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Journal of Biological Chemistry

Volumn 277, Issue 7, 2002, Pages 5484-5489

PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy

(5) Mayo, Lindsey D a Dixon, Jack E a Durden, Donald L a Tonks, Nickolas K a Donner, David B a

a INDIANA UNIVERSITY SCHOOL OF MEDICINE (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOTHERAPY; DNA; GENES; PROTEINS; SIGNALING; STRESSES; TUMORS;

TUMOR SUPPRESSOR PROTEINS;

CELLS;

CELL DNA; ETOPOSIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN MDM2; PROTEIN P53; RETROVIRUS VECTOR;

ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CELL CYCLE; CELL DEATH; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; CYTOPLASM; DNA DAMAGE; DRUG SENSITIVITY; DRUG SENSITIZATION; GENE TARGETING; GENETIC TRANSDUCTION; GLIOBLASTOMA; HUMAN; HUMAN CELL; MITOSIS INHIBITION; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STRESS; TRANSACTIVATION;

BLOTTING, WESTERN; CELL CYCLE; CELL LINE; CELL NUCLEUS; CLONING, MOLECULAR; COLORING AGENTS; CYTOPLASM; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ETOPOSIDE; GENES, REPORTER; GLIOBLASTOMA; HUMANS; MICROSCOPY, CONFOCAL; MUTATION; NEOPLASMS; NUCLEAR PROTEINS; PHOSPHORIC MONOESTER HYDROLASES; PRECIPITIN TESTS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; PTEN PHOSPHOHYDROLASE; RETROVIRIDAE; SIGNAL TRANSDUCTION; TETRAZOLIUM SALTS; THIAZOLES; TRANSCRIPTION, GENETIC; TRANSDUCTION, GENETIC; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

UNIDENTIFIED RETROVIRUS;

EID: 0037085271 PISSN: 00219258 EISSN: None Source Type: Journal
DOI: 10.1074/jbc.M108302200 Document Type: Article

Times cited : (309)

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