-
1
-
-
0029956081
-
Specific p53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients
-
Aas T, Borresen AL, Geisler S, Smith-Sorensen B, Johnsen H, Varhaug JE, Akslen LA, Lonning PE (1996) Specific p53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients. Nat Med 2:811-814
-
(1996)
Nat Med
, vol.2
, pp. 811-814
-
-
Aas, T.1
Borresen, A.L.2
Geisler, S.3
Smith-Sorensen, B.4
Johnsen, H.5
Varhaug, J.E.6
Akslen, L.A.7
Lonning, P.E.8
-
2
-
-
0030023846
-
Cleavage of retinoblastoma protein during apoptosis: An interleukin 1β-converting enzyme-like protease as candidate
-
An B, Dou QP (1996) Cleavage of retinoblastoma protein during apoptosis: an interleukin 1β-converting enzyme-like protease as candidate. Cancer Res 56:438-442
-
(1996)
Cancer Res
, vol.56
, pp. 438-442
-
-
An, B.1
Dou, Q.P.2
-
3
-
-
0028875410
-
Complete sequencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemic therapy and radiotherapy
-
Bergh J, Norberg T, Sjögren S, Lindgren A, Holmberg L (1995) Complete sequencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemic therapy and radiotherapy. Nat Med 1: 1029-1034
-
(1995)
Nat Med
, vol.1
, pp. 1029-1034
-
-
Bergh, J.1
Norberg, T.2
Sjögren, S.3
Lindgren, A.4
Holmberg, L.5
-
4
-
-
0028319289
-
Concomitant p53 gene mutation and increased radiosensitivity in rat lung embryo epithelial cells during neoplastic development
-
Biard DSF, Martin M, Rhun Y, Duthu A, Lefaix JL, May E, May P (1994) Concomitant p53 gene mutation and increased radiosensitivity in rat lung embryo epithelial cells during neoplastic development. Cancer Res 54:3361-3364
-
(1994)
Cancer Res
, vol.54
, pp. 3361-3364
-
-
Biard, D.S.F.1
Martin, M.2
Rhun, Y.3
Duthu, A.4
Lefaix, J.L.5
May, E.6
May, P.7
-
6
-
-
0029832231
-
In vitro evaluation of a p53-expressing adenovirus as an anticancer drug
-
Blagosklonny MV, El-Deiry WS (1996) In vitro evaluation of a p53-expressing adenovirus as an anticancer drug. Int J Cancer 67:386-392
-
(1996)
Int J Cancer
, vol.67
, pp. 386-392
-
-
Blagosklonny, M.V.1
El-Deiry, W.S.2
-
7
-
-
0027331811
-
p53 accumulation in ovarian carcinomas and its prognostic implications
-
Bosari S, Viale G, Radaeli U, Bossi P, Bonoldi E, Coggi G (1993) p53 accumulation in ovarian carcinomas and its prognostic implications. Hum Pathol 24:1175-1179
-
(1993)
Hum Pathol
, vol.24
, pp. 1175-1179
-
-
Bosari, S.1
Viale, G.2
Radaeli, U.3
Bossi, P.4
Bonoldi, E.5
Coggi, G.6
-
8
-
-
0027176479
-
p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines
-
Brachman DG, Beckett M, Graves D, Haraf D, Yokes E, Weichselbaum RR (1993) p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines. Cancer Res 53:3667-3669
-
(1993)
Cancer Res
, vol.53
, pp. 3667-3669
-
-
Brachman, D.G.1
Beckett, M.2
Graves, D.3
Haraf, D.4
Yokes, E.5
Weichselbaum, R.R.6
-
9
-
-
0030232710
-
The p53 gene as a modifier of intrinsic radiosensitivity: Implications for radiotherapy
-
Bristow RG, Benchimol S, Hill RP (1996) The p53 gene as a modifier of intrinsic radiosensitivity: implications for radiotherapy. Radiother Oncol 40:197-223
-
(1996)
Radiother Oncol
, vol.40
, pp. 197-223
-
-
Bristow, R.G.1
Benchimol, S.2
Hill, R.P.3
-
10
-
-
8044233696
-
p53 alterations are predictive of chemoresistance and aggressiveness in ovarian carcinomas: A molecular and immunohistochemical study
-
Buttitta F, Marchetti A, Gadduci A, Pellegrini S, Morganti M, Carnicelli V, Cosio S, Gagetti O, Genazzanui AR, Bevilaqua G (1997) p53 alterations are predictive of chemoresistance and aggressiveness in ovarian carcinomas: a molecular and immunohistochemical study. Br J Cancer 75:230-235
-
(1997)
Br J Cancer
, vol.75
, pp. 230-235
-
-
Buttitta, F.1
Marchetti, A.2
Gadduci, A.3
Pellegrini, S.4
Morganti, M.5
Carnicelli, V.6
Cosio, S.7
Gagetti, O.8
Genazzanui, A.R.9
Bevilaqua, G.10
-
11
-
-
0028070989
-
p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes
-
Caelles C, Helmberg A, Karin M (1994) p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes. Nature 370:220-223
-
(1994)
Nature
, vol.370
, pp. 220-223
-
-
Caelles, C.1
Helmberg, A.2
Karin, M.3
-
12
-
-
0029929672
-
Hypersensitivity of human testicular tumors to etoposide-induced apoptosis is associated with functional p53 and a high bax:bcl-2 ratio
-
Chresta CM, Masters JRW, Hickman JA (1996) Hypersensitivity of human testicular tumors to etoposide-induced apoptosis is associated with functional p53 and a high bax:bcl-2 ratio. Cancer Res 56:1834-1841
-
(1996)
Cancer Res
, vol.56
, pp. 1834-1841
-
-
Chresta, C.M.1
Masters, J.R.W.2
Hickman, J.A.3
-
13
-
-
0027258466
-
Thymocyte apoptosis induced by p53-dependent and independent pathways
-
Clarke AR, Purdie CA, Harrison DJ, Morris RG, Bird CC, Hooper ML, Wyllie AH (1993) Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 362:849-852
-
(1993)
Nature
, vol.362
, pp. 849-852
-
-
Clarke, A.R.1
Purdie, C.A.2
Harrison, D.J.3
Morris, R.G.4
Bird, C.C.5
Hooper, M.L.6
Wyllie, A.H.7
-
14
-
-
0031008749
-
p53, mutation frequency and apoptosis in the murine small intestine
-
Clarke AR, Howard LA, Harrison DJ, Winton DJ (1997) p53, mutation frequency and apoptosis in the murine small intestine. Oncogene 14:2015-2018
-
(1997)
Oncogene
, vol.14
, pp. 2015-2018
-
-
Clarke, A.R.1
Howard, L.A.2
Harrison, D.J.3
Winton, D.J.4
-
15
-
-
0027210981
-
Gain of function mutations in p 53
-
Dittmer S, Pati S, Zambetti G, Chu S, Teresky AK, Moore M, Foster D, Anderson RJ, Levine AJ (1993) Gain of function mutations in p 53. Nat Genet 4:42-46
-
(1993)
Nat Genet
, vol.4
, pp. 42-46
-
-
Dittmer, S.1
Pati, S.2
Zambetti, G.3
Chu, S.4
Teresky, A.K.5
Moore, M.6
Foster, D.7
Anderson, R.J.8
Levine, A.J.9
-
16
-
-
0028880293
-
The control of apoptosis and drug resistance in ovarian cancer: Influence of p53 and bcl-2
-
Eliopoulos AG, Kerr DJ, Herod J, Hodgkins L, Krajewski S, Reed JC, Young LS (1995) The control of apoptosis and drug resistance in ovarian cancer: influence of p53 and bcl-2. Oncogene 11:1217-1228
-
(1995)
Oncogene
, vol.11
, pp. 1217-1228
-
-
Eliopoulos, A.G.1
Kerr, D.J.2
Herod, J.3
Hodgkins, L.4
Krajewski, S.5
Reed, J.C.6
Young, L.S.7
-
17
-
-
0028171454
-
p53 gene mutations are associated with decreased sensitivity of human lymphoma cells to DNA damaging agents
-
Fan S, El-Deiry WS, Bae I, Freeman J, Jondle D, Bhatia K, Fornace AJ, Magrath I, Kohn KW, O'Connor PM (1994) p53 gene mutations are associated with decreased sensitivity of human lymphoma cells to DNA damaging agents. Cancer Res 54:5824-5830
-
(1994)
Cancer Res
, vol.54
, pp. 5824-5830
-
-
Fan, S.1
El-Deiry, W.S.2
Bae, I.3
Freeman, J.4
Jondle, D.5
Bhatia, K.6
Fornace, A.J.7
Magrath, I.8
Kohn, K.W.9
O'Connor, P.M.10
-
18
-
-
0028901034
-
Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline
-
Fan S, Smith ML, Rivet DJ, Duba D, Zhan Q, Kohn KW, Fornace AJ, O'Connor PM (1995) Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline. Cancer Res 55:1649-1654
-
(1995)
Cancer Res
, vol.55
, pp. 1649-1654
-
-
Fan, S.1
Smith, M.L.2
Rivet, D.J.3
Duba, D.4
Zhan, Q.5
Kohn, K.W.6
Fornace, A.J.7
O'Connor, P.M.8
-
19
-
-
0029935682
-
Involvement of the CD95 (APO-1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells
-
Friesen C, Herr I, Krammer PH, Debatin KM (1996) Involvement of the CD95 (APO-1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells. Nat Med 2:574-577
-
(1996)
Nat Med
, vol.2
, pp. 574-577
-
-
Friesen, C.1
Herr, I.2
Krammer, P.H.3
Debatin, K.M.4
-
20
-
-
0028231586
-
Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild-type p53 gene
-
Fujiwara T, Grimm EA, Mukhopadhyay T, Zhang WW, Owen-Schaub LB, Roth JA (1994) Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wild-type p53 gene. Cancer Res 54:2287-2291
-
(1994)
Cancer Res
, vol.54
, pp. 2287-2291
-
-
Fujiwara, T.1
Grimm, E.A.2
Mukhopadhyay, T.3
Zhang, W.W.4
Owen-Schaub, L.B.5
Roth, J.A.6
-
21
-
-
0031014097
-
Identification of p53 genetic suppressor elements which confer resistance to cisplatin
-
Gallagher WM, Cairney M, Schott B, Rominson IB, Brown R (1997) Identification of p53 genetic suppressor elements which confer resistance to cisplatin. Oncogene 14:185-193
-
(1997)
Oncogene
, vol.14
, pp. 185-193
-
-
Gallagher, W.M.1
Cairney, M.2
Schott, B.3
Rominson, I.B.4
Brown, R.5
-
22
-
-
0029904706
-
Adenovirus-based transfer of wild-type p53 gene increases ovarian tumor radiosensitivity
-
Gallardo D, Drazan KE, McBride WH (1996) Adenovirus-based transfer of wild-type p53 gene increases ovarian tumor radiosensitivity. Cancer Res 56:4891-4893
-
(1996)
Cancer Res
, vol.56
, pp. 4891-4893
-
-
Gallardo, D.1
Drazan, K.E.2
McBride, W.H.3
-
23
-
-
0029555339
-
Use of wild-type p53 to achieve complete treatment sensitization of tumor cells expressing endogenous mutant p53
-
Gjerset R, Turia ST, Sobol RE, Scalise JJ, Mercola D, Collins H, Hopkins PJ (1995) Use of wild-type p53 to achieve complete treatment sensitization of tumor cells expressing endogenous mutant p53. Mol Carcinog 14:275-285
-
(1995)
Mol Carcinog
, vol.14
, pp. 275-285
-
-
Gjerset, R.1
Turia, S.T.2
Sobol, R.E.3
Scalise, J.J.4
Mercola, D.5
Collins, H.6
Hopkins, P.J.7
-
24
-
-
0028071555
-
Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
-
Greenblatt MS, Bennett WP, Hollstein M, Harris CC (1994) Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 54:4855-4878
-
(1994)
Cancer Res
, vol.54
, pp. 4855-4878
-
-
Greenblatt, M.S.1
Bennett, W.P.2
Hollstein, M.3
Harris, C.C.4
-
25
-
-
9344266882
-
The p53 gene is a potent determinant of chemosensitivity and radiosensitivity in gastric and colorectal cancers
-
Hamada M, Fujiwara T, Hizuta A, Gochi A, Naomoto Y, Takakura N, Takahashi K, Roth JA, Tanaka N, Orita K (1996) The p53 gene is a potent determinant of chemosensitivity and radiosensitivity in gastric and colorectal cancers. J Cancer Res Clin Oncol 122:360-365
-
(1996)
J Cancer Res Clin Oncol
, vol.122
, pp. 360-365
-
-
Hamada, M.1
Fujiwara, T.2
Hizuta, A.3
Gochi, A.4
Naomoto, Y.5
Takakura, N.6
Takahashi, K.7
Roth, J.A.8
Tanaka, N.9
Orita, K.10
-
26
-
-
0031034762
-
p53 status affects the rate of the onset but not the overall extent of doxorubicin-induced cell death in Rat-1 fibroblasts constitutively expressing c-myc
-
Han JW, Dionne CA, Kedersha NL, Goldmacher VS (1997) p53 status affects the rate of the onset but not the overall extent of doxorubicin-induced cell death in Rat-1 fibroblasts constitutively expressing c-myc. Cancer Res 57:176-182
-
(1997)
Cancer Res
, vol.57
, pp. 176-182
-
-
Han, J.W.1
Dionne, C.A.2
Kedersha, N.L.3
Goldmacher, V.S.4
-
27
-
-
0029092356
-
Induction of apoptosis in HeLa cells by transactivation deficient p53
-
Haupt Y, Rowan S, Shaulian E, Vousden HK, Oren M (1995) Induction of apoptosis in HeLa cells by transactivation deficient p53. Genes Dev 9:2170-2183
-
(1995)
Genes Dev
, vol.9
, pp. 2170-2183
-
-
Haupt, Y.1
Rowan, S.2
Shaulian, E.3
Vousden, H.K.4
Oren, M.5
-
28
-
-
0030021996
-
Inactivation of p53 enhances sensitivity to multiple chemotherapeutic drugs
-
Hawkins DS, Demers GW, Galloway DA (1996) Inactivation of p53 enhances sensitivity to multiple chemotherapeutic drugs. Cancer Res 56:892-898
-
(1996)
Cancer Res
, vol.56
, pp. 892-898
-
-
Hawkins, D.S.1
Demers, G.W.2
Galloway, D.A.3
-
29
-
-
0029824596
-
Strange bedfellows in even stranger places: The role of ATM in meiotic cells, lymphocytes, tumors, and its functional links to p53
-
Hawley RS, Friend SH (1996) Strange bedfellows in even stranger places: the role of ATM in meiotic cells, lymphocytes, tumors, and its functional links to p53. Genes Dev 10:2383-2388
-
(1996)
Genes Dev
, vol.10
, pp. 2383-2388
-
-
Hawley, R.S.1
Friend, S.H.2
-
30
-
-
0030036839
-
Association of p53 gene mutation with decreased chemosensitivity in human malignant gliomas
-
Iwadate Y, Fujimoto S, Tagawa M, Namba H, Sueyoshi K, Hirose M, Sakiyama S (1996) Association of p53 gene mutation with decreased chemosensitivity in human malignant gliomas. Int J Cancer 69:236-240
-
(1996)
Int J Cancer
, vol.69
, pp. 236-240
-
-
Iwadate, Y.1
Fujimoto, S.2
Tagawa, M.3
Namba, H.4
Sueyoshi, K.5
Hirose, M.6
Sakiyama, S.7
-
31
-
-
0030974567
-
Inability to induce the alteration of tumorigenicity and chemosensitivity of p53-null human pancreatic carcinoma cells after the transduction of wild-type p53 gene
-
Kimuru M, Tagawa M, Takenaga K, Yamaguchi T, Saisho H, Nakagawara A, Sakiyama S (1997) Inability to induce the alteration of tumorigenicity and chemosensitivity of p53-null human pancreatic carcinoma cells after the transduction of wild-type p53 gene. Anticancer Res 17:879-884
-
(1997)
Anticancer Res
, vol.17
, pp. 879-884
-
-
Kimuru, M.1
Tagawa, M.2
Takenaga, K.3
Yamaguchi, T.4
Saisho, H.5
Nakagawara, A.6
Sakiyama, S.7
-
32
-
-
0028062685
-
Mutant p53 protein associated with chemosensitivity in breast cancer specimens
-
Koechli OR, Schaer GN, Seifert B, Hornung R, Haller U, Eppenberger U, Mueller H (1994) Mutant p53 protein associated with chemosensitivity in breast cancer specimens. Lancet 344:1647-1648
-
(1994)
Lancet
, vol.344
, pp. 1647-1648
-
-
Koechli, O.R.1
Schaer, G.N.2
Seifert, B.3
Hornung, R.4
Haller, U.5
Eppenberger, U.6
Mueller, H.7
-
33
-
-
0029112238
-
Viability of wild type p53-containing and p53-deficient tumor cells following anticancer treatment: The use of human papillomavirus E6 to target p53
-
Labrecque S, Matlashewski GJ (1995) Viability of wild type p53-containing and p53-deficient tumor cells following anticancer treatment: the use of human papillomavirus E6 to target p53. Oncogene 11:387-392
-
(1995)
Oncogene
, vol.11
, pp. 387-392
-
-
Labrecque, S.1
Matlashewski, G.J.2
-
34
-
-
0027285380
-
p53 mutations increase resistance to ionizing radiation
-
Lee JM, Bernstein A (1993) p53 mutations increase resistance to ionizing radiation. Proc Natl Acad Sci USA 90:5742-5746
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 5742-5746
-
-
Lee, J.M.1
Bernstein, A.2
-
35
-
-
0029038135
-
Apoptosis, cancer and the p53 tumour suppressor gene
-
Lee JM, Bernstein A (1995) Apoptosis, cancer and the p53 tumour suppressor gene. Cancer Metastasis Rev 14:149-161
-
(1995)
Cancer Metastasis Rev
, vol.14
, pp. 149-161
-
-
Lee, J.M.1
Bernstein, A.2
-
36
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine AJ (1997) p53, the cellular gatekeeper for growth and division. Cell 85:323-331
-
(1997)
Cell
, vol.85
, pp. 323-331
-
-
Levine, A.J.1
-
37
-
-
0027451668
-
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
-
Lowe SW, Ruley HE, Jacks T, Housman DE (1993a) p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74:957-967
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
Housman, D.E.4
-
38
-
-
0027319521
-
p53 is required for radiation-induced apoptosis in mouse thymocytes
-
Lowe SW, Schmitt EM, Smith SW, Osborne BA, Jacks T (1993b) p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362:847-849
-
(1993)
Nature
, vol.362
, pp. 847-849
-
-
Lowe, S.W.1
Schmitt, E.M.2
Smith, S.W.3
Osborne, B.A.4
Jacks, T.5
-
39
-
-
0027944206
-
p53 status and the efficacy of cancer therapy in vivo
-
Lowe SW, Bodis S, McClatchey A, Remington L, Ruley HE, Fisher DE, Housman DE, Jacks T (1994) p53 status and the efficacy of cancer therapy in vivo. Science 266:807-810
-
(1994)
Science
, vol.266
, pp. 807-810
-
-
Lowe, S.W.1
Bodis, S.2
McClatchey, A.3
Remington, L.4
Ruley, H.E.5
Fisher, D.E.6
Housman, D.E.7
Jacks, T.8
-
40
-
-
0028999374
-
p53 protein overexpression and chemosensitivity in breast cancer
-
Makris A, Powels TJ, Dowsett M, Allred C (1995) p53 protein overexpression and chemosensitivity in breast cancer. Lancet 345:1181-1182
-
(1995)
Lancet
, vol.345
, pp. 1181-1182
-
-
Makris, A.1
Powels, T.J.2
Dowsett, M.3
Allred, C.4
-
41
-
-
0028861937
-
p53-independent death and p53-induced protection against apoptosis in fibroblasts treated with chemotherapeutic drugs
-
Malcomson RDG, Oren M, Wyllie AH, Harrison DJ (1995) p53-independent death and p53-induced protection against apoptosis in fibroblasts treated with chemotherapeutic drugs. Br J Cancer 72:952-957
-
(1995)
Br J Cancer
, vol.72
, pp. 952-957
-
-
Malcomson, R.D.G.1
Oren, M.2
Wyllie, A.H.3
Harrison, D.J.4
-
42
-
-
0029637709
-
p53 protein overexpression and chemosensitivity in breast Cancer
-
Mathieu MC, Koscielny S, Bihan ML, Spielmann M, Arriagada M (1995) p53 protein overexpression and chemosensitivity in breast Cancer. Lancet 345:1182
-
(1995)
Lancet
, vol.345
, pp. 1182
-
-
Mathieu, M.C.1
Koscielny, S.2
Bihan, M.L.3
Spielmann, M.4
Arriagada, M.5
-
43
-
-
0027931008
-
Cell cycle arrests and radiosensitivity of human tumor cell lines: Dependence on wild-type p53 for radiosensitivity
-
McIlwrath AJ, Vasey PA, Ross GM, Brown R (1994) Cell cycle arrests and radiosensitivity of human tumor cell lines: dependence on wild-type p53 for radiosensitivity. Cancer Res 54:3718-3722
-
(1994)
Cancer Res
, vol.54
, pp. 3718-3722
-
-
McIlwrath, A.J.1
Vasey, P.A.2
Ross, G.M.3
Brown, R.4
-
44
-
-
0028047723
-
The role of p53 in spontaneous apoptosis and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice
-
Merritt AJ, Potten CS, Kemp CJ, Hickman JA, Balmain A, Lane DP, Hall PA (1994) The role of p53 in spontaneous apoptosis and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice. Cancer Res 54:614-617
-
(1994)
Cancer Res
, vol.54
, pp. 614-617
-
-
Merritt, A.J.1
Potten, C.S.2
Kemp, C.J.3
Hickman, J.A.4
Balmain, A.5
Lane, D.P.6
Hall, P.A.7
-
45
-
-
0025111068
-
Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53
-
Michalowitz D, Halevy O, Oren M (1990) Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53. Cell 62:671-680
-
(1990)
Cell
, vol.62
, pp. 671-680
-
-
Michalowitz, D.1
Halevy, O.2
Oren, M.3
-
46
-
-
0030910037
-
p53 and ATM: Cell cycle, cell death, and cancer
-
Morgan SE, Kastan MB (1997) p53 and ATM: cell cycle, cell death, and cancer. Adv Cancer Res 1-25
-
(1997)
Adv Cancer Res
, pp. 1-25
-
-
Morgan, S.E.1
Kastan, M.B.2
-
47
-
-
0030485536
-
The dual role of mutant p53 protein in chemosensitivity of human cancers
-
Müller H, Eppenberger U (1996) The dual role of mutant p53 protein in chemosensitivity of human cancers. Anticancer Res 16:3845-3848
-
(1996)
Anticancer Res
, vol.16
, pp. 3845-3848
-
-
Müller, H.1
Eppenberger, U.2
-
48
-
-
0040419494
-
Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/ Fas) receptor/ligand system and involves activation of wild-type p53
-
Müller M, Strand S, Hug H, Heinemann EM, Walczak H, Hofmann WJ, Stremmel W, Krammer PH, Galle PR (1997) Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/ Fas) receptor/ligand system and involves activation of wild-type p53. J Clin Invest 99:403-413
-
(1997)
J Clin Invest
, vol.99
, pp. 403-413
-
-
Müller, M.1
Strand, S.2
Hug, H.3
Heinemann, E.M.4
Walczak, H.5
Hofmann, W.J.6
Stremmel, W.7
Krammer, P.H.8
Galle, P.R.9
-
49
-
-
0029835487
-
Gene therapy for lung cancer: Enhancement of tumor suppression by a combination of sequential systemic cisplatin and adenovirus-mediated p53 gene transfer
-
Nguyen DM, Spitz FR, Yen N, Cristiano RJ, Roth JA (1996) Gene therapy for lung cancer: enhancement of tumor suppression by a combination of sequential systemic cisplatin and adenovirus-mediated p53 gene transfer. J Thorac Cardiovasc Surg 112:1372-1377
-
(1996)
J Thorac Cardiovasc Surg
, vol.112
, pp. 1372-1377
-
-
Nguyen, D.M.1
Spitz, F.R.2
Yen, N.3
Cristiano, R.J.4
Roth, J.A.5
-
50
-
-
0029003501
-
Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression
-
Owen-Schaub LB, Zhang W, Cusack JC, Angelo LS, Santee SM, Fujiwara T, Roth JA, Deisseroth AB, Zhang WW, Kruzel E, Radinsky R (1995) Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression. Mol Cell Biol 15: 3032-3040
-
(1995)
Mol Cell Biol
, vol.15
, pp. 3032-3040
-
-
Owen-Schaub, L.B.1
Zhang, W.2
Cusack, J.C.3
Angelo, L.S.4
Santee, S.M.5
Fujiwara, T.6
Roth, J.A.7
Deisseroth, A.B.8
Zhang, W.W.9
Kruzel, E.10
Radinsky, R.11
-
51
-
-
0030453230
-
p53 and PCNA expression in advanced colorectal cancer: Response to chemotherapy and long-term prognosis
-
Paradiso A, Rabinovich M, Vallejo C, Machiavelli M, Romero A, Perez J, Lacava J, Cuevas MA, Rodriquez R, Leone B, Sapia MG, Simone G, De Lena M (1996) p53 and PCNA expression in advanced colorectal cancer: response to chemotherapy and long-term prognosis. Int J Cancer 69:437-441
-
(1996)
Int J Cancer
, vol.69
, pp. 437-441
-
-
Paradiso, A.1
Rabinovich, M.2
Vallejo, C.3
Machiavelli, M.4
Romero, A.5
Perez, J.6
Lacava, J.7
Cuevas, M.A.8
Rodriquez, R.9
Leone, B.10
Sapia, M.G.11
Simone, G.12
De Lena, M.13
-
52
-
-
8944263468
-
Association between cisplatin resistance and mutation of p53 gene and reduced bax expression in ovarian carcinoma cell systems
-
Perego P, Giarolo M, Righetti SC, Supino R, Caserini C, Delia D, Pierotti MA, Miyashita T, Reed JC, Zunino F (1996) Association between cisplatin resistance and mutation of p53 gene and reduced bax expression in ovarian carcinoma cell systems. Cancer Res 56:556-562
-
(1996)
Cancer Res
, vol.56
, pp. 556-562
-
-
Perego, P.1
Giarolo, M.2
Righetti, S.C.3
Supino, R.4
Caserini, C.5
Delia, D.6
Pierotti, M.A.7
Miyashita, T.8
Reed, J.C.9
Zunino, F.10
-
53
-
-
0028365987
-
Expression of the p53 tumour suppressor gene product is a determinant of chemosensitivity
-
Petty RD, Cree IA, Sutherland LA, Hunter EM, Lande DP, Preece PE, Andreotti PE (1994) Expression of the p53 tumour suppressor gene product is a determinant of chemosensitivity. Biochem Biophys Res Commun 199:264-270
-
(1994)
Biochem Biophys Res Commun
, vol.199
, pp. 264-270
-
-
Petty, R.D.1
Cree, I.A.2
Sutherland, L.A.3
Hunter, E.M.4
Lande, D.P.5
Preece, P.E.6
Andreotti, P.E.7
-
54
-
-
0030969022
-
p53 mediated sensitization of squamous all carcinoma of the head and neck to radiotherapy
-
Pirollo KF, Hao Z, Rait A, Jang YJ, Fee WE, Ryan P, Chiang Y, Chang EH (1997) p53 mediated sensitization of squamous all carcinoma of the head and neck to radiotherapy. Oncogene 14:1735-1746
-
(1997)
Oncogene
, vol.14
, pp. 1735-1746
-
-
Pirollo, K.F.1
Hao, Z.2
Rait, A.3
Jang, Y.J.4
Fee, W.E.5
Ryan, P.6
Chiang, Y.7
Chang, E.H.8
-
55
-
-
7144255569
-
p53 gene transfer in human malignant glioma: Effects on susceptibility to apoptosis
-
Ulm, 1997
-
Pohl U, Trepel M, Naumann U, Dichgans J, Weller M (1997) p53 gene transfer in human malignant glioma: effects on susceptibility to apoptosis (abstract). 6. Arbeitstagung der Deutschen Arbeitsgemeinschaft für Gentherapie. Ulm, 1997
-
(1997)
Arbeitstagung der Deutschen Arbeitsgemeinschaft für Gentherapie
, vol.6
-
-
Pohl, U.1
Trepel, M.2
Naumann, U.3
Dichgans, J.4
Weller, M.5
-
56
-
-
13344249778
-
A comparative study of p53 gene mutations, protein accumulation, and response to cisplatin-based chemotherapy in advanced ovarian carcinoma
-
Righetti SC, Della Torre G, Pilotti S, Ménard S, Ottone F, Colnaghi MI, Pierotti MA, Lavarino C, Cornarotti M, Oriana S, Böhm S, Bresciani GL, Spatti G, Zunino F (1996) A comparative study of p53 gene mutations, protein accumulation, and response to cisplatin-based chemotherapy in advanced ovarian carcinoma. Cancer Res 56:689-693
-
(1996)
Cancer Res
, vol.56
, pp. 689-693
-
-
Righetti, S.C.1
Della Torre, G.2
Pilotti, S.3
Ménard, S.4
Ottone, F.5
Colnaghi, M.I.6
Pierotti, M.A.7
Lavarino, C.8
Cornarotti, M.9
Oriana, S.10
Böhm, S.11
Bresciani, G.L.12
Spatti, G.13
Zunino, F.14
-
57
-
-
0030896574
-
Immunochemotherapy of malignant glioma: Synergistic activity of CD95 ligand and chemotherapeutics
-
Roth W, Fontana A, Trepel M, Dichgans J, Reed JC, Weller M (1997a) Immunochemotherapy of malignant glioma: synergistic activity of CD95 ligand and chemotherapeutics. Cancer Immunol Immunother 44:55-63
-
(1997)
Cancer Immunol Immunother
, vol.44
, pp. 55-63
-
-
Roth, W.1
Fontana, A.2
Trepel, M.3
Dichgans, J.4
Reed, J.C.5
Weller, M.6
-
58
-
-
7144256289
-
Taxol-mediated augmentation of CD95 ligand-induced apoptosis of human malignant glioma cells is independent of p53 induction and G2/M cell cycle arrest
-
in press
-
Roth W, Wagenknecht B, Grimmel C, Dichgans J, Weller M (1997b) Taxol-mediated augmentation of CD95 ligand-induced apoptosis of human malignant glioma cells is independent of p53 induction and G2/M cell cycle arrest. Br J Cancer (in press)
-
(1997)
Br J Cancer
-
-
Roth, W.1
Wagenknecht, B.2
Grimmel, C.3
Dichgans, J.4
Weller, M.5
-
59
-
-
0028840535
-
Aberrant p53 expression predicts clinical resistance to cisplatin-based chemotherapy in locally advanced non-small cell lung cancer
-
Rusch V, Klimstra D, Venkatraman E, Oliver J, Martini N, Gralla R, Kris M, Dmitrovsky E (1995) Aberrant p53 expression predicts clinical resistance to cisplatin-based chemotherapy in locally advanced non-small cell lung cancer. Cancer Res 55:5038-5042
-
(1995)
Cancer Res
, vol.55
, pp. 5038-5042
-
-
Rusch, V.1
Klimstra, D.2
Venkatraman, E.3
Oliver, J.4
Martini, N.5
Gralla, R.6
Kris, M.7
Dmitrovsky, E.8
-
60
-
-
0030045087
-
Relationship between p53 status and radiosensitivity in human tumour cell lines
-
Siles E, Villalobos M, Valenzuela MT, Núñez MI, Gordon A, McMillan TJ, Pedraza V, Ruiz de Almodóvar JM (1996) Relationship between p53 status and radiosensitivity in human tumour cell lines. Br J Cancer 73:581-588
-
(1996)
Br J Cancer
, vol.73
, pp. 581-588
-
-
Siles, E.1
Villalobos, M.2
Valenzuela, M.T.3
Núñez, M.I.4
Gordon, A.5
McMillan, T.J.6
Pedraza, V.7
Ruiz De Almodóvar, J.M.8
-
61
-
-
0031029576
-
Expression of wild-type p53 increases etoposide cytotoxicity in M1 myeloid leukemia cells by facilitated GT to M transition: Implications for gene therapy
-
Skladanowski A, Larsen AK (1997) Expression of wild-type p53 increases etoposide cytotoxicity in M1 myeloid leukemia cells by facilitated GT to M transition: implications for gene therapy. Cancer Res 57:818-823
-
(1997)
Cancer Res
, vol.57
, pp. 818-823
-
-
Skladanowski, A.1
Larsen, A.K.2
-
62
-
-
0027893001
-
Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNa damage
-
Slichenmyer WJ, Nelson WG, Slebos RJ, Kastan MB (1993) Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage. Cancer Res 53:4164-4168
-
(1993)
Cancer Res
, vol.53
, pp. 4164-4168
-
-
Slichenmyer, W.J.1
Nelson, W.G.2
Slebos, R.J.3
Kastan, M.B.4
-
63
-
-
0030722470
-
A new look at the role of p53 in leukemia cell sensitivity to chemotherapy
-
Trepel M, Scheding S, Groscurth P, Horny HP, Malipiero U, Brugger W, Dichgans J, Weller M (1997) A new look at the role of p53 in leukemia cell sensitivity to chemotherapy. Leukemia 11:1842-1849
-
(1997)
Leukemia
, vol.11
, pp. 1842-1849
-
-
Trepel, M.1
Scheding, S.2
Groscurth, P.3
Horny, H.P.4
Malipiero, U.5
Brugger, W.6
Dichgans, J.7
Weller, M.8
-
64
-
-
0031689575
-
Chemosensitivity of human malignant glioma: Modulation by p53 gene transfer
-
in press
-
Trepel M, Groscurth P, Malipiero U, Gulbins E, Dichgans J, Weller M (1998) Chemosensitivity of human malignant glioma: modulation by p53 gene transfer. J Neurooncol (in press)
-
(1998)
J Neurooncol
-
-
Trepel, M.1
Groscurth, P.2
Malipiero, U.3
Gulbins, E.4
Dichgans, J.5
Weller, M.6
-
65
-
-
0029054581
-
Abrogation of p53 function by transfection of HPV 16 E6 gene enhances the resistance of human diploid fibroblasts to ionizing radiation
-
Tsang NM, Nagasawa H, Li C, Little JB (1995) Abrogation of p53 function by transfection of HPV 16 E6 gene enhances the resistance of human diploid fibroblasts to ionizing radiation. Oncogene 10:2403-2408
-
(1995)
Oncogene
, vol.10
, pp. 2403-2408
-
-
Tsang, N.M.1
Nagasawa, H.2
Li, C.3
Little, J.B.4
-
66
-
-
0030465009
-
Cisplatin, camptothecin, and taxol sensitivities of cells with p53-associated multidrug resistance
-
Vasey PA, Jones NA, Jenkins S, Dive C, Brown R (1996) Cisplatin, camptothecin, and taxol sensitivities of cells with p53-associated multidrug resistance. Mol Pharmacol 50:1536-1540
-
(1996)
Mol Pharmacol
, vol.50
, pp. 1536-1540
-
-
Vasey, P.A.1
Jones, N.A.2
Jenkins, S.3
Dive, C.4
Brown, R.5
-
67
-
-
0028916558
-
Decreased cytotoxic effects of doxorubicin in a human ovarian cancer-cell line expressing wild-type p53 and WAF/CIP1 genes
-
Vikhanskaya F, D'Incalci M, Broggini M (1995) Decreased cytotoxic effects of doxorubicin in a human ovarian cancer-cell line expressing wild-type p53 and WAF/CIP1 genes. Int J Cancer 61:397-401
-
(1995)
Int J Cancer
, vol.61
, pp. 397-401
-
-
Vikhanskaya, F.1
D'Incalci, M.2
Broggini, M.3
-
68
-
-
0027361941
-
Analysis of p53 mutations in a large series of lymphoid hematologic malignancies of childhood
-
Wada M, Bartram CR, Nakamura H, Hachiya M, Chen DL, Borenstein J, Miller CW, Ludwig L, Hansen-Hagge TE, Ludwig WD, Reiter A, Mizoguchi H, Koeffler HP (1993) Analysis of p53 mutations in a large series of lymphoid hematologic malignancies of childhood. Blood 82:3163-3169
-
(1993)
Blood
, vol.82
, pp. 3163-3169
-
-
Wada, M.1
Bartram, C.R.2
Nakamura, H.3
Hachiya, M.4
Chen, D.L.5
Borenstein, J.6
Miller, C.W.7
Ludwig, L.8
Hansen-Hagge, T.E.9
Ludwig, W.D.10
Reiter, A.11
Mizoguchi, H.12
Koeffler, H.P.13
-
69
-
-
0030656196
-
p53 accumulation promotes dephosphorylation and proteolytic cleavage of retinoblastoma protein in human malignant glioma cells
-
Wagenknecht B, Trepel M, Von Deimling A, Grimmel C, Rollbrocker B, Hayashi Y, Lang F, Dichgans J, Gulbins J, Weller M (1997) p53 accumulation promotes dephosphorylation and proteolytic cleavage of retinoblastoma protein in human malignant glioma cells. Cell Physiol Biochem 7:304-311
-
(1997)
Cell Physiol Biochem
, vol.7
, pp. 304-311
-
-
Wagenknecht, B.1
Trepel, M.2
Von Deimling, A.3
Grimmel, C.4
Rollbrocker, B.5
Hayashi, Y.6
Lang, F.7
Dichgans, J.8
Gulbins, J.9
Weller, M.10
-
70
-
-
0030026934
-
Loss of normal p53 function confers sensitization to taxol by increasing G2/M arrest and apoptosis
-
Wahl AF, Donaldson KL, Fairchild C, Lee FYF, Foster SA, Demers GW, Galloway DA (1996) Loss of normal p53 function confers sensitization to taxol by increasing G2/M arrest and apoptosis. Nat Med 2:72-79
-
(1996)
Nat Med
, vol.2
, pp. 72-79
-
-
Wahl, A.F.1
Donaldson, K.L.2
Fairchild, C.3
Lee, F.Y.F.4
Foster, S.A.5
Demers, G.W.6
Galloway, D.A.7
-
71
-
-
0030442972
-
TP53 tumour suppressor gene: Clues to molecular carcinogenesis and cancer therapy
-
Wang XW, Harris CC (1996) TP53 tumour suppressor gene: clues to molecular carcinogenesis and cancer therapy. Cancer Surv 28:169-196
-
(1996)
Cancer Surv
, vol.28
, pp. 169-196
-
-
Wang, X.W.1
Harris, C.C.2
-
72
-
-
0001166257
-
The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathways
-
Wang XW, Vermeulen W, Coursen JD, Gibson M, Lupold SE, Forrester K, Xu G, Elmore L, Yeh H, Hoeijmakers JHJ, Harris CC (1996) The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathways. Genes Dev 10:1219-1232
-
(1996)
Genes Dev
, vol.10
, pp. 1219-1232
-
-
Wang, X.W.1
Vermeulen, W.2
Coursen, J.D.3
Gibson, M.4
Lupold, S.E.5
Forrester, K.6
Xu, G.7
Elmore, L.8
Yeh, H.9
Hoeijmakers, J.H.J.10
Harris, C.C.11
-
73
-
-
0031018994
-
Relationship of p53, bcl-2, and tumor proliferation to clinical drug resistance in non-Hodgkin's lymphomas
-
Wilson WH, Teruya-Feldstein J, Fest T, Harris C, Steinberg SM, Jaffe ES, Raffeid M (1997) Relationship of p53, bcl-2, and tumor proliferation to clinical drug resistance in non-Hodgkin's lymphomas. Blood 89:601-609
-
(1997)
Blood
, vol.89
, pp. 601-609
-
-
Wilson, W.H.1
Teruya-Feldstein, J.2
Fest, T.3
Harris, C.4
Steinberg, S.M.5
Jaffe, E.S.6
Raffeid, M.7
-
74
-
-
7144229412
-
Synergistic activity of CD95 ligand and teniposide (VM26) does not involve enhanced formation of cleavable DNA complexes or changes in CD95/CD95 ligand expression
-
in press
-
Winter S, Roth W, Dichgans J, Weller M (1997) Synergistic activity of CD95 ligand and teniposide (VM26) does not involve enhanced formation of cleavable DNA complexes or changes in CD95/CD95 ligand expression. Eur J Pharmacol (in press)
-
(1997)
Eur J Pharmacol
-
-
Winter, S.1
Roth, W.2
Dichgans, J.3
Weller, M.4
-
75
-
-
0030094571
-
p53 and chemosensitivity
-
Wu GS, El-Deiry WS (1996) p53 and chemosensitivity. Nat Med 2:255-256
-
(1996)
Nat Med
, vol.2
, pp. 255-256
-
-
Wu, G.S.1
El-Deiry, W.S.2
|