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Volumn 6, Issue 1, 2003, Pages 27-39

Tumor p53 status and response to topoisomerase II inhibitors

Author keywords

Anticancer drugs; Apoptosis; Drug resistance; p53; Topoisomerase II

Indexed keywords

ANTINEOPLASTIC AGENT; DNA TOPOISOMERASE (ATP HYDROLYSING); GYRASE INHIBITOR; HISTONE DEACETYLASE; PROTEIN P53; TUMOR SUPPRESSOR PROTEIN;

EID: 0037303999     PISSN: 13687646     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1368-7646(02)00143-7     Document Type: Review
Times cited : (31)

References (154)
  • 2
    • 0036490207 scopus 로고    scopus 로고
    • A nucleotide excision repair master-switch: p53 regulated coordinate induction of global genomic repair genes
    • Amundson, S.A., Patterson, A., Do, K.T., Fornace, Jr., A.J., 2002. A nucleotide excision repair master-switch: p53 regulated coordinate induction of global genomic repair genes. Cancer Biol. Ther. 1, 145-149.
    • (2002) Cancer Biol. Ther. , vol.1 , pp. 145-149
    • Amundson, S.A.1    Patterson, A.2    Do, K.T.3    Fornace A.J., Jr.4
  • 3
    • 0035837406 scopus 로고    scopus 로고
    • p53-interacting protein 53BP2 inhibits clonogenic survival and sensitizes cells to doxorubicin but not paclitaxel-induced apoptosis
    • Ao, Y., Rohde, L.H., Naumovski, L., 2001. p53-interacting protein 53BP2 inhibits clonogenic survival and sensitizes cells to doxorubicin but not paclitaxel-induced apoptosis. Oncogene 20, 2720-2725.
    • (2001) Oncogene , vol.20 , pp. 2720-2725
    • Ao, Y.1    Rohde, L.H.2    Naumovski, L.3
  • 4
    • 0033611413 scopus 로고    scopus 로고
    • Differential regulation of p21 waf-1/cip-1 and Mdm2 by etoposide: Etoposide inhibits the p53-Mdm2 autoregulatory feedback loop
    • Arriola, E.L., Lopez, A.R., Chresta, C.M., 1999. Differential regulation of p21 waf-1/cip-1 and Mdm2 by etoposide: etoposide inhibits the p53-Mdm2 autoregulatory feedback loop. Oncogene 18, 1081-1091.
    • (1999) Oncogene , vol.18 , pp. 1081-1091
    • Arriola, E.L.1    Lopez, A.R.2    Chresta, C.M.3
  • 5
    • 0034850266 scopus 로고    scopus 로고
    • Exonucleolytic proofreading by p53 protein
    • Bakhanashvili, M., 2001. Exonucleolytic proofreading by p53 protein. Eur. J. Biochem. 268, 2047-2054.
    • (2001) Eur. J. Biochem. , vol.268 , pp. 2047-2054
    • Bakhanashvili, M.1
  • 6
    • 0035731631 scopus 로고    scopus 로고
    • p53, bcl-2 and bax immunoreactivity as predictors of response and outcome after chemotherapy for metastatic germ cell testicular tumours
    • Baltaci, S., Orhan, D., Turkolmez, K., Yesilli, C., Beduk, Y., Tulunay, O., 2001. p53, bcl-2 and bax immunoreactivity as predictors of response and outcome after chemotherapy for metastatic germ cell testicular tumours. BJU Int. 87, 661-666.
    • (2001) BJU Int. , vol.87 , pp. 661-666
    • Baltaci, S.1    Orhan, D.2    Turkolmez, K.3    Yesilli, C.4    Beduk, Y.5    Tulunay, O.6
  • 7
    • 0037012041 scopus 로고    scopus 로고
    • The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells
    • Baptiste, N., Friedlander, P., Chen, X., Prives, C., 2002. The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells. Oncogene 21, 9-21.
    • (2002) Oncogene , vol.21 , pp. 9-21
    • Baptiste, N.1    Friedlander, P.2    Chen, X.3    Prives, C.4
  • 8
    • 0037138454 scopus 로고    scopus 로고
    • Pifithrin-α, an inhibitor of p53, enhances the genetic instability induced by etoposide (VP-16) in human lymphoblastoid cells treated in vitro
    • Bassi, L., Carloni, M., Fonti, E., Palma de la Peña, N., Meschini, R., Palitti, F., 2002. Pifithrin-α, an inhibitor of p53, enhances the genetic instability induced by etoposide (VP-16) in human lymphoblastoid cells treated in vitro. Mutat. Res. 499, 163-176.
    • (2002) Mutat. Res. , vol.499 , pp. 163-176
    • Bassi, L.1    Carloni, M.2    Fonti, E.3    Palma de la Peña, N.4    Meschini, R.5    Palitti, F.6
  • 9
    • 0033502716 scopus 로고    scopus 로고
    • Tumor cell resistance to DNA topoisomerase II inhibitors: New developments
    • Beck, W.T., Morgan, S.E., Mo, Y.-Y., Bhat, U.G., 1999. Tumor cell resistance to DNA topoisomerase II inhibitors: new developments. Drug Resist. Updates 2, 382-389.
    • (1999) Drug Resist. Updates , vol.2 , pp. 382-389
    • Beck, W.T.1    Morgan, S.E.2    Mo, Y.-Y.3    Bhat, U.G.4
  • 11
    • 0033543661 scopus 로고    scopus 로고
    • Using a biochemical approach to identify the primary dimerization regions in human DNA topoisomerase II alpha
    • Bjergbaek, L., Jensen, S., Westergaard, O., Andersen, A.H., 1999. Using a biochemical approach to identify the primary dimerization regions in human DNA topoisomerase II alpha. J. Biol. Chem. 274, 26529-26536.
    • (1999) J. Biol. Chem. , vol.274 , pp. 26529-26536
    • Bjergbaek, L.1    Jensen, S.2    Westergaard, O.3    Andersen, A.H.4
  • 13
    • 0034935347 scopus 로고    scopus 로고
    • Does resistance to apoptosis affect clinical response to antitumor drugs?
    • Borst, P., Borst, J., Smets, L.A., 2001. Does resistance to apoptosis affect clinical response to antitumor drugs? Drug Resist. Updates 4, 129-137.
    • (2001) Drug Resist. Updates , vol.4 , pp. 129-137
    • Borst, P.1    Borst, J.2    Smets, L.A.3
  • 14
    • 0037157850 scopus 로고    scopus 로고
    • Scotin, a novel p53-inducible proapoptotic protein located in the ER and the nuclear membrane
    • Bourdon, J.-C., Renzing, J., Robertson, P.L., Fernandes, K.N., Lane, D.P., 2002. Scotin, a novel p53-inducible proapoptotic protein located in the ER and the nuclear membrane. J. Cell Biol. 158, 235-246.
    • (2002) J. Cell Biol. , vol.158 , pp. 235-246
    • Bourdon, J.-C.1    Renzing, J.2    Robertson, P.L.3    Fernandes, K.N.4    Lane, D.P.5
  • 15
    • 0036248532 scopus 로고    scopus 로고
    • Transcriptional regulation of the human topoisomerase II alpha gene
    • Bronner, C., Hopfner, R., Mousli, M., 2002. Transcriptional regulation of the human topoisomerase II alpha gene. Anticancer Res. 22, 605-612.
    • (2002) Anticancer Res. , vol.22 , pp. 605-612
    • Bronner, C.1    Hopfner, R.2    Mousli, M.3
  • 16
    • 0033118475 scopus 로고    scopus 로고
    • Apoptosis, p53, and tumor cell sensitivity to anticancer agents
    • Brown, J.M., Wouters, B.G., 1999. Apoptosis, p53, and tumor cell sensitivity to anticancer agents. Cancer Res. 59, 1391-1399.
    • (1999) Cancer Res. , vol.59 , pp. 1391-1399
    • Brown, J.M.1    Wouters, B.G.2
  • 17
    • 0034931001 scopus 로고    scopus 로고
    • Apoptosis: Mediator or mode of cell killing by anticancer agents?
    • Brown, J.M., Wouters, B.G., 2001. Apoptosis: mediator or mode of cell killing by anticancer agents? Drug Resist. Updates 4, 135-136.
    • (2001) Drug Resist. Updates , vol.4 , pp. 135-136
    • Brown, J.M.1    Wouters, B.G.2
  • 18
    • 0035177001 scopus 로고    scopus 로고
    • Cancer research 2001: Drug resistance, new targets and drug combinations
    • Broxterman, H.J., Georgopapadakou, N., 2001. Cancer research 2001: drug resistance, new targets and drug combinations. Drug Resist. Updates 4, 197-209.
    • (2001) Drug Resist. Updates , vol.4 , pp. 197-209
    • Broxterman, H.J.1    Georgopapadakou, N.2
  • 20
    • 0028670198 scopus 로고
    • Phosphorylation of the α- and β-isoforms of DNA topoisomerase II is qualitatively different in interphase and mitosis in Chinese hamster ovary cells
    • Burden, D.A., Sullivan, D.M., 1994. Phosphorylation of the α- and β-isoforms of DNA topoisomerase II is qualitatively different in interphase and mitosis in Chinese hamster ovary cells. Biochemistry 33, 14651-14655.
    • (1994) Biochemistry , vol.33 , pp. 14651-14655
    • Burden, D.A.1    Sullivan, D.M.2
  • 22
    • 0036296164 scopus 로고    scopus 로고
    • The ATP-operated clamp of human DNA topoisomerase IIalpha: Hyperstimulation of ATPase by piggy-back binding
    • Campbell, S., Maxwell, A., 2002. The ATP-operated clamp of human DNA topoisomerase IIalpha: hyperstimulation of ATPase by piggy-back binding. J. Mol. Biol. 320, 171-188.
    • (2002) J. Mol. Biol. , vol.320 , pp. 171-188
    • Campbell, S.1    Maxwell, A.2
  • 23
    • 0026607164 scopus 로고
    • Casein kinase II phosphorylates the eukaryote-specific C-terminal domain of topoisomerase II in vivo
    • Cardenas, M.E., Dang, Q., Glover, C., Gasser, S.M., 1992. Casein kinase II phosphorylates the eukaryote-specific C-terminal domain of topoisomerase II in vivo. EMBO J. 11, 1785-1796.
    • (1992) EMBO J. , vol.11 , pp. 1785-1796
    • Cardenas, M.E.1    Dang, Q.2    Glover, C.3    Gasser, S.M.4
  • 24
    • 0034991321 scopus 로고    scopus 로고
    • Evaluation of HER2, p53, bcl-2, topoisomerase II-alpha, heat shock proteins 27 and 70 in primary breast cancer and metastatic ipsilateral axillary lymph nodes
    • Cardoso, F., Di Leo, A., Larismont, D., Gancberg, D., Rouas, G., Dolci, S., Ferreira, F., Paesmans, M., Piccart, M., 2001. Evaluation of HER2, p53, bcl-2, topoisomerase II-alpha, heat shock proteins 27 and 70 in primary breast cancer and metastatic ipsilateral axillary lymph nodes. Ann. Oncol. 12, 615-620.
    • (2001) Ann. Oncol. , vol.12 , pp. 615-620
    • Cardoso, F.1    Di Leo, A.2    Larismont, D.3    Gancberg, D.4    Rouas, G.5    Dolci, S.6    Ferreira, F.7    Paesmans, M.8    Piccart, M.9
  • 25
    • 0032211353 scopus 로고    scopus 로고
    • Expression of p53 protein and resistance to preoperative chemotherapy in locally advanced gastric carcinoma
    • Cascinu, S., Graziano, F., Del Ferro, E., Staccioli, M.P., Ligi, M., Carnevali, A., Muretto, P., Catalano, G., 1998. Expression of p53 protein and resistance to preoperative chemotherapy in locally advanced gastric carcinoma. Cancer 83, 1917-1922.
    • (1998) Cancer , vol.83 , pp. 1917-1922
    • Cascinu, S.1    Graziano, F.2    Del Ferro, E.3    Staccioli, M.P.4    Ligi, M.5    Carnevali, A.6    Muretto, P.7    Catalano, G.8
  • 26
  • 27
    • 0034978219 scopus 로고    scopus 로고
    • Various forms of mutant p53 confer sensitivity to cisplatin and doxorubicin in bladder cancer cells
    • Chang, F.L., Lai, M.D., 2001. Various forms of mutant p53 confer sensitivity to cisplatin and doxorubicin in bladder cancer cells. J. Urol. 166, 304-310.
    • (2001) J. Urol. , vol.166 , pp. 304-310
    • Chang, F.L.1    Lai, M.D.2
  • 28
    • 0035013497 scopus 로고    scopus 로고
    • Immunohistochemical staining for DNA topoisomerase I, DNA topoisomerase II-alpha and p53 in gastric carcinomas
    • Coleman, L.W., Bronstein, I.B., Holden, J.A., 2001. Immunohistochemical staining for DNA topoisomerase I, DNA topoisomerase II-alpha and p53 in gastric carcinomas. Anticancer Res. 21, 1167-1172.
    • (2001) Anticancer Res. , vol.21 , pp. 1167-1172
    • Coleman, L.W.1    Bronstein, I.B.2    Holden, J.A.3
  • 31
    • 0034815639 scopus 로고    scopus 로고
    • Repression of cyclin B1 expression after treatment with adriamycin, but not cisplatin in human lung cancer A549 cells
    • Dan, S., Yamori, T., 2001. Repression of cyclin B1 expression after treatment with adriamycin, but not cisplatin in human lung cancer A549 cells. Biochem. Biophys. Res. Commun. 280, 861-867.
    • (2001) Biochem. Biophys. Res. Commun. , vol.280 , pp. 861-867
    • Dan, S.1    Yamori, T.2
  • 32
    • 0032550174 scopus 로고    scopus 로고
    • The genomic sequences bound to special AT-rich sequence-binding protein 1 (SATB1) in vivo in Jurkat T cells are tightly associated with the nuclear matrix at the bases of the chromatin loops
    • de Belle, I., Cai, S., Kohwi-Shigematsu, T., 1998. The genomic sequences bound to special AT-rich sequence-binding protein 1 (SATB1) in vivo in Jurkat T cells are tightly associated with the nuclear matrix at the bases of the chromatin loops. J. Cell Biol. 141, 335-348.
    • (1998) J. Cell Biol. , vol.141 , pp. 335-348
    • De Belle, I.1    Cai, S.2    Kohwi-Shigematsu, T.3
  • 34
    • 0032771490 scopus 로고    scopus 로고
    • Expression of DNA topoisomerase IIα and topoisomerase IIβ genes predicts survival and response to chemotherapy in patients with small cell lung cancer
    • Dingemans, A.-M.C., Witlox, M.A., Stallaert, R.A.L.M., van der Valk, P., Postmus, P.E., Giaccone, G., 1999. Expression of DNA topoisomerase IIα and topoisomerase IIβ genes predicts survival and response to chemotherapy in patients with small cell lung cancer. Clin. Cancer Res. 5, 2048-2058.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 2048-2058
    • Dingemans, A.-M.C.1    Witlox, M.A.2    Stallaert, R.A.L.M.3    Van der Valk, P.4    Postmus, P.E.5    Giaccone, G.6
  • 36
    • 0035914432 scopus 로고    scopus 로고
    • Caffeine sensitizes human H358 cell line to p53-mediated apoptosis by inducing mitochondrial translocation and conformational change of BAX protein
    • Dubrez, L., Coll, J.-L., Hurbin, A., Solary, E., Favrot, M.-C., 2001. Caffeine sensitizes human H358 cell line to p53-mediated apoptosis by inducing mitochondrial translocation and conformational change of BAX protein. J. Biol. Chem. 276, 38980-38987.
    • (2001) J. Biol. Chem. , vol.276 , pp. 38980-38987
    • Dubrez, L.1    Coll, J.-L.2    Hurbin, A.3    Solary, E.4    Favrot, M.-C.5
  • 37
    • 0031865231 scopus 로고    scopus 로고
    • Specific mismatch recognition in heteroduplex intermediates suggests a role in fidelity control of homologous recombination
    • Dudenhoffer, C., Rohaly, G., Will, K., Deppert, W., Weismuller, L., 1998. Specific mismatch recognition in heteroduplex intermediates suggests a role in fidelity control of homologous recombination. Mol. Cell. Biol. 18, 5332-5342.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 5332-5342
    • Dudenhoffer, C.1    Rohaly, G.2    Will, K.3    Deppert, W.4    Weismuller, L.5
  • 39
    • 0037152679 scopus 로고    scopus 로고
    • Increased sensitivity of p53-deficient cells to anticancer agents due to loss of pms2
    • Fedier, A., Ruefenacht, U.B., Schwartz, V.A., Haller, U., Fink, D., 2002. Increased sensitivity of p53-deficient cells to anticancer agents due to loss of pms2. Br. J. Cancer 87, 1027-1033.
    • (2002) Br. J. Cancer , vol.87 , pp. 1027-1033
    • Fedier, A.1    Ruefenacht, U.B.2    Schwartz, V.A.3    Haller, U.4    Fink, D.5
  • 40
    • 0032189081 scopus 로고    scopus 로고
    • Secondary leukemias induced by topoisomerase-targeted drugs
    • Felix, C.A., 1998. Secondary leukemias induced by topoisomerase-targeted drugs. Biochim. Biophys. Acta 1400, 233-255.
    • (1998) Biochim. Biophys. Acta , vol.1400 , pp. 233-255
    • Felix, C.A.1
  • 41
    • 0036815597 scopus 로고    scopus 로고
    • P53 as a therapeutic target: Unresolved issues on the road to cancer therapy targeting mutant p53
    • Fojo, T., 2002. P53 as a therapeutic target: unresolved issues on the road to cancer therapy targeting mutant p53. Drug Resist. Updates 5, 209-216.
    • (2002) Drug Resist. Updates , vol.5 , pp. 209-216
    • Fojo, T.1
  • 42
    • 0033601370 scopus 로고    scopus 로고
    • Pharmacological rescue of mutant p53 conformation and function
    • Foster, B.A., Coffey, H.A., Morin, M.J., Rastinejad, F., 1999. Pharmacological rescue of mutant p53 conformation and function. Science 286, 2507-2510.
    • (1999) Science , vol.286 , pp. 2507-2510
    • Foster, B.A.1    Coffey, H.A.2    Morin, M.J.3    Rastinejad, F.4
  • 43
    • 0036343777 scopus 로고    scopus 로고
    • Expression of different mutant p53 transgenes in neuroblastoma cells leads to different cellular responses to genotoxic agents
    • Gangopadhyay, S., Jalali, F., Reda, D., Peacock, J., Bristow, R.G., Benchimol, S., 2002. Expression of different mutant p53 transgenes in neuroblastoma cells leads to different cellular responses to genotoxic agents. Exp. Cell Res. 275, 122-131.
    • (2002) Exp. Cell Res. , vol.275 , pp. 122-131
    • Gangopadhyay, S.1    Jalali, F.2    Reda, D.3    Peacock, J.4    Bristow, R.G.5    Benchimol, S.6
  • 44
    • 0033621189 scopus 로고    scopus 로고
    • The interaction between p53 and DNA topoisomerase I is regulated differently in cells with wild-type and mutant p53
    • Gobert, C., Skladanowski, A., Larsen, A.K., 1999. The interaction between p53 and DNA topoisomerase I is regulated differently in cells with wild-type and mutant p53. Proc. Natl. Acad. Sci. U.S.A. 96, 10355-10360.
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 10355-10360
    • Gobert, C.1    Skladanowski, A.2    Larsen, A.K.3
  • 45
    • 0037174933 scopus 로고    scopus 로고
    • Specific interaction of p53 with target binding sites is determined by DNA conformation and is regulated by the C-terminal domain
    • Gohler, T., Reimann, M., Cherny, D., Walter, K., Warnecke, G., Kim, E., Deppert, W., 2002. Specific interaction of p53 with target binding sites is determined by DNA conformation and is regulated by the C-terminal domain. J. Biol. Chem. 277, 41192-41203.
    • (2002) J. Biol. Chem. , vol.277 , pp. 41192-41203
    • Gohler, T.1    Reimann, M.2    Cherny, D.3    Walter, K.4    Warnecke, G.5    Kim, E.6    Deppert, W.7
  • 46
    • 0035196861 scopus 로고    scopus 로고
    • Identification of p53 sequence elements that are required for MDM2-mediated nuclear export
    • Gu, J., Nie, L., Wiederschain, D., Yuan, Z.-M., 2001. Identification of p53 sequence elements that are required for MDM2-mediated nuclear export. Mol. Cell. Biol. 21, 8533-8546.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 8533-8546
    • Gu, J.1    Nie, L.2    Wiederschain, D.3    Yuan, Z.-M.4
  • 47
    • 0034855810 scopus 로고    scopus 로고
    • Value of topoisomerase II alpha, MIB-1, p53, E-cadherin, retinoblastoma gene protein product, and HER-2/neu immunohistochemical expression for the prediction of biologic behavior in adrenocortical neoplasms
    • Gupta, D., Shidham, V., Holden, J., Layfield, L., 2001. Value of topoisomerase II alpha, MIB-1, p53, E-cadherin, retinoblastoma gene protein product, and HER-2/neu immunohistochemical expression for the prediction of biologic behavior in adrenocortical neoplasms. Appl. Immunohistochem. Mol. Morphol. 3, 215-221.
    • (2001) Appl. Immunohistochem. Mol. Morphol. , vol.3 , pp. 215-221
    • Gupta, D.1    Shidham, V.2    Holden, J.3    Layfield, L.4
  • 49
    • 0036720637 scopus 로고    scopus 로고
    • Reliable detection of p53 aberations in squamous cell carcinomas of the head and neck requires transcript analysis of the entire coding region
    • Hauser, U., Balz, V., Carey, T.E., Grenman, R., van Lierop, A., Scheckenbach, K., Bier, H., 2002. Reliable detection of p53 aberations in squamous cell carcinomas of the head and neck requires transcript analysis of the entire coding region. Head Neck 24, 868-873.
    • (2002) Head Neck , vol.24 , pp. 868-873
    • Hauser, U.1    Balz, V.2    Carey, T.E.3    Grenman, R.4    Van Lierop, A.5    Scheckenbach, K.6    Bier, H.7
  • 50
    • 0022896243 scopus 로고
    • Topoisomerase II: A specific marker for cell proliferation
    • Heck, M.M., Earnshaw, W.C., 1986. Topoisomerase II: a specific marker for cell proliferation. J. Cell Biol. 103, 2569-2581.
    • (1986) J. Cell Biol. , vol.103 , pp. 2569-2581
    • Heck, M.M.1    Earnshaw, W.C.2
  • 51
    • 0024453524 scopus 로고
    • In vivo phosphorylation of the 170-kDa form of eukaryotic DNA topoisomerase II. Cell cycle analysis
    • Heck, M.M., Hittelman, W.N., Earnshaw, W., 1989. In vivo phosphorylation of the 170-kDa form of eukaryotic DNA topoisomerase II. Cell cycle analysis. J. Biol. Chem. 264, 15161-15164.
    • (1989) J. Biol. Chem. , vol.264 , pp. 15161-15164
    • Heck, M.M.1    Hittelman, W.N.2    Earnshaw, W.3
  • 52
    • 0000266944 scopus 로고
    • Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle
    • Heck, M.M., Hittelman, W.N., Earnshaw, W.C., 1988. Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle. Proc. Natl. Acad. Sci. U.S.A. 85, 1086-1090.
    • (1988) Proc. Natl. Acad. Sci. U.S.A. , vol.85 , pp. 1086-1090
    • Heck, M.M.1    Hittelman, W.N.2    Earnshaw, W.C.3
  • 53
    • 0026648642 scopus 로고
    • Cloning and characterization of the 5′-flanking region of the human topoisomerase IIα gene
    • Hochhauser, D., Stanway, C.A., Harris, A.L., Hickson, I.D., 1992. Cloning and characterization of the 5′-flanking region of the human topoisomerase IIα gene. J. Biol. Chem. 267, 18961-18965.
    • (1992) J. Biol. Chem. , vol.267 , pp. 18961-18965
    • Hochhauser, D.1    Stanway, C.A.2    Harris, A.L.3    Hickson, I.D.4
  • 56
    • 0037020090 scopus 로고    scopus 로고
    • CCAAT binding factor (CBF) binding mediates cell cycle activation of topoisomerase IIα. Conventional CBF activation domains are not required
    • Hu, Q., Bhattacharya, C., Maity, S.N., 2002. CCAAT binding factor (CBF) binding mediates cell cycle activation of topoisomerase IIα. Conventional CBF activation domains are not required. J. Biol. Chem. 277, 37191-37200.
    • (2002) J. Biol. Chem. , vol.277 , pp. 37191-37200
    • Hu, Q.1    Bhattacharya, C.2    Maity, S.N.3
  • 58
    • 0034739331 scopus 로고    scopus 로고
    • Administration of wild-type p53 adenoviral vector synergistically enhances the cytotoxicity of anti-cancer drugs in human lung cancer cells irrespective of the status of p53 gene
    • Inoue, A., Narumi, K., Matsubara, N., Sugawara, A.-i., Saijo, Y., Satoh, K., Nukiwa, T., 2000. Administration of wild-type p53 adenoviral vector synergistically enhances the cytotoxicity of anti-cancer drugs in human lung cancer cells irrespective of the status of p53 gene. Cancer Lett. 157, 105-112.
    • (2000) Cancer Lett. , vol.157 , pp. 105-112
    • Inoue, A.1    Narumi, K.2    Matsubara, N.3    Sugawara, A.-I.4    Saijo, Y.5    Satoh, K.6    Nukiwa, T.7
  • 60
    • 0035418619 scopus 로고    scopus 로고
    • The role of the DNA mismatch repair system in the cytotoxicity of the topoisomerase inhibitors camptothecin and etoposide to human colorectal cancer cells
    • Jacob, S., Aguado, M., Fallik, D., Praz, F., 2001. The role of the DNA mismatch repair system in the cytotoxicity of the topoisomerase inhibitors camptothecin and etoposide to human colorectal cancer cells. Cancer Res. 61, 6555-6562.
    • (2001) Cancer Res. , vol.61 , pp. 6555-6562
    • Jacob, S.1    Aguado, M.2    Fallik, D.3    Praz, F.4
  • 62
    • 0031775808 scopus 로고    scopus 로고
    • Predictive value of topoisomerase II alpha and other prognostic factors for epirubicin chemotherapy in advanced breast cancer
    • Jarvinen, T.A., Holli, K., Kuukasjarvi, T., Isola, J.J., 1998. Predictive value of topoisomerase II alpha and other prognostic factors for epirubicin chemotherapy in advanced breast cancer. Br. J. Cancer 77, 2267-2273.
    • (1998) Br. J. Cancer , vol.77 , pp. 2267-2273
    • Jarvinen, T.A.1    Holli, K.2    Kuukasjarvi, T.3    Isola, J.J.4
  • 64
    • 0037163085 scopus 로고    scopus 로고
    • MDM2 inhibits PCAF (p300/CREB-binding protein-associated factor)-mediated p53 acetylation
    • Jin, Y., Zeng, S.X., Dai, M.-S., Yang, X.-J., Lu, H., 2002. MDM2 inhibits PCAF (p300/CREB-binding protein-associated factor)-mediated p53 acetylation. J. Biol. Chem. 277, 30838-30843.
    • (2002) J. Biol. Chem. , vol.277 , pp. 30838-30843
    • Jin, Y.1    Zeng, S.X.2    Dai, M.-S.3    Yang, X.-J.4    Lu, H.5
  • 65
    • 0034570402 scopus 로고    scopus 로고
    • p53 modulation of DNA topoisomerase II alpha gene expression
    • Joshi, A.A., Wang, Q., Suttle, D.P., 2000. p53 modulation of DNA topoisomerase II alpha gene expression. Cell Biochem. Biophys. 33, 209-216.
    • (2000) Cell Biochem. Biophys. , vol.33 , pp. 209-216
    • Joshi, A.A.1    Wang, Q.2    Suttle, D.P.3
  • 67
    • 0037053298 scopus 로고    scopus 로고
    • The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c
    • Karpinich, N.O., Tafan, M., Rothman, R.J., Russo, M.A., Farber, J.L., 2002. The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c. J. Biol. Chem. 277, 16547-16552.
    • (2002) J. Biol. Chem. , vol.277 , pp. 16547-16552
    • Karpinich, N.O.1    Tafan, M.2    Rothman, R.J.3    Russo, M.A.4    Farber, J.L.5
  • 68
    • 0036581664 scopus 로고    scopus 로고
    • Degradation of ATM-independent decatenation checkpoint function in human cells is secondary to inactivation of p53 and correlated with chromosomal destabilization
    • Kaufmann, W.K., Campbell, C.B., Simpson, D.A., Deming, P.B., Filatov, L., Galloway, D.A., Zhao, X.J., Creighton, A.M., Downes, C.S., 2002. Degradation of ATM-independent decatenation checkpoint function in human cells is secondary to inactivation of p53 and correlated with chromosomal destabilization. Cell Cycle 1, 210-219.
    • (2002) Cell Cycle , vol.1 , pp. 210-219
    • Kaufmann, W.K.1    Campbell, C.B.2    Simpson, D.A.3    Deming, P.B.4    Filatov, L.5    Galloway, D.A.6    Zhao, X.J.7    Creighton, A.M.8    Downes, C.S.9
  • 70
    • 0035138823 scopus 로고    scopus 로고
    • p53 induction and apoptosis in response to radio- and chemotherapy in vivo is tumor-type-dependent
    • Kemp, C.J., Sun, S., Gurley, K.E., 2001. p53 induction and apoptosis in response to radio- and chemotherapy in vivo is tumor-type-dependent. Cancer Res. 61, 327-332.
    • (2001) Cancer Res. , vol.61 , pp. 327-332
    • Kemp, C.J.1    Sun, S.2    Gurley, K.E.3
  • 73
    • 0034904368 scopus 로고    scopus 로고
    • p53, bcl-2 and thymidine phosphorylase as predictive markers of chemotherapy in patients with advanced and recurrent gastric cancer
    • Kikuyama, S., Inada, T., Shimizu, K., Miyakita, M., Ogata, T., 2001. p53, bcl-2 and thymidine phosphorylase as predictive markers of chemotherapy in patients with advanced and recurrent gastric cancer. Anticancer Res. 21, 2149-2153.
    • (2001) Anticancer Res. , vol.21 , pp. 2149-2153
    • Kikuyama, S.1    Inada, T.2    Shimizu, K.3    Miyakita, M.4    Ogata, T.5
  • 74
    • 0035127250 scopus 로고    scopus 로고
    • Growth inhibition and chemosensitivity of poorly differentiated human thyroid cancer cell line (NPA) transfected with p53 gene
    • Kim, S.B., Ahn, I.M., Park, H.J., Park, J.S., Cho, H.J., Gong, G., Suh, C., Lee, J.S., Kim, W.K., Kim, S.H., 2001. Growth inhibition and chemosensitivity of poorly differentiated human thyroid cancer cell line (NPA) transfected with p53 gene. Head Neck 23, 223-229.
    • (2001) Head Neck , vol.23 , pp. 223-229
    • Kim, S.B.1    Ahn, I.M.2    Park, H.J.3    Park, J.S.4    Cho, H.J.5    Gong, G.6    Suh, C.7    Lee, J.S.8    Kim, W.K.9    Kim, S.H.10
  • 75
    • 0039594628 scopus 로고    scopus 로고
    • The p53 tumor suppressor stimulates the catalytic activity of human topoisomerase IIα by enhancing the rate of ATP hydrolysis
    • Kwon, Y., Shin, B.S., Chung, I.K., 2000. The p53 tumor suppressor stimulates the catalytic activity of human topoisomerase IIα by enhancing the rate of ATP hydrolysis. J. Biol. Chem. 275, 18503-18510.
    • (2000) J. Biol. Chem. , vol.275 , pp. 18503-18510
    • Kwon, Y.1    Shin, B.S.2    Chung, I.K.3
  • 76
    • 0035883083 scopus 로고    scopus 로고
    • Signaling pathways activated by daunorubicin
    • Laurent, G., Jaffrezou, J.-P., 2001. Signaling pathways activated by daunorubicin. Blood 98, 913-924.
    • (2001) Blood , vol.98 , pp. 913-924
    • Laurent, G.1    Jaffrezou, J.-P.2
  • 77
    • 0034915413 scopus 로고    scopus 로고
    • Tumor suppression and therapy sensitization of localized and metastatic breast cancer by adenovirus p53
    • Lebedeva, S., Bagdasarova, S., Tyler, T., Mu, X., Wilson, D.R., Gjerset, R.A., 2001. Tumor suppression and therapy sensitization of localized and metastatic breast cancer by adenovirus p53. Hum. Gene Ther. 12, 763-772.
    • (2001) Hum. Gene Ther. , vol.12 , pp. 763-772
    • Lebedeva, S.1    Bagdasarova, S.2    Tyler, T.3    Mu, X.4    Wilson, D.R.5    Gjerset, R.A.6
  • 78
    • 0037151072 scopus 로고    scopus 로고
    • SWI/SNF complex interacts with tumor suppressor p53 and is necessary for the activation of p53-mediated transcription
    • Lee, D., Kim, J.W., Seo, T., Hwang, S.G., Choi, E.-J., Choe, J., 2002a. SWI/SNF complex interacts with tumor suppressor p53 and is necessary for the activation of p53-mediated transcription. J. Biol. Chem. 277, 22330-22337.
    • (2002) J. Biol. Chem. , vol.277 , pp. 22330-22337
    • Lee, D.1    Kim, J.W.2    Seo, T.3    Hwang, S.G.4    Choi, E.-J.5    Choe, J.6
  • 79
    • 0036137529 scopus 로고    scopus 로고
    • Doxorubicin-induced apoptosis and chemosensitivity in hepatoma cell lines
    • Lee, T.K., Lau, T.C., Ng, I.O., 2002b. Doxorubicin-induced apoptosis and chemosensitivity in hepatoma cell lines. Cancer Chemother. Pharmacol. 49, 78-86.
    • (2002) Cancer Chemother. Pharmacol. , vol.49 , pp. 78-86
    • Lee, T.K.1    Lau, T.C.2    Ng, I.O.3
  • 80
    • 0035866361 scopus 로고    scopus 로고
    • p53 modulates the effect of loss of DNA mismatch repair on the sensitivity of human colon cancer cells to the cytotoxic and mutagenic effects of cisplatin
    • Lin, X., Ramamurthi, K., Mishima, M., Kondo, A., Christen, R.D., Howell, S.B., 2001. p53 modulates the effect of loss of DNA mismatch repair on the sensitivity of human colon cancer cells to the cytotoxic and mutagenic effects of cisplatin. Cancer Res. 61, 1508-1516.
    • (2001) Cancer Res. , vol.61 , pp. 1508-1516
    • Lin, X.1    Ramamurthi, K.2    Mishima, M.3    Kondo, A.4    Christen, R.D.5    Howell, S.B.6
  • 81
    • 0037089019 scopus 로고    scopus 로고
    • Topoisomerase IIalpha gene expression is regulated by the p53 tumor suppressor gene in non-small cell lung carcinoma patients
    • Liu, D., Huang, C.L., Kameyama, K., Hayashi, E., Yamauchi, A., Sumimoto, S., Yokomise, H., 2002a. Topoisomerase IIalpha gene expression is regulated by the p53 tumor suppressor gene in non-small cell lung carcinoma patients. Cancer 94, 2239-2247.
    • (2002) Cancer , vol.94 , pp. 2239-2247
    • Liu, D.1    Huang, C.L.2    Kameyama, K.3    Hayashi, E.4    Yamauchi, A.5    Sumimoto, S.6    Yokomise, H.7
  • 83
    • 0036738226 scopus 로고    scopus 로고
    • Exposure to low concentrations of etoposide reduces the apoptotic capability of leukaemic cell lines
    • Liu, W.M., Oakley, P.R., Joel, S.P., 2002c. Exposure to low concentrations of etoposide reduces the apoptotic capability of leukaemic cell lines. Leukemia 16, 1705-1712.
    • (2002) Leukemia , vol.16 , pp. 1705-1712
    • Liu, W.M.1    Oakley, P.R.2    Joel, S.P.3
  • 84
    • 0037115757 scopus 로고    scopus 로고
    • Characterization of the human topoisomerase II beta (TOP2B) promoter activity: Essential roles of the NF-Y and Sp1 binding sites
    • Lok, C.N., Lang, A.J., Mirski, S.E., Cole, S.P., 2002. Characterization of the human topoisomerase II beta (TOP2B) promoter activity: essential roles of the NF-Y and Sp1 binding sites. Biochem. J. 368, 741-751.
    • (2002) Biochem. J. , vol.368 , pp. 741-751
    • Lok, C.N.1    Lang, A.J.2    Mirski, S.E.3    Cole, S.P.4
  • 86
    • 0031787528 scopus 로고    scopus 로고
    • Expression of DNA topoisomerase I, DNA topoisomerase II-alpha, and p53 in metastatic malignant melanoma
    • Lynch, B.J., Komaromy-Hiller, G., Bronstein, I.B., Holden, J.A., 1998. Expression of DNA topoisomerase I, DNA topoisomerase II-alpha, and p53 in metastatic malignant melanoma. Hum. Pathol. 29, 1240-1245.
    • (1998) Hum. Pathol. , vol.29 , pp. 1240-1245
    • Lynch, B.J.1    Komaromy-Hiller, G.2    Bronstein, I.B.3    Holden, J.A.4
  • 87
    • 0035821788 scopus 로고    scopus 로고
    • p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents
    • Mahyar-Roemer, M., Roemer, K., 2001. p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents. Oncogene 20, 3387-3398.
    • (2001) Oncogene , vol.20 , pp. 3387-3398
    • Mahyar-Roemer, M.1    Roemer, K.2
  • 88
    • 0035682833 scopus 로고    scopus 로고
    • Expression of p21 and bcl-2 proteins and p53 mRNA in surgically resected preparations of non-small cell lung cancer (stage IIIA) after etoposide and cisplatin chemotherapy
    • Mandziuk, S., Dudzisz-Sledz, M., Rybacka-Chabros, B., Zdunek, M., Jakubowicz-Klecha, A., Korobowicz, E., Milanowski, J., Wojcierowski, J., 2001. Expression of p21 and bcl-2 proteins and p53 mRNA in surgically resected preparations of non-small cell lung cancer (stage IIIA) after etoposide and cisplatin chemotherapy. Folia. Histochem. Cytobiol. 39 (Suppl. 2), 175-176.
    • (2001) Folia. Histochem. Cytobiol. , vol.39 , Issue.SUPPL. 2 , pp. 175-176
    • Mandziuk, S.1    Dudzisz-Sledz, M.2    Rybacka-Chabros, B.3    Zdunek, M.4    Jakubowicz-Klecha, A.5    Korobowicz, E.6    Milanowski, J.7    Wojcierowski, J.8
  • 89
    • 0035798622 scopus 로고    scopus 로고
    • 26S proteasome-mediated degradation of topoisomerase II cleavable complexes
    • Mao, Y., Desai, S.D., Ting, C.-Y., Hwang, J., Liu, L.F., 2001. 26S proteasome-mediated degradation of topoisomerase II cleavable complexes. J. Biol. Chem. 276, 40652-40658.
    • (2001) J. Biol. Chem. , vol.276 , pp. 40652-40658
    • Mao, Y.1    Desai, S.D.2    Ting, C.-Y.3    Hwang, J.4    Liu, L.F.5
  • 90
    • 0034662642 scopus 로고    scopus 로고
    • p53 dependence of topoisomerase I recruitment in vivo
    • Mao, Y., Okada, S., Chang, L.-S., Muller, M.T., 2000. p53 dependence of topoisomerase I recruitment in vivo. Cancer Res. 60, 4538-4543.
    • (2000) Cancer Res. , vol.60 , pp. 4538-4543
    • Mao, Y.1    Okada, S.2    Chang, L.-S.3    Muller, M.T.4
  • 91
    • 0035421961 scopus 로고    scopus 로고
    • Integrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosis
    • Matas, D., Sigal, A., Stambolsky, P., Milyavsky, M., Weisz, L., Schwartz, D., Goldfinger, N., Rotter, V., 2001. Integrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosis. EMBO J. 20, 4163-4172.
    • (2001) EMBO J. , vol.20 , pp. 4163-4172
    • Matas, D.1    Sigal, A.2    Stambolsky, P.3    Milyavsky, M.4    Weisz, L.5    Schwartz, D.6    Goldfinger, N.7    Rotter, V.8
  • 92
    • 0037085271 scopus 로고    scopus 로고
    • PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy
    • Mayo, L.D., Dixon, J.E., Durden, D.L., Tonks, N.K., Donner, D.B., 2002. PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy. J. Biol. Chem. 277, 5484-5489.
    • (2002) J. Biol. Chem. , vol.277 , pp. 5484-5489
    • Mayo, L.D.1    Dixon, J.E.2    Durden, D.L.3    Tonks, N.K.4    Donner, D.B.5
  • 94
    • 0036784608 scopus 로고    scopus 로고
    • Efficient specific DNA binding by p53 requires both its central and C-terminal domains as revealed by studies with high-mobility group 1 protein
    • McKinney, K., Prives, C., 2002. Efficient specific DNA binding by p53 requires both its central and C-terminal domains as revealed by studies with high-mobility group 1 protein. Mol. Cell Biol. 22, 6798-6808.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 6798-6808
    • McKinney, K.1    Prives, C.2
  • 95
    • 0033849410 scopus 로고    scopus 로고
    • Altered expression of DNA-topoisomerase IIα is associated with increased rate of spontaneous polyploidization in etoposide resistant K562 cells
    • Melixetian, M.B., Beryozkina, E., Pavlenko, M.A., Grinchuk, T.M., 2000. Altered expression of DNA-topoisomerase IIα is associated with increased rate of spontaneous polyploidization in etoposide resistant K562 cells. Leuk. Res. 24, 831-837.
    • (2000) Leuk. Res. , vol.24 , pp. 831-837
    • Melixetian, M.B.1    Beryozkina, E.2    Pavlenko, M.A.3    Grinchuk, T.M.4
  • 96
    • 0031574263 scopus 로고    scopus 로고
    • Bipartite nuclear localization signals in the C-terminus of human topoisomerase II alpha
    • Mirski, S.E., Gerlach, J.H., Cummings, H.J., Zirngibl, R., Greer, P.A., Cole, S.P., 1997. Bipartite nuclear localization signals in the C-terminus of human topoisomerase II alpha. Exp. Cell Res. 237, 452-455.
    • (1997) Exp. Cell Res. , vol.237 , pp. 452-455
    • Mirski, S.E.1    Gerlach, J.H.2    Cummings, H.J.3    Zirngibl, R.4    Greer, P.A.5    Cole, S.P.6
  • 98
    • 0037179872 scopus 로고    scopus 로고
    • High incidence of protein-truncating mutations of the p53 gene in liver metastases of colorectal carcinomas
    • Miyaki, M., Iijima, T., Yasuno, M., Kita, Y., Hishima, T., Kuroki, T., Mori, T., 2002. High incidence of protein-truncating mutations of the p53 gene in liver metastases of colorectal carcinomas. Oncogene 21, 6689-6693.
    • (2002) Oncogene , vol.21 , pp. 6689-6693
    • Miyaki, M.1    Iijima, T.2    Yasuno, M.3    Kita, Y.4    Hishima, T.5    Kuroki, T.6    Mori, T.7
  • 99
    • 0032893502 scopus 로고    scopus 로고
    • Elevations of DNA topoisomerase I in transitional cell carcinoma of the urinary bladder: Correlation with DNA topoisomerase II-alpha and p53 expression
    • Monnin, K.A., Bronstein, I.B., Gaffney, D.K., Holden, J.A., 1999. Elevations of DNA topoisomerase I in transitional cell carcinoma of the urinary bladder: correlation with DNA topoisomerase II-alpha and p53 expression. Hum. Pathol. 30, 384-391.
    • (1999) Hum. Pathol. , vol.30 , pp. 384-391
    • Monnin, K.A.1    Bronstein, I.B.2    Gaffney, D.K.3    Holden, J.A.4
  • 100
    • 0036127530 scopus 로고    scopus 로고
    • A role for p53 in the frequency and mechanism of mutation
    • Morris, S.M., 2002. A role for p53 in the frequency and mechanism of mutation. Mutat. Res. 511, 45-62.
    • (2002) Mutat. Res. , vol.511 , pp. 45-62
    • Morris, S.M.1
  • 103
    • 0037150226 scopus 로고    scopus 로고
    • C-terminus of p53 is required for G(2) arrest
    • Nakamura, S., Gomyo, Y., Roth, J.A., Mukhopadhyay, T., 2002. C-terminus of p53 is required for G(2) arrest. Oncogene 21, 2102-2107.
    • (2002) Oncogene , vol.21 , pp. 2102-2107
    • Nakamura, S.1    Gomyo, Y.2    Roth, J.A.3    Mukhopadhyay, T.4
  • 105
    • 0037126383 scopus 로고    scopus 로고
    • Stabilization of p53 and transactivation of its target genes in response to replication blockade
    • Nayak, B.K., Das, G.M., 2002. Stabilization of p53 and transactivation of its target genes in response to replication blockade. Oncogene 21, 7226-7229.
    • (2002) Oncogene , vol.21 , pp. 7226-7229
    • Nayak, B.K.1    Das, G.M.2
  • 106
    • 0036462585 scopus 로고    scopus 로고
    • Emerging new therapies for chemotherapy-resistant cancer using adenoviral vectors
    • Nemunaitis, J., Cunningham, C., 2002. Emerging new therapies for chemotherapy-resistant cancer using adenoviral vectors. Drug Resist. Updates 5, 34-46.
    • (2002) Drug Resist. Updates , vol.5 , pp. 34-46
    • Nemunaitis, J.1    Cunningham, C.2
  • 108
    • 0034570214 scopus 로고    scopus 로고
    • Topoisomerase II alpha mediates E2F-1-induced chemosensitivity and is a target for p53-mediated transcriptional repression
    • Nip, J., Hiebert, S.W., 2000. Topoisomerase II alpha mediates E2F-1-induced chemosensitivity and is a target for p53-mediated transcriptional repression. Cell Biochem. Biophys. 33, 199-207.
    • (2000) Cell Biochem. Biophys. , vol.33 , pp. 199-207
    • Nip, J.1    Hiebert, S.W.2
  • 109
    • 0030865104 scopus 로고    scopus 로고
    • Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents
    • O'Connor, P.M., Jackman, J., Bae, I., Myers, T.G., Fan, S., Mutoh, M., Scudiero, D.A., Monks, A., Sausville, E.A., Weinstein, J.N., Friend, S., Fornace, Jr., A.J., Kohn, K.W., 1997. Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents. Cancer Res. 57, 4285-4300.
    • (1997) Cancer Res. , vol.57 , pp. 4285-4300
    • O'Connor, P.M.1    Jackman, J.2    Bae, I.3    Myers, T.G.4    Fan, S.5    Mutoh, M.6    Scudiero, D.A.7    Monks, A.8    Sausville, E.A.9    Weinstein, J.N.10    Friend, S.11    Fornace A.J., Jr.12    Kohn, K.W.13
  • 110
    • 0036735384 scopus 로고    scopus 로고
    • Nuclear localization of proteasomes participates in stress-inducible resistance of solid tumors cells to topoisomerase II-directed drugs
    • Ogiso, Y., Tomida, A., Tsuruo, T., 2002. Nuclear localization of proteasomes participates in stress-inducible resistance of solid tumors cells to topoisomerase II-directed drugs. Cancer Res. 62, 5008-5012.
    • (2002) Cancer Res. , vol.62 , pp. 5008-5012
    • Ogiso, Y.1    Tomida, A.2    Tsuruo, T.3
  • 111
    • 0031309082 scopus 로고    scopus 로고
    • Proteolytic cleavage of p53: A model for the activation of p53 in response to DNA damage
    • Okorokov, A.L., Milner, J., 1997. Proteolytic cleavage of p53: a model for the activation of p53 in response to DNA damage. Oncology Res. 9, 267-273.
    • (1997) Oncology Res. , vol.9 , pp. 267-273
    • Okorokov, A.L.1    Milner, J.2
  • 112
    • 0030826733 scopus 로고    scopus 로고
    • Induced N- and C-terminal cleavage of p53: A core fragment of p53, generated by interaction with damaged DNA, promotes cleavage of the N-terminus of full-length p53, whereas ssDNA induces C-terminal cleavage of p53
    • Okorokov, A.L., Ponchel, F., Milner, J., 1997. Induced N- and C-terminal cleavage of p53: a core fragment of p53, generated by interaction with damaged DNA, promotes cleavage of the N-terminus of full-length p53, whereas ssDNA induces C-terminal cleavage of p53. EMBO J. 16, 6008-6017.
    • (1997) EMBO J. , vol.16 , pp. 6008-6017
    • Okorokov, A.L.1    Ponchel, F.2    Milner, J.3
  • 113
    • 0036728997 scopus 로고    scopus 로고
    • p53 null mutations detected by a p53 yeast functional assay predict a poor outcome in young esophageal carcinoma patients
    • Osugi, H., Morimura, K., Okuda, E., Takemura, M., Higashino, M., Takada, N., Kinoshita, H., 2002. p53 null mutations detected by a p53 yeast functional assay predict a poor outcome in young esophageal carcinoma patients. Int. J. Oncol. 21, 637-641.
    • (2002) Int. J. Oncol. , vol.21 , pp. 637-641
    • Osugi, H.1    Morimura, K.2    Okuda, E.3    Takemura, M.4    Higashino, M.5    Takada, N.6    Kinoshita, H.7
  • 114
    • 0034806033 scopus 로고    scopus 로고
    • Vitamin C augments chemotherapeutic response of cervical carcinoma HeLa cells by stabilizing p53
    • Reddy, G., Khanna, N., Singh, N., 2001. Vitamin C augments chemotherapeutic response of cervical carcinoma HeLa cells by stabilizing p53. Biochem. Biophys. Res. Commun. 282, 409-415.
    • (2001) Biochem. Biophys. Res. Commun. , vol.282 , pp. 409-415
    • Reddy, G.1    Khanna, N.2    Singh, N.3
  • 116
    • 0035162434 scopus 로고    scopus 로고
    • MDM2 mediated nuclear exclusion of p53 attenuates etoposide-induced apoptosis in neuroblastoma cells
    • Rodriguez-Lopez, A., Xenaki, D., Eden, T.O.B., Hickman, J.A., Chresta, C.M., 2000. MDM2 mediated nuclear exclusion of p53 attenuates etoposide-induced apoptosis in neuroblastoma cells. Mol. Pharmacol. 59, 135-143.
    • (2000) Mol. Pharmacol. , vol.59 , pp. 135-143
    • Rodriguez-Lopez, A.1    Xenaki, D.2    Eden, T.O.B.3    Hickman, J.A.4    Chresta, C.M.5
  • 117
    • 0036815596 scopus 로고    scopus 로고
    • Tumor senescence as a determinant of drug response in vivo
    • Roninson, I.B., 2002. Tumor senescence as a determinant of drug response in vivo. Drug Resist. Updates 5, 204-208.
    • (2002) Drug Resist. Updates , vol.5 , pp. 204-208
    • Roninson, I.B.1
  • 118
    • 0035736138 scopus 로고    scopus 로고
    • If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells
    • Roninson, I.B., Broude, E.V., Chang, B.-D., 2001. If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells. Drug Resist. Updates 4, 303-313.
    • (2001) Drug Resist. Updates , vol.4 , pp. 303-313
    • Roninson, I.B.1    Broude, E.V.2    Chang, B.-D.3
  • 120
    • 0036059108 scopus 로고    scopus 로고
    • MDMX inhibits the p300/CBP-mediated acetylation of p53
    • Sabbatini, P., McCormick, F., 2002. MDMX inhibits the p300/CBP-mediated acetylation of p53. DNA Cell Biol. 21, 519-525.
    • (2002) DNA Cell Biol. , vol.21 , pp. 519-525
    • Sabbatini, P.1    McCormick, F.2
  • 121
    • 0035873741 scopus 로고    scopus 로고
    • A novel role for the bcl-2 protein family: Specific suppression of the RAD51 recombination pathway
    • Saintigny, Y., Dumay, S., Lambert, S., Lopez, B.S., 2001. A novel role for the bcl-2 protein family: specific suppression of the RAD51 recombination pathway. EMBO J. 20, 2596-2607.
    • (2001) EMBO J. , vol.20 , pp. 2596-2607
    • Saintigny, Y.1    Dumay, S.2    Lambert, S.3    Lopez, B.S.4
  • 122
    • 0036739602 scopus 로고    scopus 로고
    • Epitope distribution of randomly established monoclonal antibodies against human type II DNA topoisomerases
    • Sakaguchi, A., Miyaike, M., Kuroda, K., Nozaki, N., Tanaka, M., Hibino, M., Fujii, Y., Kato, S., Kikuchi, A., 2002. Epitope distribution of randomly established monoclonal antibodies against human type II DNA topoisomerases. J. Biochem. 132, 409-416.
    • (2002) J. Biochem. , vol.132 , pp. 409-416
    • Sakaguchi, A.1    Miyaike, M.2    Kuroda, K.3    Nozaki, N.4    Tanaka, M.5    Hibino, M.6    Fujii, Y.7    Kato, S.8    Kikuchi, A.9
  • 123
    • 0035313393 scopus 로고    scopus 로고
    • Role of proteasomal degradation in the cell cycle-dependent regulation of DNA topoisomerase IIα expression
    • Salmena, L., Lam, V., McPherson, J.P., Goldenberg, G.J., 2001. Role of proteasomal degradation in the cell cycle-dependent regulation of DNA topoisomerase IIα expression. Biochem. Pharmacol. 61, 795-802.
    • (2001) Biochem. Pharmacol. , vol.61 , pp. 795-802
    • Salmena, L.1    Lam, V.2    McPherson, J.P.3    Goldenberg, G.J.4
  • 124
    • 0034834092 scopus 로고    scopus 로고
    • Adenovirus-mediated transfer of the p53 family genes, p73 and p51/p63 induces cell cycle arrest and apoptosis in colorectal cancer cell lines: Potential application to gene therapy of colorectal cancer
    • Sasaki, Y., Morimoto, I., Ishida, S., Yamashita, T., Imai, K., Tokino, T., 2001. Adenovirus-mediated transfer of the p53 family genes, p73 and p51/p63 induces cell cycle arrest and apoptosis in colorectal cancer cell lines: potential application to gene therapy of colorectal cancer. Gene Ther. 8, 1401-1408.
    • (2001) Gene Ther. , vol.8 , pp. 1401-1408
    • Sasaki, Y.1    Morimoto, I.2    Ishida, S.3    Yamashita, T.4    Imai, K.5    Tokino, T.6
  • 126
    • 0034930374 scopus 로고    scopus 로고
    • Apoptosis is critical for drug response in vivo
    • Schmitt, C.A., Lowe, S.W., 2001. Apoptosis is critical for drug response in vivo. Drug Resist. Updates 4, 132-134.
    • (2001) Drug Resist. Updates , vol.4 , pp. 132-134
    • Schmitt, C.A.1    Lowe, S.W.2
  • 128
    • 85031210071 scopus 로고    scopus 로고
    • The effect of functional and mutant p53 on M-VAC therapy in human bladder cancer: Implications for molecular targeting of neoadjuvant chemotherapy
    • Abstr.# 1257
    • Shah, N.L., Kielb, S.J., Sanda, M.G., 2002. The effect of functional and mutant p53 on M-VAC therapy in human bladder cancer: implications for molecular targeting of neoadjuvant chemotherapy. Proc. AACR Abstr.# 1257.
    • (2002) Proc. AACR
    • Shah, N.L.1    Kielb, S.J.2    Sanda, M.G.3
  • 129
    • 0036289330 scopus 로고    scopus 로고
    • p53 inhibits adriamycin-induced down-regulation of cyclin D1 expression in human cancer cells
    • Shao, J., Teraishi, F., Katsuda, K., Tanaka, N., Fujiwara, T., 2002. p53 inhibits adriamycin-induced down-regulation of cyclin D1 expression in human cancer cells. Biochem. Biophys. Res. Commun. 290, 1101-1107.
    • (2002) Biochem. Biophys. Res. Commun. , vol.290 , pp. 1101-1107
    • Shao, J.1    Teraishi, F.2    Katsuda, K.3    Tanaka, N.4    Fujiwara, T.5
  • 132
    • 0035888245 scopus 로고    scopus 로고
    • Drug-resistant human bladder-cancer cells are more sensitive to adenovirus-mediated wild-type p53 gene therapy compared to drug-sensitive cells
    • Shirakawa, T., Sasaki, R., Gardiner, T.A., Kao, C., Zhang, Z.-J., Sugumura, K., Matsua, M., Kamidono, S., Gotoh, A., 2001. Drug-resistant human bladder-cancer cells are more sensitive to adenovirus-mediated wild-type p53 gene therapy compared to drug-sensitive cells. Int. J. Cancer 94, 282-289.
    • (2001) Int. J. Cancer , vol.94 , pp. 282-289
    • Shirakawa, T.1    Sasaki, R.2    Gardiner, T.A.3    Kao, C.4    Zhang, Z.-J.5    Sugumura, K.6    Matsua, M.7    Kamidono, S.8    Gotoh, A.9
  • 134
    • 0036830417 scopus 로고    scopus 로고
    • Bcl-2/bcl-xL bispecific antisense treatment sensitizes breast carcinoma cells to doxorubicin, paclitaxel and cyclophosphamide
    • Simoes-Wust, A.P., Schurpf, T., Hall, J., Stahel, R.A., Zangemeister-Wittke, U., 2002. Bcl-2/bcl-xL bispecific antisense treatment sensitizes breast carcinoma cells to doxorubicin, paclitaxel and cyclophosphamide. Breast Cancer Res. Treat. 76, 157-166.
    • (2002) Breast Cancer Res. Treat. , vol.76 , pp. 157-166
    • Simoes-Wust, A.P.1    Schurpf, T.2    Hall, J.3    Stahel, R.A.4    Zangemeister-Wittke, U.5
  • 135
    • 0034612585 scopus 로고    scopus 로고
    • Substrate specificity of the p53-associated 3′-5′ exonuclease
    • Skalsky, V., Lin, Z.-Y., Choi, B.Y., Brown, K.R., 2000. Substrate specificity of the p53-associated 3′-5′ exonuclease. Oncogene 19, 3321-3329.
    • (2000) Oncogene , vol.19 , pp. 3321-3329
    • Skalsky, V.1    Lin, Z.-Y.2    Choi, B.Y.3    Brown, K.R.4
  • 136
    • 0035977949 scopus 로고    scopus 로고
    • Combination treatment for osteosarcoma with baculoviral vector mediated gene therapy (p53) and chemotherapy (adriamycin)
    • Song, S.U., Boyce, F.M., 2001. Combination treatment for osteosarcoma with baculoviral vector mediated gene therapy (p53) and chemotherapy (adriamycin). Exp. Mol. Med. 33, 46-53.
    • (2001) Exp. Mol. Med. , vol.33 , pp. 46-53
    • Song, S.U.1    Boyce, F.M.2
  • 137
    • 0034919970 scopus 로고    scopus 로고
    • Differential sensitivity to etoposide (VP-16)-induced S phase delay in a panel of small-cell lung carcinoma cell lines with G1/S phase checkpoint dysfunction
    • Soues, S., Wiltshire, M., Smith, P.J., 2001. Differential sensitivity to etoposide (VP-16)-induced S phase delay in a panel of small-cell lung carcinoma cell lines with G1/S phase checkpoint dysfunction. Cancer Chemother. Pharmacol. 47, 133-140.
    • (2001) Cancer Chemother. Pharmacol. , vol.47 , pp. 133-140
    • Soues, S.1    Wiltshire, M.2    Smith, P.J.3
  • 138
    • 0033559256 scopus 로고    scopus 로고
    • A leucine-rich nuclear export signal in the p53 tetramerization domain: Regulation of subcellular localization and p53 activity by NES masking
    • Stommel, J.M., Marchenko, N.D., Jimenez, G.S., Moll, U.M., Hope, T.J., Wahl, G.M., 1999. A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking. EMBO J. 18, 1660-1672.
    • (1999) EMBO J. , vol.18 , pp. 1660-1672
    • Stommel, J.M.1    Marchenko, N.D.2    Jimenez, G.S.3    Moll, U.M.4    Hope, T.J.5    Wahl, G.M.6
  • 139
    • 85047687410 scopus 로고    scopus 로고
    • The mutant p53-conformation modifying drug, CP-31398, can induce apoptosis of human cancer cells and can stabilize wild-type p53 protein
    • Takimoto, R., Wang, W., Dicker, D.T., Rastinejad, F., Lyssikatos, J., el-Deiry, W.S., 2002. The mutant p53-conformation modifying drug, CP-31398, can induce apoptosis of human cancer cells and can stabilize wild-type p53 protein. Cancer Biol. Ther. 1, 47-55.
    • (2002) Cancer Biol. Ther. , vol.1 , pp. 47-55
    • Takimoto, R.1    Wang, W.2    Dicker, D.T.3    Rastinejad, F.4    Lyssikatos, J.5    El-Deiry, W.S.6
  • 140
    • 0037048323 scopus 로고    scopus 로고
    • Loss of p53 and centrosome hyperamplification
    • Tarapore, P., Fukasawa, K., 2002. Loss of p53 and centrosome hyperamplification. Oncogene 21, 6234-6240.
    • (2002) Oncogene , vol.21 , pp. 6234-6240
    • Tarapore, P.1    Fukasawa, K.2
  • 143
    • 0036304758 scopus 로고    scopus 로고
    • Catalytic inhibitors of topoisomerase II are DNA-damaging agents: Induction of chromosomal damage by merbarone and ICRF-187
    • Wang, L., Eastmond, D.A., 2002. Catalytic inhibitors of topoisomerase II are DNA-damaging agents: induction of chromosomal damage by merbarone and ICRF-187. Environ. Mol. Mutagen. 39, 348-356.
    • (2002) Environ. Mol. Mutagen. , vol.39 , pp. 348-356
    • Wang, L.1    Eastmond, D.A.2
  • 144
    • 0031014797 scopus 로고    scopus 로고
    • Inhibition of DNA topoisomerase IIα gene expression by the p53 tumor suppressor
    • Wang, Q., Zambetti, G.P., Suttle, D.P., 1997. Inhibition of DNA topoisomerase IIα gene expression by the p53 tumor suppressor. Mol. Cell. Biol. 17, 389-397.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 389-397
    • Wang, Q.1    Zambetti, G.P.2    Suttle, D.P.3
  • 145
    • 0036327669 scopus 로고    scopus 로고
    • Prognostic significance of DNA topoisomerase IIalpha expression in human hepatocellular carcinoma
    • Watanuki, A., Ohwada, S., Fukusato, T., Makita, F., Yamada, T., Kikuchi, A., Morishita, Y., 2002. Prognostic significance of DNA topoisomerase IIalpha expression in human hepatocellular carcinoma. Anticancer Res. 22, 1113-1119.
    • (2002) Anticancer Res. , vol.22 , pp. 1113-1119
    • Watanuki, A.1    Ohwada, S.2    Fukusato, T.3    Makita, F.4    Yamada, T.5    Kikuchi, A.6    Morishita, Y.7
  • 146
    • 0037012034 scopus 로고    scopus 로고
    • Caspase 9 is required for p53-dependent apoptosis and chemosensitivity in a human ovarian cancer cell line
    • Wu, G.S., Ding, Z., 2002. Caspase 9 is required for p53-dependent apoptosis and chemosensitivity in a human ovarian cancer cell line. Oncogene 21, 1-8.
    • (2002) Oncogene , vol.21 , pp. 1-8
    • Wu, G.S.1    Ding, Z.2
  • 147
    • 85031199418 scopus 로고    scopus 로고
    • Topoisomerase II-dependent cell cycle G2/M arrest is distinct from DNA damage arrest
    • Abstr.# 3104
    • Wu, Z., Suttle, D.P., 2002. Topoisomerase II-dependent cell cycle G2/M arrest is distinct from DNA damage arrest. Proc. AACR Abstr.# 3104.
    • (2002) Proc. AACR
    • Wu, Z.1    Suttle, D.P.2
  • 148
    • 0342902189 scopus 로고    scopus 로고
    • Additive effect of adenovirus-mediated E2F-1 gene transfer and topoisomerase II inhibitors on apoptosis in human osteosarcoma cells
    • Yang, H.L., Dong, Y.B., Elliott, M.J., Wong, S.L., McMasters, K.M., 2001. Additive effect of adenovirus-mediated E2F-1 gene transfer and topoisomerase II inhibitors on apoptosis in human osteosarcoma cells. Cancer Gene Ther. 8, 241-251.
    • (2001) Cancer Gene Ther. , vol.8 , pp. 241-251
    • Yang, H.L.1    Dong, Y.B.2    Elliott, M.J.3    Wong, S.L.4    McMasters, K.M.5
  • 149
    • 0033862298 scopus 로고    scopus 로고
    • Wild-type p53-dependent etoposide-induced apoptosis mediated by caspase-3 activation in human glioma cells
    • Yin, D., Tamaki, N., Kokunai, T., 2000. Wild-type p53-dependent etoposide-induced apoptosis mediated by caspase-3 activation in human glioma cells. J. Neurosurg. 93, 289-297.
    • (2000) J. Neurosurg. , vol.93 , pp. 289-297
    • Yin, D.1    Tamaki, N.2    Kokunai, T.3
  • 150
    • 0025647116 scopus 로고
    • Eukaryotic topoisomerases recognize nuclei acid topology by preferentially interacting with DNA crossovers
    • Zechiedrich, E.L., Osheroff, N., 1990. Eukaryotic topoisomerases recognize nuclei acid topology by preferentially interacting with DNA crossovers. EMBO J. 9, 4555-4562.
    • (1990) EMBO J. , vol.9 , pp. 4555-4562
    • Zechiedrich, E.L.1    Osheroff, N.2
  • 151
    • 0035883628 scopus 로고    scopus 로고
    • Wild type p53 sensitizes soft tissue sarcoma cells to doxorubicin by down-regulating multidrug resistance-1 expression
    • Zhan, M., Yu, D., Lang, A., Li, L., Pollock, R.E., 2001. Wild type p53 sensitizes soft tissue sarcoma cells to doxorubicin by down-regulating multidrug resistance-1 expression. Cancer 92, 1556-1566.
    • (2001) Cancer , vol.92 , pp. 1556-1566
    • Zhan, M.1    Yu, D.2    Lang, A.3    Li, L.4    Pollock, R.E.5
  • 152
    • 0036785525 scopus 로고    scopus 로고
    • DNA damage induces a novel p53-survivin signaling pathway regulating cell cycle and apoptosis in acute lymphoblastic leukemia cells
    • Zhou, M., Gu, L., Li, F., Zhu, Y., Woods, W.G., Findley, H.W., 2002. DNA damage induces a novel p53-survivin signaling pathway regulating cell cycle and apoptosis in acute lymphoblastic leukemia cells. J. Pharmacol. Exp. Therap. 303, 124-131.
    • (2002) J. Pharmacol. Exp. Therap. , vol.303 , pp. 124-131
    • Zhou, M.1    Gu, L.2    Li, F.3    Zhu, Y.4    Woods, W.G.5    Findley, H.W.6
  • 153
    • 0037188898 scopus 로고    scopus 로고
    • Unrepaired DNA breaks in p53-deficient cells lead to oncogenic, gene amplification subsequent to translocations
    • Zhu, C., Mills, K.D., Ferguson, D.O., Lee, C., Manis, J., Fleming, J., Gao, Y., Morton, C.C., Alt, F.W., 2002a. Unrepaired DNA breaks in p53-deficient cells lead to oncogenic, gene amplification subsequent to translocations. Cell 109, 811-821.
    • (2002) Cell , vol.109 , pp. 811-821
    • Zhu, C.1    Mills, K.D.2    Ferguson, D.O.3    Lee, C.4    Manis, J.5    Fleming, J.6    Gao, Y.7    Morton, C.C.8    Alt, F.W.9
  • 154
    • 0036047982 scopus 로고    scopus 로고
    • Identification of promoter elements responsible for transcriptional inhibition of Polo-like Kinase 1 and topoisomerase IIalpha genes by p21 (WAF1/CIP1/SDI1)
    • Zhu, H., Chang, B.D., Uchiumi, T., Roninson, I.B., 2002b. Identification of promoter elements responsible for transcriptional inhibition of Polo-like Kinase 1 and topoisomerase IIalpha genes by p21 (WAF1/CIP1/SDI1). Cell Cycle 1, 59-66.
    • (2002) Cell Cycle , vol.1 , pp. 59-66
    • Zhu, H.1    Chang, B.D.2    Uchiumi, T.3    Roninson, I.B.4


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