The role of melanocortins in body weight regulation: Opportunities for the treatment of obesity

European Journal of Pharmacology

Volumn 440, Issue 2-3, 2002, Pages 141-157

  MacNeil, Douglas J ^a   Howard, Andrew D ^a   Guan, Xiaoming ^a   Fong, Tung M ^a   Nargund, Ravi P ^a   Bednarek, Maria A ^a   Goulet, Mark T ^a   Weinberg, David H ^a   Strack, Alison M ^a   Marsh, Donald J ^a   Chen, Howard Y ^a   Shen, Chun Pyn ^a   Chen, Airu S ^a   Rosenblum, Charles I ^a   MacNeil, Tanya ^a   Tota, Michael ^a   MacIntyre, Euan D ^a   Van der Ploeg, Lex H T ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

ACTH (adrenocorticotropic hormone); AgRP (agouti related protein); Energy homeostasis; Melanocortin receptor; Melanocortins; Neuropeptide; Obesity; POMC (proopiomelanocortin); Sexual function

Indexed keywords

AGOUTI PROTEIN; AGOUTI RELATED PROTEIN; ALPHA INTERMEDIN; BETA INTERMEDIN; BETA INTERMEDIN[11-22][11 (N ACETYLCYSTEINE) 14 [3 (2 NAPHTHYL) DEXTRO ALANINE] 18 CYSTEINE 22 ASPARTIC ACID AMIDE] 11,18 CYCLIC DISULFIDE; CORTICOTROPIN; GAMMA INTERMEDIN; HP 228; HS 024; LACTAM DERIVATIVE; MBP 10; MELANOCORTIN; MELANOCORTIN 1 RECEPTOR; MELANOCORTIN 2 RECEPTOR; MELANOCORTIN 3 RECEPTOR; MELANOCORTIN 4 RECEPTOR; MELANOCORTIN 5 RECEPTOR; MELANOCORTIN RECEPTOR; MESSENGER RNA; N ACETYL ALPHA INTERMEDIN[4-10]CYCLO[4 NORLEUCINE 5 ASPARTIC ACID 7 [3 (2 NAPHTHYL)ALANINE] 10 LYSINAMIDE]; NEUROPEPTIDE Y RECEPTOR; PEPTIDE; RO 27 3225; RO 27 46580; SILDENAFIL; UNCLASSIFIED DRUG;

ARTICLE; BRAIN REGION; CLINICAL TRIAL; DRUG EFFECT; DRUG MECHANISM; DRUG RECEPTOR BINDING; ENERGY EXPENDITURE; ENERGY METABOLISM; ERECTILE DYSFUNCTION; FEEDING BEHAVIOR; FOOD INTAKE; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; GENETIC MODEL; HUMAN; HYPOTHALAMUS; NERVE CELL; NONHUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN SYNTHESIS; RECEPTOR AFFINITY; RECEPTOR BINDING; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION; WEIGHT REDUCTION;

ANIMALS; ANTI-OBESITY AGENTS; BODY WEIGHT; GENE EXPRESSION; HUMANS; MELANOCYTE-STIMULATING HORMONES; OBESITY; RECEPTORS, CORTICOTROPIN; RECEPTORS, MELANOCORTIN;

EID: 0037066620     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)01425-5     Document Type: Article

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