Adenovirus-mediated transfer of the p53 family genes, p73 and p51/p63 induces cell cycle arrest and apoptosis in colorectal cancer cell lines: Potential application to gene therapy of colorectal cancer

Gene Therapy

Volumn 8, Issue 18, 2001, Pages 1401-1408

  Sasaki, Y ^a   Morimoto, I ^a   Ishida, S ^a   Yamashita, T ^a   Imai, K ^a   Tokino, T ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Adenoviral vector; Apoptosis; Gene therapy; p51 p63; p53; p73

Indexed keywords

DOXORUBICIN; PROTEIN P51; PROTEIN P51A; PROTEIN P53; PROTEIN P63; PROTEIN P63 GAMMA; PROTEIN P73; PROTEIN P73 BETA; UNCLASSIFIED DRUG; VIRUS VECTOR;

ADENOVIRUS; ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CARCINOGENICITY; CELL GROWTH; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE MODEL; DRUG DELIVERY SYSTEM; DRUG EFFECT; FEMALE; GENE THERAPY; GENE TRANSFER; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MITOSIS INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; X RAY;

ADENOVIRIDAE; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOGENICITY TESTS; COLORECTAL NEOPLASMS; DNA-BINDING PROTEINS; DOXORUBICIN; GENE THERAPY; GENES, P53; GENES, TUMOR SUPPRESSOR; GENETIC VECTORS; HUMANS; MEMBRANE PROTEINS; MICE; MICE, NUDE; NUCLEAR PROTEINS; PHOSPHOPROTEINS; TRANS-ACTIVATORS; TRANSDUCTION, GENETIC; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0034834092     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301538     Document Type: Article

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