Genetic studies of the mouse mutations mahogany and mahoganoid

Genetics

Volumn 146, Issue 4, 1997, Pages 1407-1415

  Miller, K A ^a   Gunn, T M ^b   Carrasquillo, M M ^a   Lamoreux, M L ^c   Galbraith, D B ^c   Barsh, G S ^a,d  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TRINITY COLLEGE   (United States)

^c TEXAS A AND M UNIVERSITY   (United States)

^d STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HORMONE RECEPTOR; INTERMEDIN; MELANIN;

ANIMAL TISSUE; ARTICLE; FEMALE; GENE MUTATION; GENETIC ANALYSIS; MALE; MELANOGENESIS; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SKIN COLOR;

ADRENOCORTICOTROPIC HORMONE; ALPHA-MSH; ANIMALS; CROSSES, GENETIC; FEMALE; HAIR COLOR; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MELANINS; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MUTATION; OBESITY; PHENOTYPE; PROTEIN BIOSYNTHESIS; PROTEINS; RECEPTORS, CORTICOTROPIN; RECEPTORS, MELANOCORTIN; SIGNAL TRANSDUCTION;

AGOUTI; ANIMALIA; SWIETENIA;

EID: 0030742789     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. BEECHEY, C. V., and A. G. SEARLE, 1978 Epistasy of extension alleles. Mouse News Lett. 59: 19.
2. BEECHEY, C.V., and A. G. SEARLE, 1979 Epistasy of nc over Ay. Mouse News Lett. 60: 45-47.
3. CARPENTER, K.J., andj. MAYER, 1958 Physiologic observations on yellow obesity in the mouse. Am. J. Physiol. 193: 499-504.
4. CASTLE, W. E., 1941 Influence of certain coat color mutations on body size in mice, rats, and rabbits. Genetics 26: 177-191.
5. CHILAJLANI, V., and J. E. S. WIKBERG, 1992 Molecular cloning and expression of the human melanocyte stimulating hormone receptor cDNA. FEES Lett. 309: 417-420.
6. COLEMAN, D. L., 1973 Effects of parabiosis of obese with diabetes and normal mice. Diabetologia 9: 294-298.
7. CONE, R. D., D. Lu, S. KOPPULA, D. I. VAGE, H. KI.UNGLAND et ai, 1996 The melanocortin receptors: agonists, antagonists, and the hormonal control of pigmentation. Recent Prog. Horm. Res. 51: 287-318.
8. DUHL, D.M.J., M. E. STEVENS, H. VRIELING, P.J. SAXON, M.W. MILLER et al., 1994a Pleiotropic effects of the mouse lethal yellow (A(y)) mutation explained by deletion of a maternally expressed gene and the simultaneous production of agouti fusion RNAs. Development 120: 1695-1708.
9. DUHL, D. M.J., H. VRIELING, K.A. MILLER, G. L. WOLFF and G. S. BARSH, 1994b Neomorphic agouti mutations in obese yellow mice. Nature Genet. 8: 59-65.
10. GANTZ, I., Y. KONDA, T. TASHIRO, Y. SHIMOTO, H. MIWA et al., 1993a Molecular cloning of a novel melanocortin receptor. J. Biol. Chem. 268: 8246-8250.
11. GANTZ, I., H. MIWA, Y. KONDA, Y. SHIMOTO, T. TASHIRO el al., 1993b Molecular cloning, expression, and gene localization of a 4th melanocortin receptor. J. Biol. Chem. 268: 15174-15179.
12. GESCHWIND, 1.1., 1966 Change in hair color in mice induced by injection of a MSH. Endocrinology 79: 1165-1167.
13. GESCHWIND, I. L, R. A. HUSEBY and R. NISHIOKA, 1972 The effect of melanpcyte -stimulating hormone on coat color in the mouse. Recent Prog. Horm. Res. 28: 91-130.
14. GREEN, M. C., 1989 Catalog of mutant genes and polymorphic loci, pp. 12-403 in Genetic Vtnianls and Strains of the Laboratory Mouse, edited by M. F. LYON and A. G. SEARLE. Oxford University Press, Oxford.
15. HUNT, G., and A.J. THODY, 1995 Agouti protein can act independently of melanocyte-stimulating hormone to inhibit melanogenesis.J. Endocrinol. 147: R1-R4.
16. HUSZAR, D., C. A. LYNCH, V. FAIRCHII.IHUTRESS, J. H. DUNMORE, Q. FANG et al, 1997 Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 88: 131-141.
17. JACKSON, I. J., 1994 Molecular and developmental genetics of mouse coat color. Annu. Rev. Genet. 28: 189-217.
18. JONES, B. H., J. H. HIM, M. B. ZEMEI, R. P. WOYCIIIK, E.J. MICIIAUD et al, 1996 Upregulation of adipocyte metabolism by agouti protein: possible paracrine actions in yellow mouse obesity. Am. J. Physiol. Endocrinol. Met. 33: E192-E19G.
19. KATUR, R. P., C. YOST and R. D. PAI.MITF.R, 1993 Aggregation chimeras demonstrate that the primär)- defect responsible for aganglionic megacolon in lethal-spotted mice is not neuroblast autonomous. Development 117: 993-999.
20. LAMOREUX, M. L., and D. B. GAI.BRAITH, 1986 DK/Lm: a strain of laboratory mouse with an unusual expression of the lethal yellow (Ay) phenotype. Genet. Res. 48: 35-40.
21. LANE, P. W., 1960 New mutants. Mouse News Lett. 22: 35.
22. LANE, P. W., and M. C. GREEN, I960 Mahogany, a recessive color mutatioin in linkage group V of the mouse. J. Hered. 51: 228230.
23. Lu, D. S., D. WiLiARD, I. R. PATEL, S. KADVEU., L. OVERTON et a!., 1994 Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor. Nature 371: 799-802.
24. MANNE.J., A. C. ARGESON and L. D. SIRACUSA, 1995 Mechanisms for the pleiotropic effects of the agouti gene. Proc. Nail. Acad. Sei. USA 92: 4721-4724.
25. McCuLLOCii, E. A., L. SIMINOVITCH.J. E. TILL, E. S. RUSSELL and S. E. BERNSTEIN, 1965 The cellular basis of the genetically determined hemopoietic defect in anemic mice of genotype Sl-Sld. Blood 26: 399-410.
26. MGD, 1996 Mouse Genome Database. Mouse Genome Informatics. The Jackson Laboratory, Bar Harbor, ME. World Wide Web (URL: http://www.informatics.jax.org/).
27. MICIIAUD, E. J., S.J. BUI.TMAN, M. L. KI.EBIG, V. M. VAN, L.J. STUBBS et al., 1994a A molecular model for the genetic and phenotypic characteristics of the mouse lethal yellow (Ay) mutation. Proc. Nail. Acad. Sei. USA 91: 2562-2566.
28. MICIIAUD, E.J., M.J. VANVUGT, S.J. BUI.TMAN, H. O. SVEET, M. T. DAVISSON et al., 1994b Differential expression of a new dominant agouti allele (A(iapy)) is correlated with methylation state and is influenced by parental lineage. Genes Dev. 8: 1463-1472.
29. MILLAR, S. E., M. W. MILLER, M. E. STE-ENS and G. S. BARSH, 1995 'Expression and transgenic studies of the mouse agouti gene provide insight into the mechanisms by which mammalian coat color patterns are generated. Development 121: 3223-3232.
30. MOUNTJOV, K. G., L. S. ROBBINS, M. T. MORTRUD and R. D. CONE, 1992 The cloning of a family of genes that encode the melanocortin receptors. Science 257: 1248-1251.
31. POOLE, T. W., 1975 Dermal-epidermal interactions and the action of alleles at the agouti locus in the mouse. Dev. Biol. 42: 203210.
32. ROBBINS, L. S.,J. H. NADEAU, K. R. JOHNSON, M. A. KELLY, L. ROSELI.IREHFUSS et al., 1993 'Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function. Cell 72: 827-834.
33. SIIIMIZU, H., N.S. SIIARGIIJ., G.A. BRAY, T.T. YEN and P.D. GESEI.I.CIIEN, 1989 Effects of MSH on food intake, body weight and coat color of the yellow obese mouse. Life Sei. 45: 543-552.
34. SILVERS, W. K., 1979 The Coat Colors of Mire: A Model for Mammalian Gene Action and Interaction. Springer-Verlag, N'ew York.
35. SILVERS, W. K., and E. S. RUSSELL, 1955 An experimental approach to action of genes at the agouti locus in the mouse. J. Exp. Zool. 130: 199-220.
36. SIRACUSA, L. D., 1994 The agouti gene: turned on to yellow. Trends Genet. 10: 423-428.
37. SI.OMINSKI, A., R. PAUS and J. WORTSMAX, 1993 On the potential role of proopiomelanocortin in skin physiology and pathology. Mol. Cell. Endocrinol. 93: C1-C6.
38. VRIEIJXCï, H., D.M. DUHL, S. E. MILLAR, K.A. MILLER and G. S. BARSH, 1994 Differences in dorsal and ventral pigmentation result from regional expressiontif the mouse agouti gene. Proc. Natl. Acad. Sei. USA 91: 567-5671.
39. WlLLARD, D. H., W. BODXAR, C. HARRIS, L. KlEFER.J. S. NlCHOLS et al., 1995 Agouti structure and function: characterization of a potent alpha-melanocyte stimulating hormone receptor antagonist. Biochemistry 34: 12341-12346.
40. WILSON, B. D., M. M. OIJ.MANN, L. RANG, M. STOFFEL, G. I. BELL et al., 1995 Structure and function of ASP, the human homolog of the mouse agouti gene. Hum. Mol. Genet. 4: 223-230.
41. WINTZEN, M., and B. A. GII.CHREST, 1996 Proopiomelanocortin, its derived peptides, and the skin.J. Invest. Dermatol. 106: 3-10.
42. WOLFF, G. L., D. B. GAI.BRAITH, O. E. DOMON and J. M. Row, 1978 Phaeomelanin synthesis and obesity in mice. Interaction of the viable yellow (Avy) and sombre (Eso) mutations. J. Hered. 69: 295-298.
43. YANG, Y. K., M. M. OI.I.MANN, B. D. WILSON, C. DICKJNSON, T. YAMADA et al., 1997 Effects of recombinant agouti-signaling protein on melanocortin action. Mol. Endocrinol. 11: 274-280.
44. YEN-, T. T., A. M. GILL, L. G. FRIGERI, G. S. BARSH and G. L. WOIJT, 1994 Obesity, diabetes, and neoplasia in yellow A(vy)/- mice: ectopic expression of the agouti gene. FASEBJ. 8: 479-488.
45. ZEMEL, M. B.,J. H. KIM, R. P. WOYCHIK, E.J. MICHAUD, S. H. KADU-ELL et al., 1995 Agouti regulation of intracellular calcium: role in the insulin resistance of viable yellow mice. Proc. Natl. Acad. Sei. USA 92: 4733-4737.