The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 6, 1997, Pages 2156-2161

  Pause, Arnim ^a   Lee, Stephen ^a   Worrell, Robert A ^b   Chen, David Y T ^b   Burgess, Wilson H ^c   Linehan, W Marston ^b   Klausner, Richard D ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c HOLLAND LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELONGATION FACTOR; GENE PRODUCT;

ARTICLE; DISEASE PREDISPOSITION; GENETIC TRANSCRIPTION; HEMANGIOBLASTOMA; IMMUNOFLUORESCENCE; PLASMID; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FAMILY; PROTEIN STABILITY; TRANSLATION INITIATION; TUMOR SUPPRESSOR GENE; VON HIPPEL LINDAU DISEASE;

AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS; CARRIER PROTEINS; CELL CYCLE PROTEINS; CELL LINE; CLONING, MOLECULAR; COS CELLS; CULLIN PROTEINS; CYTOSOL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENES, TUMOR SUPPRESSOR; HELA CELLS; HIPPEL-LINDAU DISEASE; HUMANS; LIGASES; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PEPTIDE FRAGMENTS; PROTEIN BIOSYNTHESIS; PROTEINS; RATS; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

CAENORHABDITIS ELEGANS;

EID: 0030953635     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.6.2156     Document Type: Article

References (31)

1. Linehan, W. M., Lerman, M. I., & Zbar, B. (1995) J. Am. Med. Assoc. 273, 564-570.
2. Gnarra, J. R., Duan, D. R., Weng, Y., Humphrey, J. S., Chen, D. Y., et al. (1996) Biochim. Biophys. Acta. 1242, 201-210.
3. Knudson, A. G. (1993) Proc. Natl. Acad. Sci. USA 90, 10914-10921.
4. Knudson, A. G. (1995) Cancer 1, 180-181.
5. Zbar B. (1995) Cancer Surv. 25, 219-232.
6. Zbar, B., Kishida, T., Chen, F., Schmidt, L., Maher, E. R., et al. (1996) Human Mutat. 8, 348-357.
7. Shuin, T., Kondo, K., Torigoe, S., Kishida, T., Kubota, Y., et al. (1994) Cancer Res. 54, 2852-2855.
8. Latif, F., Tory, K., Gnarra, J. R., Yao, M., Duh, F., et al. (1993) Science 260, 1317-1320.
9. Duan, D. R., Humphrey, J. S., Chen, D. Y. T., Weng, Y., Sukegawa, J., Lee, S., Gnarra, J. R., Linehan, W. M. & Klausner, R. D. (1995) Proc. Natl. Acad. Sci. USA 92, 6459-6463.
10. Duan, D. R., Pause, A., Burgess, W. H., Aso, T., Chen, D. Y. T., Garrett, K. P., Conaway, R. C., Conaway, J. W., Linehan, W. M. & Klausner, R. D. (1995) Science 269, 1402-1406.
11. Aso, T., Lane, W. S., Conaway, J. W. & Conaway, R. C. (1995) Science 269, 1439-1443.
12. Kibel, A., Iliopoulos, O., DeCaprio, J. A. & Kaelin, W. G., Jr. (1995) Science 269, 1444-1446.
13. Kishida, T., Stackhouse, T. M., Chen, F., Lerman, M. I. & Zbar, B. (1995) Cancer Res. 55, 4544-4548.
14. Siemeister, G., Weindel, K., Mohrs, K., Barleon, B., Martiny-Baron, G. & Marme, D. (1996) Cancer Res. 56, 2299-2301.
15. Gnarra, J. R., Zhou, S., Merrill, M. J., Wagner, J. R., Krumm, A., Papavassiliou, E., Olfield, E. H., Klausner, R. D. & Linehan, W. M. (1996) Proc. Natl. Acad. Sci. USA 93, 10589-10594.
16. Iliopoulos, O., Levy, A. P., Jiang, C., Kaelin, W. G., Jr., & Goldberg, M. A. (1996) Proc. Natl. Acad. Sci. USA 93, 10595-10599.
17. Stein, I., Neeman, M., Shweiki, D., Itin, A. & Keshet, E. (1995) Mol. Cell. Biol. 15, 5363-5368.
18. Levy, A. P., Levy, N. S. & Goldberg, M. A. (1996) J. Biol. Chem. 271, 2746-2753.
19. Pause, A., Aso, T., Linehan, W. M., Conaway, J. W., Conaway, R. C. & Klausner, R. D. (1996) Methods Enzymol. 274, 436-441.
20. Lee, S., Chen, D. Y. T., Humphrey, J. S., Gnarra, J. R., Linehan, W. M. & Klausner, R. D. (1996) Proc. Natl. Acad. Sci. USA 93, 1770-1775.
21. Cole, N. B., Sciaky, N., Marotta, A., Song, J. & Lipincott-Schwartz, J. (1996) Mol. Biol. Cell. 7, 631-650.
22. Kipreos, E. T., Lander, L. E., Wing, J. P., He, W. W. & Hedgecock, E. M. (1996) Cell 85, 829-839.
23. Goebl, M. G., Yochem, J., Jentsch, S., McGrath, J. P., Varshavsky, A. & Byers, B. (1988) Science 241, 1331-1335.
24. Schwob, E., Bohm, T., Mendenhall, M. D. & Nasmyth, K. (1994) Cell 79, 233-244.
25. Willems, A. R., Lanker, S., Patton, E. E., Craig, K. L., Nason, T. F., Mathias, N., Kobayashi, R., Wittenberg, C. & Tyers, M. (1996) Cell 86, 453-463.
26. Mathias, N., Johnson, S. L., Winey, M., Adams, A. E., Goetsch, L., Pringle, J. R., Byers, B. & Goebl, M. G. (1996) Mol. Cell. Biol. 16, 6634-6643.
27. Raff, M. C. (1996) Cell 86, 173-175.
28. Jackson, P. K. (1996) Curr. Biol. 6, 1209-1212.
29. Walther, M. M., Lubensky, I. A., Venzon, D., Zbar, B. & Linehan, W. M. (1995) J. Urol. 154, 2010-2014.
30. Lubensky, I. A., Gnarra, J. R., Bertheau, P., Walther, M. M., Linehan, W. M., Liotta, L. & Lubensky, I. A. (1996) Am. J. Pathol. 149, 2089-2095.
31. Kinzler, K. W. & Vogelstein, B. (1996) Cell 87, 159-170.