pp. 4558-4566
-
-
Saeki, T.1
Mhashilkar, A.2
Swanson, X.3
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