-
1
-
-
0001885549
-
Antracyclines
-
Chabner BA, Collins JM, eds. Philadelphia, PA: JB Lippincott
-
Myers CE, Chabner BA. Antracyclines. In: Chabner BA, Collins JM, eds. Cancer Chemotherapy. Principles and Practice. Philadelphia, PA: JB Lippincott; 1990:356-381.
-
(1990)
Cancer Chemotherapy. Principles and Practice
, pp. 356-381
-
-
Myers, C.E.1
Chabner, B.A.2
-
2
-
-
0025872718
-
Cell surface actions of adriamycin
-
Tritton TR. Cell surface actions of adriamycin. Pharmac Ther. 1991;49:293-309.
-
(1991)
Pharmac Ther
, vol.49
, pp. 293-309
-
-
Tritton, T.R.1
-
3
-
-
0020619895
-
Relationship of adriamycin concentrations to the DNA lesions induced in hypoxic and euoxic L1210 cells
-
Potmesil M, Kirschenbaum J, Israel M, Levin M, Khetarpal VK, Silber R. Relationship of adriamycin concentrations to the DNA lesions induced in hypoxic and euoxic L1210 cells. Cancer Res. 1983;43:3528-3533.
-
(1983)
Cancer Res
, vol.43
, pp. 3528-3533
-
-
Potmesil, M.1
Kirschenbaum, J.2
Israel, M.3
Levin, M.4
Khetarpal, V.K.5
Silber, R.6
-
4
-
-
0018803120
-
Qualitative and quantitative aspects of intercalator-induced DNA strand breaks
-
Ross WE, Glaubiger K, Kohn KW. Qualitative and quantitative aspects of intercalator-induced DNA strand breaks. Biochim Biophys Acta. 1979;5629:41-50.
-
(1979)
Biochim Biophys Acta
, vol.5629
, pp. 41-50
-
-
Ross, W.E.1
Glaubiger, K.2
Kohn, K.W.3
-
5
-
-
0019958596
-
Cytotoxicity and DNA strand breaks by 5-iminodaunorubicin in mouse leukemia L1210 cells: Comparison with adriamycin and 4′-(9-acridinylamino)-methanesulfon-m-aniside
-
Zwelling LA, Kerrigan D, Michaels S. Cytotoxicity and DNA strand breaks by 5-iminodaunorubicin in mouse leukemia L1210 cells: comparison with adriamycin and 4′-(9-acridinylamino)-methanesulfon-m-aniside. Cancer Res. 1982;42:2687-2691.
-
(1982)
Cancer Res
, vol.42
, pp. 2687-2691
-
-
Zwelling, L.A.1
Kerrigan, D.2
Michaels, S.3
-
6
-
-
0029942653
-
Daunorubicin-induced internucleosomal DNA fragmentation in acute myeloid cell lines
-
Quillet-Mary A, Mansat V, Duchayne E, et al. Daunorubicin-induced internucleosomal DNA fragmentation in acute myeloid cell lines. Leukemia. 1996;10:417-425.
-
(1996)
Leukemia
, vol.10
, pp. 417-425
-
-
Quillet-Mary, A.1
Mansat, V.2
Duchayne, E.3
-
7
-
-
0029008635
-
Lack of correlation between expression and function of P-glycoprotein in acute myeloid leukemic cells
-
Bailly JD, Muller C, Jaffrézou JP, et al. Lack of correlation between expression and function of P-glycoprotein in acute myeloid leukemic cells. Leukemia. 1995;9:799-807.
-
(1995)
Leukemia
, vol.9
, pp. 799-807
-
-
Bailly, J.D.1
Muller, C.2
Jaffrézou, J.P.3
-
9
-
-
0028287960
-
Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis
-
Haimovitz-Friedmann A, Kan CC, Ehleiter D, et al. Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis. J Exp Med. 1994;180:525-535.
-
(1994)
J Exp Med
, vol.180
, pp. 525-535
-
-
Haimovitz-Friedmann, A.1
Kan, C.C.2
Ehleiter, D.3
-
10
-
-
0030006040
-
Daunorubicin induced apoptosis: Triggering of ceramide generation through sphingomyelin hydrolysis
-
Jaffrézou JP, Levade T, Bettaieb A, et al. Daunorubicin induced apoptosis: triggering of ceramide generation through sphingomyelin hydrolysis. EMBO J. 1996;15:2417-2424.
-
(1996)
EMBO J
, vol.15
, pp. 2417-2424
-
-
Jaffrézou, J.P.1
Levade, T.2
Bettaieb, A.3
-
11
-
-
0035259441
-
Lysosomal sphingomyelinase is not solicited for apoptosis signaling
-
Bezombes C, Ségui B, Cuvillier O, et al. Lysosomal sphingomyelinase is not solicited for apoptosis signaling. FASEB J. 2001;15:297-299.
-
(2001)
FASEB J
, vol.15
, pp. 297-299
-
-
Bezombes, C.1
Ségui, B.2
Cuvillier, O.3
-
12
-
-
0029148660
-
Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals
-
Bose R, Verheij M, Haimovitz-Friedman A, Scotto K, Fuks Z, Kolesnick R. Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals. Cell. 1995;82:405-414.
-
(1995)
Cell
, vol.82
, pp. 405-414
-
-
Bose, R.1
Verheij, M.2
Haimovitz-Friedman, A.3
Scotto, K.4
Fuks, Z.5
Kolesnick, R.6
-
13
-
-
0032568836
-
Involvement of de novo ceramide biosynthesis in tumor necrosis factor-α/cycloheximide-induced cerebral endothelial cell death
-
Xu J, Chen-Hsiung Y, Chen S, et al. Involvement of de novo ceramide biosynthesis in tumor necrosis factor-α/cycloheximide-induced cerebral endothelial cell death. J Biol Chem. 1998;273:16521-16526.
-
(1998)
J Biol Chem
, vol.273
, pp. 16521-16526
-
-
Xu, J.1
Chen-Hsiung, Y.2
Chen, S.3
-
14
-
-
0032553310
-
Tumor necrosis factor induces ceramide oscillations and negatively controls sphingolipid synthases by caspases in apoptotic Kym-1 cells
-
Bourteefe S, Hauber A, Döppler H, et al. Tumor necrosis factor induces ceramide oscillations and negatively controls sphingolipid synthases by caspases in apoptotic Kym-1 cells. J Biol Chem. 1998;273:31245-31251.
-
(1998)
J Biol Chem
, vol.273
, pp. 31245-31251
-
-
Bourteefe, S.1
Hauber, A.2
Döppler, H.3
-
15
-
-
0039499591
-
Positive feedback control sphingomyelinase activity by ceramide
-
Jaffrézou JP, Maestre N, Mansat V, Bezombes C, Levade T, Laurent G. Positive feedback control sphingomyelinase activity by ceramide. FASEB J. 1998;12:999-1006.
-
(1998)
FASEB J
, vol.12
, pp. 999-1006
-
-
Jaffrézou, J.P.1
Maestre, N.2
Mansat, V.3
Bezombes, C.4
Levade, T.5
Laurent, G.6
-
16
-
-
0347537940
-
Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis
-
Verheij M, Bose R, Lin XH, et al. Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. Nature. 1996;380:75-79.
-
(1996)
Nature
, vol.380
, pp. 75-79
-
-
Verheij, M.1
Bose, R.2
Lin, X.H.3
-
17
-
-
0028846952
-
Requirement of AP-1 for ceramide-induced apoptosis in human leukemia HL-60 cells
-
Sawa H, Okazaki T, Yamamoto H, et al. Requirement of AP-1 for ceramide-induced apoptosis in human leukemia HL-60 cells. J Biol Chem. 1995;270:27326-27331.
-
(1995)
J Biol Chem
, vol.270
, pp. 27326-27331
-
-
Sawa, H.1
Okazaki, T.2
Yamamoto, H.3
-
18
-
-
0028074621
-
Ras-dependent growth factor regulation of MEK kinase in PC12 cells
-
Lange-Carter CA, Johnson GL. Ras-dependent growth factor regulation of MEK kinase in PC12 cells. Science. 1994;265:1458-1461.
-
(1994)
Science
, vol.265
, pp. 1458-1461
-
-
Lange-Carter, C.A.1
Johnson, G.L.2
-
19
-
-
0000154443
-
Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death
-
Johnson NL, Gardner AM, Diener KM, et al. Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death. J Biol Chem. 1996;271:3229-3237.
-
(1996)
J Biol Chem
, vol.271
, pp. 3229-3237
-
-
Johnson, N.L.1
Gardner, A.M.2
Diener, K.M.3
-
20
-
-
14444281569
-
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signalling pathways
-
Ichijo H, Nishida E, Irie K, et al. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signalling pathways. Science. 1997;275:90-94.
-
(1997)
Science
, vol.275
, pp. 90-94
-
-
Ichijo, H.1
Nishida, E.2
Irie, K.3
-
21
-
-
0029851730
-
Role of the stress-activated/c-Jun NH2-terminal protein kinase pathway in the cellular response to adriamycin and other chemotherapeutic drugs
-
Osborn MT, Chambers TC. Role of the stress-activated/c-Jun NH2-terminal protein kinase pathway in the cellular response to adriamycin and other chemotherapeutic drugs. J Biol Chem. 1996;271:30950-30955.
-
(1996)
J Biol Chem
, vol.271
, pp. 30950-30955
-
-
Osborn, M.T.1
Chambers, T.C.2
-
22
-
-
0030272630
-
Adriamycin activates c-jun N-terminal kinase in human leukemia cells: A relevance to apoptosis
-
Yu R, Shtil AA, Tan TH, Roninson IB, Kong AN. Adriamycin activates c-jun N-terminal kinase in human leukemia cells: a relevance to apoptosis. Cancer Lett. 1996;107:73-81.
-
(1996)
Cancer Lett
, vol.107
, pp. 73-81
-
-
Yu, R.1
Shtil, A.A.2
Tan, T.H.3
Roninson, I.B.4
Kong, A.N.5
-
23
-
-
0032704158
-
Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin
-
Mansat-De Mas V, Bezombes C, Quillet-Mary A, et al. Implication of radical oxygen species in ceramide generation, c-Jun N-terminal kinase activation and apoptosis induced by daunorubicin. Mol Pharmacol. 1999;56:867-874.
-
(1999)
Mol Pharmacol
, vol.56
, pp. 867-874
-
-
Mansat-De Mas, V.1
Bezombes, C.2
Quillet-Mary, A.3
-
24
-
-
0027049804
-
The mammalian ultraviolet response is triggered by activation of Src tyrosine kinases
-
Devary Y, Gottlieb RA, Smeal T, Karin M. The mammalian ultraviolet response is triggered by activation of Src tyrosine kinases. Cell. 1992;71:1081-1091.
-
(1992)
Cell
, vol.71
, pp. 1081-1091
-
-
Devary, Y.1
Gottlieb, R.A.2
Smeal, T.3
Karin, M.4
-
25
-
-
0029098225
-
Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents
-
Kharbanda S, Ren R, Pandley P, et al. Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents. Nature. 1995;376:785-788.
-
(1995)
Nature
, vol.376
, pp. 785-788
-
-
Kharbanda, S.1
Ren, R.2
Pandley, P.3
-
26
-
-
0029134790
-
Defective induction of stress-activated protein kinase activity in ataxia-telangiectasia cells exposed to ionizing radiation
-
Shafman TD, Saleem A, Kyriakis J, Weichselbaum R, Kharbanda S, Kufe DW. Defective induction of stress-activated protein kinase activity in ataxia-telangiectasia cells exposed to ionizing radiation. Cancer Res. 1995;55:3242-3245.
-
(1995)
Cancer Res
, vol.55
, pp. 3242-3245
-
-
Shafman, T.D.1
Saleem, A.2
Kyriakis, J.3
Weichselbaum, R.4
Kharbanda, S.5
Kufe, D.W.6
-
27
-
-
0030041536
-
Persistant activation of c-Jun N-terminal kinase 1 (JNK1) in γ radiation-induced apoptosis
-
Chen Y-R, Meyer CF, Tan T-H. Persistant activation of c-Jun N-terminal kinase 1 (JNK1) in γ radiation-induced apoptosis. J Biol Chem. 1996;27:631-634.
-
(1996)
J Biol Chem
, vol.27
, pp. 631-634
-
-
Chen, Y.-R.1
Meyer, C.F.2
Tan, T.-H.3
-
28
-
-
0029417332
-
c-Abl activation regulates induction of the SEK1/stress-activated protein kinase pathway in the cellular response to 1-β-D-arabino-furanosylcytosine
-
Kharbanda S, Pandey P, Ren R, Mayer BJ, Zon L, Kufe D. c-Abl activation regulates induction of the SEK1/stress-activated protein kinase pathway in the cellular response to 1-β-D-arabino-furanosylcytosine. J Biol Chem. 1995;270:30278-30281.
-
(1995)
J Biol Chem
, vol.270
, pp. 30278-30281
-
-
Kharbanda, S.1
Pandey, P.2
Ren, R.3
Mayer, B.J.4
Zon, L.5
Kufe, D.6
-
29
-
-
0031985487
-
Transient stimulation of the c-Jun-NH2-terminal kinase/activator protein 1 pathway and inhibition of extracellular signal-regulated kinase are early effects in paclitaxel-mediated apoptosis in human B lymphoblasts
-
Amato SF, Swart JM, Berg M, Wanebo HJ, Mehta SR, Chiles TC. Transient stimulation of the c-Jun-NH2-terminal kinase/activator protein 1 pathway and inhibition of extracellular signal-regulated kinase are early effects in paclitaxel-mediated apoptosis in human B lymphoblasts. Cancer Res. 1998;58:241-247.
-
(1998)
Cancer Res
, vol.58
, pp. 241-247
-
-
Amato, S.F.1
Swart, J.M.2
Berg, M.3
Wanebo, H.J.4
Mehta, S.R.5
Chiles, T.C.6
-
30
-
-
0032561366
-
Paclitaxel (Taxol)-induced gene expression and cell death are both mediated by the activation of c-Jun NH2-terminal kinase (JNK/SAPK)
-
Lee L-F, Li G, Templeton DJ, Ting JP. Paclitaxel (Taxol)-induced gene expression and cell death are both mediated by the activation of c-Jun NH2-terminal kinase (JNK/SAPK). J Biol Chem. 1998;273:28253-28260.
-
(1998)
J Biol Chem
, vol.273
, pp. 28253-28260
-
-
Lee, L.-F.1
Li, G.2
Templeton, D.J.3
Ting, J.P.4
-
31
-
-
0029744885
-
Sounding the alarm: Protein kinase cascades activated by stress and inflammation
-
Kyriakis JM, Avruch J. Sounding the alarm: protein kinase cascades activated by stress and inflammation. J Biol Chem. 1996;271:24313-24316.
-
(1996)
J Biol Chem
, vol.271
, pp. 24313-24316
-
-
Kyriakis, J.M.1
Avruch, J.2
-
32
-
-
0030712182
-
The protein kinase C activators phorbol esters and phosphatidylserine inhibit neutral sphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin
-
Mansat V, Laurent G, Levade T, Bettaïeb A, Jaffrezou JP. The protein kinase C activators phorbol esters and phosphatidylserine inhibit neutral sphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin. Cancer Res. 1997;57:5300-5304.
-
(1997)
Cancer Res
, vol.57
, pp. 5300-5304
-
-
Mansat, V.1
Laurent, G.2
Levade, T.3
Bettaïeb, A.4
Jaffrezou, J.P.5
-
33
-
-
0029889577
-
Protein kinase C inhibition induces apoptosis and ceramide production through activation of a neutral sphingomyelinase
-
Chmura SJ, Nodzenski E, Weichselbaum RR, Quintans J. Protein kinase C inhibition induces apoptosis and ceramide production through activation of a neutral sphingomyelinase. Cancer Res. 1996;56:2711-2714.
-
(1996)
Cancer Res
, vol.56
, pp. 2711-2714
-
-
Chmura, S.J.1
Nodzenski, E.2
Weichselbaum, R.R.3
Quintans, J.4
-
34
-
-
0027978352
-
Identification of a distinct pool of sphingomyelin involved in the sphingomyelin cycle
-
Linardic CM, Hannun YA. Identification of a distinct pool of sphingomyelin involved in the sphingomyelin cycle. J Biol Chem. 1994;269:23530-23537.
-
(1994)
J Biol Chem
, vol.269
, pp. 23530-23537
-
-
Linardic, C.M.1
Hannun, Y.A.2
-
35
-
-
0030846601
-
Natural resistance of acute myeloid leukemia cell lines to mitoxantrone is associated with lack of apoptosis
-
Bailly JD, Skladanowski A, Bettaieb A, Mansat V, Larsen AK, Laurent G. Natural resistance of acute myeloid leukemia cell lines to mitoxantrone is associated with lack of apoptosis. Leukemia. 1997;11:1523-1532.
-
(1997)
Leukemia
, vol.11
, pp. 1523-1532
-
-
Bailly, J.D.1
Skladanowski, A.2
Bettaieb, A.3
Mansat, V.4
Larsen, A.K.5
Laurent, G.6
-
36
-
-
0029836636
-
Opposite effects of tumor necrosis factor α on the sphingomyelin-ceramide pathway in two myeloid leukemia cell lines: Role of transverse sphingomyelin distribution in the plasma membrane
-
Bettaieb A, Record M, Cöe MG, et al. Opposite effects of tumor necrosis factor α on the sphingomyelin-ceramide pathway in two myeloid leukemia cell lines: role of transverse sphingomyelin distribution in the plasma membrane. Blood. 1996;88:1465-1472.
-
(1996)
Blood
, vol.88
, pp. 1465-1472
-
-
Bettaieb, A.1
Record, M.2
Cöe, M.G.3
-
37
-
-
0031964966
-
Restoration of TNF-α-induced ceramide generation in resistant human leukemia KG1a cells by the P-glycoprotein blocker PSC833
-
Bezombes C, Maestre N, Laurent G, Levade T, Bettaieb A, Jaffrézou JP. Restoration of TNF-α-induced ceramide generation in resistant human leukemia KG1a cells by the P-glycoprotein blocker PSC833. FASEB J. 1998;12:101-109.
-
(1998)
FASEB J
, vol.12
, pp. 101-109
-
-
Bezombes, C.1
Maestre, N.2
Laurent, G.3
Levade, T.4
Bettaieb, A.5
Jaffrézou, J.P.6
-
38
-
-
0034631827
-
Sphingomyelin hydrolysis to ceramide during the execution phase of apoptosis results from phospholipid scrambling and alters cell-surface morphology
-
Tepper AD, Ruurs P, Wiedmer T, Sims PJ, Borst J, van Blitterswijk WJ. Sphingomyelin hydrolysis to ceramide during the execution phase of apoptosis results from phospholipid scrambling and alters cell-surface morphology. J Cell Biol. 2000;150:155-164.
-
(2000)
J Cell Biol
, vol.150
, pp. 155-164
-
-
Tepper, A.D.1
Ruurs, P.2
Wiedmer, T.3
Sims, P.J.4
Borst, J.5
Van Blitterswijk, W.J.6
-
39
-
-
0032486257
-
Sphingomyelin synthase, a potential regulator of intracellular levels of ceramide and diacylglycerol during SV40 transformation: Does sphingomyelin synthase account for the putative phosphatidylcholine-specific phospholipase C?
-
Luberto C, Hannun YA. Sphingomyelin synthase, a potential regulator of intracellular levels of ceramide and diacylglycerol during SV40 transformation: does sphingomyelin synthase account for the putative phosphatidylcholine-specific phospholipase C? J Biol Chem. 1998;273:14550-14559.
-
(1998)
J Biol Chem
, vol.273
, pp. 14550-14559
-
-
Luberto, C.1
Hannun, Y.A.2
-
40
-
-
0024392736
-
Sphingomyelin synthase and PKC activation
-
Hampton RY, Morand OH. Sphingomyelin synthase and PKC activation. Science. 1989;246:1050.
-
(1989)
Science
, vol.246
, pp. 1050
-
-
Hampton, R.Y.1
Morand, O.H.2
-
41
-
-
0038035591
-
Stress-induced apoptosis is not mediated by endolysosomal ceramide
-
Ségui B, Bezombes C, Uro-Costes E, et al. Stress-induced apoptosis is not mediated by endolysosomal ceramide. FASEB J. 2000;14:36-47.
-
(2000)
FASEB J
, vol.14
, pp. 36-47
-
-
Ségui, B.1
Bezombes, C.2
Uro-Costes, E.3
-
42
-
-
0028848344
-
Differential regulation of sphingomyelinase and ceramidase activities by growth factors and cytokines: Implications for cellular proliferation and differentiation
-
Coroneos E, Martinez M, McKenna S, Kester M. Differential regulation of sphingomyelinase and ceramidase activities by growth factors and cytokines: implications for cellular proliferation and differentiation. J Biol Chem. 1995;270:23305-23309.
-
(1995)
J Biol Chem
, vol.270
, pp. 23305-23309
-
-
Coroneos, E.1
Martinez, M.2
McKenna, S.3
Kester, M.4
-
43
-
-
0029948396
-
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate
-
Cuvillier O, Pirianov G, Kleuser B, et al. Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate. Nature. 1996;381:800-803.
-
(1996)
Nature
, vol.381
, pp. 800-803
-
-
Cuvillier, O.1
Pirianov, G.2
Kleuser, B.3
-
44
-
-
0032579414
-
Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes
-
Cuvillier O, Rosenthal DS, Smulson ME, Spiegel S. Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes. J Biol Chem. 1998;273:2910-2916.
-
(1998)
J Biol Chem
, vol.273
, pp. 2910-2916
-
-
Cuvillier, O.1
Rosenthal, D.S.2
Smulson, M.E.3
Spiegel, S.4
-
45
-
-
0032056362
-
1α,25-dihydroxyvitamin D3 inhibits programmed cell death in HL-60 cells by activation of sphingosine kinase
-
Kleuser B, Cuvillier O, Spiegel S. 1α,25-dihydroxyvitamin D3 inhibits programmed cell death in HL-60 cells by activation of sphingosine kinase. Cancer Res. 1998;58:1817-1824.
-
(1998)
Cancer Res
, vol.58
, pp. 1817-1824
-
-
Kleuser, B.1
Cuvillier, O.2
Spiegel, S.3
-
46
-
-
0030694255
-
Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction
-
Perez GI, Knudson CM, Leykin L, Korsmeyer SJ, Tilly JL. Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction. Nat Med. 1997;3:1228-1232.
-
(1997)
Nat Med
, vol.3
, pp. 1228-1232
-
-
Perez, G.I.1
Knudson, C.M.2
Leykin, L.3
Korsmeyer, S.J.4
Tilly, J.L.5
-
47
-
-
0026322568
-
Modulation of renal epithelial cell growth by glucosylceramide: Association with protein kinase C, sphingosine, and diacylglycerol
-
Shayman JA, Deshmukh GD, Mahdiyoun S, et al. Modulation of renal epithelial cell growth by glucosylceramide: association with protein kinase C, sphingosine, and diacylglycerol. J Biol Chem. 1991;266:22968-22974.
-
(1991)
J Biol Chem
, vol.266
, pp. 22968-22974
-
-
Shayman, J.A.1
Deshmukh, G.D.2
Mahdiyoun, S.3
-
48
-
-
0028913218
-
Structural and stereochemical studies of potent inhibitors of glucosylceramide synthase and tumor cell growth
-
Abe A, Radin NS, Shayman JA, et al. Structural and stereochemical studies of potent inhibitors of glucosylceramide synthase and tumor cell growth. J Lipid Res. 1995;36:611-621.
-
(1995)
J Lipid Res
, vol.36
, pp. 611-621
-
-
Abe, A.1
Radin, N.S.2
Shayman, J.A.3
-
49
-
-
0028878829
-
Cell cycle arrest induced by an inhibitor of glucosylceramide synthase: Correlation with cyclin-dependent kinases
-
Rani CS, Abe A, Chang Y, et al. Cell cycle arrest induced by an inhibitor of glucosylceramide synthase: correlation with cyclin-dependent kinases. J Biol Chem. 1995;270:2859-2867.
-
(1995)
J Biol Chem
, vol.270
, pp. 2859-2867
-
-
Rani, C.S.1
Abe, A.2
Chang, Y.3
-
50
-
-
0000255378
-
Expression of glucosylceramide synthase, converting ceramide to glucosylceramide, confers adriamycin resistance in human breast cancer cells
-
Liu YY, Han TY, Giulano AE, Cabot MC. Expression of glucosylceramide synthase, converting ceramide to glucosylceramide, confers adriamycin resistance in human breast cancer cells. J Biol Chem. 1999;274:1140-1146.
-
(1999)
J Biol Chem
, vol.274
, pp. 1140-1146
-
-
Liu, Y.Y.1
Han, T.Y.2
Giulano, A.E.3
Cabot, M.C.4
-
51
-
-
0031019309
-
Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells
-
Lavie Y, Cao H-T, Volner A, et al. Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells. J Biol Chem. 1997;272:1682-1687.
-
(1997)
J Biol Chem
, vol.272
, pp. 1682-1687
-
-
Lavie, Y.1
Cao, H.-T.2
Volner, A.3
-
52
-
-
0034629305
-
Uncoupling ceramide glycosylation by transfection of glucosylceramide synthase antisense reverses adriamycin resistance
-
Liu Y-Y, Han T-Y, Giulano AE, Hansen N, Cabot MC. Uncoupling ceramide glycosylation by transfection of glucosylceramide synthase antisense reverses adriamycin resistance. J Biol Chem. 2000;275:7138-7143.
-
(2000)
J Biol Chem
, vol.275
, pp. 7138-7143
-
-
Liu, Y.-Y.1
Han, T.-Y.2
Giulano, A.E.3
Hansen, N.4
Cabot, M.C.5
-
53
-
-
0345621659
-
Alteration of the daunorubicin-triggered sphingomyelin-ceramide pathway and apoptosis in MDR cells: Influence of drug transport abnormalities
-
Come MG, Bettaieb A, Skladanowski A, Larsen AK, Laurent G. Alteration of the daunorubicin-triggered sphingomyelin-ceramide pathway and apoptosis in MDR cells: influence of drug transport abnormalities. Int J Cancer. 1999;81:580-587.
-
(1999)
Int J Cancer
, vol.81
, pp. 580-587
-
-
Come, M.G.1
Bettaieb, A.2
Skladanowski, A.3
Larsen, A.K.4
Laurent, G.5
-
54
-
-
0029761340
-
Accumulation of glucosylceramide in multi-drug-resistant cancer cells
-
Lavie Y, Cao H-t, Bursten SL, Giulano AE, Cabot MC. Accumulation of glucosylceramide in multi-drug-resistant cancer cells. J Biol Chem. 1996;271:19530-19536.
-
(1996)
J Biol Chem
, vol.271
, pp. 19530-19536
-
-
Lavie, Y.1
Cao, H.-T.2
Bursten, S.L.3
Giulano, A.E.4
Cabot, M.C.5
-
55
-
-
0031899553
-
Glucosylceramide: A marker for multiple-drug resistant cancers
-
Lucci A, Cho WI, Han TY, Giulano AE, Cabot MC. Glucosylceramide: a marker for multiple-drug resistant cancers. Anticancer Res. 1998;18:475-480.
-
(1998)
Anticancer Res
, vol.18
, pp. 475-480
-
-
Lucci, A.1
Cho, W.I.2
Han, T.Y.3
Giulano, A.E.4
Cabot, M.C.5
-
56
-
-
0033194699
-
Modification of ceramide metabolism increases cancer cell sensitivity to cytotoxics
-
Lucci A, Han TY, Liu YY, Giuliano AE, Cabot MC. Modification of ceramide metabolism increases cancer cell sensitivity to cytotoxics. Int J Oncol. 1999;15:541-546.
-
(1999)
Int J Oncol
, vol.15
, pp. 541-546
-
-
Lucci, A.1
Han, T.Y.2
Liu, Y.Y.3
Giuliano, A.E.4
Cabot, M.C.5
-
57
-
-
0033565728
-
Multidrug resistance modulators and doxorubicin synergize to elevate ceramide levels and elicit apoptosis in drug-resistant cancer cells
-
Lucci A, Han TY, Liu YY, Giuliano AE, Cabot MC. Multidrug resistance modulators and doxorubicin synergize to elevate ceramide levels and elicit apoptosis in drug-resistant cancer cells. Cancer. 1999;86:299-310.
-
(1999)
Cancer
, vol.86
, pp. 299-310
-
-
Lucci, A.1
Han, T.Y.2
Liu, Y.Y.3
Giuliano, A.E.4
Cabot, M.C.5
-
58
-
-
0033557521
-
SDPSC 833, the cyclosporin A analogue and multi-drug resistance modulator, activates ceramide synthesis and increases vinblastine sensitivity in drug-sensitive and drug-resistant cancer cells
-
Cabot MC, Giulano AE, Han T-Y, Liu Y-Y. SDPSC 833, the cyclosporin A analogue and multi-drug resistance modulator, activates ceramide synthesis and increases vinblastine sensitivity in drug-sensitive and drug-resistant cancer cells. Cancer Res. 1999;59:880-885.
-
(1999)
Cancer Res
, vol.59
, pp. 880-885
-
-
Cabot, M.C.1
Giulano, A.E.2
Han, T.-Y.3
Liu, Y.-Y.4
-
59
-
-
0033590140
-
Inhibition of P-glycoprotein activity and chemosensitization of multidrug-resistant ovarian carcinoma 2780 AD cells by dexanoyl glucosylceramide
-
Veldman RJ, Sietsma H, Klappa K, Hoeckstr D, Kok JW. Inhibition of P-glycoprotein activity and chemosensitization of multidrug-resistant ovarian carcinoma 2780 AD cells by dexanoyl glucosylceramide. Biochem Res Commun. 1999;266:492-496.
-
(1999)
Biochem Res Commun
, vol.266
, pp. 492-496
-
-
Veldman, R.J.1
Sietsma, H.2
Klappa, K.3
Hoeckstr, D.4
Kok, J.W.5
-
60
-
-
0030983329
-
Influence of Bcl-2 overexpression on the ceramide pathway in daunorubicin-induced apoptosis of leukemic cells
-
Allouche M, Bettaïeb A, Vindis C, Rousse A, Grignon C, Laurent G. Influence of Bcl-2 overexpression on the ceramide pathway in daunorubicin-induced apoptosis of leukemic cells. Oncogene. 1997;14:1837-1845.
-
(1997)
Oncogene
, vol.14
, pp. 1837-1845
-
-
Allouche, M.1
Bettaïeb, A.2
Vindis, C.3
Rousse, A.4
Grignon, C.5
Laurent, G.6
-
61
-
-
0028851406
-
Inhibition of ceramide-induced apoptosis by Bcl-2
-
Martin SJ, Takayama S, McGahon A, et al. Inhibition of ceramide-induced apoptosis by Bcl-2. Cell Death Differ. 1995;2:253-257.
-
(1995)
Cell Death Differ
, vol.2
, pp. 253-257
-
-
Martin, S.J.1
Takayama, S.2
McGahon, A.3
-
62
-
-
0028046589
-
Attenuation of ceramide-induced apoptosis by diglyceride in human myeloid leukemia cells
-
Jarvis WDJ, Fornari FA, Browning JL, Gewirtz DA, Kolesnick RN, Grant SG. Attenuation of ceramide-induced apoptosis by diglyceride in human myeloid leukemia cells. J Biol Chem. 1994;269:31685-31692.
-
(1994)
J Biol Chem
, vol.269
, pp. 31685-31692
-
-
Jarvis, W.D.J.1
Fornari, F.A.2
Browning, J.L.3
Gewirtz, D.A.4
Kolesnick, R.N.5
Grant, S.G.6
-
63
-
-
0029922118
-
Induction of apoptosis and potentiation of ceramide-mediated cytotoxicity by sphingoid bases in human myeloid leukemia cells
-
Jarvis WD, Fornari FA, Traylor RS, et al. Induction of apoptosis and potentiation of ceramide-mediated cytotoxicity by sphingoid bases in human myeloid leukemia cells. J Biol Chem. 1996;271:8275-8284.
-
(1996)
J Biol Chem
, vol.271
, pp. 8275-8284
-
-
Jarvis, W.D.1
Fornari, F.A.2
Traylor, R.S.3
-
64
-
-
0027489710
-
Receptors for granulo-macrophage colony-stimulating factor, interleukin-3, and interleukin-5
-
Miyajima A, Mui AL-F, Ogorochi T, Sakamaki K. Receptors for granulo-macrophage colony-stimulating factor, interleukin-3, and interleukin-5. Blood. 1993;82:1960-1974.
-
(1993)
Blood
, vol.82
, pp. 1960-1974
-
-
Miyajima, A.1
Mui, A.L.-F.2
Ogorochi, T.3
Sakamaki, K.4
-
65
-
-
0026688428
-
Hematopoietic cytokines inhibit apoptosis induced by transforming growth factor β1 and cancer chemotherapy compounds in myeloid leukemic cells
-
Lotem J, Sachs L. Hematopoietic cytokines inhibit apoptosis induced by transforming growth factor β1 and cancer chemotherapy compounds in myeloid leukemic cells. Blood. 1992;80:1750-1757.
-
(1992)
Blood
, vol.80
, pp. 1750-1757
-
-
Lotem, J.1
Sachs, L.2
-
66
-
-
0029960946
-
Protection of human myeloid leukemic cells against doxorubicin-induced apoptosis by granulocyte-macrophage colony-stimulating factor and interleukin 3
-
Kaplinski C, Lotem J, Sachs L. Protection of human myeloid leukemic cells against doxorubicin-induced apoptosis by granulocyte-macrophage colony-stimulating factor and interleukin 3. Leukemia. 1996;10:460-465.
-
(1996)
Leukemia
, vol.10
, pp. 460-465
-
-
Kaplinski, C.1
Lotem, J.2
Sachs, L.3
-
67
-
-
0028285894
-
Effect of the protein kinase C inhibitor staurosporine on chemosensitivity to daunorubicin of normal and leukemic fresh myeloid cells
-
Laredo J, Huyn A, Muller C, et al. Effect of the protein kinase C inhibitor staurosporine on chemosensitivity to daunorubicin of normal and leukemic fresh myeloid cells. Blood. 1994;84:229-237.
-
(1994)
Blood
, vol.84
, pp. 229-237
-
-
Laredo, J.1
Huyn, A.2
Muller, C.3
-
68
-
-
85056020604
-
Kit activation inhibits daunorubicin-induced sphingomyelin cycle and apoptosis through a phospholipase Cγ and protein kinase C-dependent mechanism
-
Plo I, Lautier D, Casteran N, Dubreuil P, Arock M, Laurent G. Kit activation inhibits daunorubicin-induced sphingomyelin cycle and apoptosis through a phospholipase Cγ and protein kinase C-dependent mechanism. Hematolgie. 2001;7:25a.
-
(2001)
Hematolgie
, vol.7
-
-
Plo, I.1
Lautier, D.2
Casteran, N.3
Dubreuil, P.4
Arock, M.5
Laurent, G.6
-
69
-
-
0025309794
-
Free radicals and anti-cancer drug resistance: Oxygen free radicals in the mechanisms of drug cytotoxicity and resistance by certain tumors
-
Sinha BK, Mimmaugh EG. Free radicals and anti-cancer drug resistance: oxygen free radicals in the mechanisms of drug cytotoxicity and resistance by certain tumors. Free Radicals Biol Med. 1990;8:567-581.
-
(1990)
Free Radicals Biol Med
, vol.8
, pp. 567-581
-
-
Sinha, B.K.1
Mimmaugh, E.G.2
-
70
-
-
0025325945
-
Generation of daunomycin radicals on the outer side of the erythrocyte membrane
-
Pedersen JZ, Marcocci L, Rossi L, Mavelli I, Rotilio G. Generation of daunomycin radicals on the outer side of the erythrocyte membrane. Biochem Pharmacol. 1990;168:240-247.
-
(1990)
Biochem Pharmacol
, vol.168
, pp. 240-247
-
-
Pedersen, J.Z.1
Marcocci, L.2
Rossi, L.3
Mavelli, I.4
Rotilio, G.5
-
71
-
-
0021221088
-
Lipid peroxidation and possible hydroxyl radical formation stimulated by the self-reduction of a doxorubicin-iron (III) complex
-
Gutteridge JM. Lipid peroxidation and possible hydroxyl radical formation stimulated by the self-reduction of a doxorubicin-iron (III) complex. Biochem Pharmacol. 1984;33:1725-1728.
-
(1984)
Biochem Pharmacol
, vol.33
, pp. 1725-1728
-
-
Gutteridge, J.M.1
-
72
-
-
0032079524
-
Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-α-induced cell death
-
Liu B, Andrieu-Abadie N, Levade T, Zhang P, Obeid LM, Hannun YA. Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-α-induced cell death. J Biol Chem. 1998;273:11313-11320.
-
(1998)
J Biol Chem
, vol.273
, pp. 11313-11320
-
-
Liu, B.1
Andrieu-Abadie, N.2
Levade, T.3
Zhang, P.4
Obeid, L.M.5
Hannun, Y.A.6
-
73
-
-
0032493829
-
Cytokine-mediated induction of ceramide production is redox-sensitive
-
Singh I, Pahan K, Khan M, Singh A. Cytokine-mediated induction of ceramide production is redox-sensitive. J Biol Chem. 1998;273:20354-20362.
-
(1998)
J Biol Chem
, vol.273
, pp. 20354-20362
-
-
Singh, I.1
Pahan, K.2
Khan, M.3
Singh, A.4
-
74
-
-
1842330849
-
Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive species
-
Garcia-Ruiz C, Colell A, Mari M, Morales A, Fernandez-Checa JC. Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive species. J Biol Chem. 1997;272:11369-11377.
-
(1997)
J Biol Chem
, vol.272
, pp. 11369-11377
-
-
Garcia-Ruiz, C.1
Colell, A.2
Mari, M.3
Morales, A.4
Fernandez-Checa, J.C.5
-
75
-
-
1842375100
-
Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis
-
Quillet-Mary A, Jaffrézou JP, Mansat V, Bordier C, Naval J, Laurent G. Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis. J Biol Chem. 1997;272:21388-21395.
-
(1997)
J Biol Chem
, vol.272
, pp. 21388-21395
-
-
Quillet-Mary, A.1
Jaffrézou, J.P.2
Mansat, V.3
Bordier, C.4
Naval, J.5
Laurent, G.6
-
76
-
-
0028971742
-
Inhibition of apoptosis by antioxidants in the human HL-60 leukaemia cell line
-
Verhaegen S, McGowan AJ, Brophy AR, Fernandes RS, Cotter TG. Inhibition of apoptosis by antioxidants in the human HL-60 leukaemia cell line. Biochem Pharmacol. 1995;50:1021-1029.
-
(1995)
Biochem Pharmacol
, vol.50
, pp. 1021-1029
-
-
Verhaegen, S.1
McGowan, A.J.2
Brophy, A.R.3
Fernandes, R.S.4
Cotter, T.G.5
-
77
-
-
0028971265
-
Hydrogen peroxide- and fetal bovine serum-induced DNA synthesis in vascular smooth muscle cells: Positive and negative regulation by protein kinase C isoforms
-
Fiorani M, Cantoni O, Tasinato A, Boscoboinik D, Azzi A. Hydrogen peroxide- and fetal bovine serum-induced DNA synthesis in vascular smooth muscle cells: positive and negative regulation by protein kinase C isoforms. Biochim Biophys Acta. 1995;1269:98-104.
-
(1995)
Biochim Biophys Acta
, vol.1269
, pp. 98-104
-
-
Fiorani, M.1
Cantoni, O.2
Tasinato, A.3
Boscoboinik, D.4
Azzi, A.5
-
78
-
-
0031865214
-
Three distinct mechanisms for translocation and activation of the delta subspecies of protein kinase C
-
Ohmori S, Shirai Y, Sakai N, et al. Three distinct mechanisms for translocation and activation of the delta subspecies of protein kinase C. Mol Cell Biol. 1998;18:5263-5271.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 5263-5271
-
-
Ohmori, S.1
Shirai, Y.2
Sakai, N.3
-
79
-
-
0029770459
-
Tumor necrosis factor-alpha, platelet-activating factor, and hydrogen peroxide activate protein kinase C subtypes alpha and epsilon in human saphenous vein endothelial cells
-
Chen CC, Liau CS, Lee YT. Tumor necrosis factor-alpha, platelet-activating factor, and hydrogen peroxide activate protein kinase C subtypes alpha and epsilon in human saphenous vein endothelial cells. J Cardiovasc Pharmacol. 1996;28:240-244.
-
(1996)
J Cardiovasc Pharmacol
, vol.28
, pp. 240-244
-
-
Chen, C.C.1
Liau, C.S.2
Lee, Y.T.3
-
80
-
-
0027363407
-
NF-κB activation by ultraviolet light not dependent on a nuclear signal
-
Devary Y, Rosette C, DiDonato JA, Karin M. NF-κB activation by ultraviolet light not dependent on a nuclear signal. Science. 1993;261:1442-1445.
-
(1993)
Science
, vol.261
, pp. 1442-1445
-
-
Devary, Y.1
Rosette, C.2
DiDonato, J.A.3
Karin, M.4
-
81
-
-
0029737462
-
Activation of Raf by ionizing radiation
-
Kasid U, Suy S, Dent P, Ray S, Whiteside TL, Sturgill TW. Activation of Raf by ionizing radiation. Nature. 1996;382:813-816.
-
(1996)
Nature
, vol.382
, pp. 813-816
-
-
Kasid, U.1
Suy, S.2
Dent, P.3
Ray, S.4
Whiteside, T.L.5
Sturgill, T.W.6
-
82
-
-
0030849058
-
Association of Grb2 with Sos and Ras with Raf-1 upon gamma irradiation of breast cancer cells
-
Suy S, Anderson WB, Dent P, Chang E, Kasid U. Association of Grb2 with Sos and Ras with Raf-1 upon gamma irradiation of breast cancer cells. Oncogene. 1997;15:53-61.
-
(1997)
Oncogene
, vol.15
, pp. 53-61
-
-
Suy, S.1
Anderson, W.B.2
Dent, P.3
Chang, E.4
Kasid, U.5
-
84
-
-
0030886770
-
Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats
-
Aikawa AR, Komuro I, Yamazaki T, et al. Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats. J Clin Invest. 1997;100:1813-1821.
-
(1997)
J Clin Invest
, vol.100
, pp. 1813-1821
-
-
Aikawa, A.R.1
Komuro, I.2
Yamazaki, T.3
-
86
-
-
0028820298
-
A p53-independent pathway for activation of WAF1/CIP1 expression following oxidative stress
-
Russo T, Zambrano N, Esposito F, et al. A p53-independent pathway for activation of WAF1/CIP1 expression following oxidative stress. J Biol Chem. 1995;270:29386-29391.
-
(1995)
J Biol Chem
, vol.270
, pp. 29386-29391
-
-
Russo, T.1
Zambrano, N.2
Esposito, F.3
-
88
-
-
0028174061
-
Function and activation of NF-κB in the immune system
-
Baeuerle PA, Henkel T. Function and activation of NF-κB in the immune system. Annu Rev Immunol. 1994;12:141-179.
-
(1994)
Annu Rev Immunol
, vol.12
, pp. 141-179
-
-
Baeuerle, P.A.1
Henkel, T.2
-
89
-
-
0029858387
-
TNF-α cancer therapy-induced apoptosis: Potentiation by inhibition of NF-κB
-
Wang C-Y, Mayo MW, Baldwin AS. TNF-α and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB. Science. 1996;274:784-787.
-
(1996)
Science
, vol.274
, pp. 784-787
-
-
Wang, C.-Y.1
Mayo, M.W.2
Baldwin, A.S.3
-
90
-
-
0024389744
-
Protein kinase C in adriamycin action and resistance in mouse sarcoma 180 cells
-
Posada J, Vichi P, Tritton TR. Protein kinase C in adriamycin action and resistance in mouse sarcoma 180 cells. Cancer Res. 1989;49:6634-6639.
-
(1989)
Cancer Res
, vol.49
, pp. 6634-6639
-
-
Posada, J.1
Vichi, P.2
Tritton, T.R.3
-
91
-
-
0038027936
-
Daunorubicin- and mitoxantrone-triggered phosphatidylcholine hydrolysis: Implication in drug-induced ceramide generation
-
Bettaieb A, Plo I, Mansat-De Mas V, et al. Daunorubicin- and mitoxantrone-triggered phosphatidylcholine hydrolysis: implication in drug-induced ceramide generation. Mol Pharmacol. 1999;55:118-125.
-
(1999)
Mol Pharmacol
, vol.55
, pp. 118-125
-
-
Bettaieb, A.1
Plo, I.2
Mansat-De Mas, V.3
-
92
-
-
0029000942
-
Ceramide: A signal for apoptosis or mitogenesis?
-
Kolesnick R, Fuks Z. Ceramide: a signal for apoptosis or mitogenesis? J Exp Med. 1995;181:1949-1952.
-
(1995)
J Exp Med
, vol.181
, pp. 1949-1952
-
-
Kolesnick, R.1
Fuks, Z.2
-
93
-
-
0029097310
-
Evidence for a bifurcation of the mitogenic signaling pathway activated by Ras and phosphatidylcholine-hydrolyzing phospholipase C
-
Bjorkoy G, Overvathn A, Diaz-Meco MT, Moscat J, Johansen T. Evidence for a bifurcation of the mitogenic signaling pathway activated by Ras and phosphatidylcholine-hydrolyzing phospholipase C. J Biol Chem. 1995;270:21299-21306.
-
(1995)
J Biol Chem
, vol.270
, pp. 21299-21306
-
-
Bjorkoy, G.1
Overvathn, A.2
Diaz-Meco, M.T.3
Moscat, J.4
Johansen, T.5
-
94
-
-
0030808066
-
Platelet-derived growth factor activation of mitogen-activated protein kinase depends on the sequential activation of phosphatidylcholine-specific phospholipase C, protein kinase C-δ and Raf-1
-
Van Dijk MCM, Hilkmann H, van Blitterswijk WJ. Platelet-derived growth factor activation of mitogen-activated protein kinase depends on the sequential activation of phosphatidylcholine-specific phospholipase C, protein kinase C-δ and Raf-1. Biochem J. 1997;325:303-307.
-
(1997)
Biochem J
, vol.325
, pp. 303-307
-
-
Van Dijk, M.C.M.1
Hilkmann, H.2
Van Blitterswijk, W.J.3
-
95
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science. 1995;270:1326-1331.
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
96
-
-
0031450606
-
Antisense raf oligodeoxyribonucleotide is protected by liposomal encapsulation and inhibits Raf-1 protein expression in vitro and in vivo: Implication for gene therapy of radioresistant cancer
-
Gokhale PC, Soldatenkov V, Wang FH, Rahman A, Dritschilo A, Kasid U. Antisense raf oligodeoxyribonucleotide is protected by liposomal encapsulation and inhibits Raf-1 protein expression in vitro and in vivo: implication for gene therapy of radioresistant cancer. Gene Ther. 1997;4:1289-1299.
-
(1997)
Gene Ther
, vol.4
, pp. 1289-1299
-
-
Gokhale, P.C.1
Soldatenkov, V.2
Wang, F.H.3
Rahman, A.4
Dritschilo, A.5
Kasid, U.6
-
97
-
-
0031550257
-
Evidence supporting a signal transduction pathway leading to the radiation-resistant phenotype in human tumor cells
-
Pirollo KF, Hao Z, Rait A, Ho CW, Chang EH. Evidence supporting a signal transduction pathway leading to the radiation-resistant phenotype in human tumor cells. Biochem Biophys Res Commun. 1997;230:196-201.
-
(1997)
Biochem Biophys Res Commun
, vol.230
, pp. 196-201
-
-
Pirollo, K.F.1
Hao, Z.2
Rait, A.3
Ho, C.W.4
Chang, E.H.5
-
98
-
-
0027178812
-
Protein kinase C δ isoform is critical for mitogenic signal transduction
-
Berra E, Diaz-Meco MT, Dominguez I, et al. Protein kinase C δ isoform is critical for mitogenic signal transduction. Cell. 1993;74:555-563.
-
(1993)
Cell
, vol.74
, pp. 555-563
-
-
Berra, E.1
Diaz-Meco, M.T.2
Dominguez, I.3
-
99
-
-
0030792007
-
Positioning atypical PKC isoforms in the UV-induced apoptotic signaling cascade
-
Berra E, Municio MM, Sanz L, Frutos S, Diaz-Meco MT, Moscat J. Positioning atypical PKC isoforms in the UV-induced apoptotic signaling cascade. Mol Cell Biol. 1997;17:4346-4354.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 4346-4354
-
-
Berra, E.1
Municio, M.M.2
Sanz, L.3
Frutos, S.4
Diaz-Meco, M.T.5
Moscat, J.6
-
100
-
-
0030836301
-
Atypical protein kinase C protects human leukemia cells against drug-induced apoptosis
-
Murray NR, Fields AP. Atypical protein kinase C protects human leukemia cells against drug-induced apoptosis. J Biol Chem. 1997;272:27521-27524.
-
(1997)
J Biol Chem
, vol.272
, pp. 27521-27524
-
-
Murray, N.R.1
Fields, A.P.2
-
101
-
-
0025119208
-
Evidence for a role of phosphatidylcholine-hydrolysing phospholipase C in the regulation of protein kinase C by ras and src oncogenes
-
Diaz-Laviada I, Larrodera P, Diaz-Meco MT, et al. Evidence for a role of phosphatidylcholine-hydrolysing phospholipase C in the regulation of protein kinase C by ras and src oncogenes. EMBO J. 1990;9:3907-3912.
-
(1990)
EMBO J
, vol.9
, pp. 3907-3912
-
-
Diaz-Laviada, I.1
Larrodera, P.2
Diaz-Meco, M.T.3
-
102
-
-
0028813980
-
Human IL-3 receptor signaling: Rapid induction of phosphatidylcholine hydrolysis is independent of protein kinase C but dependent on tyrosine phosphorylation in transfected NIH 3T3 cells
-
Rao P, Kitamura T, Miyajima A, Mufson RA. Human IL-3 receptor signaling: rapid induction of phosphatidylcholine hydrolysis is independent of protein kinase C but dependent on tyrosine phosphorylation in transfected NIH 3T3 cells. J Immunol. 1995;154:1664-1674.
-
(1995)
J Immunol
, vol.154
, pp. 1664-1674
-
-
Rao, P.1
Kitamura, T.2
Miyajima, A.3
Mufson, R.A.4
-
103
-
-
0028078771
-
Human interleukin-3 stimulates a phosphatidylcholine specific phospholipase C and protein kinase C translocation
-
Rao P, Mufson RA. Human interleukin-3 stimulates a phosphatidylcholine specific phospholipase C and protein kinase C translocation. Cancer Res. 1994;54:777-781.
-
(1994)
Cancer Res
, vol.54
, pp. 777-781
-
-
Rao, P.1
Mufson, R.A.2
-
104
-
-
0029812902
-
Function of the p55 tumor necrosis factor receptor "death domain" mediated by phosphatidylcholine-specific phospholipase C
-
Machleidt T, Krämer B, Adam D, et al. Function of the p55 tumor necrosis factor receptor "death domain" mediated by phosphatidylcholine-specific phospholipase C. J Exp Med. 1996;184:725-733.
-
(1996)
J Exp Med
, vol.184
, pp. 725-733
-
-
Machleidt, T.1
Krämer, B.2
Adam, D.3
-
105
-
-
0031039024
-
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-biphophate
-
Franke TF, Kaplan DR, Cantley LC, Toker A. Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-biphophate. Science. 1997;275:665-668.
-
(1997)
Science
, vol.275
, pp. 665-668
-
-
Franke, T.F.1
Kaplan, D.R.2
Cantley, L.C.3
Toker, A.4
-
106
-
-
0030907987
-
PI3K: Downstream AKTion blocks apoptosis
-
Franke TF, Kaplan DR, Cantley LC. PI3K: downstream AKTion blocks apoptosis. Cell. 1997;88:435-437.
-
(1997)
Cell
, vol.88
, pp. 435-437
-
-
Franke, T.F.1
Kaplan, D.R.2
Cantley, L.C.3
-
107
-
-
0028560447
-
Activation of protein kinase C family members by the novel polyphosphoinositides Ptdlns-3,4-P2 and Ptdlns-3,4,5-P3
-
Toker A, Meyer M, Reddy KK, et al. Activation of protein kinase C family members by the novel polyphosphoinositides Ptdlns-3,4-P2 and Ptdlns-3,4,5-P3. J Biol Chem. 1994;269:32358-32367.
-
(1994)
J Biol Chem
, vol.269
, pp. 32358-32367
-
-
Toker, A.1
Meyer, M.2
Reddy, K.K.3
-
108
-
-
0027535742
-
Activation of the ζ isozyme of protein kinase C by phosphatidyiinositol 3,4,5-triphosphate
-
Nakanishi H, Brewer KA, Exton JH. Activation of the ζ isozyme of protein kinase C by phosphatidyiinositol 3,4,5-triphosphate. J Biol Chem. 1993;268:13-16.
-
(1993)
J Biol Chem
, vol.268
, pp. 13-16
-
-
Nakanishi, H.1
Brewer, K.A.2
Exton, J.H.3
-
109
-
-
0344653108
-
Activation of phospholipase C-γ by phosphatidylinositol 3,4,5-triphosphate
-
Bae YS, Cantley LG, Chen C-S, Kim S-R, Kwon K-S, Rhee SG. Activation of phospholipase C-γ by phosphatidylinositol 3,4,5-triphosphate. J Biol Chem. 1998;273:4465-4469.
-
(1998)
J Biol Chem
, vol.273
, pp. 4465-4469
-
-
Bae, Y.S.1
Cantley, L.G.2
Chen, C.-S.3
Kim, S.-R.4
Kwon, K.-S.5
Rhee, S.G.6
-
110
-
-
0030066023
-
The phosphatidylinositol 3-kinase inhibitor wortmannin sensitizes murine fibroblasts and human tumor cells to radiation and blocks induction of p53 following DNA damage
-
Price BD, Youmell MB. The phosphatidylinositol 3-kinase inhibitor wortmannin sensitizes murine fibroblasts and human tumor cells to radiation and blocks induction of p53 following DNA damage. Cancer Res. 1996;56:246-250.
-
(1996)
Cancer Res
, vol.56
, pp. 246-250
-
-
Price, B.D.1
Youmell, M.B.2
-
111
-
-
0031034574
-
Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt
-
Kulik G, Klippel A, Weber MJ. Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt. Mol Cell Biol. 1997;17:1595-1606.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 1595-1606
-
-
Kulik, G.1
Klippel, A.2
Weber, M.J.3
-
112
-
-
0344417222
-
Phosphoinositide 3-kinase/Akt-mediated survival pathway is activated by daunorubicin in human acute myeloid leukemia cell lines
-
Plo I, Bettaieb A, Payrastre B, et al. Phosphoinositide 3-kinase/Akt-mediated survival pathway is activated by daunorubicin in human acute myeloid leukemia cell lines. FEBS Lett. 1999;452:150-154.
-
(1999)
FEBS Lett
, vol.452
, pp. 150-154
-
-
Plo, I.1
Bettaieb, A.2
Payrastre, B.3
-
113
-
-
0034033712
-
Sensitization of HL60 human apoptosis by inhibition of PI3-kinase survival signals
-
O'Gorman DM, Mc Kenna SL, McGahon AJ, Knox KA, Cotter TG. Sensitization of HL60 human apoptosis by inhibition of PI3-kinase survival signals. Leukemia. 2000;14:602-611.
-
(2000)
Leukemia
, vol.14
, pp. 602-611
-
-
O'Gorman, D.M.1
Mc Kenna, S.L.2
McGahon, A.J.3
Knox, K.A.4
Cotter, T.G.5
-
114
-
-
0030911052
-
Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras
-
Rodriguez-Viciana P, Warne PH, Khwaja A, et al. Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras. Cell. 1997;89:457-467.
-
(1997)
Cell
, vol.89
, pp. 457-467
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Khwaja, A.3
-
115
-
-
0025967280
-
Activation of phosphatidylinositol 3-kinase in cells expressing abl oncogene variants
-
Varticovski L, Daley GQ, Jackson P, Baltimore D, Cantley LC. Activation of phosphatidylinositol 3-kinase in cells expressing abl oncogene variants. Mol Cell Biol. 1991;11:1107-1113.
-
(1991)
Mol Cell Biol
, vol.11
, pp. 1107-1113
-
-
Varticovski, L.1
Daley, G.Q.2
Jackson, P.3
Baltimore, D.4
Cantley, L.C.5
-
116
-
-
0030710188
-
Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway
-
Skorski T, Bellacosa A, Nieborovska-Skorska M, et al. Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway. EMBO J. 1997;16:6151-6161.
-
(1997)
EMBO J
, vol.16
, pp. 6151-6161
-
-
Skorski, T.1
Bellacosa, A.2
Nieborovska-Skorska, M.3
-
117
-
-
0029063970
-
Phosphatidylinositol-3 kinase activity is regulated by BCR/ABL and is required for the growth of Philadelphia chromosome-positive cells
-
Skorski T, Kanakaraj P, Nieborovska-Skorska M, et al. Phosphatidylinositol-3 kinase activity is regulated by BCR/ABL and is required for the growth of Philadelphia chromosome-positive cells. Blood. 1995;86:726-736.
-
(1995)
Blood
, vol.86
, pp. 726-736
-
-
Skorski, T.1
Kanakaraj, P.2
Nieborovska-Skorska, M.3
-
118
-
-
0028437318
-
Analysis of the mitogenic pathway of the FLT3 receptor and characterization in its C terminal region of a specific binding site for the PI3-kinase
-
Casteran N, Rottapel R, Beslu N, Lecocq E, Birnbaum D, Dubreuil P. Analysis of the mitogenic pathway of the FLT3 receptor and characterization in its C terminal region of a specific binding site for the PI3-kinase. Cell Mol Biol. 1994;40:443-456.
-
(1994)
Cell Mol Biol
, vol.40
, pp. 443-456
-
-
Casteran, N.1
Rottapel, R.2
Beslu, N.3
Lecocq, E.4
Birnbaum, D.5
Dubreuil, P.6
-
119
-
-
1842333237
-
Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
-
Del Peso L, Gonzales-Garcia M, Page C, Herrera R, Nunez G. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science. 1997;278:687-689.
-
(1997)
Science
, vol.278
, pp. 687-689
-
-
Del Peso, L.1
Gonzales-Garcia, M.2
Page, C.3
Herrera, R.4
Nunez, G.5
-
120
-
-
0030904561
-
The PI 3-kinase/Akt signaling pathway delivers an apoptotic signal
-
Kennedy SG, Wagner AJ, Conzen SD, et al. The PI 3-kinase/Akt signaling pathway delivers an apoptotic signal. Genes Dev. 1997;11:701-713.
-
(1997)
Genes Dev
, vol.11
, pp. 701-713
-
-
Kennedy, S.G.1
Wagner, A.J.2
Conzen, S.D.3
-
121
-
-
0032515027
-
Regulation of cell death protease caspase-9 by phosphorylation
-
Cardone MH, Roy N, Stennicke HR, et al. Regulation of cell death protease caspase-9 by phosphorylation. Science. 1998;282:1318-1321.
-
(1998)
Science
, vol.282
, pp. 1318-1321
-
-
Cardone, M.H.1
Roy, N.2
Stennicke, H.R.3
-
122
-
-
0032569026
-
Inhibition of Akt kinase by cell-permeable ceramide and its implication for ceramide-induced apoptosis
-
Zhou H, Summers SA, Birbaum MJ, Pittman RN. Inhibition of Akt kinase by cell-permeable ceramide and its implication for ceramide-induced apoptosis. J Biol Chem. 1998;273:16568-16575.
-
(1998)
J Biol Chem
, vol.273
, pp. 16568-16575
-
-
Zhou, H.1
Summers, S.A.2
Birbaum, M.J.3
Pittman, R.N.4
-
123
-
-
0029997148
-
Topoisimerase poisons activate the transcription factor NF-kappaB in ACH-2 and CEM cells
-
Piret B, Pirette J. Topoisimerase poisons activate the transcription factor NF-kappaB in ACH-2 and CEM cells. Nucleic Acids Res. 1996;24:4242-4248.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 4242-4248
-
-
Piret, B.1
Pirette, J.2
-
124
-
-
0030612721
-
Daunorubicin activates NFκB and induces κB-dependent gene expression in HL-60 promyelocytic and Jurkat T lymphoma cells
-
Boland MP, Foster SJ, O'Neill LAJ. Daunorubicin activates NFκB and induces κB-dependent gene expression in HL-60 promyelocytic and Jurkat T lymphoma cells. J Biol Chem. 1997;272:12952-12960.
-
(1997)
J Biol Chem
, vol.272
, pp. 12952-12960
-
-
Boland, M.P.1
Foster, S.J.2
O'Neill, L.A.J.3
-
125
-
-
0030610472
-
Activation of NF-κB by antineoplastic agents: Role of protein kinase C
-
Das KC, White CW. Activation of NF-κB by antineoplastic agents: role of protein kinase C. J Biol Chem. 1997;272:14914-14920.
-
(1997)
J Biol Chem
, vol.272
, pp. 14914-14920
-
-
Das, K.C.1
White, C.W.2
-
126
-
-
0032485072
-
Nuclear factor-κB-dependent regulation of p53 gene expression induced by daunomycin genotoxic drug
-
Hellin A-C, Calmant P, Gielin J, Bours V, Merville M-P. Nuclear factor-κB-dependent regulation of p53 gene expression induced by daunomycin genotoxic drug. Oncogene. 1998;16:1187-1195.
-
(1998)
Oncogene
, vol.16
, pp. 1187-1195
-
-
Hellin, A.-C.1
Calmant, P.2
Gielin, J.3
Bours, V.4
Merville, M.-P.5
-
127
-
-
0033558155
-
Stable inhibition of nuclear factor kB in cancer cells does not increase sensitivity to cytotoxic drugs
-
Bentires-Alj M, Hellin A-C, Ameyar M, Chouaib S, Merville M-P, Bours V. Stable inhibition of nuclear factor kB in cancer cells does not increase sensitivity to cytotoxic drugs. Cancer Res. 1999;59:811-815.
-
(1999)
Cancer Res
, vol.59
, pp. 811-815
-
-
Bentires-Alj, M.1
Hellin, A.-C.2
Ameyar, M.3
Chouaib, S.4
Merville, M.-P.5
Bours, V.6
-
128
-
-
0026542460
-
Activation of the transcription factor kB in human KG-1 myeloid leukemia cells treated with 1-β-D-Arabinofuranosylcytosine
-
Brach MA, Kharbanda SM, Herrmann F, Kufe DW. Activation of the transcription factor kB in human KG-1 myeloid leukemia cells treated with 1-β-D-Arabinofuranosylcytosine. Mol Pharmacol. 1991;41:60-63.
-
(1991)
Mol Pharmacol
, vol.41
, pp. 60-63
-
-
Brach, M.A.1
Kharbanda, S.M.2
Herrmann, F.3
Kufe, D.W.4
-
129
-
-
0029416976
-
Constitutive nuclear NF kappa B/rel DNA-binding activity of rat thymocytes is increased by stimuli that promote apoptosis, but not inhibited by pyrrolidine dithiocarbamate
-
Slater AF, Kimland M, Jiang SA, Orrenius S. Constitutive nuclear NF kappa B/rel DNA-binding activity of rat thymocytes is increased by stimuli that promote apoptosis, but not inhibited by pyrrolidine dithiocarbamate. Biochem J. 1995;312:833-838.
-
(1995)
Biochem J
, vol.312
, pp. 833-838
-
-
Slater, A.F.1
Kimland, M.2
Jiang, S.A.3
Orrenius, S.4
-
130
-
-
0026458406
-
TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown
-
Schutze SK, Potthoff T, Machleidt D, Berkovic K, Wiegmann K, Kronke M. TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown. Cell. 1992;71:765-771.
-
(1992)
Cell
, vol.71
, pp. 765-771
-
-
Schutze, S.K.1
Potthoff, T.2
Machleidt, D.3
Berkovic, K.4
Wiegmann, K.5
Kronke, M.6
-
131
-
-
1842376234
-
Serine-protease inhibitors block neutral sphingomyelinase activation, ceramide generation and apoptosis triggered by daunorubicin
-
Mansat V, Bettaieb A, Levade T, Laurent G, Jaffrézou JP. Serine-protease inhibitors block neutral sphingomyelinase activation, ceramide generation and apoptosis triggered by daunorubicin. FASEB J. 1997;11:695-702.
-
(1997)
FASEB J
, vol.11
, pp. 695-702
-
-
Mansat, V.1
Bettaieb, A.2
Levade, T.3
Laurent, G.4
Jaffrézou, J.P.5
-
132
-
-
0028334693
-
Inhibition of ceramide pathway does not affect ability of TN F-α to activate nuclear factor-κB
-
Johns LD, Sarr T, Ranges GE. Inhibition of ceramide pathway does not affect ability of TN F-α to activate nuclear factor-κB. J Immunol. 1994;152:5877-5882.
-
(1994)
J Immunol
, vol.152
, pp. 5877-5882
-
-
Johns, L.D.1
Sarr, T.2
Ranges, G.E.3
-
133
-
-
0028292774
-
Dissociation of endogenous cellular ceramide from N F-κB activation
-
Betts JC, Agranoff AB, Nabel GJ, Shayman JA. Dissociation of endogenous cellular ceramide from N F-κB activation. J Biol Chem. 1994;269:8455-8458.
-
(1994)
J Biol Chem
, vol.269
, pp. 8455-8458
-
-
Betts, J.C.1
Agranoff, A.B.2
Nabel, G.J.3
Shayman, J.A.4
-
134
-
-
0032588389
-
Activation of IkappaB kinase beta by protein kinase C isoforms
-
Lallena MJ, Diaz-Meco MT, Bren G, Paya CV, Moscat J. Activation of IkappaB kinase beta by protein kinase C isoforms. Mol Cell Biol. 1999;19:2180-2188.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 2180-2188
-
-
Lallena, M.J.1
Diaz-Meco, M.T.2
Bren, G.3
Paya, C.V.4
Moscat, J.5
-
135
-
-
0033517189
-
NF-κB activation by tumour necrosis factor requires the Akt serine-threonine kinase
-
Nidai Ozes O, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM, Donner DB. NF-κB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature. 1999;401:82-85.
-
(1999)
Nature
, vol.401
, pp. 82-85
-
-
Nidai Ozes, O.1
Mayo, L.D.2
Gustin, J.A.3
Pfeffer, S.R.4
Pfeffer, L.M.5
Donner, D.B.6
-
136
-
-
0033517190
-
NF-κB is a target of AKT in anti-apoptotic PDGF signalling
-
Remashkova JA, Makarov SS. NF-κB is a target of AKT in anti-apoptotic PDGF signalling. Nature. 1999;401:86-89.
-
(1999)
Nature
, vol.401
, pp. 86-89
-
-
Remashkova, J.A.1
Makarov, S.S.2
-
137
-
-
0029814063
-
Inhibition of NF-κB/Rel induces apoptosis of murine B cells
-
Wu M, Lee H, Bellas RE, et al. Inhibition of NF-κB/Rel induces apoptosis of murine B cells. EMBO J. 1996;15:4682-4690.
-
(1996)
EMBO J
, vol.15
, pp. 4682-4690
-
-
Wu, M.1
Lee, H.2
Bellas, R.E.3
-
138
-
-
18844465632
-
Constitutive nuclear factor-κB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells
-
Bargou RC, Emmerich F, Krappmann D, et al. Constitutive nuclear factor-κB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells. J Clin Invest. 1997;100:2961-2969.
-
(1997)
J Clin Invest
, vol.100
, pp. 2961-2969
-
-
Bargou, R.C.1
Emmerich, F.2
Krappmann, D.3
-
140
-
-
0029976817
-
An essential role for NF-κB in preventing TNF-α-induced cell death
-
Beg AA, Baltimore D. An essential role for NF-κB in preventing TNF-α-induced cell death. Science. 1996;274:782-784.
-
(1996)
Science
, vol.274
, pp. 782-784
-
-
Beg, A.A.1
Baltimore, D.2
-
141
-
-
0029992609
-
Suppression of TNF-α-induced apoptosis by NF-κB
-
Van Antwerp DJ, Martin SJ, Kafri T, Green DR, Verma IM. Suppression of TNF-α-induced apoptosis by NF-κB. Science. 1996;274:787-789.
-
(1996)
Science
, vol.274
, pp. 787-789
-
-
Van Antwerp, D.J.1
Martin, S.J.2
Kafri, T.3
Green, D.R.4
Verma, I.M.5
-
142
-
-
0028929371
-
Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation
-
Brockman JA, Scherer DC, McKinsey TA, et al. Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation. Mol Cell Biol. 1995;15:2809-2818.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 2809-2818
-
-
Brockman, J.A.1
Scherer, D.C.2
McKinsey, T.A.3
-
143
-
-
0027980321
-
The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B
-
Palombello V, Rando O, Goldberg A, Maniatis T. The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B. Cell. 1994;78:773-785.
-
(1994)
Cell
, vol.78
, pp. 773-785
-
-
Palombello, V.1
Rando, O.2
Goldberg, A.3
Maniatis, T.4
-
144
-
-
0028867899
-
Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of IκB synthesis
-
Auphan N, DiDonato JA, Rosette C, Helmberg A, Karin M. Immunosuppression by glucocorticoids: inhibition of NF-κB activity through induction of IκB synthesis. Science. 1995;270:286-290.
-
(1995)
Science
, vol.270
, pp. 286-290
-
-
Auphan, N.1
DiDonato, J.A.2
Rosette, C.3
Helmberg, A.4
Karin, M.5
-
145
-
-
0028879819
-
Role of transcriptional activation of IkBa in mediation of immunosuppression by glucocorticoids
-
Scheinman RI, Cogswell PC, Lofquist AK, Baldwin AS. Role of transcriptional activation of IkBa in mediation of immunosuppression by glucocorticoids. Science. 1995;270:283-286.
-
(1995)
Science
, vol.270
, pp. 283-286
-
-
Scheinman, R.I.1
Cogswell, P.C.2
Lofquist, A.K.3
Baldwin, A.S.4
-
146
-
-
0032905030
-
Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB
-
Wang CY, Cusack JC Jr, Liu R, Baldwin AS Jr. Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB. Nat Med. 1999;5:412-417.
-
(1999)
Nat Med
, vol.5
, pp. 412-417
-
-
Wang, C.Y.1
Cusack J.C., Jr.2
Liu, R.3
Baldwin A.S., Jr.4
-
147
-
-
0033538336
-
Inactivation of the inhibitory κB protein kinase/nuclear factor κB pathway by Par-4 expression potentiates tumor necrosis factor α-induced apoptosis
-
Diaz-Meco MT, Lallena M-J, Monjas A, Frutos S, Moscat J. Inactivation of the inhibitory κB protein kinase/nuclear factor κB pathway by Par-4 expression potentiates tumor necrosis factor α-induced apoptosis. J Biol Chem. 1999;274:19606-19612.
-
(1999)
J Biol Chem
, vol.274
, pp. 19606-19612
-
-
Diaz-Meco, M.T.1
Lallena, M.-J.2
Monjas, A.3
Frutos, S.4
Moscat, J.5
-
148
-
-
0029935682
-
Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells
-
Friesen C, Herr I, Krammer PH, Debatin KM. Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells. Nat Med. 1996;2:574-577.
-
(1996)
Nat Med
, vol.2
, pp. 574-577
-
-
Friesen, C.1
Herr, I.2
Krammer, P.H.3
Debatin, K.M.4
-
149
-
-
0040419494
-
Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53
-
Müller M, Strand S, Hug H, et al. Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53. J Clin Invest. 1997;99:403-413.
-
(1997)
J Clin Invest
, vol.99
, pp. 403-413
-
-
Müller, M.1
Strand, S.2
Hug, H.3
-
150
-
-
0030752603
-
The CD95 (APO-1/Fas) system mediates drug-induced apoptosis in neuroblastoma cells
-
Fulda S, Sieverts H, Friesen C, Herr I, Debatin KM. The CD95 (APO-1/Fas) system mediates drug-induced apoptosis in neuroblastoma cells. Cancer Res. 1997;57:3823-3829.
-
(1997)
Cancer Res
, vol.57
, pp. 3823-3829
-
-
Fulda, S.1
Sieverts, H.2
Friesen, C.3
Herr, I.4
Debatin, K.M.5
-
151
-
-
0030670626
-
Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis
-
Herr I, Wilhelm D, Bohler T, Angel P, Debatin KM. Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis. EMBO J. 1997;16:6200-6208.
-
(1997)
EMBO J
, vol.16
, pp. 6200-6208
-
-
Herr, I.1
Wilhelm, D.2
Bohler, T.3
Angel, P.4
Debatin, K.M.5
-
152
-
-
0030806351
-
Comparison of apoptosis in wild-type and Fas-resistant cells: Chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions
-
Eischen CM, Kottke TJ, Martins LM, et al. Comparison of apoptosis in wild-type and Fas-resistant cells: chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions. Blood. 1997;90:935-943.
-
(1997)
Blood
, vol.90
, pp. 935-943
-
-
Eischen, C.M.1
Kottke, T.J.2
Martins, L.M.3
-
153
-
-
0030744833
-
Drug-induced apoptosis is associated with enhanced Fas (APO-1/CD95) ligand expression but occurs independently of Fas (APO-1/CD95) signaling in human T-acute lymphatic leukemia cells
-
Villunger A, Egle A, Kos M, et al. Drug-induced apoptosis is associated with enhanced Fas (APO-1/CD95) ligand expression but occurs independently of Fas (APO-1/CD95) signaling in human T-acute lymphatic leukemia cells. Cancer Res. 1997;57:3331-3334.
-
(1997)
Cancer Res
, vol.57
, pp. 3331-3334
-
-
Villunger, A.1
Egle, A.2
Kos, M.3
-
154
-
-
0033135406
-
Anticancer drugs induce caspase-8/FLICE activation and apoptosis in the absence of CD95 receptor/ligand interaction
-
Wesselborg S, Engels IH, Rossmann E, Los M, Schulze-Osthoff K. Anticancer drugs induce caspase-8/FLICE activation and apoptosis in the absence of CD95 receptor/ligand interaction. Blood. 1999;93:3053-3063.
-
(1999)
Blood
, vol.93
, pp. 3053-3063
-
-
Wesselborg, S.1
Engels, I.H.2
Rossmann, E.3
Los, M.4
Schulze-Osthoff, K.5
-
155
-
-
0033583191
-
Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs
-
Micheau O, Solary E, Hammann A, Dimanche-Boitrel M-T. Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs. J Biol Chem. 1999;274:7987-7992.
-
(1999)
J Biol Chem
, vol.274
, pp. 7987-7992
-
-
Micheau, O.1
Solary, E.2
Hammann, A.3
Dimanche-Boitrel, M.-T.4
-
156
-
-
0030868999
-
Ultraviolet radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1)
-
Rehemtulla A, Hamilton CA, Chinnaiyan AM, Dixit VM. Ultraviolet radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1). J Biol Chem. 1997;272:25783-25786.
-
(1997)
J Biol Chem
, vol.272
, pp. 25783-25786
-
-
Rehemtulla, A.1
Hamilton, C.A.2
Chinnaiyan, A.M.3
Dixit, V.M.4
-
157
-
-
0031943921
-
Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L
-
Aragane Y, Kulms D, Metze D, et al. Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L. J Cell Biol. 1998;140:171-182.
-
(1998)
J Cell Biol
, vol.140
, pp. 171-182
-
-
Aragane, Y.1
Kulms, D.2
Metze, D.3
-
158
-
-
0033517301
-
The tyrosine kinase Lck is required for CD95-independent caspase-8 activation and apoptosis in response to ionizing radiation
-
Belka C, Marini P, Lepple-Wienhues A, et al. The tyrosine kinase Lck is required for CD95-independent caspase-8 activation and apoptosis in response to ionizing radiation. Oncogene. 1999;18:4983-4992.
-
(1999)
Oncogene
, vol.18
, pp. 4983-4992
-
-
Belka, C.1
Marini, P.2
Lepple-Wienhues, A.3
-
159
-
-
15844412409
-
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95(Fas/Apo-1) death-inducing signaling complex
-
Muzio M, Chinnaiyan AM, Kischkel FC, et al. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95(Fas/Apo-1) death-inducing signaling complex. Cell. 1996;85:817-827.
-
(1996)
Cell
, vol.85
, pp. 817-827
-
-
Muzio, M.1
Chinnaiyan, A.M.2
Kischkel, F.C.3
-
160
-
-
0032532013
-
FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation
-
Kataoka T, Schroter M, Hahne M, et al. FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation. J Immunol. 1998;161:3936-3942.
-
(1998)
J Immunol
, vol.161
, pp. 3936-3942
-
-
Kataoka, T.1
Schroter, M.2
Hahne, M.3
-
161
-
-
0030762122
-
Cross-resistance of CD95 and drug-induced apoptosis as a consequence of deficient activation of caspases (ICE/Ced-3 proteases)
-
Los M, Herr I, Friesen C, Fulda S, Schulze-Osthoff K, Debatin KM. Cross-resistance of CD95 and drug-induced apoptosis as a consequence of deficient activation of caspases (ICE/Ced-3 proteases). Blood. 1997;90:3118-3129.
-
(1997)
Blood
, vol.90
, pp. 3118-3129
-
-
Los, M.1
Herr, I.2
Friesen, C.3
Fulda, S.4
Schulze-Osthoff, K.5
Debatin, K.M.6
-
162
-
-
0031041448
-
Cytokine response modifier A (CrmA) inhibits ceramide formation in response to tumor necrosis factor (TNF)-α: CrmA and Bcl-2 target distinct components in the apoptotic pathway
-
Dbaibo GS, Perry DK, Gamard CJ, et al. Cytokine response modifier A (CrmA) inhibits ceramide formation in response to tumor necrosis factor (TNF)-α: CrmA and Bcl-2 target distinct components in the apoptotic pathway. J Exp Med. 1997;185:481-490.
-
(1997)
J Exp Med
, vol.185
, pp. 481-490
-
-
Dbaibo, G.S.1
Perry, D.K.2
Gamard, C.J.3
-
163
-
-
0032900335
-
Ordering of ceramide formation, caspase activation, and mitochondrial charges during CD95 and DNA damage-induced apoptosis
-
Tepper AD, de Vries E, van Blitterswijk WJ, Borst J. Ordering of ceramide formation, caspase activation, and mitochondrial charges during CD95 and DNA damage-induced apoptosis. J Clin Invest. 1999;103:971-978.
-
(1999)
J Clin Invest
, vol.103
, pp. 971-978
-
-
Tepper, A.D.1
De Vries, E.2
Van Blitterswijk, W.J.3
Borst, J.4
-
164
-
-
0030884017
-
Fas-Fas ligand-based interactions between tumor cells and tumor-specific cytotoxic T lymphocytes: A lethal two-way street
-
Zeytun A, Hassuneh M, Nagarkatti M, Nagarkatti PS. Fas-Fas ligand-based interactions between tumor cells and tumor-specific cytotoxic T lymphocytes: a lethal two-way street. Blood. 1997;90:1952-1959.
-
(1997)
Blood
, vol.90
, pp. 1952-1959
-
-
Zeytun, A.1
Hassuneh, M.2
Nagarkatti, M.3
Nagarkatti, P.S.4
-
165
-
-
16144363507
-
Lymphocyte apoptosis induced by CD95 (APO-I/Fas) ligand-expressing tumor cells-a mechanism of immune evasion?
-
Strand S, Hofmann WJ, Hug H, et al. Lymphocyte apoptosis induced by CD95 (APO-I/Fas) ligand-expressing tumor cells-a mechanism of immune evasion? Nat Med. 1996;2:1361-1366.
-
(1996)
Nat Med
, vol.2
, pp. 1361-1366
-
-
Strand, S.1
Hofmann, W.J.2
Hug, H.3
-
166
-
-
0029913888
-
Sensitivity of multidrug-resistant tumor cell lines to immunologic effector cells
-
Schmidt-Wolf IG, Lefterova P, Johnston V, et al. Sensitivity of multidrug-resistant tumor cell lines to immunologic effector cells. Cell Immunol. 1996;169:85-90.
-
(1996)
Cell Immunol
, vol.169
, pp. 85-90
-
-
Schmidt-Wolf, I.G.1
Lefterova, P.2
Johnston, V.3
-
167
-
-
0031586323
-
Immunosensitisation of prostate carcinoma cell lines for lymphocytes (CTL, TIL, LAK)-mediated apoptosis via the Fas-Fas-ligand pathway of cytotoxicity
-
Frost P, Ng CP, Belldegrun A, Bonavida B. Immunosensitisation of prostate carcinoma cell lines for lymphocytes (CTL, TIL, LAK)-mediated apoptosis via the Fas-Fas-ligand pathway of cytotoxicity. Cell Immunol. 1997;180:70-83.
-
(1997)
Cell Immunol
, vol.180
, pp. 70-83
-
-
Frost, P.1
Ng, C.P.2
Belldegrun, A.3
Bonavida, B.4
-
168
-
-
0030966954
-
Sensitization of cancer cells treated with cytotoxic drugs to Fas-mediated cytotoxicity
-
Micheau O, Solary E, Hammann A, Martin F, Dimanche-Boitrel M-T. Sensitization of cancer cells treated with cytotoxic drugs to Fas-mediated cytotoxicity. J Natl Cancer Inst. 1997;89:783-789.
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 783-789
-
-
Micheau, O.1
Solary, E.2
Hammann, A.3
Martin, F.4
Dimanche-Boitrel, M.-T.5
-
169
-
-
0033012524
-
Decreased sensitivity of drug-resistant cells towards T cell cytotoxicity
-
Classen CF, Fulda S, Friesen C, Debatin KM. Decreased sensitivity of drug-resistant cells towards T cell cytotoxicity. Leukemia. 1999;13:410-418.
-
(1999)
Leukemia
, vol.13
, pp. 410-418
-
-
Classen, C.F.1
Fulda, S.2
Friesen, C.3
Debatin, K.M.4
-
170
-
-
0029847356
-
Impairment of Fas-antigen expression in adriamycin-resistant but not TNF-resistant MCF-7 tumor cells
-
Cai Z, Stancou R, Körner M, Chouaib S. Impairment of Fas-antigen expression in adriamycin-resistant but not TNF-resistant MCF-7 tumor cells. Int J Cancer. 1996;68:535-546.
-
(1996)
Int J Cancer
, vol.68
, pp. 535-546
-
-
Cai, Z.1
Stancou, R.2
Körner, M.3
Chouaib, S.4
-
171
-
-
0030897001
-
Selection for drug resistance results in resistance to Fas-mediated apoptosis
-
Landowski TH, Gleason-Guzman MC, Dalton W. Selection for drug resistance results in resistance to Fas-mediated apoptosis. Blood. 1997;89:1854-1861.
-
(1997)
Blood
, vol.89
, pp. 1854-1861
-
-
Landowski, T.H.1
Gleason-Guzman, M.C.2
Dalton, W.3
-
172
-
-
0029818857
-
Expression of Fas/CD95 and Bcl-2 by primitive hematopoietic progenitors freshly isolated from human fetal liver
-
Barcena A, Park SW, Banapour B, Muench MO, Mechetner E. Expression of Fas/CD95 and Bcl-2 by primitive hematopoietic progenitors freshly isolated from human fetal liver. Blood. 1996;88:2013-2025.
-
(1996)
Blood
, vol.88
, pp. 2013-2025
-
-
Barcena, A.1
Park, S.W.2
Banapour, B.3
Muench, M.O.4
Mechetner, E.5
-
173
-
-
0031037778
-
Expression and function of CD95 (FAS/apo-1) in leukemia-lymphoma tumour lines
-
Dirks W, Schöne S, Uphoff C, Quentmeier H, Pradella S, Drexler HG. Expression and function of CD95 (FAS/apo-1) in leukemia-lymphoma tumour lines. Br J Haematol. 1997;96:584-593.
-
(1997)
Br J Haematol
, vol.96
, pp. 584-593
-
-
Dirks, W.1
Schöne, S.2
Uphoff, C.3
Quentmeier, H.4
Pradella, S.5
Drexler, H.G.6
-
174
-
-
0031440744
-
Functional expression of Fas (CD95) in acute myeloid leukemia cells in the context of CD34 and CD38 expression: Possible correlation with sensitivity to chemotherapy
-
Iijima N, Miyamura K, Itou T, Tanimoto M, Sobue R, Saito H. Functional expression of Fas (CD95) in acute myeloid leukemia cells in the context of CD34 and CD38 expression: possible correlation with sensitivity to chemotherapy. Blood. 1997;90:4901-4909.
-
(1997)
Blood
, vol.90
, pp. 4901-4909
-
-
Iijima, N.1
Miyamura, K.2
Itou, T.3
Tanimoto, M.4
Sobue, R.5
Saito, H.6
-
175
-
-
0034551746
-
Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L-induced apoptosis of human acute leukemia cells
-
Wen J, Ramadevi N, Nguyen D, Perkins C, Worthington E, Bhalla K. Antileukemic drugs increase death receptor 5 levels and enhance Apo-2L-induced apoptosis of human acute leukemia cells. Blood. 2000;96:3900-3906.
-
(2000)
Blood
, vol.96
, pp. 3900-3906
-
-
Wen, J.1
Ramadevi, N.2
Nguyen, D.3
Perkins, C.4
Worthington, E.5
Bhalla, K.6
-
176
-
-
0032522463
-
p53-dependent and -independent regulation of the death receptor killer/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha
-
Sheikh MS, Burns TF, Huang Y, et al. p53-dependent and -independent regulation of the death receptor killer/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha. Cancer Res. 1998;58:1593-1598.
-
(1998)
Cancer Res
, vol.58
, pp. 1593-1598
-
-
Sheikh, M.S.1
Burns, T.F.2
Huang, Y.3
-
177
-
-
0027212267
-
Increase in sequence specific DNA binding by p53 following treatment with chemotherapeutic and DNA damaging agents
-
Tishler RB, Calderwood SK, Coleman N, Price BD. Increase in sequence specific DNA binding by p53 following treatment with chemotherapeutic and DNA damaging agents. Cancer Res. 1993;53:2212-2216.
-
(1993)
Cancer Res
, vol.53
, pp. 2212-2216
-
-
Tishler, R.B.1
Calderwood, S.K.2
Coleman, N.3
Price, B.D.4
-
178
-
-
0027944206
-
p53 status and the efficacy of cancer therapy in vivo
-
Lowe SW, Bodis S, McClatchey A, et al. p53 status and the efficacy of cancer therapy in vivo. Science. 1994;266:807-810.
-
(1994)
Science
, vol.266
, pp. 807-810
-
-
Lowe, S.W.1
Bodis, S.2
McClatchey, A.3
-
179
-
-
0027451668
-
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
-
Lowe SW, Ruley HE, Jacks T, Housman DE. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell. 1993;74:957-967.
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
Housman, D.E.4
-
180
-
-
0033118475
-
Apoptosis, p53, and tumor cell sensitivity to anticancer agents
-
Brown JM, Wouters BG. Apoptosis, p53, and tumor cell sensitivity to anticancer agents. Cancer Res. 1999;59:1391-1399.
-
(1999)
Cancer Res
, vol.59
, pp. 1391-1399
-
-
Brown, J.M.1
Wouters, B.G.2
-
181
-
-
0028172868
-
p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies
-
Wattel E, Preudhomme C, Hecquet B, et al. p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies. Blood. 1994;84:3148-3157.
-
(1994)
Blood
, vol.84
, pp. 3148-3157
-
-
Wattel, E.1
Preudhomme, C.2
Hecquet, B.3
-
182
-
-
0031860937
-
Expression of p53 predicts treatment failure in aggressive non-Hodgkin's lymphomas
-
Navaratnam S, Williams GJ, Rubinger M, et al. Expression of p53 predicts treatment failure in aggressive non-Hodgkin's lymphomas. Leuk Lymphoma. 1998;29:139-144.
-
(1998)
Leuk Lymphoma
, vol.29
, pp. 139-144
-
-
Navaratnam, S.1
Williams, G.J.2
Rubinger, M.3
-
183
-
-
0031034762
-
p53 status affects the rate of the onset but not the overall extent of doxorubicin-induced cell death in Rat-1 fibroblasts constitutively expressing c-Myc
-
Han J-W, Dionne CA, Kedersha NL, Goldmacher VS. p53 status affects the rate of the onset but not the overall extent of doxorubicin-induced cell death in Rat-1 fibroblasts constitutively expressing c-Myc. Cancer Res. 1997;57:176-182.
-
(1997)
Cancer Res
, vol.57
, pp. 176-182
-
-
Han, J.-W.1
Dionne, C.A.2
Kedersha, N.L.3
Goldmacher, V.S.4
-
184
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
El-Deiry WS, Tokino T, Velculescu VE, et al. WAF1, a potential mediator of p53 tumor suppression. Cell. 1993;75:817-825.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
-
185
-
-
0028916558
-
Decreased cytotoxic effects of doxorubicin in a human ovarian cancer-cell line expressing wild-type p53 and WAF1/CIP1 genes
-
Vikhanskaya F, D'Incalci M, Broggini M. Decreased cytotoxic effects of doxorubicin in a human ovarian cancer-cell line expressing wild-type p53 and WAF1/CIP1 genes. Int J Cancer. 1995;61:397-401.
-
(1995)
Int J Cancer
, vol.61
, pp. 397-401
-
-
Vikhanskaya, F.1
D'Incalci, M.2
Broggini, M.3
-
186
-
-
0030044160
-
Induction of the WAF1/CIP1 protein and apoptosis in human T-cell leukemia virus type I-transformed lymphocytes after treatment with adriamycin by using a p53-independent pathway
-
Gartenhaus RB, Wang P, Hoffmann P. Induction of the WAF1/CIP1 protein and apoptosis in human T-cell leukemia virus type I-transformed lymphocytes after treatment with adriamycin by using a p53-independent pathway. Proc Natl Acad Sci U S A. 1996;93:265-268.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 265-268
-
-
Gartenhaus, R.B.1
Wang, P.2
Hoffmann, P.3
-
187
-
-
0029102010
-
High levels of constitutive WAF1/Cip1 protein are associated with chemoresistance in acute myelogenous leukemia
-
Zhang W, Kornblau SM, Kobayashi T, Gambel A, Claxton D, Deisseroth AB. High levels of constitutive WAF1/Cip1 protein are associated with chemoresistance in acute myelogenous leukemia. Clin Cancer Res. 1995;1:1051-1057.
-
(1995)
Clin Cancer Res
, vol.1
, pp. 1051-1057
-
-
Zhang, W.1
Kornblau, S.M.2
Kobayashi, T.3
Gambel, A.4
Claxton, D.5
Deisseroth, A.B.6
-
189
-
-
0027971191
-
Activation of Src-like p56/p53-yn tyrosine kinase by ionizing radiation
-
Kharbanda S, Yuan ZM, Rubin E, Weichselbaum R, Kufe D. Activation of Src-like p56/p53-yn tyrosine kinase by ionizing radiation. J Biol Chem. 1994;269:20739-20743.
-
(1994)
J Biol Chem
, vol.269
, pp. 20739-20743
-
-
Kharbanda, S.1
Yuan, Z.M.2
Rubin, E.3
Weichselbaum, R.4
Kufe, D.5
-
190
-
-
0028169334
-
p56/p53-yn tyrosine kinase activation in mammalian cells treated with mitomycin C
-
Kharbanda S, Yuan ZM, Taneja N, Weichselbaum R, Kufe D. p56/p53-yn tyrosine kinase activation in mammalian cells treated with mitomycin C. Oncogene. 1994;9:3005-3011.
-
(1994)
Oncogene
, vol.9
, pp. 3005-3011
-
-
Kharbanda, S.1
Yuan, Z.M.2
Taneja, N.3
Weichselbaum, R.4
Kufe, D.5
-
192
-
-
0033032317
-
Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: A mechanism for small cell lung cancer growth and drug resistance in vivo
-
Sethi T, Rintou RC, Moore SM, et al. Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo. Nat Med. 1999;5:662-668.
-
(1999)
Nat Med
, vol.5
, pp. 662-668
-
-
Sethi, T.1
Rintou, R.C.2
Moore, S.M.3
-
193
-
-
0033105537
-
Cell adhesion mediated drug resistance (CAM-DR): Role of integrins and resistance to apoptosis in human myeloma cell lines
-
Damiano JS, Cress AE, Hazlehurst LA, Shtil AA, Dalton WS. Cell adhesion mediated drug resistance (CAM-DR): role of integrins and resistance to apoptosis in human myeloma cell lines. Blood. 1999;93:1658-1667.
-
(1999)
Blood
, vol.93
, pp. 1658-1667
-
-
Damiano, J.S.1
Cress, A.E.2
Hazlehurst, L.A.3
Shtil, A.A.4
Dalton, W.S.5
-
194
-
-
0032532648
-
Adhesion receptors as regulators of the hematopoietic process
-
Verfaillie CM. Adhesion receptors as regulators of the hematopoietic process. Blood. 1998;92:2609-2612.
-
(1998)
Blood
, vol.92
, pp. 2609-2612
-
-
Verfaillie, C.M.1
-
195
-
-
0032143452
-
Profiling expression patterns and isolating differentially expressed genes by cDNA microarray system with colorimetry detection
-
Chen JJW, Wu R, Yang PC, et al. Profiling expression patterns and isolating differentially expressed genes by cDNA microarray system with colorimetry detection. Genomics. 1998;51:313-324.
-
(1998)
Genomics
, vol.51
, pp. 313-324
-
-
Chen, J.J.W.1
Wu, R.2
Yang, P.C.3
-
196
-
-
0033891762
-
Monitoring the expression profiles of doxorubicin-induced and doxorubicin-resistant cancer cells by cDNA microarray
-
Kudoh K, Ramana M, Ravata R, et al. Monitoring the expression profiles of doxorubicin-induced and doxorubicin-resistant cancer cells by cDNA microarray. Cancer Res. 2000;60:4161-4166.
-
(2000)
Cancer Res
, vol.60
, pp. 4161-4166
-
-
Kudoh, K.1
Ramana, M.2
Ravata, R.3
-
197
-
-
0030999750
-
Apoptosis and the dilemma of cancer chemotherapy
-
Hannun YA. Apoptosis and the dilemma of cancer chemotherapy. Blood. 1997;89:1845-1853.
-
(1997)
Blood
, vol.89
, pp. 1845-1853
-
-
Hannun, Y.A.1
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